摘要:
Provided is a compound having excellent dipeptidyl peptidase IV-inhibiting activity, and a remedy based on the activity for insulin-dependent diabetes (type 1 diabetes), especially for non insulin-dependent diabetes (type 2 diabetes), insulin-resistant disorders, and obesity.
摘要:
In the case where the living tissues in the patient's body is resected as well, it is possible to suture the resected portion immediately without replacement with another treatment device after resection. Thus, prevention of bleeding from the resected portion or earlier repair of an ulcer that occurs with the resected portion can be carried out for the patent lowly invasively and easily.
摘要:
An endoscopic treatment device is used with an endoscope. This treatment device includes a transmission member with a flexible structure having a distal end portion to be inserted into a body and can be operated outside the body, a push rod coupled to the distal end portion, and first and second connecting members rotatably coupled to the push rod. The treatment device further includes first and second arm members rotatably coupled to the distal end portion of the connecting member, a holding member rotatably holding the respective arm at a predetermined interval therebetween, and first and second actuating members integrally formed with the arm members and can open/close when the transmission member actuates the first and second connecting members and the first and second arm members through the push rod. This device also includes a needle mounted on at least one of the first and second actuating members.
摘要:
A method for determining human type III, IV and VI collagen peptides by way of enzyme immunoassay according to the sandwich technique using a monoclonal antibody and a polyclonal antibody each to the human type III, IV or VI collagen peptide, characterized in that the monoclonal antibody to the collagen peptide is used as an antibody to be coated onto a solid phase and/or an antibody to be labeled with an enzyme. Also disclosed is a sandwich technique using two different monoclonal antibodies. This method can be carried out with a smaller amount of samples in a simple manner to obtain a precise result and is thus useful for diagnosis of hepatic diseases.
摘要:
A treatment device for endoscopic therapy of the present invention includes a suturing-ligating member having a distal end portion and a proximal end portion, that carries out at least one of suturing and ligation of biological tissue, a stopper provided to be movable forward or backward on an proximal end side of the suturing or ligating member, and stoppable by friction on the suturing-ligating member to maintain the biological tissue in a sutured or ligated state by the suturing-ligating member, and a suturing-ligation releasing member provided movable with relative to the suturing-ligating member to release the suturing-ligation state maintained by firctional stopping between the suturing-ligating member and the stopper by moving the releasing member to the proximal end portion side of the suturing-ligating member.
摘要:
A medical ligating apparatus includes a medical ligating device having a member which is made of a flexible line and ligates living tissues, and a fixing member which is movably provided at the ligating member and fixes the living tissues in a ligated state, a manipulating device having a flexible sheath and a proximal manipulating section, and a cutting member for cutting the ligating member. The cutting member is provided on the manipulating device and is movably provided on the ligating member.
摘要:
The present invention provides a heater apparatus that divides a heater capacity (heater wire), connects the divided heater wire portions each other outside the heater, changes a connection mode outside irrespective of which of a 100 V system or a 200 V system is used as a supply voltage, and can thereby suppress a heater temperature to within a safe range even in a continuous current conduction mode, use a common heater and suppress management cost. Furthermore, since the heater wires are connected each other outside the heat insulating layer for the heater embedded in the heat insulating layer of the refrigerator, the present invention provides a heater apparatus capable of reducing production loss due to misconnections and using a common heater.
摘要:
An apparatus includes a crushing part which rotates and crushes the calculus, wherein a radius of rotation of the crushing part with respect to a rotation axis thereof increases or decreases in accordance with a rotation speed of the crushing part.
摘要:
There are provided a machine tool cooling system and cooling method which allow cost reduction by reducing the number of control valves, and in which opening/closing control is simple. The machine tool cooling system and cooling method include a hot oil tank 4 storing hot oil, a cold oil tank 5 storing cold oil, a first to third hot oil passages 9a to 9c and a first to third cold oil passages 10a to 10c, which supply the hot oil and the cold oil to a first to third heat generating portions 1 to 3, a hot oil return passage 11 returning the hot oil to the hot oil tank 4, a first to third supply control valves 16a to 16c interposed in the first to third cold oil passages 10a to 10c, and a valve controller 8 controlling opening/closing of the first to third supply control valves 16a to 16c so that the cold oil is supplied to the first to third heat generating portions 1 to 3 intermittently at different timings.
摘要:
There is provided a compound having a capsaicin receptor VR1 inhibitory activity and useful as a therapeutic agent for various pains including inflammatory pain and neurogenic pain, migraine, cluster headache, bladder diseases including overactive bladder, and the like.A benzamide derivative or a salt thereof wherein a benzene ring is attached to a D ring (a monocyclic or bicyclic hydrocarbon ring or a monocyclic or bicyclic heteroaromatic ring) through an amide bond, the benzene ring is directly bonded to an E ring (a monocyclic or bicyclic hydrocarbon ring or a monocyclic or bicyclic heteroaromatic ring), and the benzene ring is further bonded to A (an amino moiety, a monocyclic or bicyclic heterocycle) through L (a lower alkylene).