Fatty acid esters as anti-Malassezia agents

    公开(公告)号:US12274775B2

    公开(公告)日:2025-04-15

    申请号:US17428309

    申请日:2019-02-04

    Applicant: SYMRISE AG

    Abstract: The present invention primarily relates to a fatty acid ester or mixture of two or more fatty acid esters or mixture comprising one or more fatty acid esters, wherein the fatty acid ester or one, two, three or more, preferably all, of the fatty acid ester(s) is/are selected from the group consisting of 3-hydroxypropyl caprylate, glyceryl monocaprylate, 3-hydroxypropyl undecylenate and glyceryl monoundecylenate, for use in the treatment of an excess of Malassezia on the skin surface of mammals, preferably of humans. The present invention further relates to particular mixtures or products, and to the cosmetic, non-therapeutic use of fatty acid esters or of mixtures or products comprising fatty acid esters as defined herein to reduce the amount of Malassezia on the skin surface of mammals, preferably of humans.

    PREPARATIONS WITH IMPROVED PHYSICAL PROPERTIES
    27.
    发明申请
    PREPARATIONS WITH IMPROVED PHYSICAL PROPERTIES 有权
    具有改进的物理性质的制备

    公开(公告)号:US20150250693A1

    公开(公告)日:2015-09-10

    申请号:US14638367

    申请日:2015-03-04

    Applicant: SYMRISE AG

    Abstract: A preparation is described comprising one or more alcohols of the formula (I), wherein in each case one of the two moieties Ra or Rb represents hydrogen and the other moiety Ra or Rb in each case represents a straight-chain or branched acyl moiety having 2 to 10 carbon atoms, and one or more further compounds, wherein the preparation is an O/W emulsion, the particle size distribution for which the following applies: D(v, 0.9)=40 μm or less, wherein in the preparation the total quantity of the alcohol(s) of the formula (I) is selected in such a way that the O/W emulsion, compared to a comparison emulsion which having an otherwise identical composition does not comprise any alcohol of the formula (I), has an increased emulsion stability, and/or wherein the preparation is a surfactant-containing preparation and the total quantity of the alcohol(s) of the formula (I) in the preparation is selected in such a way that the preparation, compared to a comparison preparation which having an otherwise identical composition does nor comprise any alcohol of the formula (I), has an increased viscosity at 22.7° C.

    Abstract translation: 描述了包含一种或多种式(I)的醇的制剂,其中在每种情况下,两个部分Ra或Rb中的一个表示氢,而另一个部分Ra或Rb在每种情况下表示具有直链或支链酰基部分, 2至10个碳原子,和一种或多种其它化合物,其中制剂是O / W乳液,其适用的粒径分布:D(v,0.9)=40μm或更小,其中在制备中 选择式(I)的醇的总量,使得O / W乳液与具有相同组成的比较乳液相比不包含任何式(I)的任何醇, 具有增加的乳液稳定性,和/或其中制剂是含表面活性剂的制剂,并且选择制剂中式(I)的醇的总量,使得制剂与 比较准备 相同的组成不含或不包含式(I)的任何醇,在22.7℃具有增加的粘度

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