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公开(公告)号:US11554371B2
公开(公告)日:2023-01-17
申请号:US17138024
申请日:2020-12-30
Applicant: International Business Machines Corporation
Inventor: Ricardo Luis Ohta , Jaione Tirapu Azpiroz , Matheus Esteves Ferreira , Daniel Vitor Lopes Marcondes Marçal , Ademir Ferreira Da Silva , Mathias B Steiner
Abstract: Devices and methods for controlling collection of liquid sample are described. In an example, a microfluidic device can include an analytical device and an actuator. The actuator can be connected to the analytical device. The actuator can be operable to absorb fluid. The actuator can guide the absorbed fluid to an input layer of the analytical device. The actuator can deform in response to an occurrence of an absorption condition. A degree of deformation of the actuator indicates a volume of fluid collected by the analytical device.
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公开(公告)号:US11376582B2
公开(公告)日:2022-07-05
申请号:US16293262
申请日:2019-03-05
Applicant: International Business Machines Corporation
Inventor: Jaione Tirapu Azpiroz , Matheus Esteves Ferreira , Ademir Ferreira da Silva , Ricardo Luis Ohta , Mathias Steiner
IPC: B01L3/00
Abstract: Fabricating a fluid testing device includes receiving a substrate, and applying a pattern of hydrophobic material to the substrate. The substrate is positioned between layers of a thermally reflective material. Heat and pressure is applied to the substrate and thermally reflective material to reflow the pattern of hydrophobic material. A protective coating is applied over a portion of the substrate to form the fluid testing device.
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公开(公告)号:US20220062911A1
公开(公告)日:2022-03-03
申请号:US17008621
申请日:2020-08-31
Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
Inventor: Jaione Tirapu Azpiroz , Matheus Esteves Ferreira , Ademir Ferreira da Silva , Daniel Vitor Lopes Marcondes Marçal , Ricardo Luis Ohta , Mathias B. Steiner
Abstract: A multiplexed testing strip testing device includes a hydrophobic paper-based strip housing element configured for placement of one or more testing strips. One or more alignment markers on the hydrophobic paper-based housing element are marked to facilitate placement of the one or more testing strips. A cover element is arranged above the strip housing element and includes a machine-readable test identifier on an upper surface. A removably attached filtering element is arranged on the hydrophobic paper-based strip housing element.
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公开(公告)号:US11216768B2
公开(公告)日:2022-01-04
申请号:US16887607
申请日:2020-05-29
Applicant: International Business Machines Corporation
Inventor: Paulo Rodrigo Cavalin , Carmen Nilda Mena Paz , Jaione Tirapu Azpiroz , Ana Paula Appel , Alexandre Alves
Abstract: A product quality analysis and control system is provided. The product quality analysis and control system includes a processing system that is configured to receive data of objective qualities of a product from multiple data gathering modules. Each of the multiple data gathering modules is respectively positioned at corresponding nodes of a supply chain and is configured to receive from sensors data of objective qualities of a product when the product is at each of the corresponding nodes. The processing system includes a model repository and a data evaluation module. The data evaluation module is configured to select, from the model repository, a model associated with a type of the product and to use the model to analyze the data to identify changes in the objective qualities along the supply chain.
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公开(公告)号:US20210129133A1
公开(公告)日:2021-05-06
申请号:US16671284
申请日:2019-11-01
Applicant: International Business Machines Corporation
Inventor: Ricardo L. Ohta , Jaione Tirapu Azpiroz , Ademir F. Silva , Matheus Esteves Ferreira , Mathias B. Steiner
Abstract: Method, apparatus, and computer program product are provided for anonymized diagnosis using lateral flow assays. In some embodiments, a test card includes one or more lateral flow assay (LFA) with one or more test patterns (e.g., full line, partial line, dot), one or more dummy patterns, and one or more control patterns. To visually encode LFA results, at manufacture, one or more lines/dots containing true results of the LFA(s) each has a position mixed with other “dummy” lines/dots, in randomized position patterns selected from among a plurality of possible position patterns. An optical machine-readable representation of data (e.g., QR code) is attached to the test card and encodes test card identification information (e.g., lot number, serial number, test type) associated with the test card. In some embodiments, a passcode card having a scrapeable coating that conceals a passcode associated with the test card is removably attached to the test card.
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公开(公告)号:US20200282395A1
公开(公告)日:2020-09-10
申请号:US16293262
申请日:2019-03-05
Applicant: International Business Machines Corporation
Inventor: Jaione Tirapu Azpiroz , Matheus Esteves Ferreira , Ademir Ferreira da Silva , Ricardo Luis Ohta , Mathias Steiner
IPC: B01L3/00
Abstract: Fabricating a fluid testing device includes receiving a substrate, and applying a pattern of hydrophobic material to the substrate. The substrate is positioned between layers of a thermally reflective material. Heat and pressure is applied to the substrate and thermally reflective material to reflow the pattern of hydrophobic material. A protective coating is applied over a portion of the substrate to form the fluid testing device.
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公开(公告)号:US10235489B2
公开(公告)日:2019-03-19
申请号:US15800508
申请日:2017-11-01
Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
Inventor: Jaione Tirapu Azpiroz , Peter W. Bryant , Rodrigo N. B. Ferreira , Bruno D. C. Flach , Ronaldo Giro , Ricardo L. Ohta
Abstract: Methods and systems for fabricating micro-fluidic devices include determining a target cost function value based device design parameters. The performance of one or more chosen design candidates is simulated in a selected simulation model. A design candidate is identified with a cost function value closest to the target cost function value as a best initial design candidate. Design parameters of the best initial design candidate are iteratively modified to provide a modified design candidate having design parameters differing from the design parameters of the best initial design candidate, a cost function value is iteratively calculated for the modified initial design candidate, and optimized device design parameters are iteratively derived from a modified design candidate, until a computed cost function value for the modified design candidate meets the determined target cost function value. An optimized micro-fluidic device is fabricated using the modified design candidate and the optimized device design parameters.
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公开(公告)号:US20180275056A1
公开(公告)日:2018-09-27
申请号:US15469007
申请日:2017-03-24
Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
Inventor: Michael Engel , Jeannette M. Garcia , Ricardo L. Ohta , Ademir F. Silva , Mathias B. Steiner , Jaione Tirapu Azpiroz , Thomas G. Zimmerman
CPC classification number: G01N21/645 , G01N21/643 , G01N21/6452 , G01N2021/0118 , G01N2021/7793 , G01N2201/0221
Abstract: A portable optical measurement system is provided for performing metal trace analysis on a liquid sample. The system includes a sample holder for holding an analysis substrate that includes the liquid sample during the metal trace analysis. The system further includes an ultraviolet (UV) light source for emitting ultraviolet light illuminating the liquid sample. The system also includes an optical sensor for detecting radiation emanating from the liquid sample and converting the detected radiation into an electrical signal. The system additionally includes a microcontroller for processing the electrical signal. The system further includes an external interface for transmitting the processed electrical signal to an external device.
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公开(公告)号:US10071375B2
公开(公告)日:2018-09-11
申请号:US15277889
申请日:2016-09-27
Applicant: International Business Machines Corporation
Inventor: Jaione Tirapu Azpiroz , Peter William Bryant , Rodrigo Neumann Barros Ferreira , Ronaldo Giro , Ricardo Luis Ohta
CPC classification number: B01L3/502746 , B01L3/502707 , B01L3/502715 , B01L3/502761 , B01L2200/06 , B01L2200/0652 , B01L2200/0668 , B01L2200/12 , B01L2300/0645 , B01L2300/123 , B01L2400/0661 , B01L2400/082 , B01L2400/086 , B81B1/006 , B81B2201/058 , B81B2203/0361 , B81C1/00111 , F16B1/0014
Abstract: A microfluidic device, including a substrate including a microchannel, an activation setup disposed in the microchannel, and a matrix array of controllable shape-changing micropillars connected to the activation setup. A shape of the controllable shape-changing micropillars changes based on an activation of the activation setup.
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公开(公告)号:US20180151668A1
公开(公告)日:2018-05-31
申请号:US15362191
申请日:2016-11-28
Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
Inventor: Michael Engel , Mathias B. Steiner , Jaione Tirapu Azpiroz
CPC classification number: H01L21/02376 , B82Y40/00 , H01L51/0023 , H01L51/0045 , H01L51/0048 , H01L51/102 , Y10S977/742
Abstract: A method of positioning nanomaterials that includes forming a set of electrodes on a substrate, and covering the electrodes and substrate with a single layer of guiding dielectric material. The method may continue with patterning the guiding dielectric to provide dielectric guide features, wherein an exposed portion of the substrate between the dielectric guide features provides a deposition surface. A liquid medium containing at least one nanostructure is applied to the guiding dielectric features and the deposition surface. An electric field produced by the electrodes that is attenuated by the dielectric guide features creates an attractive force that guides the nanostructures to the deposition surface.
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