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公开(公告)号：US10143572B2
公开(公告)日：2018-12-04
申请号：US14121435
申请日：2014-09-04
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Richard Rapoza , Susan Veldhof , James Oberhauser , Syed F. A. Hossainy
Abstract: A method of treating vascular disease in a patient is disclosed that comprises deploying a bioabsorbable polymer scaffold composed of a plurality of struts at a stenotic segment of an artery of a patient, wherein after the scaffold supports the segment at an increased diameter for a period of time the polymer degrades and is progressively replaced by de novo formation of malleable provisional matrix comprising proteoglycan, wherein as the scaffold becomes more malleable and becomes disconnected as it degrades, wherein following coverage of the struts by a neointima layer and loss of mechanical support provided by the scaffold, the scaffold is pulled outward by positive remodeling of the vessel wall of the scaffolded segment.
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公开(公告)号：US09687594B2
公开(公告)日：2017-06-27
申请号：US14970890
申请日：2015-12-16
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yunbing Wang , Xiao Ma , James Oberhauser
IPC: A61F2/06 , A61L31/14 , A61L31/06 , C08G63/08 , C08G63/90 , A61F2/89 , A61F2/82 , C08L67/04 , C09J167/04 , A61K9/20 , C09D167/04 , A61K9/16 , A61F2/958 , A61F2/30
CPC classification number: A61L31/148 , A61F2/82 , A61F2/89 , A61F2/958 , A61F2002/30062 , A61F2210/0004 , A61K9/1647 , A61K9/204 , A61L31/06 , B29C47/0066 , B29K2067/046 , B29L2031/7534 , C08G63/08 , C08G63/90 , C08J2367/04 , C08L67/04 , C09D167/04 , C09J167/04
Abstract: Methods of treating with a biodegradable polymeric stent made from poly(L-lactide) and a low concentration of L-lactide monomer is disclosed. The concentration of L-lactide is adjusted to provide a degradation behavior that is suitable for different treatment applications including coronary, peripheral, and nasal.
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23.发明申请BRANCHED POLYHYDROXYALKANOATE SYSTEMS FOR BIORESORBABLE VASCULAR SCAFFOLD APPLICATIONS 审中-公开用于生物可溶性血管松弛应用的分支聚羟基烷酸盐系统公开(公告)号：US20150305899A1
公开(公告)日：2015-10-29
申请号：US14261358
申请日：2014-04-24
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Joel E. Harrington , Mary Beth Kossuth , James Oberhauser
IPC: A61F2/856
CPC classification number: A61F2/915 , A61F2/958 , A61F2002/91575 , A61L31/06 , C08L67/04
Abstract: An implantable medical devices such as a stent that includes sparse comb polyhydroxyalkanoate (PHA) systems is disclosed. The stent includes a stent body, scaffold, or substrate made partially or completely of polymer material including PHA.
Abstract translation: 公开了一种植入式医疗装置，例如包括稀疏梳聚羟基链烷酸酯（PHA）系统的支架。 支架包括支架主体，支架或由部分或完全由包括PHA的聚合物材料制成的基底。
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24.发明授权Controlling moisture in and plasticization of bioresorbable polymer for melt processing 有权控制生物可吸收聚合物的水分和塑化，用于熔体加工公开(公告)号：US09168677B2
公开(公告)日：2015-10-27
申请号：US14311175
申请日：2014-06-20
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Bethany Steichen , Stephen Pacetti , Manish Gada , Thierry Glauser , Lothar Kleiner , Yunbing Wang , James Oberhauser , Ni Ding
CPC classification number: B29C47/0078 , B29B13/06 , B29B13/065 , B29C47/0014 , B29C47/0021 , B29C47/0023 , B29C47/1018 , B29C47/1072 , B29C47/76 , B29C47/92 , B29C2947/922 , B29C2947/92228 , B29C2947/92342 , B29C2947/92695 , B29C2947/92704 , B29C2947/92723 , B29K2995/006
Abstract: Methods and systems for controlling the moisture content of biodegradable and bioresorbable polymer resin during extrusion above a lower limit that allows for plasticization of the polymer resin melt and below an upper limit to reduce or prevent molecular weight loss are disclosed. Methods are further disclosed involving plasticization of a polymer resin for feeding into an extruder with carbon dioxide and freon.
Abstract translation: 公开了用于在挤出之前控制可生物降解和生物可再吸收的聚合物树脂的含水量的方法和系统，其允许聚合物树脂熔体增塑并低于上限以降低或防止分子量损失。 进一步公开的方法涉及用二氧化碳和氟利昂进料到挤出机中的聚合物树脂的增塑。
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公开(公告)号：US20140114394A1
公开(公告)日：2014-04-24
申请号：US13998204
申请日：2013-10-09
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： David C. Gale , Bin Huang , Timothy A. Limon , Vincent J. Gueriguian , Anthony J. Abbate , Klaus Kleine , Stephen Schaible , Jonathan P. Durcan , Thierry Glauser , Bethany Steichen , James Oberhauser , Manish Gada , Lothar Kleiner , Mary Beth Kossuth , Yunbing Wang , Daniel Castro , David Wrolstad
IPC: A61F2/82
CPC classification number: A61F2/915 , A61F2002/9522 , A61F2210/0004 , A61F2240/001 , A61F2250/0067 , A61L31/06 , A61L31/14 , B29C35/045 , B29C49/0005 , B29C49/14 , B29C49/4823 , B29C55/24 , B29C69/001 , B29C2049/0089 , B29C2793/0009 , B29K2067/00 , B29K2067/046 , B29K2105/258 , B29K2995/006 , B29L2031/7534 , C08L67/04
Abstract: Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed.
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Patent Agency Ranking
公开(公告)号：US20140107761A1
公开(公告)日：2014-04-17
申请号：US13998194
申请日：2013-10-09
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： David C. Gale , Bin Huang , Timothy A. Limon , Vincent J. Gueriguian , Anthony J. Abbate , Klaus Kleine , Stephen Schaible , Jonathan P. Durcan , Thierry Glauser , Bethany Steichen , James Oberhauser , Manish Gada , Lothar Kleiner , Mary Beth Kossuth , Yunbing Wang , Daniel Castro , David Wrolstad
IPC: A61F2/82
CPC classification number: A61F2/90 , A61F2/82 , A61F2/91 , A61F2/915 , A61F2002/91533 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575 , A61F2002/9522 , A61L31/06 , A61L31/14 , B29C35/045 , B29C49/0005 , B29C49/14 , B29C49/4823 , B29C55/24 , B29C69/001 , B29C2049/0089 , B29C2793/0009 , B29K2067/00 , B29K2067/046 , B29K2105/258 , B29K2995/006 , B29L2031/7534 , C08L67/04
Abstract: Stents and methods of manufacturing a stents with enhanced fracture toughness are disclosed.
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公开(公告)号：US09844612B2
公开(公告)日：2017-12-19
申请号：US15597962
申请日：2017-05-17
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yunbing Wang , Xiao Ma , James Oberhauser
IPC: A61L31/14 , A61L31/06 , C08G63/08 , C08G63/90 , A61F2/89 , A61F2/82 , C08L67/04 , A61F2/30 , C09J167/04 , A61K9/20 , C09D167/04 , A61K9/16 , A61F2/958 , B29L31/00 , B29C47/00 , B29K67/00
CPC classification number: A61L31/148 , A61F2/82 , A61F2/89 , A61F2/958 , A61F2002/30062 , A61F2210/0004 , A61K9/1647 , A61K9/204 , A61L31/06 , B29C47/0066 , B29K2067/046 , B29L2031/7534 , C08G63/08 , C08G63/90 , C08J2367/04 , C08L67/04 , C09D167/04 , C09J167/04
Abstract: Methods of treating with a biodegradable polymeric stent made from poly(L-lactide) and a low concentration of L-lactide monomer is disclosed. The concentration of L-lactide is adjusted to provide a degradation behavior that is suitable for different treatment applications including coronary, peripheral, and nasal.
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公开(公告)号：US09498321B2
公开(公告)日：2016-11-22
申请号：US15042045
申请日：2016-02-11
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yunbing Wang , James Oberhauser , Manish Gada
CPC classification number: A61F2/06 , A61L31/041 , A61L31/129 , A61L31/148 , A61L31/16 , A61L2300/422 , C08L67/04
Abstract: A medical device implantable within a peripheral vessel of the body composed of a bioresorbable polymer is disclosed. The device has a high resistance to fracture, is very flexible, and has a high crush recovery when subjected to crushing, axial, or torsional forces.
Abstract translation: 公开了一种可植入在由生物可再吸收的聚合物组成的身体的外周血管内的医疗装置。 该装置具有高抗断裂性，非常柔软，并且当受到破碎，轴向或扭转力时具有高的压碎恢复性。
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公开(公告)号：US09277983B2
公开(公告)日：2016-03-08
申请号：US13802098
申请日：2013-03-13
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yunbing Wang , James Oberhauser , Manish Gada
CPC classification number: A61F2/06 , A61L31/041 , A61L31/129 , A61L31/148 , A61L31/16 , A61L2300/422 , C08L67/04
Abstract: A medical device implantable within a peripheral vessel of the body composed of a bioresorbable polymer is disclosed. The device has a high resistance to fracture, is very flexible, and has a high crush recovery when subjected to crushing, axial, or torsional forces.
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公开(公告)号：US09211682B2
公开(公告)日：2015-12-15
申请号：US13734879
申请日：2013-01-04
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Thierry Glauser , Vincent Gueriguian , Bethany Steichen , James Oberhauser , Manish Gada , Lothar Kleiner , Mary Beth Kossuth
IPC: B29C55/26 , B29C35/00 , B29D22/00 , B29C49/08 , B29C49/02 , A61F2/91 , B29C49/00 , B29C49/04 , B29C49/78 , B29L31/00
CPC classification number: B29D22/00 , A61F2/91 , B29C49/0005 , B29C49/02 , B29C49/04 , B29C49/08 , B29C49/78 , B29C55/26 , B29C2793/009 , B29K2995/004 , B29K2995/0041 , B29K2995/0046 , B29K2995/0056 , B29K2995/006 , B29K2995/0077 , B29K2995/0089 , B29L2031/7542
Abstract: Methods to expand polymer tubing with desirable or optimum morphology and mechanical properties for stem manufacture and fabrication of a stent therefrom are disclosed.
Abstract translation: 公开了扩展聚合物管的方法，其具有用于茎的制造和制造支架的所需或最佳形态和机械性能。
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