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公开(公告)号:US11821554B2
公开(公告)日:2023-11-21
申请号:US17712501
申请日:2022-04-04
Applicant: Life Technologies Corporation
Inventor: Ryan S. Beus , Brandon R. Burtenshaw , Eric Davis , Patrick L. Draper , Michael E. Goodwin , Brandon M. Knudsen , Jeremy K. Larsen , Kevin R. Pickup
CPC classification number: F16L33/207 , A61M39/12 , B29C65/565 , B29C65/68 , B29C66/1122 , B29C66/12 , B29C66/1222 , B29C66/1224 , B29C66/131 , B29C66/30321 , B29C66/5344 , B29C66/7315 , B29C66/7392 , B29C66/7394 , B29C66/73753 , F16L33/227 , B29C66/71 , B29L2031/24 , B29C66/71 , B29K2023/06 , B29C66/71 , B29K2023/065
Abstract: A coupling assembly includes: a tubular compression collar having a tubular body made of a resiliently flexible polymeric material and having an interior surface and an opposing exterior surface; an end of a tube disposed within a throughway of the compression collar; and a tube fitting disposed within the passageway of the tube. The tube fitting includes: a tubular stem; a flange radially outwardly projecting from an exterior surface of the stem; and an annular barb encircling and radially outwardly projecting from the exterior surface of the stem, the annular barb including a frustoconical outside face that extends along and outwardly slopes away from the stem as the outside face extends toward the flange. The compression collar radially inwardly compresses the tube against the annular barb of the tube fitting so that a liquid tight seal is formed between the tube and the tube fitting.
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公开(公告)号:US11639240B2
公开(公告)日:2023-05-02
申请号:US17481605
申请日:2021-09-22
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Michael E. Goodwin , Jeremy K. Larsen , Patrick L. Draper , Brandon M. Knudsen
Abstract: A fluid manifold system includes a first manifold having portions of opposing flexible sheets welded together to form a fluid flow path therebetween, a fluid inlet communicating with the fluid flow path. The fluid flow path of the first manifold includes: a primary flow path communicating with the fluid inlet of the first manifold; and a plurality of spaced apart secondary flow paths that branch off of the primary flow path. Each secondary flow path has a first end communicating with the primary flow path and an opposing second end, each secondary flow path having a diameter that is smaller than a diameter of the primary flow path. The fluid manifold system also includes a plurality of tubular connectors with each tubular connector being secured to the first manifold at the second end of a corresponding one of the secondary flow paths.
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公开(公告)号:US20190054433A1
公开(公告)日:2019-02-21
申请号:US16165650
申请日:2018-10-19
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Jeremy K. Larsen , Clinton C. Staheli , Brandon M. Knudsen
Abstract: A fluid mixing system includes a flexible bag having a first end, an opposing second end, and an interior surface bounding a compartment. A first rotational assembly includes a first casing mounted to the first end of the flexible bag and a first hub rotatably mounted to the first casing. A second rotational assembly includes a second casing mounted to the second end of the flexible bag and a second hub rotatably mounted to the second casing. An elongated member has a first end coupled with the first hub and an opposing second end coupled with the second hub, the connector being flexible and having a uniform flexibility along its entire length. A first impeller is mounted to the connector.
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公开(公告)号:US20180187809A1
公开(公告)日:2018-07-05
申请号:US15863031
申请日:2018-01-05
Applicant: Life Technologies Corporation
Inventor: Ryan S. Beus , Brandon R. Burtenshaw , Eric Davis , Patrick L. Draper , Michael E. Goodwin , Brandon M. Knudsen , Jeremy K. Larsen , Kevin R. Pickup
IPC: F16L33/207 , F16L33/22
Abstract: A method for coupling a tube to a tube fitting includes radially outwardly expanding a tubular compression collar from a constricted state to an expanded state, the compression collar having a throughway extending there through and being made of a resiliently flexible material. An end of the tube is inserted within the throughway of the expanded compression collar, the tube bounding a passageway. A tube fitting is inserted within the passageway of the tube. The compression collar is allowed to resiliently rebound back towards the constricted state so that the compression collar pushes the tube against the tube fitting.
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公开(公告)号:US09700857B1
公开(公告)日:2017-07-11
申请号:US13849361
申请日:2013-03-22
Applicant: Life Technologies Corporation
Inventor: Jeremy K. Larsen , Clinton C. Staheli , Brandon M. Knudsen
CPC classification number: B01F7/00691 , B01F7/00633 , B01F7/00725 , B01F7/16 , B01F7/1695 , B01F7/22 , B01F15/00006 , B01F15/00441 , B01F15/00454 , B01F15/00662 , B01F15/00668 , B01F15/00688 , B01F15/00707 , B01F15/0085 , B01F15/00857 , B01F2015/00649
Abstract: A fluid mixing system includes a flexible bag having an interior surface bounding a compartment. A retainer is coupled to the flexible bag, the retainer having a retention cavity formed thereon that communicates with the compartment of the flexible bag. An elongated tubular connector has a first end coupled to the flexible bag and an opposing second end projecting into the compartment thereof. An impeller is disposed within flexible bag and is coupled with the tubular connector. A steady support is mounted on the second end of the tubular connector and terminates at a distal nose, the distal nose being freely disposed within the retention cavity of the retainer so that the steady support can rotate within the retention cavity relative to the retainer.
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公开(公告)号:US20150138913A1
公开(公告)日:2015-05-21
申请号:US14405126
申请日:2013-02-26
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Nephi D. Jones , Brandon M. Knudsen , Whitt F. Woods
CPC classification number: B01F15/0085 , B01F7/001 , B01F7/00725 , B01F7/1615 , B01F7/1695 , B01F7/22 , B01F11/0008 , B01F11/0017 , B01F15/00733 , B01F15/0074 , B01F15/00772 , B01F15/0203 , B01F15/0295 , B01F2015/0221 , C12M23/14 , C12M23/48 , C12M23/52 , C12M27/00 , C12M27/02 , C12M27/16 , C12M29/06
Abstract: A fluid mixing system that can be used as a bioreactor or fermentor can include a stand and a support housing pivotably mounted to the stand. The support housing bounds a chamber into which a container assembly is removably disposed. The container assembly includes a flexible bag bounding a compartment adapted to hold a fluid and a mixing element disposed within the compartment. The support housing can be tilted relative to the stand for ease in insertion of the container assembly. The support housing can also be repeatedly rocked relative to the stand form mixing fluid within the container assembly.
Abstract translation: 可用作生物反应器或发酵罐的流体混合系统可以包括支架和可枢转地安装在支架上的支撑壳体。 支撑壳体限定容器组件可移除地设置在其中的室。 容器组件包括柔性袋,其包围适于保持流体的室和设置在室内的混合元件。 支撑壳体可以相对于支架倾斜,以便于容器组件的插入。 支撑壳体也可以相对于在容器组件内混合流体的支架形式重复摇动。
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公开(公告)号:US12128371B2
公开(公告)日:2024-10-29
申请号:US16358263
申请日:2019-03-19
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Clinton C. Staheli , Brandon M. Knudsen , Trevor G. Williams , Steven R. Kjar
IPC: B01F27/054 , B01F27/07 , B01F27/072 , B01F27/1125 , B01F27/191 , B01F27/21 , B01F27/2111 , B01F27/88 , B01F27/906 , B01F35/41 , B01F35/513 , C12M1/00 , C12M1/06
CPC classification number: B01F27/212 , B01F27/0541 , B01F27/071 , B01F27/0726 , B01F27/1125 , B01F27/11253 , B01F27/191 , B01F27/2111 , B01F27/88 , B01F27/906 , B01F35/41 , B01F35/4111 , B01F35/4121 , B01F35/513 , C12M23/14 , C12M23/52 , C12M27/02
Abstract: A fluid mixing system includes a container, such as a flexible bag, bounding a compartment. A flexible drive line is disposed within the compartment, the drive line having a first end rotatably connected to a first end of the container and an opposing second end rotatably connected to a second end of the container. At least one mixing element, such as an impeller, can be coupled with the flexible drive line. Rotation of the drive line facilitates rotation of the impeller within the container.
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公开(公告)号:US20240342670A1
公开(公告)日:2024-10-17
申请号:US18754057
申请日:2024-06-25
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Jeremy K. Larsen , Clinton C. Staheli , Brandon M. Knudsen
IPC: B01F27/2121 , B01F27/191 , B01F27/213 , B01F27/80 , B01F27/88 , B01F27/91 , B01F33/00 , B01F35/31 , B01F35/32 , B01F35/40 , B01F35/41 , B01F35/50 , B01F35/513
CPC classification number: B01F27/2121 , B01F27/191 , B01F27/213 , B01F27/88 , B01F27/91 , B01F33/86 , B01F35/322 , B01F35/3231 , B01F35/40 , B01F35/4121 , B01F35/513 , B01F27/80 , B01F35/31 , B01F35/41 , B01F35/4112 , B01F35/514
Abstract: The present disclosure relates to a mixing assembly for a fluid mixing system. The mixing assembly includes a first rotational assembly having a first casing and a first hub rotatably mounted to the first casing, a second rotational assembly having a second casing and a second hub rotatably mounted to the second casing, an elongated member having a first end coupled with the first hub and an opposing second end coupled with the second hub, and one or more impellers secured to the elongated member.
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公开(公告)号:US20240044430A1
公开(公告)日:2024-02-08
申请号:US18485155
申请日:2023-10-11
Applicant: Life Technologies Corporation
Inventor: Ryan S. Beus , Brandon R. Burtenshaw , Eric Davis , Patrick L. Draper , Michael E. Goodwin , Brandon M. Knudsen , Jeremy K. Larsen , Kevin R. Pickup
CPC classification number: F16L33/207 , F16L33/227 , B29C66/131 , B29C66/73753 , B29C65/68 , B29C65/565 , B29C66/1224 , A61M39/12 , B29C66/7392 , B29C66/5344 , B29C66/1222 , B29C66/12 , B29C66/7394 , B29C66/30321 , B29C66/7315 , B29C66/1122 , B29L2031/24
Abstract: A coupling assembly includes: a tubular compression collar having a tubular body made of a resiliently flexible polymeric material and having an interior surface and an opposing exterior surface; an end of a tube disposed within a throughway of the compression collar; and a tube fitting disposed within the passageway of the tube. The tube fitting includes: a tubular stem; a flange radially outwardly projecting from an exterior surface of the stem; and an annular barb encircling and radially outwardly projecting from the exterior surface of the stem, the annular barb including a frustoconical outside face that extends along and outwardly slopes away from the stem as the outside face extends toward the flange. The compression collar radially inwardly compresses the tube against the annular barb of the tube fitting so that a liquid tight seal is formed between the tube and the tube fitting.
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公开(公告)号:US20230234732A1
公开(公告)日:2023-07-27
申请号:US18189994
申请日:2023-03-24
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor: Michael E. Goodwin , Jeremy K. Larsen , Patrick L. Draper , Brandon M. Knudsen
CPC classification number: B65B1/04 , B65B3/003 , B65B3/02 , B65B3/04 , B65B51/02 , B65B51/225 , A61J1/10
Abstract: A fluid manifold system includes a first manifold having portions of opposing flexible sheets welded together to form a fluid flow path therebetween, a fluid inlet communicating with the fluid flow path. The fluid flow path of the first manifold includes: a primary flow path communicating with the fluid inlet of the first manifold; and a plurality of spaced apart secondary flow paths that branch off of the primary flow path. Each secondary flow path has a first end communicating with the primary flow path and an opposing second end, each secondary flow path having a diameter that is smaller than a diameter of the primary flow path. The fluid manifold system also includes a plurality of tubular connectors with each tubular connector being secured to the first manifold at the second end of a corresponding one of the secondary flow paths.
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