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    Teleoperation Of Machines Having At Least One Actuated Mechanism And A Fault Detection And Recovery System
    21.
    发明申请
    Teleoperation Of Machines Having At Least One Actuated Mechanism And A Fault Detection And Recovery System 有权
    具有至少一个致动机构和故障检测和恢复系统的机器的远程操作

    公开(公告)号：US20150314447A1

    公开(公告)日：2015-11-05

    申请号：US14649160

    申请日：2013-12-03

    申请人： Biao ZHANG ,  Jianjun WANG ,  George Q. ZHANG ,  Sangeun CHOI ,  Remus BOCA ,  Thomas A. FUHLBRIGGE ,  Thomas GROTH

    发明人： Biao Zhang ,  Jianjun Wang ,  George Q. Zhang ,  Sangeun Choi ,  Remus Boca ,  Thomas A. Fuhlbrigge ,  Tomas Groth

    IPC分类号： B25J9/16

    CPC分类号： B25J9/1689 ,  G05B2219/40195 ,  G05B2219/40204 ,  Y10S901/09 ,  Y10S901/46

    摘要： A machine has at least one actuated mechanism is remotely located from a control station. A two way real-time communication link connects the machine location with the control station. A controller at the machine location has program code that is configured to determine from data from one or more sensors at the machine location if an actual fault has occurred in the machine when the machine is performing its predetermined function and to determine for an actual fault one or more types for the fault and transmit the one or more fault types to the control station for analysis. The code in the controller is configured to be a preprogrammed trap routine specific to the machine function that is automatically executed when an error in machine operation is detected at the machine location. The controller also has a default trap routine that is executed when specific routine does not exist.

    摘要翻译： 机器具有远离控制站的至少一个致动机构。 双向实时通信链路将机器位置与控制站相连。 在机器位置处的控制器具有程序代码，其被配置为从机器位置的一个或多个传感器的数据确定机器是否在机器执行其预定功能时发生实际故障并确定实际故障 或更多类型的故障，并将一个或多个故障类型传输到控制站进行分析。 控制器中的代码被配置为特定于机器功能的预编程陷阱程序，在机器位置检测到机器操作错误时自动执行。 控制器还具有默认的陷阱程序，当特定例程不存在时，它将被执行。

    Intracellular microbubble for imaging an anatomical site
    22.
    发明授权
    Intracellular microbubble for imaging an anatomical site 有权
    用于成像解剖部位的细胞内微泡

    公开(公告)号：US08940277B2

    公开(公告)日：2015-01-27

    申请号：US12613400

    申请日：2009-11-05

    申请人： Jianjun Wang ,  Flordeliza Villanueva ,  Xucai Chen ,  Andrew Fisher ,  William Richard Wagner

    发明人： Jianjun Wang ,  Flordeliza Villanueva ,  Xucai Chen ,  Andrew Fisher ,  William Richard Wagner

    IPC分类号： A61B8/00 ,  A61B8/08 ,  A61K49/22

    CPC分类号： A61K49/222 ,  A61B8/481

    摘要： This invention addresses the clinical problem of how to optimize biological cell based therapies, such as stem cell therapy. Currently, cell therapies administered by intravenous, intra-arterial, and/or direct tissue injection are limited by the lack of clinically available imaging methods to detect the in vivo fate of the administered cells. There are many efforts underway to develop imaging strategies for stem cells in vivo, including radionuclide and MRI-based approaches. However, these approaches are limited by potential safety issues (e.g. radioactive exposure of stem cells, toxicity of iron particles used for MRI) and difficulty in serial tracking due to complex instrumentation and/or the requirement for repetitive radiation exposure.

    摘要翻译： 本发明解决了如何优化基于生物细胞的疗法（如干细胞治疗）的临床问题。 目前，通过静脉内，动脉内和/或直接组织注射施用的细胞疗法受到缺乏临床可用的成像方法的限制，以检测所施用细胞的体内命运。 目前正在开展许多努力来开发体内干细胞成像策略，包括放射性核素和基于MRI的方法。 然而，这些方法受到潜在安全问题的限制（例如干细胞的放射性暴露，用于MRI的铁颗粒的毒性）以及由于复杂的仪器和/或对重复辐射暴露的要求而导致的串行跟踪困难。

    Method and composition for a protein transduction technology and its applications
    23.
    发明授权
    Method and composition for a protein transduction technology and its applications 有权
    蛋白转导技术的方法和组成及其应用

    公开(公告)号：US08722348B2

    公开(公告)日：2014-05-13

    申请号：US12128320

    申请日：2008-05-28

    申请人： Jianjun Wang ,  Qianqian Li

    发明人： Jianjun Wang ,  Qianqian Li

    IPC分类号： G01N33/567

    CPC分类号： A61K38/00 ,  A61K47/48046 ,  A61K47/48176 ,  C12N15/88 ,  C12P21/00 ,  G01N33/5023 ,  G01N33/58 ,  G01N33/68 ,  G01N2458/15

    摘要： A protein transduction method for efficiently delivery of exogenous proteins into mammalian cells is invented, which has the capability of targeting different cellular compartments and protection from degradation of the delivered proteins from cellular proteases. A composition for treat proteins has cation reagents, lipids and enhancers in a carrier. The method can be used in a number of ways including: production of large quantities of properly folded, post-translationally modified proteins using mammalian cell machinery, a in-cell fluorescence spectroscopy and imaging using small molecule fluorophores and a in-cell NMR spectroscopy using living mammalian cells. The method permits cell biology at atomic resolution that is physiologically and pathological relevant and permits protein therapy to treat human diseases. The method can also be used to deliver exogenous protein inside mammalian cells, wherein the exogenous proteins follow a similar secretion pathway as that of the endogenous protein.

    摘要翻译： 发明了用于将外源蛋白有效递送到哺乳动物细胞中的蛋白质转导方法，其具有靶向不同细胞区室的能力并且防止递送的蛋白质从细胞蛋白酶降解。 用于处理蛋白质的组合物在载体中具有阳离子试剂，脂质和增强剂。 该方法可以以多种方式使用，包括：使用哺乳动物细胞机制产生大量正确折叠的翻译后修饰蛋白，使用小分子荧光团进行细胞内荧光光谱和成像，并使用细胞内核磁共振光谱 活哺乳动物细胞。 该方法允许细胞生物学在原子分辨率下与生理和病理相关，并允许蛋白质治疗来治疗人类疾病。 该方法还可用于在哺乳动物细胞内递送外源蛋白质，其中外源蛋白质遵循与内源性蛋白质相似的分泌途径。

    Apparatus having sterilant monitoring system
    27.
    发明授权
    Apparatus having sterilant monitoring system 失效
    具有灭菌剂监测系统的装置

    公开(公告)号：US06537491B1

    公开(公告)日：2003-03-25

    申请号：US09360781

    申请日：1999-07-26

    申请人： Jianjun Wang ,  David A. Mondiek ,  Patrick D. Simon

    发明人： Jianjun Wang ,  David A. Mondiek ,  Patrick D. Simon

    IPC分类号： G05B100

    CPC分类号： A61L2/24 ,  A23L3/003 ,  A61L2/28

    摘要： Sterilization apparatus includes a monitoring system capable of continuously monitoring levels of a sterilant, such as hydrogen peroxide vapor. The monitoring system includes a sensor chamber joined in fluid communication with a sterilant supply conduit of the sterilization apparatus. A gas-detecting semiconductor sensing element, and associated temperature sensor, are provided within the sensor chamber to provide output signals corresponding to detected levels of sterilant. The sensor chamber isolates parametric influence, such as relative humidity, temperature and flow rate, to provide more accurate concentration level readings. A data collection circuit is operatively coupled to the sensors to provide an output corresponding to detected levels of sterilant within the apparatus. The data collection circuit may include an electronic memory to store the collected data, and signal connectors, such as data ports for a physical connection or transmitters for a remote transmission, to transfer the signals representative of the collected data to a remote communication unit. A processor chip or circuit may be provided proximate the sensor chamber, and a processor may be provided in communication with the remote communication unit. The monitoring system can be controlled using a circuit to select conditions for operation, or by remote control using near infrared or radio wave signals.

    摘要翻译： 杀菌装置包括能够连续监测灭菌剂如过氧化氢蒸汽的水平的监测系统。 监测系统包括与灭菌装置的灭菌剂供应管道流体连通的传感器室。 在传感器室内提供气体检测半导体感测元件和相关联的温度传感器，以提供对应于检测到的灭菌剂水平的输出信号。 传感器室隔离参数影响，如相对湿度，温度和流量，以提供更准确的浓度水平读数。 数据采集​​电路可操作地耦合到传感器以提供对应于设备内检测到的消毒剂水平的输出。 数据采集​​电路可以包括用于存储所收集的数据的电子存储器和用于物理连接的数据端口或用于远程传输的发射机的信号连接器，以将表示所收集的数据的信号传送到远程通信单元。 可以在传感器室附近提供处理器芯片或电路，并且可以提供与远程通信单元通信的处理器。 可以使用电路来控制监控系统，以选择操作条件，或通过使用近红外或无线电波信号进行远程控制。

    Method and apparatus for analyzing flowable products
    28.
    发明授权
    Method and apparatus for analyzing flowable products 失效
    用于分析流动产品的方法和装置

    公开(公告)号：US6006590A

    公开(公告)日：1999-12-28

    申请号：US904120

    申请日：1997-07-31

    申请人： Jianjun Wang

    发明人： Jianjun Wang

    IPC分类号： G01N29/02 ,  G01N29/036 ,  G01N29/07 ,  G01N29/11 ,  G01N29/22 ,  G01N29/30 ,  G01N29/00

    CPC分类号： G01N29/075 ,  G01N29/036 ,  G01N29/11 ,  G01N29/225 ,  G01N29/30 ,  G01N2291/015 ,  G01N2291/2695

    摘要： A method and system for ultrasonically analyzing flowable products. The method includes the steps of providing a flowable product to be ultrasonically analyzed. In addition the method includes the steps of providing a means for generating and receiving ultrasonic waves, a processing unit, and a means for agitating the flowable product. A flowable product is agitated using the means for agitating. The means for generating and receiving ultrasonic waves is then placed in ultrasonic contact with the flowable product and ultrasonic waves are directed into the flowable product. Ultrasonic waves are received using the means for generating and receiving ultrasonic waves and the received waves are transmitted to the processing unit where they are processed by establishing respective vectors for a plurality of reflective contents of the flowable product and by comparing the respective vectors to a predetermined, acceptable statistical range of vectors. The system includes a means for conveying a flowable product where the means for conveying includes an agitating means for agitating the flowable product. The system further includes a means for generating and receiving a plurality of ultrasonic waves, a means for selectively placing the means for generating and receiving in ultrasonic contact with the flowable product on said means for conveying, and a processing means for analyzing ultrasonic waves received by the means for generating and receiving. The processing means includes a means for establishing respective vectors for a plurality of reflective contents of the flowable product and a means for comparing the respective vectors to a predetermined, acceptable statistical range of vectors.

    摘要翻译： 一种用于超声波分析流动产品的方法和系统。 该方法包括提供可超声波分析的可流动产品的步骤。 此外，该方法包括提供用于产生和接收超声波的装置，处理单元和用于搅拌可流动产品的装置的步骤。 使用搅拌装置搅拌可流动的产品。 然后，用于产生和接收超声波的装置与可流动产品超声波接触，超声波被引导到可流动产品中。 使用用于生成和接收超声波的装置接收超声波，并且通过为可流动产品的多个反射内容建立相应的矢量将接收的波发送到处理单元，在处理单元处进行处理，并且通过将各个向量与预定的 ，可接受的载体统计范围。 该系统包括用于输送可流动产品的装置，其中用于输送的装置包括用于搅拌可流动产品的搅拌装置。 该系统还包括用于产生和接收多个超声波的装置，用于选择性地将用于产生和接收的装置与可流动产品超声波接触的装置在所述输送装置上的装置，以及用于分析由 生成和接收的手段。 处理装置包括用于建立可流动产品的多个反射内容物的相应矢量的装置和用于将各个矢量与预定的，可接受的矢量的统计范围进行比较的装置。

    Connection assembly protection
    29.
    发明授权
    Connection assembly protection 有权

    公开(公告)号：US10128393B2

    公开(公告)日：2018-11-13

    申请号：US13187107

    申请日：2011-07-20

    申请人： Brian E. Cohen ,  Jianjun Wang ,  Rui Xiao

    发明人： Brian E. Cohen ,  Jianjun Wang ,  Rui Xiao

    IPC分类号： H01L31/05 ,  H01L31/02 ,  H02S40/34

    摘要： A photovoltaic module may include an electrical connection assembly with increased corrosion protection. The module may be protected from corrosion by using a high number of photovoltaic cells, by providing protective materials over module components subject to corrosion, and/or by adjusting the size ratio of the positive components to the negative components within the module.