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公开(公告)号：US20230357500A1
公开(公告)日：2023-11-09
申请号：US18004910
申请日：2021-06-14
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Carl A. Laskowski , Timothy M. Gillard , Ranjani V. Parthasarathy , Hannah C. Cohen , Max A. Kruziki
IPC: C08G65/327 , C08G65/08 , C08G81/00 , A61K31/80
CPC classification number: C08G65/327 , C08G65/08 , C08G81/00 , A61K31/80 , C08G2650/58
Abstract: Phosphate-containing copolymers, medical compositions containing the phosphate-containing copolymers, and methods of suppressing microbial virulence are provided. By suppressing virulence, administration and/or application of the medical compositions can be used to prevent, mitigate, or treat a microbial infection. The phosphate-containing copolymers are prepared by phosphorylating either a random copolymer or a random copolymeric block that contains monomeric units of propylene oxide and glycidol.
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公开(公告)号：US11684069B2
公开(公告)日：2023-06-27
申请号：US14917185
申请日：2014-09-11
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Ranjani V. Parthasarathy , Matthew T. Scholz , Joshua X. Xiong , Catherine D. Heapy
IPC: A01N47/44 , A01N43/40 , A61K8/44 , A61K8/41 , A61K31/155 , A61K8/46 , A61K8/49 , A61K8/40 , A61K8/86 , A61K8/39 , A61K8/43 , A61Q11/00 , A61L26/00 , A61K8/55 , A61Q17/00 , A61K8/60 , A01N25/30
CPC classification number: A01N47/44 , A01N25/30 , A01N43/40 , A61K8/39 , A61K8/40 , A61K8/416 , A61K8/43 , A61K8/442 , A61K8/466 , A61K8/4926 , A61K8/4993 , A61K8/55 , A61K8/604 , A61K8/86 , A61K31/155 , A61L26/0066 , A61Q11/00 , A61Q17/005 , A61L2300/404 , A01N47/44 , A01N25/02 , A01N43/40 , A01N25/02
Abstract: An antiseptic composition comprising a multivalent cationic antiseptic present in an amount of 0.05 to 0.5 percent based upon the ready to use composition; an anionic compound which is water soluble in an amount of at least 0.1 grams in 100 grams water at 23 deg C., wherein the anionic compound is present at a concentration which would result in precipitation of the multivalent cationic antiseptic in the composition without a solubilizing surfactant present; wherein the composition, with the antiseptic, surfactant and anionic compound combined with each other, is free of precipitate.
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公开(公告)号：US20220288108A1
公开(公告)日：2022-09-15
申请号：US17633377
申请日：2020-08-28
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Kevin D. Landgrebe , Ranjani V. Parthasarathy , Katie F. Wlaschin
Abstract: Aspects of the present disclosure relate to a method of preventing transmission of an enveloped RNA virus. The method includes applying to a mucosal tissue of a first mammalian subject not substantially colonized by the enveloped RNA virus an effective amount of an antiseptic composition or a pharmaceutically acceptable salt thereof according to a treatment plan. The first mammalian subject not substantially colonized by the enveloped RNA virus interacts with a second mammalian subject colonized by the enveloped RNA virus at a first viral load, the first mammalian subject has a second viral load based on the interaction, the second viral load is no greater than 0.5 log increase over an initial viral load over a duration of the treatment plan. The mucosal tissue is in the nasopharynx, nasal cavity, or anterior nares of the mammalian subject. The antiseptic composition comprises iodine, iodophor, or combinations thereof.
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公开(公告)号：US20220079893A1
公开(公告)日：2022-03-17
申请号：US17418718
申请日：2019-12-23
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Rajan B. Bodkhe , Ranjani V. Parthasarathy , Matthew T. Scholz , Naimul Karim , Petra L. Kohler Riedi , Joseph J Stoffel
Abstract: Compositions including a quaternary amine antiseptic component having a concentration of at least about 0.04% by weight; a poly carboxylic acid chelator having a concentration of at least about 0.05 M and/or an alphahydroxy acid buffer having a concentration of at least about 0.05 M; a (C8-C12) 1,2 alkane diol; and optionally water are provided. The compositions have a pH greater than or equal to 3.5 and less than 5.5 at 23° C. In certain embodiments, water is present in the composition at a greater weight percent than each of the quaternary amine antiseptic component; the polycarboxylic acid chelator, if present; the alphahydroxy acid buffer, if present; and the (C8-C12) 1,2-alkane diol. In certain embodiments, water is present in the composition at a greater weight percent than any other component.
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Patent Agency Ranking
公开(公告)号：US20220030860A1
公开(公告)日：2022-02-03
申请号：US17263663
申请日：2019-08-05
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Petra L. Kohler Riedi , Jimmie R. Baran, Jr. , Jie Yang , Ranjani V. Parthasarathy
Abstract: A composition. The composition includes a compound of Formula (I) HOCH2—(═CHOH═)n—CH2NR1R2 (I) wherein R1 and R2 are independently selected from the group consisting of a hydrogen atom, an alkyl group, C(O)R3, and SO2R4, wherein at least one of R1 and R2 is C(O)R3 or SO2R4, R3 and R4 are selected from the group consisting of an alkyl group having seven carbon atoms, an alkyl group having eight carbon atoms, and an alkyl group having nine carbon atoms, and n is an integer from about 2 to about wherein a concentration of the compound of Formula (I) is more than its critical micelle concentration; and an antimicrobial agent selected from the group consisting of a biguanide antimicrobial agent and a polymeric, cationic, non-micelle forming antimicrobial material; wherein a concentration of the antimicrobial agent is no more than 5 wt %.
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公开(公告)号：US10792383B2
公开(公告)日：2020-10-06
申请号：US16096776
申请日：2017-04-25
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Naiyong Jing , Ryan T. Woldt , Wensheng Xia , Kevin D. Landgrebe , Timothy J. Nies , Bryan A. Baker , Semra Colak Atan , Gary W. Jorgensen , Giuseppe M. Bommarito , David P. Swanson , George W. Griesgraber , Ranjani V. Parthasarathy
IPC: A61L2/00 , A61L9/00 , B08B7/00 , B08B9/04 , A61L2/18 , A61L2/28 , A01N35/02 , A01N33/02 , C12Q1/22
Abstract: A method of disinfecting a medical device comprises three steps. First, a disinfectant is contacted with a process indicator and the medical device. The disinfectant comprises at least one aldehyde. The process indicator contains a synthetic amine-containing compound disposed on a substrate. The synthetic amine-containing compound comprises at least one of primary amino groups or secondary amino groups, and is reactive with the disinfectant to form at least one adduct. The synthetic amine-containing compound and the medical device are in fluid communication through the disinfectant. A predetermined disinfectant exposure criterion exists for contacting the disinfectant with the medical device. Second, the process indicator is spectrally observed and at least one parameter is obtained therefrom that is predictive of the predetermined disinfectant exposure criterion. The third step is determining that the predetermined disinfectant exposure criterion has been achieved.
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公开(公告)号：US10342628B2
公开(公告)日：2019-07-09
申请号：US14428663
申请日：2013-09-20
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Matthew T. Scholz , Nicholas R. Powley , Ranjani V. Parthasarathy
Abstract: Surgical incise drapes including incision edge protectors are described. Methods of protecting the exposed edges of a surgical incision are also discussed.
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公开(公告)号：US20180360728A1
公开(公告)日：2018-12-20
申请号：US15736853
申请日：2016-06-27
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Ranjani V. Parthasarathy , Ramesh C. Kumar , Matthew T. Scholz , Steven P. Swanson , Erin A. Satterwhite
IPC: A61K8/81 , A61Q17/00 , A61K8/34 , A01N25/10 , A01N31/02 , A01N37/02 , A01N33/12 , A61K8/41 , A61K8/49 , A01N43/40 , A01N47/44 , A61K8/43 , A61L2/00
CPC classification number: A61K8/8152 , A01N25/10 , A01N31/02 , A01N33/12 , A01N37/02 , A01N43/40 , A01N47/44 , A61K8/0241 , A61K8/34 , A61K8/416 , A61K8/43 , A61K8/4926 , A61K2800/412 , A61L2/0088 , A61Q17/005
Abstract: Disclosed herein are compositions that include at least about 85 wt % of a hydroalcoholic solution that includes at least about 1 wt % water; and about 30 to about 85 wt % of at least one C1 to C4 alkyl alcohol based on the total weight of the hydroalcoholic solution; and acrylate copolymer particles dispersed in the hydroalcoholic solution, the acrylate copolymers particles being the reaction product of a reaction mixture, the reaction mixture including monomers, the monomers including from about 5 wt % to about 50 wt % of at least one high Tg monomer; and from about 20 w% to about 80 wt % of at least one low Tg monomer where the wt % of the low and high Tg monomers are with respect to the total weight of the monomers in the reaction mixture, wherein the particles have a number average diameter of at least about 100 nm.
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公开(公告)号：US09320834B2
公开(公告)日：2016-04-26
申请号：US14412808
申请日：2013-07-02
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor： Ranjani V. Parthasarathy , John M. Heapy , Vinod P. Menon , Matthew T. Scholz
CPC classification number: A61L31/048 , A01N25/10 , A61L31/141 , A61L31/143 , A61L31/16 , A61L2300/404 , A61L2300/602 , A61L2300/802 , C08K5/0016 , C08K5/0058 , C08K5/0066 , C08K5/19 , C08L27/06 , A01N33/12 , A01N47/44
Abstract: The present disclosure provides antimicrobial compositions including a polyhaloolefin polymer, a cationic antimicrobial agent, and a vehicle that includes a plasticizer and a heat stabilizer. The cationic antimicrobial agent can be partially soluble in the vehicle. The present disclosure also provides for articles formed from the composition, with cationic antimicrobial agent incorporated throughout the polymer matrix, as well as methods of manufacturing the composition.
Abstract translation: 本公开提供了包含聚卤代烯烃聚合物，阳离子抗微生物剂和包含增塑剂和热稳定剂的载体的抗微生物组合物。 阳离子抗微生物剂可以局部溶于载体。 本公开还提供了由组合物形成的制品，并且整个聚合物基质中并入阳离子抗微生物剂，以及制备组合物的方法。
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