公开(公告)号：US08858486B2

公开(公告)日：2014-10-14

申请号：US12744281

申请日：2008-11-22

申请人： Wei Zhang ,  Elke Schulte ,  Christoph Bardorz

发明人： Wei Zhang ,  Elke Schulte ,  Christoph Bardorz

IPC分类号： A61M37/00 ,  A61M1/36 ,  A61M1/16

CPC分类号： A61M1/16 ,  A61M1/1617 ,  A61M1/3658 ,  A61M2205/13

摘要： A method for determining the recirculation in a fistula and/or the cardiopulmonary recirculation part during an extracorporeal blood treatment is disclosed, where the blood to be treated flows in an extracorporeal blood circuit through a blood chamber of a dialyzer split by a semi-permeable membrane into the blood chamber and a liquid chamber, and dialysis liquid flows in a dialysis liquid path through the dialysis liquid chamber of the dialyzer. A device for determining the recirculation in a fistula and/or the cardiopulmonary recirculation part, and a blood treatment device including such a device are also disclosed. The method and device are based on the fact that the sum of the fistula recirculation and the cardiopulmonary recirculation part, i.e. the total recirculation, is determined for two blood flow rates which differ from each other. The fistula recirculation and/or the cardiopulmonary recirculation part are then determined from the recirculation for the two blood flow rates.

摘要翻译： 公开了一种用于在体外血液处理期间确定瘘管和/或心肺再循环部分中的再循环的方法，其中待治疗的血液通过半透膜分离的透析器的血室在体外血液回路中流动 进入血液室和液体室，并且透析液体在透析液体路径中流过透析器的透析液体室。 还公开了一种用于确定瘘管和/或心肺再循环部分中的再循环的装置，以及包括这种装置的血液处理装置。 该方法和装置基于以下事实：对于彼此不同的两个血液流速，确定瘘再循环和心肺再循环部分的总和，即总再循环。 然后从两次血流速率的再循环中确定瘘再循环和/或心肺再循环部分。

公开(公告)号：US08847084B2

公开(公告)日：2014-09-30

申请号：US13634699

申请日：2011-03-08

申请人： Wei Zhang ,  Masashi Kawamata ,  Tatsushi Yamaguchi ,  Daigorou Shiozawa

发明人： Wei Zhang ,  Masashi Kawamata ,  Tatsushi Yamaguchi ,  Daigorou Shiozawa

IPC分类号： H05K7/14 ,  H02B13/035 ,  G01R15/24 ,  H02G5/06

CPC分类号： G01R15/246 ,  H02B13/0356 ,  H02G5/066

摘要： Insulating spacer 1 has insulating molded member 3 molded as a single body with insulating material such as epoxy resin, in which at least one electric conductor 2, a grounding shield surrounding the electric conductor(s), and Optical fiber 14 of Faraday-effect element are embedded to form a build-in configuration. The grounding shield can be formed of cylindrical shielding member 15 made of metal wires, metal strips, or a cylindrical metallic member having a perforation of a plurality of small holes thereon. The aforementioned optical fiber 14, which is to be used as a component of an optical current transformer, is put in a certain place in cylindrical shielding member 15.

摘要翻译： 绝缘间隔件1具有用诸如环氧树脂的绝缘材料作为单体模制的绝缘模制构件3，其中至少一个电导体2，围绕导电体的接地屏蔽以及法拉第效应元件的光纤14 被嵌入以形成内置配置。 接地屏蔽可以由金属线，金属带或其上具有多个小孔的穿孔的圆柱形金属构件制成的圆柱形屏蔽构件15形成。 将要用作光电流互感器的组件的上述光纤14放置在圆筒形屏蔽构件15中的某个位置。

公开(公告)号：US08815997B2

公开(公告)日：2014-08-26

申请号：US13453057

申请日：2012-04-23

申请人： Wei Zhang ,  Ozzie M. Pressley ,  Monica A. Luckenbach ,  James C. Bohling

发明人： Wei Zhang ,  Ozzie M. Pressley ,  Monica A. Luckenbach ,  James C. Bohling

IPC分类号： C08L31/00 ,  C08J5/20

CPC分类号： C09D5/002 ,  C09D5/022 ,  C09D5/1637 ,  C09D7/65 ,  C09D143/02

摘要： The present invention provides one component aqueous compositions comprising (i) from 0.01 to 7 wt. %, based on the total weight of solids in the composition, of anion exchange resin beads having a weight average particle size of from 0.1 to 20 μm a low crosslinker content, the anion exchange resin copolymer beads being chosen from gelular beads, beads having a dual morphology, and mixtures thereof, (ii) an emulsion copolymer having a copolymerization residue of one or more phosphorus acid monomer, and having an anionic surfactant or its polymerization residue and a reductant or its polymerization residue and, (iii) at least one phosphorous containing surfactant in the amount of from 0.1 to 5 wt. %, based on the weight of emulsion copolymer solids. The compositions find use as coating binders and either pigmented or unpigmented paints and enable the provision of a single coat primer plus topcoat with excellent stain blocking.

摘要翻译： 本发明提供单组分水性组合物，其包含（i）0.01至7重量％ ％，基于组合物中固体的总重量，具有低交联剂含量的重均粒径为0.1至20μm的阴离子交换树脂珠，阴离子交换树脂共聚物珠选自凝胶珠，具有 双重形态及其混合物，（ii）具有一个或多个磷酸单体的共聚残基并具有阴离子表面活性剂或其聚合残基和还原剂或其聚合残基的乳液共聚物，和（iii）至少一种磷 含量为0.1-5重量％的表面活性剂。 ％，基于乳液共聚物固体的重量。 该组合物用作涂料粘合剂和着色或未着色的涂料，并且能够提供具有优异污渍阻挡性能的单一涂料底漆和外涂层。

公开(公告)号：US08792089B2

公开(公告)日：2014-07-29

申请号：US13554145

申请日：2012-07-20

申请人： Wei Zhang ,  Elke Schulte ,  Martin Kaiser ,  Carsten Mueller ,  Tom Klein ,  Stefan Zerle ,  Christoph Bardorz ,  Stefan Stuehler

发明人： Wei Zhang ,  Elke Schulte ,  Martin Kaiser ,  Carsten Mueller ,  Tom Klein ,  Stefan Zerle ,  Christoph Bardorz ,  Stefan Stuehler

IPC分类号： G01N33/48

CPC分类号： G01N33/49 ,  A61B5/14557 ,  A61M1/367 ,  A61M2205/14 ,  A61M2205/3306 ,  A61M2230/20 ,  G01N21/05 ,  G01N21/31 ,  G01N2021/0378 ,  G01N2021/3144

摘要： A device for determining the concentration of a constituent of blood in a hose line, in particular in the hose line of an extracorporeal blood circuit of an extracorporeal blood treatment apparatus, includes a clamping unit having an actuation mechanism configured to apply a clamping force such that first and second receiving elements are moved towards one another from a first position releasing the hose line into a second position clamping the hose line, in which the drive of the actuation mechanism takes place with an electric motor, and a monitoring unit configured to detect a hose line inserted into the receiving elements. A method for detecting a hose line in a clamping unit of a device for determining the concentration of a blood constituent in the hose line is also described. Automation of the measurement of the blood parameters is thus possible.

摘要翻译： 一种用于确定软管管线中的血液成分浓度的装置，特别是在体外血液处理设备的体外血液回路的软管管线中的装置，包括具有致动机构的夹紧单元，该致动机构构造成施加夹紧力，使得 第一和第二接收元件从第一位置朝向彼此移动，从而将软管线释放到夹紧软管线的第二位置，其中致动机构的驱动通过电动机进行，以及监视单元，其被配置为检测 软管线插入接收元件。 还描述了用于检测用于确定软管管线中的血液成分浓度的装置的夹持单元中的软管线的方法。 因此血液参数测量的自动化是可能的。

公开(公告)号：US20140162945A1

公开(公告)日：2014-06-12

申请号：US14125061

申请日：2012-06-08

申请人： Tao Ma ,  Shusen Xu ,  Zhijun Liu ,  Bo Zhang ,  Ning Shen ,  Hai Yang ,  Wei Zhang ,  Yuhua Li ,  Sunghwan Moon ,  Maengsup Kim

发明人： Tao Ma ,  Shusen Xu ,  Zhijun Liu ,  Bo Zhang ,  Ning Shen ,  Hai Yang ,  Wei Zhang ,  Yuhua Li ,  Sunghwan Moon ,  Maengsup Kim

IPC分类号： C07K14/575

CPC分类号： C07K14/575 ,  A61K38/00 ,  A61K38/16 ,  A61K38/22 ,  C07K14/00 ,  C07K14/605

摘要： The present invention provides a GIP analog, which is derived from GIP (1-29, SEQ ID NO: 1), has both GLP-1 agonist activity and GIPR stimulation activity, and comprises an amino acid sequence represented by the following formula I: Tyr-A2-A3-Gly-Thr-Phe-A7-Ser-Asp-Tyr-Ser-A12-A13-A14-A15-Lys-A17-A18-A19-A20-A21-A22-A23-A24-Trp-Leu-A27-A28-A29-Y. The present invention also provides a pharmaceutical composition comprising the GIP analog and use thereof.

摘要翻译： 本发明提供衍生自GIP（1-29，SEQ ID NO：1）的GIP类似物具有GLP-1激动剂活性和GIPR刺激活性，并且包含由下式I表示的氨基酸序列： Tyr-A2-A3-Gly-Thr-Phe-A7-Ser-Asp-Tyr-Ser-A12-A13-A14-A15-Lys-A17-A18-A19-A20-A21-A22-A23-A24-Trp- Leu-A27-A28-A29-Y。 本发明还提供了包含GIP类似物及其用途的药物组合物。

公开(公告)号：US08722939B2

公开(公告)日：2014-05-13

申请号：US13504893

申请日：2010-10-29

申请人： Donald R. Kirsch ,  Radhia Benmohamed ,  Anthony C. Arvanites ,  Richard I. Morimoto ,  Wei Zhang ,  Richard B. Silverman

发明人： Donald R. Kirsch ,  Radhia Benmohamed ,  Anthony C. Arvanites ,  Richard I. Morimoto ,  Wei Zhang ,  Richard B. Silverman

IPC分类号： C07C49/697 ,  C07C225/22 ,  C07D295/205 ,  A61K31/136 ,  A61K31/495 ,  A61K31/403

CPC分类号： C07C69/75 ,  A61K31/136 ,  C07C49/563 ,  C07C49/567 ,  C07C49/577

摘要： The present invention relates to the identification of provided cyclohexane-1,3-diones (CHD compounds) and pharmaceutical compositions thereof for treating subjects with amyotrophic lateral sclerosis (ALS) and other neurodegenerative diseases. The invention also provides methods of preparing the provided CHD compounds.

摘要翻译： 本发明涉及提供的环己烷-1,3-二酮（CHD化合物）及其药物组合物的鉴定，用于治疗肌萎缩性侧索硬化（ALS）和其它神经变性疾病的受试者。 本发明还提供了制备所提供的CHD化合物的方法。

公开(公告)号：US20140070083A1

公开(公告)日：2014-03-13

申请号：US14117542

申请日：2011-05-24

申请人： Wei Zhang ,  Robert Atkinson ,  Michael T. Pelletier ,  Christopher M. Jones

发明人： Wei Zhang ,  Robert Atkinson ,  Michael T. Pelletier ,  Christopher M. Jones

IPC分类号： G01N21/25 ,  G02B26/00 ,  G01V8/00

CPC分类号： G01N21/255 ,  G01J3/0202 ,  G01J3/12 ,  G01J3/51 ,  G01J2003/1221 ,  G01V8/00 ,  G02B26/008

摘要： Downhole spectrometer tools are provided with two ways to increase the number of filters on an optical path. A first approach employs multiple filter wheels that rotate alternately in a common plane to intersect the optical path. Portions of the wheels are cut out to avoid mechanical interference between the wheels. A second approach drives the one or more filter wheels with a wobble that causes the filters to trace one or more hypocycloidal curves that each intersect the optical path.

摘要翻译： 井下光谱仪工具具有两种增加光路上滤光片数量的方法。 第一种方法采用在公共平面中交替旋转的多个滤光轮与光路相交。 切割车轮的部分以避免车轮之间的机械干扰。 第二种方法是驱动一个或多个过滤轮，其摆动使得过滤器跟踪一个或多个每个与光路相交的下摆曲线。

公开(公告)号：US08670386B2

公开(公告)日：2014-03-11

申请号：US13335999

申请日：2011-12-23

申请人： Wei Bai ,  Bingyu Qu ,  Sha Ma ,  Wei Jin ,  Yang Li ,  Wei Zhang

发明人： Wei Bai ,  Bingyu Qu ,  Sha Ma ,  Wei Jin ,  Yang Li ,  Wei Zhang

IPC分类号： H04W4/00

CPC分类号： H04L5/0053 ,  H04B7/2606 ,  H04L5/0007 ,  H04W16/10 ,  H04W16/26 ,  H04W72/042 ,  H04W84/047

摘要： The present invention discloses a method which includes: allocating, by an eNodeB, a dedicated resource region for a relay served by the eNodeB; calculating, by the eNodeB, a control channel of the relay; configuring, by the eNodeB according to the resource region allocated for the relay and the acquired control channel of the relay, the control channel of the relay in the resource region corresponding to the relay; and detecting, by the relay, control information sent by the eNodeB in the corresponding resource region allocated by the eNodeB for the relay. The present invention solves the transmission problem of a backhaul link control channel in an LTE-A relay system, so that a relay can receive control information sent by the eNodeB within a wider scope and that the complexity of blind detection of the relay is decreased.

摘要翻译： 本发明公开了一种方法，包括：由eNodeB分配由eNodeB服务的中继器的专用资源区域; 由eNodeB计算继电器的控制信道; 由eNodeB根据为中继分配的资源区域和所获取的中继控制信道，配置与继电器对应的资源区域中的中继控制信道; 以及由所述中继器检测所述eNodeB在由所述eNodeB为所述中继分配的对应资源区域中发送的控制信息。 本发明解决了LTE-A中继系统中的回程链路控制信道的传输问题，使得中继站能够在较宽的范围内接收由eNodeB发送的控制信息，并且降低了对继电器的盲检测的复杂度。

公开(公告)号：US20140027234A1

公开(公告)日：2014-01-30

申请号：US14008788

申请日：2012-03-30

申请人： Huasong Zhou ,  Wei Zhang ,  Jianmin Chen ,  Bin Cao

发明人： Huasong Zhou ,  Wei Zhang ,  Jianmin Chen ,  Bin Cao

IPC分类号： B05B1/16

CPC分类号： C07D239/47 ,  B05B1/1636 ,  B05B1/18 ,  C07D239/48 ,  C07D405/12 ,  C07D487/04

摘要： An auto-rebound switching apparatus has: a body provided with a water-separating apparatus, an upper cover rotatably arranged on the rear side of the body, a passive disc rotatably arranged between the rear side of the body and the upper cover, a clutch mechanism comprising a bi-directional ratchet gear and a bi-directional pawl matching the ratchet gear, the ratchet gear being rotatably arranged on the rear side of the body and transmissively connected to the water-separating apparatus, thus allowing the ratchet gear, when rotating, to drive the water-separating apparatus into motion to allow switching, the bi-directional pawl, the upper cover, and the passive disc being interconnected, allowing the upper cover to rotate relative to the passive disc thus driving the bi-directional pawl to move between a forward rotation position, a reverse rotation position, and a detached position, and a rebound apparatus.

摘要翻译： 一种自动回弹切换装置具有：主体，其具有水分离装置，可旋转地布置在主体后侧的上盖，可旋转地布置在主体的后侧和上盖之间的无源盘，离合器 机构包括双向棘轮齿轮和与棘轮相配合的双向棘爪，该棘轮齿轮可旋转地布置在主体的后侧上，并透射连接到水分离装置，从而允许棘轮在旋转时 ，以驱动水分离装置运动以允许切换，双向棘爪，上盖和无源盘互连，允许上盖相对于无源盘旋转，从而将双向棘爪驱动到 在正向旋转位置，反向旋转位置和分离位置之间移动，以及回弹装置。

公开(公告)号：US08632720B2

公开(公告)日：2014-01-21

申请号：US12794971

申请日：2010-06-07

申请人： Wei Zhang ,  Hua Tan ,  Stephen Y. Chou

发明人： Wei Zhang ,  Hua Tan ,  Stephen Y. Chou

IPC分类号： B29C33/46 ,  B29C37/00

CPC分类号： B29C37/0053 ,  B29C33/10 ,  B29C33/46 ,  B29C37/006 ,  B29C2035/0827 ,  B29C2059/023 ,  B82Y10/00 ,  B82Y40/00 ,  G03F7/0002

摘要： A mold for imprinting a patterned region by imprint lithography is provided with a peripheral groove around the patterned region. The groove is connected, as by channels through the mold, to a switchable source for gas removal to prevent bubbles and for the application of pressurized gas to separate the mold and substrate. In use, the mold is disposed adjacent the moldable surface and gas is withdrawn from the patterned region through the groove as the mold is pressed toward and into the moldable surface. At or near the end of the imprinting, the process is switched from removal of gas to the application of pressurized gas. The pressurized gas passes through the groove and separates or facilitates separation of the mold and the moldable surface.

摘要翻译： 用于通过压印光刻压印图案化区域的模具在图案化区域周围设置有周边凹槽。 凹槽通过通过模具的通道连接到用于气体去除的可切换源，以防止气泡和用于加压气体以分离模具和基底。 在使用中，模具邻近可模制表面设置，并且当模具被压入可模制表面时，气体通过凹槽从图案化区域中排出。 在压印结束或接近结束时，该过程从去除气体切换到施加加压气体。 加压气体通过凹槽并分离或便于模具和可模制表面的分离。