公开(公告)号：US08705257B2

公开(公告)日：2014-04-22

申请号：US13287246

申请日：2011-11-02

申请人： Nobuhisa Yamaguchi ,  Yasuyuki Sakai

发明人： Nobuhisa Yamaguchi ,  Yasuyuki Sakai

IPC分类号： H02H7/122 ,  H02M7/5387 ,  H01L23/52

CPC分类号： H05K7/209 ,  H01L2224/33 ,  H01L2924/0002 ,  H02M7/003 ,  H01L2924/00

摘要： A switching module includes a series-connected unit of a first flowing restriction element and a second flowing restriction element, the first flowing restriction element having an opening and closing function of opening and closing a flowing path of current, and the second flowing restriction element having at least one of a rectifying function of restricting the direction in which current flows and the opening and closing function, and a snubber circuit connected to the series-connected unit in parallel. A first wiring line connecting between the first flowing restriction element and the snubber circuit, a second wiring line connecting between the second flowing restriction element and the snubber circuit, a third wiring line connecting between the first flowing restriction element and the second flowing restriction element, the first flowing restriction element, the second flowing restriction element, and the snubber circuit are formed substantially integrally with each other by using an insulator.

摘要翻译： 开关模块包括第一流动限制元件和第二流动限制元件的串联单元，第一流动限制元件具有打开和关闭电流流动通路的打开和关闭功能，并且第二流动限制元件具有 限制电流流动的方向的整流功能和开关功能中的至少一个以及并联连接到串联单元的缓冲电路中的至少一个。 连接在第一流动限制元件和缓冲电路之间的第一布线，连接在第二流动限制元件和缓冲电路之间的第二布线，连接在第一流动限制元件和第二流动限制元件之间的第三布线， 第一流通限制元件，第二流动限制元件和缓冲电路通过使用绝缘体彼此基本上一体地形成。

公开(公告)号：US20120183989A1

公开(公告)日：2012-07-19

申请号：US13392226

申请日：2010-07-28

申请人： Hitoshi Matsui ,  Yasuyuki Sakai ,  Teruo Fujii ,  Shoji Takeuchi ,  Yukiko Tsuda

发明人： Hitoshi Matsui ,  Yasuyuki Sakai ,  Teruo Fujii ,  Shoji Takeuchi ,  Yukiko Tsuda

IPC分类号： G01N21/64 ,  C12Q1/02 ,  C12M1/34 ,  C12N5/071

CPC分类号： C12M23/20 ,  C12M23/24 ,  C12M25/14 ,  C12M41/46 ,  C12N5/0671 ,  C12N2503/00 ,  C12N2533/30 ,  C12N2533/54 ,  G01N33/5044

摘要： A method for culturing hepatocytes, wherein hepatocytes embedded in an extracellular matrix is placed on a gas-permeable membrane and the hepatocytes are cultured while being supplied with oxygen from the gas-permeable membrane side. By this, the polarity in the hepatocytes can be induced and a bile canaliculus can be formed in a short period of time. Further, the formed polarity can be maintained for a longer period.

摘要翻译： 一种培养肝细胞的方法，其中将包埋在细胞外基质中的肝细胞置于透气膜上，并且在从透气膜侧供给氧的同时培养肝细胞。 由此，可以诱导肝细胞中的极性，并且可以在短时间内形成胆小管。 此外，所形成的极性可以保持更长的时间。

公开(公告)号：US20100164274A1

公开(公告)日：2010-07-01

申请号：US12524550

申请日：2007-01-26

申请人： Yasunori Kondo ,  Hiroyoshi Iwata ,  Yasuyuki Sakai ,  Makoto Oda ,  Tooru Niihara ,  Isao Makiuchi ,  Kunihiro Nagamori ,  Katsumi Inomata ,  Hidekazu Anai

发明人： Yasunori Kondo ,  Hiroyoshi Iwata ,  Yasuyuki Sakai ,  Makoto Oda ,  Tooru Niihara ,  Isao Makiuchi ,  Kunihiro Nagamori ,  Katsumi Inomata ,  Hidekazu Anai

IPC分类号： E21D9/08 ,  E21C27/20 ,  E21D23/03

CPC分类号： E21D9/117 ,  E21D9/0879

摘要： The present invention provides a shield machine (1) including an excavator (5) capable of excavating tunnels of various cross-sectional shapes, the excavator (5) including: a rotary drum (40) supported at a front end side portion of a shield machine main body (2) to be rotatable around a first center axis (A1); a cutter supporting frame (50) supported by the rotary drum to be rotatable around a second center axis (A2); a rotary cutter head (60) supported by the cutter supporting frame (50) to be rotatable around a third center axis (A3) and including a plurality of cutter bits (61) on a surface thereof; a rotary auxiliary cutter head (70) supported by the rotary drum (40) to be rotatable around a fourth center axis (A4); and first, third, and fourth rotating mechanisms (45, 65, and 75), and a swinging drive mechanism (55) configured to respectively cause the rotary drum (40), the rotary cutter head (60), the rotary auxiliary cutter head (70), and the cutter supporting frame (50) to independently rotate.

摘要翻译： 本发明提供一种包括能够挖掘各种截面形状的隧道的挖掘机（5）的盾构机（1），所述挖掘机（5）包括：旋转滚筒（40），其被支撑在屏蔽件的前端侧部分 机器主体（2）能够围绕第一中心轴线（A1）旋转; 由所述旋转滚筒支撑以能够围绕第二中心轴线（A2）旋转的切割器支撑框架（50）; 旋转刀头（60），其由所述切割器支撑框架（50）支撑以能够围绕第三中心轴线（A3）旋转，并且在其表面上包括多个切割刀头（61）; 旋转辅助刀头（70），其由所述旋转鼓（40）支撑以围绕第四中心轴线（A4）旋转; 和第一，第三和第四旋转机构（45,65和75）以及摆动驱动机构（55），其构造成分别使旋转滚筒（40），旋转切割头（60），旋转辅助切割头 （70）和切割器支撑框架（50）独立旋转。

公开(公告)号：US20080145925A1

公开(公告)日：2008-06-19

申请号：US11885889

申请日：2005-12-08

申请人： Yasuyuki Sakai ,  Teruo Fujii ,  Serge Ostrovidov ,  Hiroaki Inui ,  Jinji Mizuno

发明人： Yasuyuki Sakai ,  Teruo Fujii ,  Serge Ostrovidov ,  Hiroaki Inui ,  Jinji Mizuno

IPC分类号： C12M1/12

CPC分类号： C12M35/08 ,  C12M23/34 ,  C12M29/10

摘要： A cell culture chamber includes: a top compartment and a bottom compartment that are separated by a semi-permeable membrane inside a supporting body; a culture solution supply flow path that supplies culture solution to an interior of the bottom compartment; a culture solution discharge flow path that discharges culture solution from the interior of the bottom compartment; a circulation flow path that is used to circulate fluid within the interior of the top compartment; and a cell culturing portion is formed inside the top compartment by a sieve structure that is formed by aperture portions through which a fluid is able to pass but through which cultured cells cannot pass, and by wall portions.

摘要翻译： 细胞培养室包括：顶部隔室和底部隔室，其由支撑体内的半透膜隔开; 将培养液供给到所述底部室的内部的培养液供给流路; 从底部室的内部排出培养液的培养液排出流路; 用于使流体在顶部隔间的内部循环的循环流动路径; 并且细胞培养部分通过筛孔结构形成在顶部隔室内，该筛结构由流体能够通过的通孔，通过培养的细胞不能通过的孔部分和壁部形成。

公开(公告)号：US07015578B2

公开(公告)日：2006-03-21

申请号：US10853247

申请日：2004-05-26

申请人： Shigenobu Nakamura ,  Hiroshi Ishiyama ,  Yasuyuki Sakai

发明人： Shigenobu Nakamura ,  Hiroshi Ishiyama ,  Yasuyuki Sakai

IPC分类号： H01L23/34

CPC分类号： H01L25/112 ,  H01L23/4334 ,  H01L23/473 ,  H01L24/40 ,  H01L24/48 ,  H01L24/73 ,  H01L2224/05599 ,  H01L2224/40137 ,  H01L2224/45099 ,  H01L2224/48091 ,  H01L2224/48247 ,  H01L2224/73221 ,  H01L2224/83801 ,  H01L2224/84801 ,  H01L2224/85399 ,  H01L2924/00014 ,  H01L2924/01004 ,  H01L2924/01006 ,  H01L2924/01013 ,  H01L2924/0103 ,  H01L2924/01033 ,  H01L2924/01047 ,  H01L2924/01059 ,  H01L2924/01074 ,  H01L2924/01079 ,  H01L2924/01082 ,  H01L2924/01087 ,  H01L2924/1305 ,  H01L2924/13055 ,  H01L2924/181 ,  H01L2924/351 ,  H01L2924/00 ,  H01L2924/00012 ,  H01L2224/45015 ,  H01L2924/207 ,  H01L2224/37099

摘要： A semiconductor unit has semiconductor modules and cooling members. The semiconductor module includes power devices with a flat shape, the first electrode bonded to the first device surface, the second electrode bonded to the second device surface, the first terminals connecting to a device control circuit, the second terminals connecting to a device driving circuit, and mold resin unifying the devices, the first electrode, the second electrode, the first terminals, and the second terminals in a unit. The mold resin is so formed that the first electrode face and second electrode face are exposed. The cooling members sandwich the semiconductor modules through insulating members. The semiconductor unit has the first electrode face of the first electrode coplanar with the first resin face of the mold resin, and/or the second electrode face of the second electrode coplanar with the second resin face of the mold resin.

摘要翻译： 半导体单元具有半导体模块和冷却构件。 半导体模块包括具有平坦形状的功率器件，第一电极接合到第一器件表面，第二电极接合到第二器件表面，第一端子连接到器件控制电路，第二端子连接到器件驱动电路 和模制树脂以单元统一装置，第一电极，第二电极，第一端子和第二端子。 模制树脂被形成为使第一电极面和第二电极面露出。 冷却构件通过绝缘构件夹持半导体模块。 半导体单元具有与模具树脂的第一树脂面共面的第一电极的第一电极面和/或第二电极的第二电极面与模制树脂的第二树脂面共面。

公开(公告)号：US06372233B1

公开(公告)日：2002-04-16

申请号：US09555815

申请日：2000-06-05

申请人： Eiichi Miyauchi ,  Yasuyuki Sakai ,  Keiko Sano

发明人： Eiichi Miyauchi ,  Yasuyuki Sakai ,  Keiko Sano

IPC分类号： A61K700

CPC分类号： A61K9/0014 ,  A61K9/08 ,  A61K31/593 ,  A61K47/10 ,  A61K47/26

摘要： The present invention aims to provide a lotion stably maintaining maxacalcitol and having excellent percutaneous absorption. The present invention provides lotions comprising maxacalcitol as an active ingredient and a nonionic surfactant as an additive, as well as lotions which further contains a polyhydric alcohol and a solubilizer as additives besides a nonionic surfactant.

公开(公告)号：US5455042A

公开(公告)日：1995-10-03

申请号：US250453

申请日：1994-05-27

申请人： Yasuyuki Sakai ,  Noriyuki Suzuki ,  Tetsuo Kudo ,  Kuniomi Marumo ,  Toshiyuki Aizawa ,  Kunio Imamura ,  Shuichi Sugita ,  Kazuo Kanbayashi

发明人： Yasuyuki Sakai ,  Noriyuki Suzuki ,  Tetsuo Kudo ,  Kuniomi Marumo ,  Toshiyuki Aizawa ,  Kunio Imamura ,  Shuichi Sugita ,  Kazuo Kanbayashi

IPC分类号： A61K9/06 ,  A61K9/00 ,  A61K9/70 ,  A61K47/32 ,  A61L15/58

CPC分类号： A61K9/7053 ,  A61K47/32 ,  A61K9/0014 ,  A61K9/7023 ,  A61K9/7061

摘要： The subject invention relates to an ointment comprising a homogeneous mixture of polymer or copolymer of N-vinylacetamide, as an essential component, water and/or alcohols, and a pharmacologically active component. The ointment may be coated or plastered onto the skin or mucosa of a human being or animal in order to effect a therapeutic response.

摘要翻译： 本发明涉及一种软膏剂，其包含N-乙烯基乙酰胺作为必要成分的聚合物或共聚物的均匀混合物，水和/或醇，以及药理活性成分。 软膏可以涂覆或涂抹在人或动物的皮肤或粘膜上以实现治疗反应。

公开(公告)号：US5254338A

公开(公告)日：1993-10-19

申请号：US652715

申请日：1991-02-08

申请人： Yasuyuki Sakai ,  Noriyuki Suzuki ,  Tetsuo Kudo ,  Kuniomi Marumo ,  Toshiyuki Aizawa ,  Kunio Imamura ,  Shuichi Sugita ,  Kazuo Kanbayashi

发明人： Yasuyuki Sakai ,  Noriyuki Suzuki ,  Tetsuo Kudo ,  Kuniomi Marumo ,  Toshiyuki Aizawa ,  Kunio Imamura ,  Shuichi Sugita ,  Kazuo Kanbayashi

IPC分类号： A61K9/06 ,  A61K9/00 ,  A61K9/70 ,  A61K47/32 ,  A61L15/58

CPC分类号： A61K9/7053 ,  A61K47/32 ,  A61K9/0014 ,  A61K9/7023 ,  A61K9/7061

摘要： A (co)polymer suitable for bases or auxiliary agents for external application (for example, hydrophilic gels, adhesives, thickeners or excipients) to be coated or plastered onto the skin or mucosa of a human being or animal, such as ointment agents (ointment, hydrogel, jelly or cream), plastering agents (molded poultice, tape agent or plaster agent), sticky bandages (sticky bandage, strap, wound strap, surgical tape, taping material, supporter), and to preparations for external application containing same.

公开(公告)号：US4938964A

公开(公告)日：1990-07-03

申请号：US281356

申请日：1988-12-08

申请人： Yasuyuki Sakai ,  Toyoaki Ishikura ,  Kazuo Kanbayashi ,  Tadashi Kato ,  Koichi Abe

发明人： Yasuyuki Sakai ,  Toyoaki Ishikura ,  Kazuo Kanbayashi ,  Tadashi Kato ,  Koichi Abe

IPC分类号： A61K9/00 ,  A61K9/70 ,  A61K31/19 ,  A61K47/32

CPC分类号： A61K9/7053 ,  A61K31/19 ,  A61K47/32 ,  A61K9/0014 ,  A61K9/7061

摘要： An external dermatological composition containing a drug supply layer carried on a support and containing 5% to 35% by weight of ketoprofen in an acrylic or methacrylic copolymer, which copolymer is composed of (i) 0.5% to 11.0% by weight of an .alpha.,.beta.-unsaturated carboxylic acid or its anhydride, (ii) 0.1% to 28.0% by weight of a vinyl monomer, (iii) 1.0% to 5.5% by weight of a hydroxy C.sub.2 -C.sub.4 alkyl ester of acrylic or methacrylic acid, and (iv) a balance of a C.sub.4 -C.sub.18 alkyl ester of acrylic or methacrylic acid, and has a glass transition point of -15.degree. C. to -70.degree.C.

公开(公告)号：US20130218937A1

公开(公告)日：2013-08-22

申请号：US13879715

申请日：2010-12-27

申请人： Yusuke Naito ,  Yasuyuki Sakai

发明人： Yusuke Naito ,  Yasuyuki Sakai

IPC分类号： G06F5/01

CPC分类号： G06F5/01 ,  G06F7/725 ,  G06F2207/7261 ,  H04L9/3066 ,  H04L9/3252 ,  H04L2209/12

摘要： A scalar multiplication unit references a t-bit sequence representing a random number k one bit at a time from the most significant bit, and upon each referencing, sets in a work variable R[0] a value obtained by doubling a specific point G on an elliptic curve set in a scalar multiplication variable R, and sets in a work variable R[1] a value obtained by adding the specific point G to the work variable R[0]. The scalar multiplication unit 122 sets the work variable R[0] in the scalar multiplication variable R if the value of the referenced bit is 0, and sets the work variable R[1] in the scalar multiplication variable R if the value of the referenced bit is 1. A scalar multiple point output unit 123 outputs as a scalar multiple point kG a value obtained by subtracting a constant value 2tG from the scalar multiplication variable R.

摘要翻译： 标量乘法单元参考表示随机数k的t位序列，从最高有效位一次一位，并且在每次引用时，将工作变量R [0]设置为通过将特定点G加倍获得的值 在标量乘法变量R中设置的椭圆曲线，并且将工作变量R [1]设定为通过将特定点G加到工作变量R [0]而获得的值。 如果参考位的值为0，则标量乘法单元122将标量乘法变量R中的工作变量R [0]设置为标准乘法变量R中的工作变量R [1]，如果所引用的值 位是1.标量多点输出单元123作为标量多点kG输出通过从标量乘法变量R中减去常数值2tG而获得的值。