摘要:
Devices and methods for performing extracellular recording of cells, such as excitable cells, cardiomyocytes, and cardiomyocyte precursor cells is provided. An exemplary device includes a nonconductive substrate forming or provided as a base of one or more wells; a recording electrode positioned on the substrate within the well, wherein the recording electrode is accessible to cells when a cell sample is added to the device; and a reference electrode positioned within the well in a cell-free zone, the cell-free zone characterized as free from contact with cells when the cell sample is added to the device, thereby preventing contact between cells and the reference electrode.
摘要:
Devices and methods for performing extracellular recording of cells, such as excitable cells, cardiomyocytes, and cardiomyocyte precursor cells is provided. An exemplary device includes a nonconductive substrate forming or provided as a base of one or more wells; a recording electrode positioned on the substrate within the well, wherein the recording electrode is accessible to cells when a cell sample is added to the device; and a reference electrode positioned within the well in a cell-free zone, the cell-free zone characterized as free from contact with cells when the cell sample is added to the device, thereby preventing contact between cells and the reference electrode.
摘要:
A method of determining one or more beating parameters for use in cardiomyocyte beating analysis including: providing a cell analysis device including wells, each well including a sensor capable of monitoring beating of cardiomyoctes in millisecond time resolution; adding cardiomyocytes to the wells; monitoring the beating of the cardiomyocytes in millisecond time resolution to obtain a plurality of beating measurements; and calculating one or more beating parameters from the plurality of beating measurements.
摘要:
A method for message interworking, a Session Initiation System messaging server, an interworking gateway and a system for message interworking are disclosed. The method for message interworking includes: receiving, by an SIP messaging server, an SIP message, and routing the SIP message to a recipient; receiving an SIP response to the SIP message; sending the SIP message to an interworking gateway when it is determined that message interworking is required, so that the interworking gateway may perform a protocol conversion on the SIP message and send the converted non-SIP message to a corresponding non-SIP messaging system, or, so that the interworking gateway may establish a session between the interworking gateway itself and a sender terminal, receive an SIP session message via the established session, perform a protocol conversion on the SIP session message and then send the converted non-SIP message to a corresponding non-SIP messaging system.
摘要:
A method for purification and conditioning of crude syngas based on properties of molten salts, includes removing particles at a high-temperature by enabling the high-temperature crude syngas produced by a gasification device to firstly pass through a high-temperature particle removal device to remove solid particles in the gas; removing hydrocarbons in the presence of oxygen by introducing an oxidant into the crude syngas after treatment, selectively removing the hydrocarbons in the crude syngas and simultaneously utilizing high temperature produced by oxidation of the hydrocarbons to crack tar; and removing gas pollutants and conditioning by introducing the obtained crude syngas into molten salts medium, removing pollutants containing sulfur and chlorine in the crude syngas, and simultaneously adjusting the H2/CO ratio of the syngas to obtain purified syngas.
摘要:
An anodized layer on a metallic substrate is treated in a manner to directly electrodeposit a metal sulfide solid lubricant material represented by MS2, where M is Mo, W or other suitable metal, in pores of the anodized layer without any subsequent thermal and/or chemical treatment being needed.
摘要:
A method and apparatus for microfluidic processing by programmably manipulating a packet. A material is introduced onto a reaction surface and compartmentalized to form a packet. A position of the packet is sensed with a position sensor. A programmable manipulation force is applied to the packet at the position. The programmable manipulation force is adjustable according to packet position by a controller. The packet is programmably moved according to the programmable manipulation force along arbitrarily chosen paths.
摘要:
A precise-clock synchronization method and system and a precise-clock frequency/time synchronization device are provided. In the embodiments of the present invention, two time stamp engines are provided at a slave clock side. A relative time stamp engine provides a relative arrival time stamp. An absolute time stamp engine provides an absolute arrival time stamp. The frequency/time synchronization is calculated by using different time stamps obtained from different time stamp engines, so the frequency synchronization and time synchronization of the master clock and the slave clock may be separately accomplished, and one synchronization function may be enabled or disabled. Therefore, the frequency synchronization and time synchronization of the master clock and the slave clock do not interfere with each other, thus greatly reducing the occupied link bandwidth resources.
摘要:
A method and device for improving clock stability are provided. The method includes: determining whether a difference between a current sender timestamp (ST) and a current receiver timestamp (RT) is a mutated value; pre-processing the ST and RT, if the difference between the ST and RT is a mutated value; acquiring a service clock according to the pre-processed ST and RT; and sending time division multiplex (TDM) data according to the service clock.. Through the embodiments of the present disclosure, a packet delay variance (PDV) may be smoothed, the impairment of the PDV on clock recovery may be reduced, the quality of the clock recovery may be improved, and the problem of clock synchronization may be solved through the mutation processing on the timestamps.
摘要:
The present invention provides substituted di-, tri-, tetra- and penta-sulfide compounds and compositions, and methods of using the same for the treatment and/or prevention of a cell proliferative disorder. The present invention also provides methods for preparing trisulfide compounds and compositions.