INJECTION METHOD FOR MICROFLUIDIC CHIPS
    22.
    发明申请
    INJECTION METHOD FOR MICROFLUIDIC CHIPS 有权
    微流感注射液的注射方法

    公开(公告)号:US20100155244A1

    公开(公告)日:2010-06-24

    申请号:US12341233

    申请日:2008-12-22

    IPC分类号: B01D57/02

    CPC分类号: B01D57/02

    摘要: Methods and systems for injecting a sample during electrophoresis, that generally comprise: loading a sieving matrix through a first end of a separation channel; having the an end of the sieving matrix at a set distance from the intersection of the separation channel and a loading channel; pressure loading a sample through the loading channel and filling an empty portion of the separation channel; applying an electric field across the separation channel while flowing a washing buffer through the loading channel; and injecting a portion of the sample into the separation channel, wherein the portion of the sample injected is of a size that is determined by a distance between the end of the sieving matrix and the intersection of the loading and separation channels.

    摘要翻译: 用于在电泳期间注射样品的方法和系统,其通常包括:通过分离通道的第一端装载筛分基质; 筛分矩阵的结束距离分离通道和加载通道的交点处一定距离; 通过加载通道加载样品并填充分离通道的空的部分; 在使洗涤缓冲液流过所述装载通道的同时,在所述分离通道上施加电场; 以及将所述样品的一部分注入所述分离通道中,其中所述注入的所述样品的所述部分具有由所述筛分矩阵的末端与所述加载和分离通道的交点之间的距离确定的尺寸。

    Injection method for microfluidic chips
    23.
    发明授权
    Injection method for microfluidic chips 失效
    微流控芯片注射方法

    公开(公告)号:US07740747B2

    公开(公告)日:2010-06-22

    申请号:US11965794

    申请日:2007-12-28

    IPC分类号: G01N27/26

    CPC分类号: G01N27/44743

    摘要: A microchip for capillary electrophoresis is provided. The microchip comprises an injection channel and a separation channel configured to receive a sample through a sample well disposed on a first end of the separation channel; wherein the injection channel and the separation channel intersect to form a ‘T’ junction. The microchip further comprises a first valve disposed adjacent to the ‘T’ junction and on the separation channel and a second valve disposed at the ‘T’ junction. The second valve is a two-way valve. A sample plug is injected into an area between the ‘T’ junction and a second end of the separation channel.

    摘要翻译: 提供了用于毛细管电泳的微芯片。 微芯片包括注入通道和分离通道,其被配置为通过设置在分离通道的第一端上的样品阱接收样品; 其中注入通道和分离通道相交以形成“T”结。 微芯片还包括邻近'T'结和在分离通道上设置的第一阀和设置在'T'结处的第二阀。 第二个阀是一个二通阀。 将样品塞注入到“T”结和分离通道的第二端之间的区域中。

    Optofluidic devices and methods of using the same
    24.
    发明授权
    Optofluidic devices and methods of using the same 失效
    光电装置及其使用方法

    公开(公告)号:US07574089B1

    公开(公告)日:2009-08-11

    申请号:US11400947

    申请日:2006-04-10

    IPC分类号: G02B6/00 G02B6/02 G02B6/10

    摘要: An optofluidic device is provided. The device includes a cladding region having a first refractive index, and a channel defined by the cladding region such that the cladding region forms an inner surface or an interface of the channel. The channel is configured to house one or more of a liquid, a solid, a gas, a colloidal, or a suspension sample, wherein the sample has a second refractive index, where the channel is configured to guide radiation, and where the first refractive index is lower than the second refractive index.

    摘要翻译: 提供了一种光流体装置。 该器件包括具有第一折射率的包层区域和由包层区域限定的沟道,使得包层区域形成沟道的内表面或界面。 通道被配置成容纳液体,固体,气体,胶体或悬浮样品中的一种或多种,​​其中样品具有第二折射率,其中通道被构造成引导辐射,并且其中第一折射 指数低于第二折射率。

    MICROFLUIDIC DEVICE WITH VERTICAL INJECTION APERTURE
    26.
    发明申请
    MICROFLUIDIC DEVICE WITH VERTICAL INJECTION APERTURE 有权
    具有垂直注射孔的微流体装置

    公开(公告)号:US20090071832A1

    公开(公告)日:2009-03-19

    申请号:US11857570

    申请日:2007-09-19

    IPC分类号: G01N27/26

    CPC分类号: G01N27/447

    摘要: A microfluidic device with a vertical injection aperture is provided. The microfluidic device comprises a separation channel, an injection aperture disposed adjacent to and in fluid communication with the separation channel. The microfluidic device further comprises a semi-permeable filter disposed adjacent to the injection aperture, wherein the filter is configured to preconcentrate a sample in the injection aperture to form a preconcentrated sample plug during an injection operation, and wherein the sample plug flows downwardly from the injection aperture to the separation channel during an electrophoresis operation.

    摘要翻译: 提供具有垂直注射孔的微流体装置。 微流体装置包括分离通道,与分离通道相邻并且与分离通道流体连通地设置的注射孔。 微流体装置还包括邻近喷射孔布置的半渗透过滤器,其中过滤器构造成在注射操作期间预浓缩注入孔中的样品以形成预浓缩样品塞,并且其中样品塞从 在电泳操作期间到分离通道的注射孔径。

    Method of wet etching vias and articles formed thereby
    27.
    发明授权
    Method of wet etching vias and articles formed thereby 失效
    湿法蚀刻通孔和​​由此形成的制品的方法

    公开(公告)号:US07365437B2

    公开(公告)日:2008-04-29

    申请号:US11337249

    申请日:2006-01-23

    IPC分类号: H01L29/40

    摘要: A method for forming smooth walled, prismatically-profiled through-wafer vias and articles formed through the method. An etch stop material is provided on a wafer, which may be a silicon wafer. A mask material is provided on the etch stop material and patterned in such a way as to lead to the formation of vias that have at least one pair of opposing side walls that run parallel to a plane in the wafer. A wet etchant, such as potassium hydroxide, is used to etch vias in the wafer. The use of a wet etchant leads to the formation of smooth side walls. This method allows an aspect ratio of height versus width of the vias of greater than 75 to 1.

    摘要翻译: 用于形成通过该方法形成的平滑壁,棱镜通孔晶片通孔和制品的方法。 在晶片上提供蚀刻停止材料,晶片可以是<110>硅晶片。 在蚀刻停止材料上提供掩模材料,并以这样的方式图案化,以便导致形成通孔,其具有平行于晶片中的111平面延伸的至少一对相对的侧壁。 使用诸如氢氧化钾的湿蚀刻剂来蚀刻晶片中的通孔。 使用湿蚀刻剂导致形成平滑的侧壁。 该方法允许通孔的高度与宽度的长宽比大于75至1。

    MICRO-ELECTROMECHANICAL SYSTEM (MEMS) BASED CURRENT & MAGNETIC FIELD SENSOR HAVING CAPACITIVE SENSE COMPONENTS
    28.
    发明申请
    MICRO-ELECTROMECHANICAL SYSTEM (MEMS) BASED CURRENT & MAGNETIC FIELD SENSOR HAVING CAPACITIVE SENSE COMPONENTS 有权
    基于微电子系统(MEMS)的电流和具有电容感测元件的磁场传感器

    公开(公告)号:US20080070338A1

    公开(公告)日:2008-03-20

    申请号:US11939589

    申请日:2007-11-14

    IPC分类号: H01L21/02

    摘要: A micro-electromechanical system (MEMS) based current & magnetic field sensor includes a MEMS-based magnetic field sensing component having a capacitive magneto-MEMS component, a compensator and an output component for sensing magnetic fields and for providing, in response thereto, an indication of the current present in a respective conductor to be measured. In one embodiment, first and second mechanical sense components are electrically conductive and operate to sense a change in a capacitance between the mechanical sense components in response to a mechanical indicator from a magnetic-to-mechanical converter.

    摘要翻译: 基于微机电系统(MEMS)的电流和磁场传感器包括具有电容式磁MEMS组件的基于MEMS的磁场感测部件,补偿器和用于感测磁场的输出部件,并且响应于此而提供 当前存在于待测量的导体中的指示。 在一个实施例中,第一和第二机械感测部件是导电的并且用于响应于来自磁 - 机械转换器的机械指示器感测机械感测部件之间的电容的变化。