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64 条记录 (耗时 0.04 秒)

    Combination toy building block and container for holding liquids and the like
    21.
    发明授权
    Combination toy building block and container for holding liquids and the like 失效
    组合玩具积木和容纳液体的容器等

    公开(公告)号：US07175498B2

    公开(公告)日：2007-02-13

    申请号：US10703734

    申请日：2003-11-07

    申请人： Scott Garpow ,  Thomas Harris

    发明人： Scott Garpow ,  Thomas Harris

    IPC分类号： A63H33/04

    CPC分类号： E04B2/08 ,  A63H33/08 ,  B65D81/361 ,  E04B2002/0223

    摘要： A combination toy building block and container for holding liquids and the like, wherein the functional configuration of the device permits both the carrying of a dispensable substance and the stacking of multiple containers, thereby enabling the imaginative play construction of buildings and objects such as, but not limited to, play forts, play houses, play cars and boats, statues, tables and chairs.

    摘要翻译： 一种用于保持液体等的组合玩具积木和容器，其中该装置的功能构型允许携带可分配物质和多个容器的堆叠，从而使建筑物和物体（例如，但是 不限于玩堡垒，玩房屋，玩汽车和小船，雕像，桌椅。

    Bicomponent fiber wick
    25.
    发明申请
    Bicomponent fiber wick 有权
    双组分纤维灯芯

    公开(公告)号：US20050189292A1

    公开(公告)日：2005-09-01

    申请号：US10790494

    申请日：2004-03-01

    申请人： Bennett Ward ,  David Harris ,  Jian Xiang ,  Thomas Harris

    发明人： Bennett Ward ,  David Harris ,  Jian Xiang ,  Thomas Harris

    IPC分类号： B01D39/02 ,  B01D39/04

    CPC分类号： B01D39/04 ,  Y10S428/903 ,  Y10T428/2929 ,  Y10T428/2947 ,  Y10T442/2525

    摘要： A bicomponent fiber wick is provided for use in processing an analyte fluid. The bicomponent fiber wick comprises a self-sustaining, fluid transmissive body comprising a plurality of bundled, crimped, bicomponent fibers bonded to each other at spaced apart contact points. Each bicomponent fiber has a fiber structure comprising a first fiber component formed from a polyamide material and a second fiber component. The fibers collectively define tortuous fluid flow paths through the fluid transmissive body, the fiber structure being configured for controlling flow of the analyte fluid through the fluid transmissive body with at least a portion of the first fiber component in contact with the analyte fluid.

    摘要翻译： 提供了一种双组分纤维芯，用于处理分析物流体。 双组分纤维芯包括一个自持的流体传输体，其包括在间隔开的接触点处彼此结合的多个捆扎的卷曲的双组分纤维。 每个双组分纤维具有包含由聚酰胺材料形成的第一纤维部件和第二纤维部件的纤维结构。 所述纤维共同地限定通过流体传输体的曲折的流体流动路径，所述纤维结构构造成用于控制分析物流体通过流体传输体的流动，其中第一纤维组分的至少一部分与分析物流体接触。

    Vitronectin receptor antagonist pharmaceuticals
    26.
    发明申请
    Vitronectin receptor antagonist pharmaceuticals 失效
    Vitronectin受体拮抗剂药物

    公开(公告)号：US20050154185A1

    公开(公告)日：2005-07-14

    申请号：US10770380

    申请日：2004-02-02

    申请人： Milind Rajopadhye ,  Thomas Harris ,  Edward Cheesman

    发明人： Milind Rajopadhye ,  Thomas Harris ,  Edward Cheesman

    IPC分类号： A61K49/00 ,  C07D401/12 ,  C07D401/14 ,  C07K5/02 ,  C07K5/06 ,  C07K5/078 ,  C07K5/12 ,  C07D471/02 ,  C07D487/02

    CPC分类号： C07D401/14 ,  A61K49/0002 ,  C07D401/12 ,  C07K5/0205 ,  C07K5/0215 ,  C07K5/06139 ,  C07K5/06191

    摘要： The present invention describes novel compounds of the formula: (Q)d-Ln-Ch, useful for the diagnosis and treatment of cancer, methods of imaging tumors in a patient, and methods of treating cancer in a patient. The present invention also provides novel compounds useful for monitoring therapeutic angiogenesis treatment and destruction of new angiogenic vasculature. The present invention also provides novel compounds useful for imaging atherosclerosis, restenosis, cardiac ischemia, and myocardial reperfusion injury. The present invention also provides novel compounds useful for the treatment of rheumatoid arthritis. The pharmaceuticals are comprised of a targeting moiety that binds to a receptor that is upregulated during angiogenesis, an optional linking group, and a therapeutically effective radioisotope or diagnostically effective imageable moiety. The imageable moiety is a gamma ray or positron emitting radioisotope, a magnetic resonance imaging contrast agent, an X-ray contrast agent, or an ultrasound contrast agent.

    摘要翻译： 本发明描述了新的下式化合物：<？in-line-formula description =“In-line Formulas”end =“lead”？>（Q） 对于癌症的诊断和治疗有用的<？in-line-formula description =“在线公式”end =“tail”？>，肿瘤成像方法 患者，以及在患者中治疗癌症的方法。 本发明还提供了可用于监测治疗性血管生成治疗和破坏新的血管生成脉管系统的新型化合物。 本发明还提供了用于成像动脉粥样硬化，再狭窄，心脏缺血和心肌再灌注损伤的新型化合物。 本发明还提供了可用于治疗类风湿性关节炎的新化合物。 药物由与血管发生期间上调的受体结合的靶向部分，任选的连接基团和治疗有效的放射性同位素或诊断上有效的可成像部分组成。 可成像部分是伽马射线或正电子发射放射性同位素，磁共振成像造影剂，X射线造影剂或超声造影剂。

    Compounds containing matrix metalloproteinase substrates and methods of their use
    28.
    发明申请
    Compounds containing matrix metalloproteinase substrates and methods of their use 审中-公开
    含有基质金属蛋白酶底物的化合物及其使用方法

    公开(公告)号：US20050106100A1

    公开(公告)日：2005-05-19

    申请号：US10931627

    申请日：2004-09-01

    申请人： Thomas Harris ,  Padmaja Yalamanchili

    发明人： Thomas Harris ,  Padmaja Yalamanchili

    IPC分类号： A61K49/00 ,  A61K51/00 ,  A61K51/08 ,  C07K16/46

    CPC分类号： A61K51/0495 ,  A61K49/0002 ,  A61K51/08

    摘要： Compounds for use in a diagnostic agent for detecting, imaging, and/or monitoring a pathological disorder associated with matrix metalloproteinase activity at a site of interest in a patient are disclosed. Compositions and kits containing the compounds are also disclosed. In addition, methods of detecting, imaging, and/or monitoring the presence of matrix metalloproteinase or a pathological disorder associated with matrix metalloprotainase activity in a patient are disclosed.

    摘要翻译： 公开了用于诊断用于检测，成像和/或监测与患者感兴趣部位的基质金属蛋白酶活性相关的病理学障碍的化合物。 还公开了含有这些化合物的组合物和试剂盒。 此外，公开了检测，成像和/或监测基质金属蛋白酶的存在或与患者中的基质金属蛋白酶活性相关的病理学障碍的方法。

    Concrete mixing drum cleanout apparatus and method
    30.
    发明申请
    Concrete mixing drum cleanout apparatus and method 审中-公开
    混凝土搅拌筒清洗装置及方法

    公开(公告)号：US20070086270A1

    公开(公告)日：2007-04-19

    申请号：US11252144

    申请日：2005-10-17

    申请人： Thomas Harris ,  Aaron Meyer

    发明人： Thomas Harris ,  Aaron Meyer

    IPC分类号： B28C5/42

    CPC分类号： B28C5/4203 ,  B08B9/08 ,  B08B9/0813

    摘要： An integrally mounted apparatus for washing out vehicle-mounted concrete mixing drums is disclosed. The washout apparatus includes an open-ended elongate, relatively rigid shaped hollow guide tube mounted in fixed relation to the support structure support of an inclined mixing drum and extending in fixed relation to the open end of the drum between the fins and charge hopper. A flexible hollow hose is threaded through the guide tube. The hose has a receiving end connected with a source of cleaning fluid under pressure and a discharge end which protrudes from the end of the guide tube as it ends inside the open end of the mixing drum. A forward hose stop is provided for preventing the hose from slipping back down through the guide tube and a rear hose stop is provided for limiting the travel of the discharge end of the hose outward from the end of the guide tube.

    摘要翻译： 公开了一种用于清洗车载混凝土搅拌筒的整体安装的装置。 冲洗装置包括开口的细长相对刚性的中空导管，其以倾斜的混合鼓的支撑结构支撑件固定的关系安装，并且在固定的关系上延伸到在翅片和充电料斗之间的滚筒的开口端。 柔性中空软管穿过导管。 软管具有与压力下的清洁流体源连接的接收端以及当引导管的端部在混合鼓的开口端内部时突出的排出端。 提供一个前向软管止挡件，用于防止软管通过引导管向下滑动，并且提供一个后软管止动件，用于限制软管的排放端从引导管的端部向外的行进。