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    SENSOR FOR LIFETIME PLUS SPECTRAL CHARACTERIZATION
    22.
    发明公开
    SENSOR FOR LIFETIME PLUS SPECTRAL CHARACTERIZATION 审中-公开

    公开(公告)号：US20240353326A1

    公开(公告)日：2024-10-24

    申请号：US18539068

    申请日：2023-12-13

    Applicant: Quantum-Si Incorporated

    Inventor： Gerard Schmid ,  Dajiang Yang ,  Eric A.G. Webster ,  Xin Wang ,  Todd Rearick ,  Changhoon Choi ,  Ali Kabiri ,  Kyle Preston

    IPC: G01N21/64

    CPC classification number: G01N21/6428 ,  G01N2021/6417 ,  G01N2021/6439

    Abstract: Some aspects relate to integrated devices for obtaining timing and/or spectral information from incident light. In some embodiments, a pixel may include one or more charge storage regions configured to receive charge carriers generated responsive to incident photons from a light source, with charge carriers stored in the charge storage region(s) indicative of spectral and timing information. In some embodiments, a pixel may include regions having different depths, each configured to generate charge carriers responsive to incident photons. In some embodiments, a pixel may include multiple charge storage regions having different depths, and one or more of the charge storage regions may be configured to receive the incident photons and generate charge carriers therein. In some embodiments, a pixel may include an optical sorting element configured to direct at least some incident photons to one charge storage region and other incident photons to another charge storage region.

    Integrated sensor for lifetime characterization
    23.
    发明授权
    Integrated sensor for lifetime characterization 有权

    公开(公告)号：US11869917B2

    公开(公告)日：2024-01-09

    申请号：US17149574

    申请日：2021-01-14

    Applicant: Quantum-Si Incorporated

    Inventor： Eric A. G. Webster ,  Changhoon Choi ,  Dajiang Yang ,  Xin Wang ,  Todd Rearick ,  Kyle Preston ,  Ali Kabiri ,  Gerard Schmid

    IPC: H01L27/146

    CPC classification number: H01L27/14643 ,  H01L27/14683

    Abstract: Aspects of the technology described herein relate to improved semiconductor-based image sensor designs. In some embodiments, an integrated circuit may comprise a photodetection region and a drain region electrically coupled to the photodetection region, and the photodetection region may be configured to induce an intrinsic electric field in a direction from the photodetection region to the drain region(s). In some embodiments, a charge storage region and the drain region may be positioned on a same side of the photodetection region. In some embodiments, at least one drain layer may be configured to receive incident photons and/or charge carriers via the photodetection region. In some embodiments, an integrated circuit may comprise a plurality of pixels and a control circuit configured to control a transfer of charge carriers in the plurality of pixels.

    OPTICAL MICRODISKS FOR INTEGRATED DEVICES
    26.
    发明申请
    OPTICAL MICRODISKS FOR INTEGRATED DEVICES 有权

    公开(公告)号：US20220397720A1

    公开(公告)日：2022-12-15

    申请号：US17893101

    申请日：2022-08-22

    Applicant: Quantum-Si Incorporated

    Inventor： Ali Kabiri ,  Bing Shen ,  Gerard Schmid ,  James Beach ,  Kyle Preston ,  Sharath Hosali

    IPC: G02B6/122 ,  G02B6/136

    Abstract: Apparatus and methods for improving optical signal collection in an integrated device are described. A microdisk can be formed in an integrated device and increase collection and/or concentration of radiation incident on the microdisk and re-radiated by the microdisk. An example integrated device that can include a microdisk may be used for analyte detection and/or analysis. Such an integrated device may include a plurality of pixels, each having a reaction chamber for receiving a sample to be analyzed, an optical microdisk, and an optical sensor configured to detect optical emission from the reaction chamber. The microdisk can comprise a dielectric material having a first index of refraction that is embedded in one or more surrounding materials having one or more different refractive index values.

    SINGLE MOLECULE DETECTION SYSTEM USING PHOTOBLEACHING INFORMATION
    28.
    发明申请
    SINGLE MOLECULE DETECTION SYSTEM USING PHOTOBLEACHING INFORMATION 有权

    公开(公告)号：US20220128469A1

    公开(公告)日：2022-04-28

    申请号：US17511249

    申请日：2021-10-26

    Applicant: Quantum-Si Incorporated

    Inventor： Brian Reed ,  Kyle Preston ,  Xinghua Shi ,  Gerard Schmid

    IPC: G01N21/64 ,  G01N33/68

    Abstract: Aspects of the present disclosure relate to techniques for calibrating a system comprising integrated device. According to some embodiments, there is provided a method for calibrating a system comprising an integrated device, the method comprising: exciting, with light from at least one excitation source, a reference dye molecule disposed in a chamber of the integrated device; obtaining a signal emitted by the reference dye molecule, the signal containing information representative of a bleaching time of the reference dye molecule; and adjusting one or more characteristics of the system based on the bleaching time of the reference dye molecule.

    SYSTEMS AND METHODS FOR SAMPLE PROCESS SCALING
    29.
    发明申请
    SYSTEMS AND METHODS FOR SAMPLE PROCESS SCALING 有权

    公开(公告)号：US20220128456A1

    公开(公告)日：2022-04-28

    申请号：US17508783

    申请日：2021-10-22

    Applicant: Quantum-Si Incorporated

    Inventor： Todd Rearick ,  Ali Kabiri ,  Gerard Schmid ,  Kyle Preston

    IPC: G01N21/03 ,  G01N33/68

    Abstract: Aspects of the present disclosure relate to methods and systems for increasing the number of samples that can be processed in parallel by an integrated device An integrated device is provided having at least two reaction chambers disposed above an active photodetection area of a single pixel, such that the pixel is sensitive to photons from each of the at least two reaction chambers. In some embodiments, an integrated device may have at least four or more reaction chambers per photodetector. Signals from multiple reaction chambers may be distinguished using any combination of multiplexing techniques including techniques for waveguide multiplexing, intensity multiplexing, and/or lifetime multiplexing. According to further aspects of the technology described herein, there is provided techniques for increasing the amount of sample that can be processed by a single device by reloading an integrated device repeated times to process an increased number of samples by a single device.

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