公开(公告)号：US20090292201A1

公开(公告)日：2009-11-26

申请号：US12301238

申请日：2007-05-11

申请人： Jochen Kruecker

发明人： Jochen Kruecker

IPC分类号： A61B5/05

CPC分类号： A61B34/20 ,  A61B90/36 ,  A61B2034/107 ,  A61B2034/2051 ,  A61B2090/364 ,  A61B2090/376 ,  G06T7/30 ,  G06T2207/10072 ,  G06T2207/30021

摘要： A system includes a component that updates a registration between an image space coordinate system and an interventional space coordinate system based on interventional device position information within a patient obtained from intermediate image data indicative of the interventional device location and a position sensor (160) that is located on an interventional device (156) within the patient.

摘要翻译： 一种系统包括：基于从指示介入装置位置的中间图像数据获得的患者内的介入装置位置信息来更新图像空间坐标系和介入空间坐标系之间的配准的组件，以及位于第 位于患者体内的介入装置（156）上。

公开(公告)号：US20070167806A1

公开(公告)日：2007-07-19

申请号：US11563713

申请日：2006-11-28

申请人： Bradford Wood ,  King Li ,  Jeffrey Yanof ,  Jochen Kruecker ,  Christopher Bauer

发明人： Bradford Wood ,  King Li ,  Jeffrey Yanof ,  Jochen Kruecker ,  Christopher Bauer

IPC分类号： A61B8/14

CPC分类号： A61B6/032 ,  A61B6/4417 ,  A61B6/5247 ,  A61B8/13 ,  A61B8/4218 ,  A61B8/4281 ,  A61B8/4416

摘要： A probe includes an ultrasound imaging transducer and a high intensity focused ultrasound (HIFU) transducer. The probe is operatively connected to a localizer which provides information indicative of the position and orientation of the probe in relation to a CT scanner. Information from the ultrasound imaging transducer and the CT scanner is used to assist in planning and performing a HIFU treatment.

摘要翻译： 探针包括超声成像换能器和高强度聚焦超声（HIFU）换能器。 探针可操作地连接到定位器，该定位器提供指示探针相对于CT扫描仪的位置和取向的信息。 来自超声成像传感器和CT扫描仪的信息用于协助规划和执行HIFU治疗。

公开(公告)号：US10850126B2

公开(公告)日：2020-12-01

申请号：US13703750

申请日：2011-05-27

申请人： Dirk Binnekamp ,  Luis Felipe Gutierrez ,  Neil David Glossop ,  Jochen Kruecker ,  Shriram Sethuraman

发明人： Dirk Binnekamp ,  Luis Felipe Gutierrez ,  Neil David Glossop ,  Jochen Kruecker ,  Shriram Sethuraman

IPC分类号： A61N5/10 ,  A61B5/06 ,  A61B6/02 ,  A61B8/12 ,  A61B34/20

摘要： A system and methods for adaptive placement of a treatment element include a placement device (134), and a localization system (120) configured to track progress of the placement device such that a position of a treatment element (146, 132) placed by or to be placed by the placement device is stored in memory. A computer system (142) includes a program (104) implemented in computer readable storage media and configured to compute an effect of the treatment element at the position and determine whether a dosage amount has been achieved by the treatment element for treatment of an organ.

公开(公告)号：US09733336B2

公开(公告)日：2017-08-15

申请号：US12293628

申请日：2007-03-22

申请人： Eric Shen ,  Jochen Kruecker

发明人： Eric Shen ,  Jochen Kruecker

IPC分类号： G01S5/02 ,  A61B5/06 ,  A61B90/00 ,  A61B34/20

CPC分类号： G01S5/021 ,  A61B5/062 ,  A61B34/20 ,  A61B90/36 ,  A61B2034/2051 ,  A61B2034/2055 ,  A61B2090/0818 ,  A61B2090/3975

摘要： A system for local metal distortion correction for using an accurate electromagnetic tracking system in a medical environment comprises an electromagnetic field generator monitoring a medical device having a suitable sensor coil. A correction function, derived from an error correction tool, is applied to the position and orientation readings of the sensor coil. The error correction tool comprises a number of electromagnetic sensors arranged in a fixed and known geometric configuration and is placed surrounding the site of the medical procedure. Sensor data is displayed on an imaging system. In addition, a distortion mapping can be done utilizing optical sensors for relative positioning readings along with an electromagnetic tracking system sensor.

公开(公告)号：US09651662B2

公开(公告)日：2017-05-16

申请号：US12742255

申请日：2008-11-13

申请人： Jochen Kruecker ,  Sheng Xu ,  Hui Jiang

发明人： Jochen Kruecker ,  Sheng Xu ,  Hui Jiang

IPC分类号： G01S15/89 ,  A61B8/08 ,  G01S7/52 ,  A61B8/00

CPC分类号： G01S15/899 ,  A61B8/0833 ,  A61B8/4245 ,  A61B8/4263 ,  G01S7/52074 ,  G01S7/52098 ,  G01S15/8993

摘要： A method for interventional navigation using 3D contrast-enhanced ultrasound (CEUS) imaging includes acquiring a reference 3D CEUS volume and tracking information during a useful lifetime of a contrast enhancement agent administered to the anatomy. Real-time tracked tissue images are acquired during the interventional procedure. In addition, a corresponding CEUS multiplanar reconstruction (MPR) for at least one of the acquired real-time tracked tissue images is generated. At least one of the acquired real-time tracked tissue images is displayed along with the corresponding CEUS MPR. The displayed real-time tracked tissue image includes at least an image of the instrument within the desired portion of the anatomy and the CEUS MPR corresponds to the displayed real-time tracked tissue image. Thus, the contrast enhanced image information and tissue image information are concurrently display for the interventional navigation at least subsequent to the expiration of the contrast enhancement useful lifetime.

公开(公告)号：US20130289393A1

公开(公告)日：2013-10-31

申请号：US13978552

申请日：2012-01-12

申请人： Jochen Kruecker ,  Pingkun Yan ,  Alper Ayvaci

发明人： Jochen Kruecker ,  Pingkun Yan ,  Alper Ayvaci

IPC分类号： A61B8/08

CPC分类号： A61B8/0841 ,  A61B8/4245 ,  A61B8/4254 ,  A61B10/0241 ,  A61B10/0275 ,  A61B34/20 ,  A61B2034/2051 ,  A61B2090/365 ,  A61B2090/378

摘要： A system and method for medical device detection includes a guidance system (38) configured to deliver a surgical device (32) into a subject. A surgical device deployment detector (25, 40, 42, 44) is configured to cooperate with the guidance system and is configured to detect a deployment of the surgical device in the subject. A coordination module (22)is configured to receive input from the guidance system and the deployment detector to determine and record one or more of a location and time of each deployment.

摘要翻译： 用于医疗装置检测的系统和方法包括构造成将外科装置（32）输送到受试者中的引导系统（38）。 手术装置展开检测器（25,40,42,44）构造成与引导系统配合，并被配置成检测被检体内的外科手术装置的部署。 配置模块（22）被配置为接收来自引导系统和部署检测器的输入，以确定和记录每个部署的位置和时间中的一个或多个。

公开(公告)号：US20130039555A1

公开(公告)日：2013-02-14

申请号：US12679026

申请日：2008-10-20

申请人： Sheng Xu ,  Jochen Kruecker ,  Luis Felipe Gutierrez

发明人： Sheng Xu ,  Jochen Kruecker ,  Luis Felipe Gutierrez

IPC分类号： G06K9/32 ,  A61B8/13

CPC分类号： G06T7/0038 ,  G06T7/38 ,  G06T2207/10081 ,  G06T2207/10092 ,  G06T2207/10132 ,  G06T2207/10136 ,  G06T2207/30084

摘要： A 3D ultrasound image from a memory (20) is compared with a 3D diagnostic image from a memory (12) by a localizer and registration unit (30) which determines a baseline transform (Tbase) which registers the 3D diagnostic and ultrasound volume images. The target region continues to be examined by an ultrasound scanner (22) which generates a series of real-time 2D or 3D ultrasound or other lower resolution images. The localizer and registration unit (30) compares one or a group of the 2D ultrasound images with the 3D ultrasound image to determine a motion correction transform (Tmotion). An image adjustment processor or program (32) operates on the 3D diagnostic volume image with the baseline transform (Tbase) and the motion correction transform (Tmotion), to generate a motion corrected image that is displayed on an appropriate display (74).

摘要翻译： 来自存储器（20）的3D超声波图像与来自存储器（12）的3D诊断图像由定位器和注册单元（30）进行比较，定位器和注册单元（30）确定注册3D诊断和超声体积图像的基线变换（Tbase）。 目标区域继续由产生一系列实时2D或3D超声波或其他较低分辨率图像的超声波扫描器（22）进行检查。 定位器和注册单元（30）将一个或一组2D超声波图像与3D超声图像进行比较，以确定运动校正变换（Tmotion）。 图像调整处理器或程序（32）利用基线变换（Tbase）和运动校正变换（Tmotion）对3D诊断体积图像进行操作，以生成显示在适当显示器上的运动校正图像（74）。

公开(公告)号：US20100256495A1

公开(公告)日：2010-10-07

申请号：US12740004

申请日：2008-11-05

申请人： Jochen Kruecker ,  Sheng Xu

发明人： Jochen Kruecker ,  Sheng Xu

IPC分类号： A61B8/14

CPC分类号： A61B8/4254 ,  A61B8/4245 ,  A61B8/481 ,  G06T7/38 ,  G06T2207/10132 ,  G06T2207/30004

摘要： A method (50) for quantitative 3D contrast enhanced ultrasound (CEUS) analysis includes acquiring (54) an initial pair of ultrasound contrast and tissue images of an anatomy. A region of interest (ROI) or volume of interest (VOI) is established (56) in the initial acquired tissue image, which becomes the baseline tissue image. The established ROI/VOI is automatically registered (58) from the initial tissue image to the initial contrast image, which becomes a baseline contrast image. Quantitative analysis is performed (60) on the ROI/VOI of the baseline contrast image. The method further includes acquiring (62) a next ultrasound contrast and tissue image pair, corresponding to an i th current contrast and tissue image pair. Frame-to-frame registration is established (64) between (i) the current tissue image and (ii) the baseline tissue image, the frame-to-frame registration being used (66) between the current tissue image and the baseline tissue image to transfer the ROI/VOI from (i) the baseline contrast image to (ii) the current contrast image, thereby creating a transformed ROI/VOI in the current contrast image. Quantitative analysis is then performed (68) on the transformed ROI/VOI of the current contrast image.

摘要翻译： 用于定量3D对比增强超声（CEUS）分析的方法（50）包括获取（54）初始对的超声对比度和解剖结构的组织图像。 在初始获取的组织图像中建立感兴趣区域（ROI）或感兴趣体积（VOI）（56），其变为基线组织图像。 建立的ROI / VOI从初始组织图像自动登记（58）到成为基线对比图像的初始对比图像。 对基线对比图像的ROI / VOI进行定量分析（60）。 该方法还包括获取（62）对应于第i个当前对比度和组织图像对的下一个超声对比度和组织图像对。 在（i）当前组织图像和（ii）基线组织图像之间建立帧对帧配准（64），使用当前组织图像和基线组织图像之间的帧对帧配准（66） 从（i）基线对比图像转移ROI / VOI到（ii）当前对比度图像，从而在当前对比度图像中创建变换的ROI / VOI。 然后对当前对比度图像的变换后的ROI / VOI进行定量分析（68）。

公开(公告)号：US10561462B2

公开(公告)日：2020-02-18

申请号：US13825353

申请日：2011-09-22

申请人： Sandeep Dalal ,  Jochen Kruecker

发明人： Sandeep Dalal ,  Jochen Kruecker

IPC分类号： A61B18/12 ,  A61B18/18 ,  A61B18/00 ,  A61B34/10 ,  A61B90/00 ,  A61B34/20

摘要： A system and method for ablation include ablating (508) a target volume using an ablation probe and collecting (510) temperature information around the target volume. A shape of an ablation volume is determined (512) based upon the temperature information. The shape is displayed (520) on a display relative to an image of the target volume.

公开(公告)号：US09144461B2

公开(公告)日：2015-09-29

申请号：US13131886

申请日：2009-11-05

申请人： Jochen Kruecker ,  Sandeep Dalal ,  Sheng Xu ,  Bradford J. Wood

发明人： Jochen Kruecker ,  Sandeep Dalal ,  Sheng Xu ,  Bradford J. Wood

IPC分类号： A61B18/14 ,  A61B18/18 ,  A61B18/12 ,  A61B19/00 ,  A61N7/02

CPC分类号： A61B18/18 ,  A61B18/1206 ,  A61B18/1477 ,  A61B18/1815 ,  A61B34/20 ,  A61B2018/1425 ,  A61B2034/104 ,  A61B2034/107 ,  A61B2034/2051 ,  A61B2090/378 ,  A61N7/02

摘要： A therapy planning and image guidance and navigation for an interventional procedure are combined in one system. The system includes: a radio frequency ablation therapy planning component (1) capable of creating an initial treatment plan, adjusting the treatment plan to take into account data received during a procedure and transferring a treatment plan to a navigation component, a navigation system component (2) to guide an ablation probe (6) and a feedback sub-system (3) for determining actual ablation probe positions/orientations and actual ablation size/shape via imaging (4) and/or tracking (5) systems, and enabling exchange of information between the planning component and the navigation component. By combining and integrating procedure planning and navigation, and by providing feedback from the navigation component back to the planning component about actual electrode position and orientation and ablation volume, complex procedures can be carried out more accurately, efficiently, and potentially with better clinical outcomes.

摘要翻译： 介入程序的治疗计划和图像引导和导航结合在一个系统中。 该系统包括：射频消融治疗计划组件（1），其能够创建初始治疗计划，调整治疗计划以考虑在手术期间接收的数据并将治疗计划转移到导航部件，导航系统组件（ 2）引导消融探针（6）和反馈子系统（3），用于通过成像（4）和/或跟踪（5）系统来确定实际消融探针位置/取向和实际消融尺寸/形状，以及使能交换 计划部件和导航部件之间的信息。 通过结合和整合程序规划和导航，并通过向导航组件提供关于实际电极位置和取向和消融量的规划组件的反馈，可以更准确，高效地，潜在地实现更好的临床结果。