-
公开(公告)号:US11925550B2
公开(公告)日:2024-03-12
申请号:US17694578
申请日:2022-03-14
Applicant: Edwards Lifesciences Corporation
Inventor: Tomer Saar , Michael Bukin , Elena Sherman , Alexander Barash , Yana Mayatskaya
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2210/0014 , A61F2220/0075
Abstract: An implantable prosthetic valve that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration includes an annular frame including a plurality of angled strut members, a plurality of leaflets disposed within the frame and secured to the frame, and a skirt member secured to the frame. The skirt member is disposed about an edge portion of a leaflet of the plurality of leaflets, and the skirt member includes a plurality of extension portions wrapped around at least one strut member. A cord member is threaded through at least a portion of the plurality of extension portions in a direction along an axis of the at least one strut member to secure the skirt member to the at least one strut member.
-
公开(公告)号:US20240024101A1
公开(公告)日:2024-01-25
申请号:US18373892
申请日:2023-09-27
Applicant: EDWARDS LIFESCIENCES CORPORATION
Inventor: Tamir S. Levi , Nikolai Gurovich , Karin Lavon , Elena Sherman
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2220/0025
Abstract: A prosthetic heart valve including a radially expandable and compressible annular frame is disclosed. The frame includes a plurality of interconnected struts defining a plurality of rows of cells arranged between an inflow end and an outflow end of the frame, the interconnected struts comprising a plurality of outflow struts defining the outflow end and a plurality of inflow struts defining the inflow end. The frame further includes a plurality of apex regions formed at the inflow end and the outflow end, each apex region curving between two angled strut portions and forming one of the outflow struts or one of the inflow struts with the two angled strut portions. Each apex region has a narrowed width and a length that extends along at least 25% of a total length of the outflow strut or inflow strut, the narrowed width smaller than a width of the two angled strut portions.
-
公开(公告)号:US11793632B2
公开(公告)日:2023-10-24
申请号:US16516089
申请日:2019-07-18
Applicant: Edwards Lifesciences Corporation
Inventor: Tamir S. Levi , Son V. Nguyen , Netanel Benichou , David Maimon , Ziv Yohanan , Nikolay Gurovich , Bella Felsen , Larisa Dadonkina , Ron Sharoni , Elena Sherman
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2433 , A61F2220/0075 , A61F2230/0054 , A61F2250/0036 , A61F2250/0097
Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. A valve frame can have a tapered profile when mounted on a delivery shaft, with an inflow end portion having a smaller diameter than an outflow end portion. The valve can comprise generally V-shaped leaflets, reducing material within the inflow end of the frame. An outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack when the valve is expanded and lying flat against the frame when the valve is collapsed. A diagonally woven inner skirt can elongate axially with the frame. Side tabs of adjacent leaflets can extend through and be secured to window frame portions of the frame to form commissures. The window frame portions can be depressed radially inward relative to surrounding frame portions when the valve is crimped onto a delivery shaft.
-
公开(公告)号:US11759320B2
公开(公告)日:2023-09-19
申请号:US17710836
申请日:2022-03-31
Applicant: Edwards Lifesciences Corporation
Inventor: Tamir S. Levi , Son V. Nguyen , Netanel Benichou , David Maimon , Ziv Yohanan , Nikolay Gurovich , Bella Felsen , Larisa Dadonkina , Ron Sharoni , Elena Sherman
IPC: A61F2/24
CPC classification number: A61F2/2418 , A61F2/2412 , A61F2/2433 , A61F2220/0075 , A61F2230/0054 , A61F2250/0036 , A61F2250/0097
Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. A valve frame can have a tapered profile when mounted on a delivery shaft, with an inflow end portion having a smaller diameter than an outflow end portion. The valve can comprise generally V-shaped leaflets, reducing material within the inflow end of the frame. An outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack when the valve is expanded and lying flat against the frame when the valve is collapsed. A diagonally woven inner skirt can elongate axially with the frame. Side tabs of adjacent leaflets can extend through and be secured to window frame portions of the frame to form commissures. The window frame portions can be depressed radially inward relative to surrounding frame portions when the valve is crimped onto a delivery shaft.
-
公开(公告)号:US11690710B2
公开(公告)日:2023-07-04
申请号:US17660394
申请日:2022-04-22
Applicant: Edwards Lifesciences Corporation
Inventor: Ziv Yohanan , Tamir S. Levi , Netanel Benichou , Michael Bukin , Nikolai Gurovich , Elena Sherman
IPC: A61F2/24
CPC classification number: A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2/2433 , A61F2220/0075 , A61F2230/0013 , A61F2230/0054 , A61F2250/0036 , A61F2250/0039
Abstract: A method of implanting a prosthetic heart valve within a patient can comprise inserting a distal end portion of a delivery apparatus and a prosthetic heart valve into the patient and advancing the prosthetic heart valve to a deployment location within the heart of the patient and inflating one or more of a plurality of differently-sized balloons in a balloon-assembly on the distal end portion of the delivery apparatus. The prosthetic heart valve can be mounted on the balloon assembly in a crimped state and the inflating of the one or more of the plurality of differently-sized balloons can expand the prosthetic heart valve from the crimped state to a radially expanded state having a non-cylindrical shape.
-
公开(公告)号:US20220234306A1
公开(公告)日:2022-07-28
申请号:US17719262
申请日:2022-04-12
Applicant: Edwards Lifesciences Corporation
Inventor: Itai Pelled , Elena Sherman , Eran Goldberg , Kevin D. Rupp , Noam Nir
Abstract: A prosthetic heart valve has a radially expandable and collapsible annular frame, the frame having an inflow end and an outflow end and defining a longitudinal axis along a lumen of the prosthetic heart valve when it is in the expanded configuration. A leaflet structure is positioned within the frame and secured thereto. The prosthetic heart valve also has a laminate sealing member including a plurality of layers heat-bonded together to encapsulate at least a portion of the frame. The laminate sealing member extends along the longitudinal axis in an upstream direction and doubles back toward the outflow end of the frame at a fold line to form a cuff, and an edge portion of the laminate sealing member is secured to a main portion of the laminate sealing member downstream of the fold line such that the cuff forms an inflow end of the laminate sealing member.
-
公开(公告)号:US20220226111A1
公开(公告)日:2022-07-21
申请号:US17710836
申请日:2022-03-31
Applicant: Edwards Lifesciences Corporation
Inventor: Tamir S. Levi , Son V. Nguyen , Netanel Benichou , David Maimon , Ziv Yohanan , Nikolay Gurovich , Bella Felsen , Larisa Dadonkina , Ron Sharoni , Elena Sherman
IPC: A61F2/24
Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. A valve frame can have a tapered profile when mounted on a delivery shaft, with an inflow end portion having a smaller diameter than an outflow end portion. The valve can comprise generally V-shaped leaflets, reducing material within the inflow end of the frame. An outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack when the valve is expanded and lying flat against the frame when the valve is collapsed. A diagonally woven inner skirt can elongate axially with the frame. Side tabs of adjacent leaflets can extend through and be secured to window frame portions of the frame to form commissures. The window frame portions can be depressed radially inward relative to surrounding frame portions when the valve is crimped onto a delivery shaft.
-
公开(公告)号:US20220023038A1
公开(公告)日:2022-01-27
申请号:US17492408
申请日:2021-10-01
Applicant: Edwards Lifesciences Corporation
Inventor: Nikolay Gurovich , Michael Bukin , Alexey Tsypenyuk , Elena Sherman , Dikla Kersh , Boaz Manash , Liron Tayeb , Ziv Yohanan , Alexander Barash , Yair A. Neumann , Tomer Saar
IPC: A61F2/24
Abstract: A prosthetic valve has an annular frame including a plurality of strut members that is radially collapsible to a collapsed configuration and radially expandable to an expanded configuration. A leaflet structure is situated at least partially within the frame. The leaflet structure includes a plurality of leaflets, each leaflet having opposing commissure tab portions on opposite sides of the leaflet. Each commissure tab portion is paired with an adjacent commissure tab portion of an adjacent leaflet to form a commissure. The commissure tab portions of each leaflet are folded to form a plurality of layers positioned on the inside of the frame. A reinforcement member is positioned between the layers of each commissure tab portion.
-
公开(公告)号:US20220023036A1
公开(公告)日:2022-01-27
申请号:US17496670
申请日:2021-10-07
Applicant: Edwards Lifesciences Corporation
Inventor: Tamir S. Levi , Elena Sherman , Noam Nir
IPC: A61F2/24
Abstract: A method of assembling a prosthetic heart valve comprises securing a suture loop having at least first and second windings to an outflow edge portion of an inner skirt. The first and second windings are arranged in a repeating pattern of figure-eight shape curves and each winding has a plurality of first sections attached to the outflow edge portion of the inner skirt and a plurality of second sections unattached to the inner skirt. The inner skirt is placed inside of an annular frame and the second sections of the first and second windings are placed over apices of an outflow end of the frame such that the second sections of the first and second windings reside outside of the frame. The second sections of the windings are inserted inwardly through openings in the frame and attached to selected locations on the inner skirt.
-
公开(公告)号:US20210386543A1
公开(公告)日:2021-12-16
申请号:US17460079
申请日:2021-08-27
Applicant: Edwards Lifesciences Corporation
Inventor: Tamir S. Levi , Ron Sharoni , Elena Sherman , Oren H. Wintner , Kevin D. Rupp , Son V. Nguyen , Ajay Chadha , Jeff Lindstrom
IPC: A61F2/24
Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve and method for crimping the prosthetic heart valve are disclosed. A method of radially compressing a prosthetic valve can include partially inserting the valve while in a radially expanded configuration into a crimping device comprising crimper jaws, wherein a portion of the valve comprising an outer skirt extends outside of the crimper jaws. The method can further include crimping the valve to a first partially collapsed configuration, further inserting the valve into the crimping device, such that the outer skirt is between the crimper jaws, and crimping the valve to a second partially collapsed configuration, wherein a diameter of the valve is smaller in the second partially collapsed configuration than in the first partially collapsed configuration.
-
-
-
-
-
-
-
-
-