-
公开(公告)号：US20180093020A1
公开(公告)日：2018-04-05
申请号：US15832450
申请日：2017-12-05
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Lothar W. Kleiner , Syed F.A. Hossainy , Mikael Trollsas , Stephen D. Pacetti
CPC classification number: A61L31/148 , A61L31/10 , A61L31/16 , A61L2300/41 , A61L2300/416 , A61L2300/42 , A61L2420/02 , A61L2420/08 , C08L67/04
Abstract: The present invention provides an absorbable coating for an implantable device and the methods of making and using the same.
-
22.发明授权公开(公告)号：US09592323B2
公开(公告)日：2017-03-14
申请号：US14109795
申请日：2013-12-17
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Florencia Lim , Mikael O. Trollsas , Syed F.A. Hossainy , Stephen D. Pacetti
CPC classification number: A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/604 , A61L2300/606 , Y10T24/258 , C08L67/04
Abstract: The present invention provides a coating comprising a reservoir layer comprising a semi-crystalline polymer and a primer layer comprising an amorphous polymer on an implantable device and methods of making and using the same.
Abstract translation: 本发明提供一种包含储存层的涂层，其包含半结晶聚合物和在可植入装置上包含无定形聚合物的底漆层及其制备和使用该涂层的方法。
-
公开(公告)号：US20150297380A1
公开(公告)日：2015-10-22
申请号：US14687843
申请日：2015-04-15
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Benjamyn Serna , Michael Huy Ngo , Syed F.A. Hossainy , O. Mikael Trollsas
CPC classification number: A61F2/95 , A61F2210/0076 , A61F2230/0063 , A61F2240/001 , A61F2250/0067 , A61L2420/02 , B05D1/002 , B05D1/38 , B05D3/10 , B05D3/12
Abstract: Embodiments of the present invention encompass methods of forming coatings, particularly coatings for medical devices, and more particularly, for braided or woven medical devices. Embodiments of the present invention encompass the coatings and the coated devices. The coatings may include a polymer and optionally a therapeutic agent.
Abstract translation: 本发明的实施例包括形成涂层的方法，特别是用于医疗装置的涂层，更具体地，涉及编织或编织的医疗装置。 本发明的实施例包括涂层和涂覆装置。 涂层可以包括聚合物和任选的治疗剂。
-
公开(公告)号：US20140212476A1
公开(公告)日：2014-07-31
申请号：US14227589
申请日：2014-03-27
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Dariush Davalian , John Stankus , Yuet Mei Khong , O. Mikael Trollsas , Syed F.A. Hossainy
IPC: A61K9/127 , A61K31/439 , A61K47/48 , A61K41/00
CPC classification number: A61K9/127 , A61K9/107 , A61K9/1273 , A61K31/439 , A61K47/6911
Abstract: This invention relates to the targeted delivery of hydrophobic drugs or combinations of hydrophobic drugs with photodynamic therapy agents to vascular lesions by complexation of the drugs to blood serum lipoproteins, which have an affinity for and accumulate in such vascular lesions.
Abstract translation: 本发明涉及疏水性药物或疏水性药物与光动力治疗剂的组合的靶向递送，其通过使药物与血清脂蛋白的复合而形成，所述血清脂蛋白与这种血管病变具有亲和力并且积聚在血管损伤中。
-
公开(公告)号：US20140037831A1
公开(公告)日：2014-02-06
申请号：US14051214
申请日：2013-10-10
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Florian N. Ludwig , Syed F.A. Hossainy , Srinivasan Sridharan , Carol Lee
IPC: A61L31/10
CPC classification number: A61L31/10 , A61L27/34 , A61L27/50 , A61L27/54 , A61L2300/406 , A61L2300/41 , A61L2300/416 , A61L2300/606 , A61M31/002
Abstract: Methods are disclosed for controlling the morphology and the release-rate of active agent from coating layers for medical devices comprising a polymer matrix and one or more active agents. The methods comprise fixing the morphology or phase distribution of the active agent prior to removing solvent from the coating composition. The coating layers can be used for controlled the delivery of an active agent or a combination of active agents.
Abstract translation: 公开了用于控制活性剂从包含聚合物基质和一种或多种活性剂的医疗装置的涂层的形态和释放速率的方法。 所述方法包括在从涂料组合物除去溶剂之前固定活性剂的形态或相分布。 涂层可用于控制活性剂或活性剂的组合的递送。
-
Patent Agency Ranking
26.发明申请Methods of treatment of polymeric coatings for control of agent release rates 审中-公开处理聚合物涂层以控制药剂释放速率的方法公开(公告)号：US20140004250A1
公开(公告)日：2014-01-02
申请号：US13953656
申请日：2013-07-29
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed F.A. Hossainy , Fuh-Wei Tang , Lothar W. Kleiner , Thierry Glauser , Yiwen Tang , Wouter E. Roorda , Stephen D. Pacetti , Gina Zhang , Yung-Ming Chen , Andrew F. McNiven , Sean A. McNiven , Brandon J. Yoe
IPC: A61L31/10
CPC classification number: A61L31/10 , A61L27/40 , A61L27/44 , A61L27/50 , A61L27/54 , A61L31/12 , A61L31/14 , A61L31/16 , A61L2300/00
Abstract: The present disclosure teaches methods of controlling the release rate of agents from a polymeric matrix that include designing and creating a predetermined initial morphology (IM) profile in a polymeric matrix. The teachings indicate, inter alia, that control over the release rate of agents can provide for an improved control over the administration of agents as well as have an effect upon the mechanical integrity and absorption rate of the polymeric matrix.
Abstract translation: 本公开教导了控制来自聚合物基质的试剂的释放速率的方法，其包括在聚合物基质中设计和产生预定的初始形态（IM）分布。 教导尤其表明，对药剂释放速率的控制可以提供对药剂施用的改进控制，以及对聚合物基质的机械完整性和吸收速率的影响。
-
公开(公告)号：US20130273234A1
公开(公告)日：2013-10-17
申请号：US13911572
申请日：2013-06-06
Applicant: Abbott Cardiovascular Systems, Inc.
Inventor： Syed F.A. Hossainy
IPC: A61L31/10
CPC classification number: A61L31/16 , A61K31/445 , A61K31/74 , A61L31/10 , C08L33/06
Abstract: A composition comprising a structural component comprising linear acrylic homopolymers or linear acrylic copolymers and a biobeneficial component comprising copolymers having an acrylate moiety and a biobeneficial moiety is disclosed. A medical article comprising the composition in the coating thereof and a method of fabricating the medical article are also disclosed.
-
公开(公告)号：US20170049593A1
公开(公告)日：2017-02-23
申请号：US14832283
申请日：2015-08-21
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed F.A. Hossainy , Manish B. Gada
CPC classification number: B29C69/001 , A61F2/915 , A61F2002/91533 , A61F2002/91558 , A61F2210/0004 , A61F2210/0071 , A61F2240/001 , B29C55/26 , B29K2067/046 , B29K2995/004 , B29K2995/0056 , B29K2995/0077 , B29K2995/0088 , B29K2995/0097 , B29L2031/7534
Abstract: Methods of fabricating a polymer scaffold with increased radial strength including steps of elongation or strain of a biaxially oriented tube and annealing or thermal processing of the strained tube at a constant strain are disclosed. The steps of elongation and thermal processing increase axial direction chain orientation and lamellar crystal growth, increase radial strength, and decrease the thickness of the tube. The method allows fabrication of a scaffold with thinner struts which provide sufficient radial strength.
Abstract translation: 公开了制备具有增加的径向强度的聚合物支架的方法，包括双轴取向管的伸长或应变步骤以及在恒定应变下对应变管的退火或热加工。 伸长和热处理的步骤增加轴向链取向和层状晶体生长，增加径向强度，并减小管的厚度。 该方法允许制造具有较薄支柱的支架，其提供足够的径向强度。
-
公开(公告)号：US20160052200A1
公开(公告)日：2016-02-25
申请号：US14928823
申请日：2015-10-30
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Yung-Ming Chen , Jason Van Sciver , Syed F.A. Hossainy , Stephen Pacetti
CPC classification number: B29C65/76 , A61F2/82 , A61F2/86 , A61F2/91 , A61F2210/0004 , A61F2210/0076 , A61F2240/001 , A61F2250/0067 , A61F2310/00389 , A61L31/14 , A61L31/148 , A61L2420/02 , B05D1/38 , B05D3/0254 , B05D3/0473 , B29C65/10 , B29K2067/046 , B29K2105/258 , B29L2031/7534
Abstract: Various embodiments of methods for coating stents are described herein. Applying a composition including polymer component and solvent to a stent substrate followed by exposing the polymer component to a temperature equal to or greater than a Tg of the polymer component is disclosed. Repeating the applying and exposing one or more times to form a coating with the result that the solvent content of the coating after the final exposing step is at a level suitable for a finished stent is further disclosed.
-
30.发明申请PLASTICIZERS FOR A BIODEGRADABLE SCAFFOLDING AND METHODS OF FORMING SAME 有权用于生物可降解SCAFFING的塑化剂及其形成方法公开(公告)号：US20150359947A1
公开(公告)日：2015-12-17
申请号：US14304792
申请日：2014-06-13
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed F.A. Hossainy , Stephen D. Pacetti
CPC classification number: A61L31/141 , A61L31/06 , A61L31/148 , A61L2400/00 , B29C45/0053 , B29C45/72 , B29C71/0009 , B29C71/02 , B29C2071/0027 , B29C2071/022 , B29K2033/04 , B29K2067/04 , B29L2031/753 , C08J3/18 , C08J9/00 , C08J2207/10 , C08J2300/16 , C08K5/0016
Abstract: Methods of making polymeric devices, such as stents, with one or more modifications such as addition of plasticizers, to improve processing, and the devices made by these methods.
Abstract translation: 制备聚合物装置（例如支架）的方法，具有一种或多种改性，例如添加增塑剂以改善加工，以及通过这些方法制备的装置。
-
-
-
-
-
-
-
-
-
Search Results
37
records
(took 0.024 seconds)
