公开(公告)号：US10961554B2

公开(公告)日：2021-03-30

申请号：US16639364

申请日：2019-03-27

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Ji Yeon Lee ,  Jin Sook Chang ,  Hyung Joon Kim ,  Byoung Hoon Yoon ,  Sun Hyoung Choi ,  Yunjung Choi

IPC: C12P13/04 ,  C12N9/10 ,  C12N9/14 ,  C12N15/77 ,  C12N1/21 ,  C12P13/14

Abstract: The present disclosure relates to a novel promoter and a method for producing L-amino acids using the promoter, and more specifically, to a novel polynucleotide having promoter activity, a vector and a microorganism of the genus Corynebacterium comprising the polynucleotide, a method for producing L-amino acids and a fermented composition using the microorganism, and a fermented composition.

公开(公告)号：US10676512B2

公开(公告)日：2020-06-09

申请号：US15508662

申请日：2015-09-04

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Lan Huh ,  Kwang Ho Lee ,  Hyung Joon Kim ,  Jun Ok Moon ,  Song-Gi Ryu

IPC: C12N9/12 ,  C07K14/34 ,  C12P13/08 ,  C12R1/15

Abstract: The present disclosure relates to a novel modified RNA polymerase sigma factor A (SigA) polypeptide; a polynucleotide encoding the same; a microorganism containing the polypeptide; and a method for producing L-lysine using the microorganism.

公开(公告)号：US10662450B2

公开(公告)日：2020-05-26

申请号：US16344189

申请日：2018-06-29

Applicant: CJ Cheiljedang Corporation

Inventor： Hyung Joon Kim ,  Hyo Jin Kim ,  Hyun Won Bae ,  Hyun Ah Kim ,  Chang Il Seo ,  Ji Sun Lee ,  Jin Sook Chang

IPC: C12P13/02 ,  C12N15/77 ,  C12N9/12

Abstract: An aspartokinase variant, a microorganism comprising the variant, and a method for producing an aspartate-derived L-amino acid or a homoserine derivative thereof using the microorganism.

公开(公告)号：US10253339B2

公开(公告)日：2019-04-09

申请号：US15568385

申请日：2016-03-11

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Sang Hee Park ,  Hyung Joon Kim ,  Nam Hyun Kim ,  Jun Ok Moon ,  Jeong Seok Oh ,  Song-Gi Ryu ,  Hyang Choi

IPC: C12P21/00 ,  C12N15/09 ,  C12P13/08 ,  C07K14/195 ,  C07K14/34 ,  C07C229/26 ,  C12N15/77

Abstract: The present invention relates to a novel gluconate repressor variant, a microorganism containing the same, and a method for producing L-lysine using the same.

公开(公告)号：US20180100173A1

公开(公告)日：2018-04-12

申请号：US15568385

申请日：2016-03-11

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Sang Hee Park ,  Hyung Joon Kim ,  Nam Hyun Kim ,  Jun Ok Moon ,  Jeong Seok Oh ,  Song-Gi Ryu ,  Hyang Choi

IPC: C12P13/08 ,  C12N15/77 ,  C07K14/34 ,  C07C229/26

CPC classification number: C12P13/08 ,  C07C229/26 ,  C07K14/195 ,  C07K14/34 ,  C12N15/77

Abstract: The present invention relates to a novel gluconate repressor variant, a microorganism containing the same, and a method for producing L-lysine using the same.

公开(公告)号：US09399784B2

公开(公告)日：2016-07-26

申请号：US14923825

申请日：2015-10-27

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： So Yeon Rah ,  Lan Huh ,  Chang Gyeom Kim ,  Kwang Ho Lee ,  Jun Ok Moon ,  Kyung Han Lee ,  Jin Seok Sung ,  Hyung Joon Kim

IPC: C12P13/08 ,  C12N1/21 ,  C12N9/90 ,  C12N9/12 ,  C12N9/92

CPC classification number: C12P13/08 ,  C12N9/1205 ,  C12N9/92 ,  C12Y207/01017 ,  C12Y503/01005 ,  Y02P20/52

Abstract: The present invention relates to microorganisms of corynebacterium which can utilize xylose and to a method for producing L-lysine using same. More particularly, the present invention relates to microorganisms of corynebacterium which are modified, in which genes encoding xylose isomerase and xylulokinase which are xylose synthases are introduced to express the xylose synthase. The present invention also relates to a method for producing L-lysine, comprising a step of culturing the modified microorganisms of corynebacterium using xylose as a carbon source, and recovering L-lysine from the culture.

公开(公告)号：US09200300B2

公开(公告)日：2015-12-01

申请号：US14371653

申请日：2013-01-10

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： So Yeon Rah ,  Lan Huh ,  Chang Gyeom Kim ,  Kwang Ho Lee ,  Jun Ok Moon ,  Kyung Han Lee ,  Jin Seok Sung ,  Hyung Joon Kim

IPC: C12P13/08 ,  C12N1/21 ,  C12N9/90 ,  C12N9/12 ,  C12N9/92

CPC classification number: C12P13/08 ,  C12N9/1205 ,  C12N9/92 ,  C12Y207/01017 ,  C12Y503/01005 ,  Y02P20/52

Abstract: The present invention relates to microorganisms of corynebacterium which can utilize xylose and to a method for producing L-lysine using same. More particularly, the present invention relates to microorganisms of corynebacterium which are modified, in which genes encoding xylose isomerase and xylulokinase which are xylose synthases are introduced to express the xylose synthase. The present invention also relates to a method for producing L-lysine, comprising a step of culturing the modified microorganisms of corynebacterium using xylose as a carbon source, and recovering L-lysine from the culture.

Abstract translation: 本发明涉及能够利用木糖的棒状杆菌的微生物和使用其的L-赖氨酸的制造方法。 更具体地，本发明涉及被修饰的棒状杆菌的微生物，其中引入木糖异构酶和木酮糖激酶的基因是木糖合成酶来表达木糖合酶。 本发明还涉及L-赖氨酸的制造方法，其特征在于，包括使用木糖作为碳源培养棒状杆菌的修饰微生物并从培养物中回收L-赖氨酸的步骤。

公开(公告)号：US11352608B2

公开(公告)日：2022-06-07

申请号：US16466940

申请日：2019-03-08

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Sun Hyoung Choi ,  Jin Sook Chang ,  Hyung Joon Kim ,  Byoung Hoon Yoon ,  Ji Yeon Lee ,  Yunjung Choi

IPC: C12N9/04 ,  C12N7/00 ,  C12N15/00 ,  C12N1/20 ,  C12N15/77 ,  C12P7/00 ,  C12P13/14

Abstract: The present disclosure relates to a novel promoter and a method for producing L-amino acids using the promoter, and more specifically, to a novel polynucleotide having promoter activity, a vector and a microorganism of the genus Corynebacterium comprising the polynucleotide, a method for producing L-amino acids using the microorganism, and a fermented composition.

公开(公告)号：US10787690B2

公开(公告)日：2020-09-29

申请号：US16461327

申请日：2017-09-19

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hyo Jeong Byun ,  Hyung Joon Kim ,  Hyun Won Bae ,  Song-Gi Ryu ,  Hyang Choi ,  Jun Ok Moon ,  Kyung-Chang Lee ,  Yunjung Choi

IPC: C12P13/08 ,  C12R1/16

Abstract: The present disclosure relates to a microorganism producing L-lysine, and a method for producing L-lysine using the same.

公开(公告)号：US10526586B2

公开(公告)日：2020-01-07

申请号：US15557013

申请日：2016-03-15

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Lan Huh ,  Jun Ok Moon ,  Hyun Won Bae ,  Hyung Joon Kim ,  Sung Ki Song

IPC: C12N9/02 ,  C12N1/20 ,  C12N15/53 ,  C12P13/04 ,  C12N15/77 ,  C12P13/08

Abstract: The present disclosure relates to a novel pyruvate dehydrogenase variant, a polynucleotide encoding the pyruvate dehydrogenase variant, a microorganism of the genus Corynebacterium producing L-amino acid, which includes the pyruvate dehydrogenase variant, and a method for producing an L-amino acid using the microorganism.