公开(公告)号：US07244439B2

公开(公告)日：2007-07-17

申请号：US10410237

申请日：2003-04-10

申请人： Yuko Yago ,  Keisuke Nakao ,  Ryuji Hasegawa ,  Noboru Nagatani ,  Keiichi Fukuda ,  Naoki Nojiri ,  Hidetake Nakamura ,  Hideaki Kubo

发明人： Yuko Yago ,  Keisuke Nakao ,  Ryuji Hasegawa ,  Noboru Nagatani ,  Keiichi Fukuda ,  Naoki Nojiri ,  Hidetake Nakamura ,  Hideaki Kubo

IPC分类号： A61K6/00 ,  A61K9/14 ,  A61K9/16

CPC分类号： A61K8/0254 ,  A61K8/19 ,  A61K8/29 ,  A61K2800/412 ,  A61K2800/61 ,  A61Q1/00 ,  A61Q1/12

摘要： A cosmetic composition having excellent application feeling and transparency while maintaining covering power which includes (a) composite particles obtained by allowing at least two kinds of particles having different shapes and particle diameters to contact with at least one polymer compound selected from the group consisting of fluorinated polymer compounds, silicone polymer compounds, and mixture thereof, in the presence of supercritical carbon dioxide, and (b) a cosmetic component.

摘要翻译： 一种具有优异的使用感和透明度同时保持覆盖力的化妆品组合物，其包括（a）通过使至少两种具有不同形状和粒径的颗粒与至少一种选自以下的聚合物化合物接触而获得的复合颗粒：氟化 聚合物化合物，硅氧烷聚合物化合物及其混合物，在超临界二氧化碳的存在下，和（b）化妆品组分。

公开(公告)号：US20060104942A1

公开(公告)日：2006-05-18

申请号：US11316890

申请日：2005-12-27

申请人： Keiichi Fukuda ,  Yasuyo Hisaka ,  Tatsuya Miyai ,  Masahiko Tamura

发明人： Keiichi Fukuda ,  Yasuyo Hisaka ,  Tatsuya Miyai ,  Masahiko Tamura

IPC分类号： A61K38/19

CPC分类号： A61K9/0019 ,  A61K31/663 ,  A61K38/193 ,  A61K47/02 ,  A61K47/26

摘要： An effective remedy for ischemic disease, which contains human granulocyte colony-stimulating factor (human G-CSF) and hepatocyte growth factor (HGF) as active ingredients, is disclosed. By administering this remedy, an effective therapy particularly for obstructive arteriosclerosis is provided which can eliminate drawbacks with conventional therapies such as kinesitherapy, pharmacotherapy, revascularization and recently proposed therapies such as gene therapy and intramuscular inoculation of bone marrow cells. Furthermore, the remedy of the present invention can become a remedy for ischemic disease such as ischemic cerebrovascular disorder or ischemic heart disease.

公开(公告)号：US5674954A

公开(公告)日：1997-10-07

申请号：US470474

申请日：1995-06-06

申请人： Seiichi Masuko ,  Ichisaburo Nakamura ,  Yoshimatsu Naka ,  Keiichi Fukuda ,  Akira Yamamoto ,  Yasuyuki Hatakeyama

发明人： Seiichi Masuko ,  Ichisaburo Nakamura ,  Yoshimatsu Naka ,  Keiichi Fukuda ,  Akira Yamamoto ,  Yasuyuki Hatakeyama

IPC分类号： C08F2/00 ,  C08F14/06 ,  C08F2/20

CPC分类号： C08F14/06 ,  C08F2/004

摘要： In a novel method of homo- or copolymerization of vinyl chloride, a specified coating agent is applied on the surfaces of the portions which will become into contact with the vinyl chloride monomer during the polymerization process. The coating agent is in a form of an aqueous solution of a modified condensation product of phenol and aldehyde, the pH of the solution being adjusted in a range that the product is dissolved at an ambient temperature upon coating of the solution and separates out of the solution upon being heated on the surfaces. The wall surface of the polymerization tank and the like is then coated with a thin film of the coating agent having a uniform thickness and being strongly adhered to the wall surface, thereby providing an excellent effect of preventing adhesion of the product polymer to the wall surface.

摘要翻译： 在氯乙烯均聚或共聚的新方法中，在聚合过程中将在与氯乙烯单体接触的部分的表面上施加特定的涂布剂。 涂层剂是苯酚和醛的改性缩合产物的水溶液形式，溶液的pH值在产物在环境温度下溶解的范围内被调节，并在分离出 在表面上加热时的溶液。 然后将聚合槽等的壁面用均匀厚度的涂布剂的薄膜涂布并牢固地附着在壁面上，从而提供优异的防止产品聚合物粘合到壁面上的效果 。

公开(公告)号：US09096720B2

公开(公告)日：2015-08-04

申请号：US13579335

申请日：2011-02-10

申请人： Kouki Fukumura ,  Hironori Kuboi ,  Keiichi Fukuda

发明人： Kouki Fukumura ,  Hironori Kuboi ,  Keiichi Fukuda

IPC分类号： C08G69/08 ,  C08G69/48 ,  C07C229/22 ,  C08G73/10

CPC分类号： C08G73/1092

摘要： Disclosed are a method for producing a polyaspartic acid precursor polymer by polymerization using at least one kind selected from a product obtained from maleic anhydride and ammonia and, maleamic acid as a monomer, wherein at least part of carboxyl groups in the monomers are a tertiary amine salt; and an industrially inexpensive and simple method for producing a polyaspartic acid salt by treating the polyaspartic acid precursor polymer obtained by this method with a basic aqueous solution.

摘要翻译： 公开了通过使用选自马来酸酐和氨的马来酰胺酸和马来酰胺酸作为单体中的至少一种的聚合制备聚天冬氨酸前体聚合物的方法，其中单体中的至少部分羧基是叔胺 盐; 以及通过用碱性水溶液处理通过该方法得到的聚天冬氨酸前体聚合物来制造聚天冬氨酸盐的工业上便宜且简单的方法。

公开(公告)号：US20130062338A1

公开(公告)日：2013-03-14

申请号：US13640256

申请日：2011-04-06

申请人： Kenji Iida ,  Daisaku Seki ,  Akira Sasaki ,  Yoshiyuki Motoyoshi ,  Mitsushi Wadasako ,  Keiichi Fukuda

发明人： Kenji Iida ,  Daisaku Seki ,  Akira Sasaki ,  Yoshiyuki Motoyoshi ,  Mitsushi Wadasako ,  Keiichi Fukuda

IPC分类号： H05B3/12 ,  H05B3/02

CPC分类号： H05B3/12 ,  F16L53/38 ,  H05B3/02 ,  H05B3/34 ,  H05B3/56 ,  H05B3/58 ,  Y10T29/49002

摘要： The present invention relates to a jacket heater having a heating element built therein, the jacket heater containing: the heating element having a watt density of 0.15 W/cm2 or more, a metal foil disposed adjacently to the heating element, and a surrounding body which surrounds the heating element and the metal foil.

摘要翻译： 本发明涉及一种具有内置加热元件的护套加热器，该夹套加热器包括：瓦特密度为0.15W / cm 2以上的加热元件，与该加热元件相邻设置的金属箔，以及周围体， 围绕加热元件和金属箔。

公开(公告)号：US20120227251A1

公开(公告)日：2012-09-13

申请号：US13508989

申请日：2011-07-21

申请人： Shunta Hyuga ,  Norio Suzuki ,  Keiichi Fukuda ,  Haruaki Miyamura

发明人： Shunta Hyuga ,  Norio Suzuki ,  Keiichi Fukuda ,  Haruaki Miyamura

IPC分类号： H01H11/00

CPC分类号： H01H13/88 ,  B29C45/14467 ,  B29K2083/005 ,  H01H13/063 ,  H01H2223/002 ,  H01H2229/044 ,  H01H2229/048

摘要： In a manufacturing method of a push-button switch, a key-top end of a pressing element 25 is inserted into a lower-mold recess for the pressing element, which is provided in a surface of a lower mold. A reinforcing plate 28 is placed in the lower mold so that the pressing element 25 extends through a plate through hole of the reinforcing plate 28. An upper mold and the lower mold are moved toward each other so as to insert the other end of the pressing element 25 into an upper-mold recess for the pressing element, which is provided in a lower surface of the upper mold. A liquid silicone rubber 27, which contains a component that does not adhere to the upper and lower molds but adheres to the pressing element 25, is introduced into a cavity. After the upper and lower molds are pressed and held at a predetermined temperature for a predetermined time, the upper and lower molds are opened to remove a molded product in which an intermediate portion in an axial direction of the pressing element 25 is supported in the plate through hole by the silicone rubber 27. A back surface of a key top 26 is attached to the key-top end of the pressing element 25 in the molded product. Thus, the pressing element and the elastic member are easily and reliably integrally molded by using the elastic member, and durability of the push-button switch is improved.

摘要翻译： 在按钮开关的制造方法中，按压元件25的键顶端插入到设置在下模的表面中的用于按压元件的下模凹部中。 加强板28放置在下模具中，使得按压元件25延伸穿过加强板28的板通孔。上模和下模彼此移动，以将另一端插入 元件25设置在上模具的下表面中的用于按压元件的上模凹槽中。 含有不粘附到上模具和下模具但粘附到按压元件25上的部件的液体硅橡胶27被引入空腔中。 在上模和下模被按压并在预定温度下保持预定时间之后，打开上下模具以移除模制产品，其中按压元件25的轴向中间部分被支撑在板 通过硅橡胶27的通孔。键顶26的后表面附接到模制产品中的按压元件25的键顶端。 因此，通过使用弹性构件，按压元件和弹性构件容易且可靠地一体地模制，并且提高了按钮开关的耐久性。

公开(公告)号：US20120094383A1

公开(公告)日：2012-04-19

申请号：US13260224

申请日：2010-03-29

申请人： Fumiyuki Hattori ,  Keiichi Fukuda

发明人： Fumiyuki Hattori ,  Keiichi Fukuda

IPC分类号： C12N5/077

CPC分类号： C12N5/0657 ,  C12N5/0081 ,  C12N5/0696 ,  C12N2501/90 ,  C12N2506/02

摘要： The present invention has as its object developing a method that does not involve genomic modification and which yet is capable of inducing cell death in pluripotent stem cells such as embryonic stem cells and induced pluripotent stem cells, as well as in differentiated cells other than cardiomyocytes derived from pluripotent stem cells, but not in cardiomyocytes. It has been revealed that by establishing a method capable of inducing cell death in cells other than cardiomyocytes in a very efficient manner by adding a substance having no recognized inherent toxicity or cell death inducing action to the culture conditions for pluripotent stem cells and non-cardiomyocytes, the stated problem can be solved without relying upon genomic modification.

摘要翻译： 本发明的目的是开发一种不涉及基因组修饰并且能够在多能干细胞如胚胎干细胞和诱导的多能干细胞以及除了心肌细胞以外的分化细胞中诱导细胞死亡的方法 来自多能干细胞，但不在心肌细胞中。 已经揭示出，通过向多能干细胞和非心肌细胞的培养条件中加入不具有公认的固有毒性或细胞死亡诱导作用的物质，通过建立能够以非常有效的方式在除心肌细胞之外的细胞中诱导细胞死亡的方法 所述问题可以解决而不依赖于基因组修饰。

公开(公告)号：US08014126B2

公开(公告)日：2011-09-06

申请号：US11922697

申请日：2006-06-23

申请人： Shigeki Sato ,  Keiichi Fukuda

发明人： Shigeki Sato ,  Keiichi Fukuda

IPC分类号： H01G4/06

CPC分类号： H01G4/1227 ,  B82Y30/00 ,  C04B35/4686 ,  C04B35/6264 ,  C04B35/63424 ,  C04B35/638 ,  C04B2235/3206 ,  C04B2235/3208 ,  C04B2235/3213 ,  C04B2235/3224 ,  C04B2235/3225 ,  C04B2235/3241 ,  C04B2235/3262 ,  C04B2235/3272 ,  C04B2235/3275 ,  C04B2235/3279 ,  C04B2235/3418 ,  C04B2235/3436 ,  C04B2235/36 ,  C04B2235/5445 ,  C04B2235/5454 ,  C04B2235/6025 ,  C04B2235/656 ,  C04B2235/6562 ,  C04B2235/6567 ,  C04B2235/6582 ,  C04B2235/6584 ,  C04B2235/663 ,  C04B2235/79 ,  H01B3/12 ,  H01G4/30

摘要： Electronic device 1 comprises an element body 10, comprising a dielectric layer 2 constituted by a dielectric ceramic composition, and a terminal electrode 4, formed outside of the element body 10. The dielectric ceramic composition comprised a main component including barium titanate; a first subcomponent including at least one oxide of Mg and Ca; a second subcomponent including SiO2; a third subcomponent including at least one oxide of Mn and Cr; and a fourth subcomponent including an oxide of rare earth elements, wherein the net valence of Mn and/or Cr in the third subcomponent is 2.2 to 2.4. According to the electronic device 1, both high temperature accelerated lifetime characteristics and capacity stress aging characteristics can be improved in a balanced manner.

摘要翻译： 电子设备1包括元件体10，其包括由电介质陶瓷组合物构成的电介质层2和形成在元件主体10的外部的端子电极4.该介电陶瓷组合物包括包含钛酸钡的主要成分; 包含Mg和Ca的至少一种氧化物的第一副成分; 第二个次要组分包括SiO2; 包含至少一种Mn和Cr的氧化物的第三副成分; 以及包含稀土元素氧化物的第四副成分，其中第三副成分中Mn和/或Cr的净价为2.2〜2.4。 根据电子设备1，可以以均衡的方式提高高温加速寿命特性和容量应力老化特性。

公开(公告)号：US20110026548A1

公开(公告)日：2011-02-03

申请号：US12921822

申请日：2008-03-18

申请人： Motoaki Tamaya ,  Chise Nanba ,  Akira Nakamura ,  Keiichi Fukuda ,  Koji Funaoka ,  Manabu Kawakami ,  Masamitsu Okamura

发明人： Motoaki Tamaya ,  Chise Nanba ,  Akira Nakamura ,  Keiichi Fukuda ,  Koji Funaoka ,  Manabu Kawakami ,  Masamitsu Okamura

IPC分类号： H01S3/10 ,  H01S3/04

CPC分类号： H01S3/025 ,  G02F1/37 ,  H01S3/0092 ,  H01S3/042 ,  H01S3/09415

摘要： When a laser light source module includes a heat sink in which a solid laser element, an excitation light source, and a wavelength conversion element are arranged and a stem that supports the heat sink, wherein the heat sink is separated into three blocks, namely a first block including a laser oscillating unit for the solid laser element is arranged, a second block including a semiconductor laser element that emits excitation light for the laser oscillating unit and a first temperature sensor are arranged and on a specific surface of which the first heater is arranged, and a third block including the wavelength conversion element that converts the wavelength of the fundamental laser beam and a second temperature sensor are arranged and on a specific surface of which a second heater is arranged, enabling thus downsizing of the module and improvement of the positioning accuracy of the elements.

摘要翻译： 当激光光源模块包括其中布置有固体激光元件，激发光源和波长转换元件的散热器和支撑散热器的灯杆时，其中散热器被分成三块，即 布置包括用于固体激光元件的激光振荡单元的第一块，布置包括发射用于激光振荡单元的激发光的半导体激光元件的第二块和第一温度传感器，并且其特定表面上的第一加热器 并且配置有包括转换基波激光束的波长的波长转换元件和第二温度传感器的第三块，并且在其特定表面上布置有第二加热器，从而能够实现模块的小型化和改进 元素的定位精度。

公开(公告)号：US20100260226A1

公开(公告)日：2010-10-14

申请号：US12740055

申请日：2007-12-21

申请人： Motoaki Tamaya ,  Keiichi Fukuda ,  Shinichi Oe ,  Chise Nanba ,  Akira Nakamura

发明人： Motoaki Tamaya ,  Keiichi Fukuda ,  Shinichi Oe ,  Chise Nanba ,  Akira Nakamura

IPC分类号： H01S5/42

CPC分类号： H01S5/02276 ,  H01L2224/48091 ,  H01L2224/49175 ,  H01S5/0224 ,  H01S5/02272 ,  H01S5/02492 ,  H01S5/4031 ,  H01L2924/00014

摘要： A heat sink is made of a material excellent in thermal conductivity and is mounted on a stem; a sub-mount substrate is made of a material excellent in insulation property and is mounted on the heat sink; a first lead frame made of a material excellent in electric conductivity and thermal conductivity and having a linear expansion coefficient similar to that of a semiconductor laser array, is mounted on the sub-mount substrate, having the semiconductor laser array mounted thereon, and composing a power feeding path of the semiconductor laser array; a second lead frame made of a material excellent in electric conductivity and thermal conductivity, is arranged on the sub-mount substrate side by side with the first lead frame, and composing the power feeding path of the semiconductor laser array; and a wire electrically bonds the semiconductor laser array and the second lead frame.

摘要翻译： 散热器由导热性优异的材料制成，并安装在杆上; 副安装基板由绝缘性优异的材料制成，并安装在散热片上; 由导电性和导热性优异的材料制成的具有类似于半导体激光器阵列的线性膨胀系数的第一引线框安装在安装有半导体激光器阵列的子安装基板上，并组成 半导体激光器阵列的馈电路径; 由导电性和导热性优异的材料构成的第二引线框架与第一引线框并排配置在副安装基板上，构成半导体激光器阵列的馈电路径; 并且导线将半导体激光器阵列和第二引线框架电连接。