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    HERNIA PROSTHESIS WITH MARKING MEANS
    21.
    发明申请
    HERNIA PROSTHESIS WITH MARKING MEANS 审中-公开

    公开(公告)号：US20180243067A1

    公开(公告)日：2018-08-30

    申请号：US15963388

    申请日：2018-04-26

    Applicant: Sofradim Production

    Inventor： Sébastien Ladet ,  Sebastien Francois ,  Nicolas Prost

    IPC: A61F2/00

    Abstract: Prosthesis (1) comprising a patch (2) made of biocompatible material, said patch having a generally plane geometric shape that defines two opposite faces, a centre, a length and a width of said patch, characterized in that said patch is provided, on one (2a) of its faces, with a single marking means (3) designed to indicate both the centre (C) of the patch and also the longitudinal direction of said patch.

    SURGICAL FASTENERS AND METHODS FOR SEALING WOUNDS
    24.
    发明申请
    SURGICAL FASTENERS AND METHODS FOR SEALING WOUNDS 审中-公开
    外科紧固件和密封方法

    公开(公告)号：US20160166251A1

    公开(公告)日：2016-06-16

    申请号：US15048284

    申请日：2016-02-19

    Applicant: Sofradim Production

    Inventor： Sébastien Ladet

    IPC: A61B17/064 ,  A61L31/16 ,  A61L31/04

    CPC classification number: A61B17/0644 ,  A61B17/064 ,  A61B17/122 ,  A61B2017/00884 ,  A61L31/04 ,  A61L31/08 ,  A61L31/10 ,  A61L31/16

    Abstract: A method for closing a wound in tissue is provided which includes providing a surgical fastener having a plurality of reactive members of a specific binding pair attached on a surface of the surgical fastener, and providing tissue with a plurality of complementary reactive members of the specific binding pair, wherein upon contact of the reactive members on the surface of the surgical fastener with the complimentary reactive members on the tissue, covalent bonds are formed between the reactive members and the complementary reactive members, thus adhering the device to the tissue.

    Abstract translation: 提供了一种用于闭合组织中的伤口的方法，其包括提供外科紧固件，所述手术紧固件具有附接在手术紧固件的表面上的特定结合对的多个反应性构件，并且向组织提供特定结合物的多个互补的反应性成员 其中当外科紧固件的表面上的反应性构件与组织上的互补的反应构件接触时，在反应构件和互补的反应构件之间形成共价键，从而将该装置粘附到组织上。

    MEDICAL DEVICES INCORPORATING FUNCTIONAL ADHESIVES
    26.
    发明申请
    MEDICAL DEVICES INCORPORATING FUNCTIONAL ADHESIVES 有权
    包含功能性粘合剂的医疗器械

    公开(公告)号：US20140018849A1

    公开(公告)日：2014-01-16

    申请号：US14026149

    申请日：2013-09-13

    Applicant: Sofradim Production

    Inventor： Sébastien Ladet ,  Philippe Gravagna

    IPC: A61B17/00

    CPC classification number: A61B17/00491 ,  A61L15/22 ,  A61L15/58 ,  A61L31/04 ,  A61L31/14 ,  Y10T156/10

    Abstract: A method for bonding a polymeric medical device to tissue is provided which includes providing a polymeric medical device having a plurality of reactive members of a specific binding pair attached on a surface of the medical device, and providing tissue with a plurality of complementary reactive members of the specific binding pair, wherein upon contact of the reactive members on the surface of the medical device with the complimentary reactive members on the tissue, covalent bonds are formed between the reactive members and the complementary reactive members, thus adhering the device to the tissue. A kit is provided including a polymeric medical device such as a patch or mesh having a plurality of reactive members of a specific binding pair attached to a surface of the device and an applicator containing a solution or suspension of complementary reactive members of the specific binding pair, the complementary reactive members having a functionality that will adhere them to biological tissue upon contact, said applicator adapted to deliver the solution or suspension to biological tissue.

    Abstract translation: 提供了一种用于将聚合物医疗装置粘合到组织的方法，其包括提供聚合物医疗装置，其具有附着在医疗装置的表面上的特定结合对的多个反应性成员，并且向组织提供多个互补的反应性成员 特异性结合对，其中当在医疗装置的表面上的反应性构件与组织上的互补的反应性构件接触时，在反应性构件和互补的反应性构件之间形成共价键，从而将该装置粘附到组织上。 提供了一种试剂盒，其包括聚合物医疗装置，例如补片或网，其具有连接到装置的表面的特定结合对的多个反应性成员和包含特异性结合对的互补反应性成员的溶液或悬浮液的施用器 互补的活性成员具有在接触时将它们粘附到生物组织上的功能，所述施用器适于将溶液或悬浮液输送到生物组织。

    Process for preparing a porous layer
    27.
    发明授权
    Process for preparing a porous layer 有权

    公开(公告)号：US10253152B2

    公开(公告)日：2019-04-09

    申请号：US14423150

    申请日：2013-09-26

    Applicant: Sofradim Production

    Inventor： Sébastien Ladet ,  Nicolas Prost

    IPC: B05B3/00 ,  C08J9/28 ,  A61L27/20 ,  C08J5/18 ,  A61L31/04 ,  A61L31/14

    Abstract: The present invention relates to a process for preparing a porous layer of biocompatible polymer, having a uniform density and porosity, comprising the following steps: a) a quantity Qp of solution of the said polymer, having a viscosity Vp, is poured into a mold in order to form a first sublayer, the surface of the first sublayer being left to the open air; b) a quantity Qs of solvent, having a viscosity Vs, lower than Vp, is spread uniformly over the surface of the first sublayer so as to form a second sublayer; c) the first and second sublayers are subjected to a step of lyophilization, in which the said polymer is a polysaccharide chosen from hyaluronic acid, alginic acid and chitosan, salts thereof and mixtures thereof.

    METHOD FOR PREPARING A CHITOSAN-BASED POROUS LAYER
    30.
    发明申请
    METHOD FOR PREPARING A CHITOSAN-BASED POROUS LAYER 审中-公开
    制备基于多晶硅的多孔层的方法

    公开(公告)号：US20150158209A1

    公开(公告)日：2015-06-11

    申请号：US14413499

    申请日：2013-08-01

    Applicant: Sofradim Production

    Inventor： Sébastien Ladet ,  Sebastien Francois ,  Julien Claret ,  Maud Buffin

    IPC: B29C43/02 ,  A61L27/56 ,  A61L27/20

    CPC classification number: B29C43/02 ,  A61B17/07292 ,  A61L27/20 ,  A61L27/50 ,  A61L27/56 ,  B29K2005/00 ,  B29L2007/00 ,  C08J9/28 ,  C08J2201/0504 ,  C08J2305/08 ,  C08L5/08

    Abstract: Method for preparing a chitosan-based porous layer The present invention relates to a method or preparing a chitosan-based, neutralized compressed porous layer, comprising the following steps: —a) a chitosan solution is prepared, —b) said solution is poured into a mould in order to form a layer, —c) the layer obtained in b) is lyophilized so as to obtain a porous layer, —d) said porous layer obtained in c) is compressed, —e) the compressed porous layer obtained in d) is neutralized by means of an NH4OH solution. It also relates to an implant comprising a layer obtained according to such a method.

    Abstract translation: 制备壳聚糖基多孔层的方法本发明涉及一种制备基于壳聚糖的中和的压缩多孔层的方法或方法，包括以下步骤：a）制备壳聚糖溶液，-b）将所述溶液倒入 为了形成层，将c）b）中获得的层冻干，以得到多孔层，-d）将c）中得到的多孔层压缩，-e）将得到的压缩多孔层 d）通过NH 4 OH溶液中和。 它还涉及包括根据这种方法获得的层的植入物。

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