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公开(公告)号：US11371634B2
公开(公告)日：2022-06-28
申请号：US15863031
申请日：2018-01-05
Applicant: Life Technologies Corporation
Inventor： Ryan S. Beus , Brandon R. Burtenshaw , Eric Davis , Patrick L. Draper , Michael E. Goodwin , Brandon M. Knudsen , Jeremy K. Larsen , Kevin R. Pickup
Abstract: A method for coupling a tube to a tube fitting includes radially outwardly expanding a tubular compression collar from a constricted state to an expanded state, the compression collar having a throughway extending there through and being made of a resiliently flexible material. An end of the tube is inserted within the throughway of the expanded compression collar, the tube bounding a passageway. A tube fitting is inserted within the passageway of the tube. The compression collar is allowed to resiliently rebound back towards the constricted state so that the compression collar pushes the tube against the tube fitting.
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公开(公告)号：US20210077960A1
公开(公告)日：2021-03-18
申请号：US17105810
申请日：2020-11-27
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Jeremy K. Larsen , Clinton C. Staheli , Brandon M. Knudsen
Abstract: A fluid mixing system includes a flexible bag having a first end, an opposing second end, and an interior surface bounding a compartment; a retainer coupled to the second end of the flexible bag, the retainer having a retention cavity formed thereon that communicates with the compartment of the flexible bag; and an elongated member having a first end rotatably coupled to the first end of the flexible bag and an opposing second end freely disposed within the retention cavity of the retainer so that the second end of the elongated member can rotate within the retention cavity relative to the retainer.
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公开(公告)号：US20200255780A1
公开(公告)日：2020-08-13
申请号：US16863702
申请日：2020-04-30
Applicant: LIFE TECHNOLOGIES CORPORATION , Baxalta Incorporated , BAXALTA GMBH
Inventor： Kurt T. Kunas , Robert V. Oakley , Fauad F. Hasan , Michael E. Goodwin , Jeremy K. Larsen , Nephi D. Jones
Abstract: A reactor system includes a support housing having an interior surface bounding a chamber, the chamber having a vertically extending central longitudinal axis. A flexible bag is disposed within the chamber of the support housing and has an interior surface bounding a compartment. A mixing element is disposed within the compartment of the flexible bag. A drive element, such as a drive shaft, is secured the mixing element, wherein the mixing element is laterally offset from and/or is angled relative to the vertically extending central longitudinal axis of the support housing.
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公开(公告)号：US10118141B2
公开(公告)日：2018-11-06
申请号：US15066751
申请日：2016-03-10
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Jeremy K. Larsen , Clinton C. Staheli , Brandon M. Knudsen
Abstract: A fluid mixing system includes a flexible bag having a first end, an opposing second end, and an interior surface bounding a compartment. A first rotational assembly includes a first casing mounted to the first end of the flexible bag and a first hub rotatably mounted to the first casing. A second rotational assembly includes a second casing mounted to the second end of the flexible bag and a second hub rotatably mounted to the second casing. A connector has a first end coupled with the first hub and an opposing second end coupled with the second hub, the connector being flexible and having a uniform flexibility along its entire length. A first impeller is mounted to the connector.
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公开(公告)号：US20160304825A1
公开(公告)日：2016-10-20
申请号：US15193962
申请日：2016-06-27
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Jeremy K. Larsen , Jon Q. Coleman , David S. Rowley
IPC: C12M1/00 , B01D29/13 , B01D35/027 , C12M1/12 , C12M1/26
CPC classification number: C12M29/04 , B01D29/13 , B01D29/27 , B01D35/027 , C12M23/14 , C12M23/26 , C12M25/16 , C12M33/14 , C12M47/02
Abstract: A filter assembly for separating microcarriers from a fluid medium includes a collapsible container bounding a sterile compartment adapted to hold a fluid. An inlet port is attached to the container through which fluid flows into the compartment. An outlet port is attached to the container through which fluid flows out of the compartment. A filter is disposed within the compartment, the filter dividing the compartment into an inlet chamber that is fluidly coupled with the inlet port and an outlet chamber that is fluidly coupled with the outlet port, the filter allowing a medium to pass therethrough but preventing microcarriers disposed in the medium from passing therethrough.
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Patent Agency Ranking
公开(公告)号：US20160193576A1
公开(公告)日：2016-07-07
申请号：US15066751
申请日：2016-03-10
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Jeremy K. Larsen , Clinton C. Staheli , Brandon M. Knudsen
CPC classification number: B01F7/00691 , B01F7/00633 , B01F7/00725 , B01F7/16 , B01F7/1695 , B01F7/22 , B01F15/00006 , B01F15/00441 , B01F15/00454 , B01F15/00662 , B01F15/00668 , B01F15/00688 , B01F15/00707 , B01F15/0085 , B01F15/00857 , B01F2015/00649
Abstract: A fluid mixing system includes a flexible bag having a first end, an opposing second end, and an interior surface bounding a compartment. A first rotational assembly includes a first casing mounted to the first end of the flexible bag and a first hub rotatably mounted to the first casing. A second rotational assembly includes a second casing mounted to the second end of the flexible bag and a second hub rotatably mounted to the second casing. A connector has a first end coupled with the first hub and an opposing second end coupled with the second hub, the connector being flexible and having a uniform flexibility along its entire length. A first impeller is mounted to the connector.
Abstract translation: 流体混合系统包括具有第一端，相对的第二端和限定隔间的内表面的柔性袋。 第一旋转组件包括安装到柔性袋的第一端的第一壳体和可旋转地安装到第一壳体的第一毂。 第二旋转组件包括安装到柔性袋的第二端的第二壳体和可旋转地安装到第二壳体的第二轮毂。 连接器具有与第一轮毂相连的第一端和与第二轮毂联接的相对的第二端，该连接器是柔性的并且沿着其整个长度具有均匀的柔性。 第一叶轮安装在连接器上。
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公开(公告)号：US20160158711A1
公开(公告)日：2016-06-09
申请号：US15041335
申请日：2016-02-11
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Michael D. Goodwin , Nephi D. Jones , Jeremy K. Larsen
CPC classification number: B01F15/0085 , B01F3/04269 , B01F3/04439 , B01F3/04829 , B01F5/04 , B01F7/00341 , B01F7/22 , B01F11/0082 , B01F13/0255 , B01F2003/04276 , B01F2003/04297 , B01F2003/04312 , B01F2003/04326 , B01F2003/04361 , B01F2003/04382 , B01F2003/04397 , B01F2215/0073 , C12M23/14 , C12M23/20 , C12M23/26 , C12M27/04 , C12M29/06 , C12M37/00
Abstract: A container assembly includes a container at least partially bounding a chamber and having a wall with an opening extending therethrough. A tubular stem bounds a passageway and outwardly projects from the wall of the container so that the passageway communicates with the opening. A sparger includes a tubular member having a first end and an opposing second end and an interior surface bounding a passage extending therebetween. A gas permeable sparging member is secured to the first end of the tubular member so that gas passing through the tubular member from the second end passes out through the sparging sheet. A second flange encircles and radially outwardly projects from the tubular member, the second flange being secured to the stem so that at least a portion of the tubular member is disposed within the passageway of the tubular stem.
Abstract translation: 容器组件包括容器，该容器至少部分地限定室并具有壁，所述壁具有贯穿其中的开口。 管状茎状物限定通道并从容器的壁向外突出，使得通道与开口连通。 分布器包括具有第一端和相对的第二端的管状构件和限定在其之间延伸的通道的内表面。 气体可渗透的喷射构件被固定到管状构件的第一端，使得从第二端通过管状构件的气体通过喷射板。 第二凸缘环绕并从管状构件径向向外突出，第二凸缘固定到杆，使得管状构件的至少一部分设置在管状杆的通道内。
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公开(公告)号：US09005971B2
公开(公告)日：2015-04-14
申请号：US14094541
申请日：2013-12-02
Applicant: Life Technologies Corporation
Inventor： Michael E. Goodwin , Nephi D. Jones , Jeremy K. Larsen
CPC classification number: B01F15/0085 , B01F3/04269 , B01F3/04439 , B01F3/04829 , B01F5/04 , B01F7/00341 , B01F7/22 , B01F11/0082 , B01F13/0255 , B01F2003/04276 , B01F2003/04297 , B01F2003/04312 , B01F2003/04326 , B01F2003/04361 , B01F2003/04382 , B01F2003/04397 , B01F2215/0073 , C12M23/14 , C12M23/20 , C12M23/26 , C12M27/04 , C12M29/06 , C12M37/00
Abstract: A container system includes a bag having of one or more sheets of flexible polymeric material, the bag having an interior surface at least partially bounding a chamber that is adapted to hold a fluid. A sparger is secured to the interior surface of the bag so that a compartment is formed between the interior surface of the bag and the sparger. At least a portion of the sparger includes a sparging sheet formed from a flexible sheet of a gas permeable material. A tubular port or tube is coupled with the bag so that a passage bounded by the tubular port or tube communicates with the compartment.
Abstract translation: 容器系统包括具有一层或多层柔性聚合材料的袋，该袋具有至少部分地限定适于保持流体的室的内表面。 将分布器固定到袋的内表面，使得在袋的内表面和分布器之间形成隔室。 喷射器的至少一部分包括由气体可渗透材料的柔性片形成的喷射片。 管状端口或管与袋连接，使得由管状端口或管道限定的通道与隔室连通。
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公开(公告)号：US11944945B2
公开(公告)日：2024-04-02
申请号：US17105810
申请日：2020-11-27
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Jeremy K. Larsen , Clinton C. Staheli , Brandon M. Knudsen
IPC: B01F27/2121 , B01F27/191 , B01F27/213 , B01F27/88 , B01F27/91 , B01F33/00 , B01F35/32 , B01F35/40 , B01F35/41 , B01F35/513 , B01F27/80 , B01F35/31 , B01F35/50
CPC classification number: B01F27/2121 , B01F27/191 , B01F27/213 , B01F27/88 , B01F27/91 , B01F33/86 , B01F35/322 , B01F35/3231 , B01F35/40 , B01F35/4121 , B01F35/513 , B01F27/80 , B01F35/31 , B01F35/41 , B01F35/4112 , B01F35/514
Abstract: A fluid mixing system includes a flexible bag having a first end, an opposing second end, and an interior surface bounding a compartment; a retainer coupled to the second end of the flexible bag, the retainer having a retention cavity formed thereon that communicates with the compartment of the flexible bag; and an elongated member having a first end rotatably coupled to the first end of the flexible bag and an opposing second end freely disposed within the retention cavity of the retainer so that the second end of the elongated member can rotate within the retention cavity relative to the retainer.
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公开(公告)号：US11821553B2
公开(公告)日：2023-11-21
申请号：US17576671
申请日：2022-01-14
Applicant: Life Technologies Corporation
Inventor： Ryan S. Beus , Brandon R. Burtenshaw , Eric Davis , Patrick L. Draper , Michael E. Goodwin , Brandon M. Knudsen , Jeremy K. Larsen , Kevin R. Pickup
CPC classification number: F16L33/207 , A61M39/12 , B29C65/565 , B29C65/68 , B29C66/1122 , B29C66/12 , B29C66/1222 , B29C66/1224 , B29C66/131 , B29C66/30321 , B29C66/5344 , B29C66/7315 , B29C66/7392 , B29C66/7394 , B29C66/73753 , F16L33/227 , B29C66/71 , B29L2031/24 , B29C66/71 , B29K2023/06 , B29C66/71 , B29K2023/065
Abstract: A method for coupling a tube to a tube fitting includes radially outwardly expanding a tubular compression collar from a constricted state to an expanded state, the compression collar having a throughway extending there through and being made of a resiliently flexible material. An end of the tube is inserted within the throughway of the expanded compression collar, the tube bounding a passage. A tube fitting is inserted within the passage of the tube. The compression collar is allowed to resiliently rebound back towards the constricted state so that the compression collar pushes the tube against the tube fitting.
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