公开(公告)号：US11524981B2

公开(公告)日：2022-12-13

申请号：US17268691

申请日：2020-03-20

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Moo Young Jung ,  Hyun Ah Kim ,  Chang Il Seo ,  Imsang Lee ,  Ji-won Kim ,  Tae Yeon Kim ,  Sung Kwang Son ,  Ki Yong Cheong

IPC: C12P13/22 ,  C12N1/21 ,  C12N15/74 ,  C12N15/77 ,  C07K14/195 ,  C12R1/15 ,  C12R1/19

Abstract: The present disclosure relates to a protein variant having a tryptophan-exporting activity, an L-tryptophan-producing microorganism expressing the protein variant, and a method for producing L-tryptophan using the microorganism.

公开(公告)号：US11236374B2

公开(公告)日：2022-02-01

申请号：US16483309

申请日：2019-05-21

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hyo Jin Kim ,  Lan Huh ,  Sang Jo Lim ,  Hyun Ah Kim ,  Hyoung Joon Kim ,  Chang il Seo ,  Seung Bin Lee ,  Ji Sun Lee

IPC: C12P13/06 ,  C12N1/20 ,  C12P13/08 ,  C12P13/12 ,  C12N9/04

Abstract: The present disclosure relates to modified homoserine dehydrogenase and a method for producing a homoserine-derived L-amino acid using the same.

公开(公告)号：US20200224228A1

公开(公告)日：2020-07-16

申请号：US16627572

申请日：2018-06-29

Applicant: CJ CheilJedang Corporation

Inventor： Kyungrim Kim ,  Jihyun Shim ,  Hyun Ah Kim ,  Yong Uk Shin ,  Peter Lee

IPC: C12P13/06 ,  C12P13/12

Abstract: The present disclosure relates to an O-succinyl homoserine transferase mutant, a polynucleotide encoding the same, a microorganism including the mutant, and a method of producing O-succinyl homoserine using the microorganism.

公开(公告)号：US10662450B2

公开(公告)日：2020-05-26

申请号：US16344189

申请日：2018-06-29

Applicant: CJ Cheiljedang Corporation

Inventor： Hyung Joon Kim ,  Hyo Jin Kim ,  Hyun Won Bae ,  Hyun Ah Kim ,  Chang Il Seo ,  Ji Sun Lee ,  Jin Sook Chang

IPC: C12P13/02 ,  C12N15/77 ,  C12N9/12

Abstract: An aspartokinase variant, a microorganism comprising the variant, and a method for producing an aspartate-derived L-amino acid or a homoserine derivative thereof using the microorganism.

公开(公告)号：US11142779B2

公开(公告)日：2021-10-12

申请号：US16627655

申请日：2018-06-29

Applicant: CJ CheilJedang Corporation

Inventor： Kyungrim Kim ,  Jihyun Shim ,  Hyun Ah Kim ,  Yong Uk Shin ,  Peter Lee

IPC: C12N9/10 ,  C12N1/21 ,  C12P13/06 ,  C12P13/12 ,  C12N9/12

Abstract: Provided are an O-succinyl homoserine transferase variant, a polynucleotide encoding the variant, a microorganism comprising the variant, and a method of producing O-succinyl homoserine using the microorganism.

公开(公告)号：US10815509B2

公开(公告)日：2020-10-27

申请号：US16577837

申请日：2019-09-20

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hyun Ah Kim ,  Ju Hee Seo ,  Yong Uk Shin ,  So Young Kim ,  Sang Kyoum Kim ,  Kwang Ho Na ,  Jee Yeon Bae ,  Sung Kwang Son ,  Hye Ryun Yoo ,  Jin Geun Choi

IPC: C12N1/21 ,  C12N15/54 ,  C12N15/53 ,  C12N15/60 ,  C12N9/10 ,  C12P13/04 ,  C12P13/12 ,  C12P13/06 ,  C12N9/12 ,  C12N9/88 ,  C12N15/52

Abstract: Disclosed is a microorganism of Escherichia sp. producing O-acetyl homoserine, and a method of producing O-acetyl homoserine in high yield using the microorganism.

公开(公告)号：US11555213B2

公开(公告)日：2023-01-17

申请号：US17472028

申请日：2021-09-10

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Hyo Jin Kim ,  Lan Huh ,  Sang Jo Lim ,  Hyun Ah Kim ,  Hyoung Joon Kim ,  Chang il Seo ,  Seung Bin Lee ,  Ji Sun Lee

IPC: C12N9/04 ,  C12P13/06 ,  C12N1/20 ,  C12P13/08 ,  C12P13/12

Abstract: The present disclosure relates to modified homoserine dehydrogenase and a method for producing a homoserine-derived L-amino acid using the same.

公开(公告)号：US20220009973A1

公开(公告)日：2022-01-13

申请号：US17268691

申请日：2020-03-20

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Moo Young Jung ,  Hyun Ah Kim ,  Chang Il Seo ,  Imsang Lee ,  Ji-won Kim ,  Tae Yeon Kim ,  Sung Kwang Son ,  Ki Yong Cheong

IPC: C07K14/195 ,  C12P13/22

Abstract: The present disclosure relates to a protein variant having a tryptophan-exporting activity, an L-tryptophan-producing microorganism expressing the protein variant, and a method for producing L-tryptophan using the microorganism.

公开(公告)号：US10995378B2

公开(公告)日：2021-05-04

申请号：US16479749

申请日：2019-02-22

Applicant: CJ Cheiljedang Corporation

Inventor： Moo Young Jung ,  Chang Il Seo ,  Hyo Jin Kim ,  Tae Yeon Kim ,  Hyun Ah Kim ,  Sung Kwang Son ,  Hye Ryun Yoo ,  Jae Min Lee ,  Ki Yong Cheong

IPC: C12P13/22 ,  C12N1/21 ,  C07K14/195 ,  C12R1/19 ,  C12N15/70 ,  C12N15/77 ,  C12R1/15

Abstract: The present disclosure relates to a microorganism producing L-tryptophan in which the microorganism is modified such that a protein having an L-tryptophan-exporting activity comprising the amino acid sequence of SEQ ID NO: 1 is expressed, and a method for producing L-tryptophan using the microorganism.

公开(公告)号：US10597686B2

公开(公告)日：2020-03-24

申请号：US16514777

申请日：2019-07-17

Applicant: CJ Cheiljedang Corporation

Inventor： Jee Yeon Bae ,  Ji Hyun Shim ,  Hyun Ah Kim ,  Juhee Seo ,  Yong Uk Shin ,  Jae Hee Lee ,  Sang Kyoum Kim ,  So Young Kim

IPC: C12P13/06 ,  C12P13/12 ,  C12N15/70 ,  C07K14/245

Abstract: The present disclosure relates to a protein having the activity of exporting O-acetylhomoserine and a novel modified protein thereof, a microorganism capable of producing O-acetylhomoserine with enhanced expression of the protein, and a method for producing O-acetylhomoserine using the microorganism.