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公开(公告)号：US20210402396A1
公开(公告)日：2021-12-30
申请号：US17343409
申请日：2021-06-09
Applicant: SAMSUNG ELECTRONICS CO., LTD.
Inventor： Moon Seong Park , Kak Namkoong , Won Jong Jung
Abstract: Provided are a microfluidic chip, and an apparatus and a method for detecting biomolecules by using the microfluidic chip. According to an example embodiment, the microfluidic chip includes: a first storage configured to accommodate a sample, the sample including target materials; a plurality of second storages connected to the first storage, the plurality of second storages including reactants for the target materials; and a plurality of well arrays connected to the plurality of second storages, respectively, and configured to accommodate a solution of the sample, in which the reactants for the target materials are dissolved.
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公开(公告)号：US10420483B2
公开(公告)日：2019-09-24
申请号：US15363293
申请日：2016-11-29
Applicant: SAMSUNG ELECTRONICS CO., LTD.
Inventor： Yeol Ho Lee , Kak Namkoong , Myoung Hoon Jung , Young Jun Koh
IPC: A61B5/053 , A61B5/00 , A61B5/0402 , A61B5/0408
Abstract: An apparatus and method for measuring a bioelectric impedance is provided. The apparatus may measure the bioelectric impedance using three electrodes. The apparatus may measure the bioelectric impedance by compensating for a change of a contact impedance.
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公开(公告)号：US09657341B2
公开(公告)日：2017-05-23
申请号：US14074590
申请日：2013-11-07
Applicant: Samsung Electronics Co., Ltd.
Inventor： Chin-sung Park , Kak Namkoong , Joon-sub Shim , Won-seok Chung , Kyung-ho Kim , Joon-ho Kim , Won-jong Jung
CPC classification number: C12Q1/686 , B01L3/5027 , B01L3/527 , B01L7/525 , B01L2200/025 , B01L2200/028 , B01L2200/0684 , B01L2200/10 , B01L2300/0672 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2400/0487 , B01L2400/0655 , B01L2400/0683 , B01L2400/086
Abstract: A microfluidic system for analyzing nucleic acid, the microfluidic system including a reagent supply device including a sample chamber into which a sample can be injected, one or more reagent chambers for containing one or more reagents for extracting nucleic acid from the sample, and a waste chamber in which the used reagent can be discarded; a binding-lysis chamber in which cells are captured from the sample and lysed to form a cell lysate containing nucleic acid; plurality of particles for cell binding disposed in the binding-lysis chamber; a plurality of rehydration chambers into which the cell lysate formed in the binding-lysis chamber can be distributed and mixed with a nucleic acid amplification reagent to form an amplification reaction mixture; a plurality of amplification chambers in which a nucleic acid amplification reaction is performed on the amplification reaction mixture introduced from the plurality of rehydration chambers; and a flow channel system including an outlet and a plurality of inlets connected to the reagent supply device and forming an integrated fluid flow between the binding-lysis chamber, the rehydration chambers, and the amplification chambers.
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24.发明授权Method and apparatus for analyzing nucleic acid by compensating for crosstalk in polymerase chain reaction data and other data 有权通过补偿聚合酶链反应数据和其他数据中的串扰来分析核酸的方法和装置公开(公告)号：US09139872B2
公开(公告)日：2015-09-22
申请号：US13754628
申请日：2013-01-30
Applicant: Samsung Electronics Co., Ltd.
Inventor： Kyung-ho Kim , Soo-kwan Lee , Joon-ho Kim , Kak Namkoong , Sun-ok Jung , Won-seok Chung
IPC: C12Q1/68
CPC classification number: C12Q1/686 , C12Q1/68 , C12Q1/6848 , C12Q2537/165 , C12Q2563/107
Abstract: A method of analyzing nucleic acid by compensating for crosstalk in polymerase chain reaction (PCR) data and other data, wherein crosstalk signals associated with multiple fluorescent dyes are corrected by using fluorescent intensity variations detected from a concentration difference of the fluorescent dyes, and apparatus for performing the method.
Abstract translation: 通过补偿聚合酶链反应（PCR）数据和其他数据中的串扰来分析核酸的方法，其中通过使用从荧光染料的浓度差检测的荧光强度变化来校正与多种荧光染料相关联的串扰信号，以及用于 执行该方法。
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25.发明授权Apparatus and method of detecting and controlling fluid in microfluidic device 有权在微流体装置中检测和控制流体的装置和方法公开(公告)号：US09095851B2
公开(公告)日：2015-08-04
申请号：US13722057
申请日：2012-12-20
Applicant: Samsung Electronics Co., Ltd.
Inventor： Won-seok Chung , Kak Namkoong , Chin-sung Park , Kyung-ho Kim , Joon-ho Kim
CPC classification number: B01L3/502746 , G01N35/00069 , G01N35/1095 , Y10T137/0391
Abstract: A fluid control apparatus including a detecting unit including a light source for irradiating light toward a microfluidic device, and a photodetector for detecting light reflected from the microfluidic device, a transporting unit for moving the detecting unit; and a determining unit for controlling a transporting operation by the transporting unit, where determining a state of a fluid at a particular position relative to the microfluidic device is based on light reflected from the microfluidic device, and method of using same.
Abstract translation: 一种流体控制装置，包括：检测单元，包括用于向微流体装置照射光的光源;以及光检测器，用于检测从微流体装置反射的光;传送单元，用于移动检测单元; 以及用于控制由所述输送单元进行的输送操作的确定单元，其中基于从所述微流体装置反射的光来确定相对于所述微流体装置的特定位置处的流体的状态及其使用方法。
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Patent Agency Ranking
公开(公告)号：US20140356853A1
公开(公告)日：2014-12-04
申请号：US14167583
申请日：2014-01-29
Applicant: Samsung Electronics Co., Ltd.
Inventor： Won-seok CHUNG , Kak Namkoong , Kyung-ho Kim , Chin-sung Park , Joon-ho Kim , Joon-sub Shim , Won-jong Jung
IPC: C12Q3/00
CPC classification number: C12Q3/00 , C12Q1/686 , C12Q2565/629
Abstract: A nucleic acid analysis system comprising a seating area configured to receive a microfluidic cartridge; a pneumatic module configured to supply a pneumatic pressure or a vacuum to the cartridge when mounted on the seating area; a thermal module configured to control temperature in a predetermined portion of the cartridge when mounted on the seating area; an optic module positioned to irradiate light onto the cartridge when mounted on the seating area, and detect light generated or reflected from a sample inside the cartridge when mounted on the seating area; a fluid sensing module that determines whether a fluid in a predetermined portion of a cartridge mounted on the seating area is in a gaseous state or a liquid state; a scanning module that moves the optic module and the fluid sensing module relative to the seating area; and a control module that controls operations of the pneumatic module, the thermal module, the optic module, the fluid sensing module, and the scanning module, and processes and analyzes data received therefrom.
Abstract translation: 一种核酸分析系统，包括配置成接收微流控盒的座位区域; 气动模块，其构造成当安装在所述座位区域时向所述盒提供气动压力或真空; 配置为当安装在座位区上时控制盒的预定部分中的温度的热模块; 定位成当安装在就座区上时将光照射到盒上的光学模块，以及当安装在座位区域上时，检测从盒内的样品产生或反射的光; 流体感测模块，其确定安装在所述就座区域上的盒的预定部分中的流体是处于气态还是液态; 扫描模块，其相对于所述座位区域移动所述光学模块和所述流体感测模块; 以及控制模块，其控制气动模块，热模块，光模块，流体感测模块和扫描模块的操作，并处理和分析从其接收的数据。
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公开(公告)号：US20140206073A1
公开(公告)日：2014-07-24
申请号：US14074590
申请日：2013-11-07
Applicant: Samsung Electronics Co., Ltd.
Inventor： Chin-sung Park , Kak Namkoong , Joon-sub Shim , Won-seok Chung , Kyung-ho Kim , Joon-ho Kim , Won-jong Jung
IPC: C12Q1/68
CPC classification number: C12Q1/686 , B01L3/5027 , B01L3/527 , B01L7/525 , B01L2200/025 , B01L2200/028 , B01L2200/0684 , B01L2200/10 , B01L2300/0672 , B01L2300/0816 , B01L2300/0864 , B01L2300/0867 , B01L2400/0487 , B01L2400/0655 , B01L2400/0683 , B01L2400/086
Abstract: A microfluidic system for analyzing nucleic acid, the microfluidic system including a reagent supply device including a sample chamber into which a sample can be injected, one or more reagent chambers for containing one or more reagents for extracting nucleic acid from the sample, and a waste chamber in which the used reagent can be discarded; a binding-lysis chamber in which cells are captured from the sample and lysed to form a cell lysate containing nucleic acid; plurality of particles for cell binding disposed in the binding-lysis chamber; a plurality of rehydration chambers into which the cell lysate formed in the binding-lysis chamber can be distributed and mixed with a nucleic acid amplification reagent to form an amplification reaction mixture; a plurality of amplification chambers in which a nucleic acid amplification reaction is performed on the amplification reaction mixture introduced from the plurality of rehydration chambers; and a flow channel system including an outlet and a plurality of inlets connected to the reagent supply device and forming an integrated fluid flow between the binding-lysis chamber, the rehydration chambers, and the amplification chambers.
Abstract translation: 一种用于分析核酸的微流体系统，所述微流体系统包括试剂供应装置，其包括可以注入样品的样品室，用于容纳用于从样品中提取核酸的一种或多种试剂的一个或多个试剂室和废物 可以丢弃使用的试剂的室; 结合裂解室，其中细胞从样品中捕获并裂解以形成含有核酸的细胞裂解物; 用于细胞结合的多个颗粒设置在结合裂解室中; 多个再结合室，其中在结合 - 溶解室中形成的细胞裂解物可以与核酸扩增试剂分配并混合以形成扩增反应混合物; 多个扩增室，其中对从多个再水化室引入的扩增反应混合物进行核酸扩增反应; 以及流道系统，其包括连接到试剂供应装置的出口和多个入口，并且在结合 - 溶解室，再水化室和扩增室之间形成一体的流体流。
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公开(公告)号：US12005447B2
公开(公告)日：2024-06-11
申请号：US17889085
申请日：2022-08-16
Applicant: SAMSUNG ELECTRONICS CO., LTD.
Inventor： Won Jong Jung , Hyeong Seok Jang , Kak Namkoong , Hyung Jun Youn , Jae Hong Lee
IPC: B01L7/00 , B01L3/00 , G01N15/06 , G01N15/01 , G01N15/075
CPC classification number: B01L3/502715 , B01L7/52 , G01N15/06 , B01L2300/0645 , B01L2300/0654 , B01L2300/0681 , B01L2300/1822 , B01L2300/1894 , G01N15/01 , G01N15/075
Abstract: An apparatus and method for bio-particle detection are provided. The apparatus for bio-particle detection includes: a bio-particle detection chip including a substrate having a plurality of through-hole groups, each through-hole group of the plurality of through-hole groups including through-holes which pass through the substrate from a first surface of the substrate toward an second surface of the substrate opposite to the first surface, and which are configured to accommodate a sample solution loaded therein; and a processor configured to determine a number of through-holes, among the through holes of at least one through-hole group of the plurality of through-hole groups, having a target material encapsulated therein, based on at least one of an electrical signal and an optical signal corresponding to the through-holes of the at least one through-hole group, and to estimate a concentration of the target material based on the determined number.
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公开(公告)号：US11673122B2
公开(公告)日：2023-06-13
申请号：US17321689
申请日：2021-05-17
Inventor： Won Jong Jung , Il Doo Kim , Kak Namkoong , Dong Ha Kim , Yeol Ho Lee , Joon Hyung Lee , Ki Young Chang , Ji Soo Jang , Ha Min Shin , Yoon Hwa Kim
IPC: B01J23/42 , G01N33/497 , B01J23/30 , B01J35/00 , B01J35/06 , G01N27/12 , B01J35/10 , B01J37/00 , B01J37/04 , B01J37/34
CPC classification number: B01J23/42 , B01J23/30 , B01J35/006 , B01J35/0013 , B01J35/06 , B01J35/1066 , B01J35/1071 , B01J35/1076 , B01J37/0018 , B01J37/04 , B01J37/342 , G01N27/127 , G01N33/497
Abstract: A member for a metal oxide nanofiber based gas sensor can include a metal nanoparticle catalyst and can be formed to be functionalized by binding the metal nanoparticle catalyst and an alkali or alkaline earth metal through electrospinning and heat treatment processes. The member can detect a trace amount of a gas with high selectivity and ultra-high sensitivity by uniformly binding the alkali or alkaline earth metal and the metal nanoparticle catalyst through electrospinning and high-temperature heat treatment.
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公开(公告)号：US20230145041A1
公开(公告)日：2023-05-11
申请号：US17684884
申请日：2022-03-02
Inventor： Won Jong JUNG , Ho-Young Kim , Hyeong Seok Jang , Kak Namkoong , Tae Jeong Kim , Jae Hong Lee , Sohyun Jung
IPC: B01L3/00 , C12Q1/6876 , C12Q1/6844 , G01N21/47
CPC classification number: B01L3/502715 , C12Q1/6876 , C12Q1/6844 , G01N21/47 , B01L2300/0654 , B01L2300/0819 , B01L2300/161 , B01L2400/0406
Abstract: The present disclosure relates to an apparatus and method for gene amplification. The apparatus for gene amplification may include: an upper main body comprising a first inlet to receive a sealing solution, a second inlet to receive a sample solution, and an upper passage that allows the sample solution and the sealing solution to move by capillary action; a lower main body disposed to oppose the upper main body, and having a lower passage through which the sealing solution moves by capillary action after being injected from the first inlet of the upper main body; a gene amplification chip configured to be inserted between the upper main body and the lower main body; and a porous medium configured to be inserted between the upper main body and the lower main body.
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