公开(公告)号：US09362712B1

公开(公告)日：2016-06-07

申请号：US14812350

申请日：2015-07-29

Applicant: Mansoor Sheik-Bahae ,  Richard I. Epstein

Inventor： Mansoor Sheik-Bahae ,  Richard I. Epstein

IPC: H01S3/13 ,  H01S3/106 ,  H01S3/16 ,  H01S3/042 ,  H01S3/137 ,  H01S3/131 ,  H01S3/04

CPC classification number: H01S3/04 ,  H01S3/0401 ,  H01S3/0408 ,  H01S3/13 ,  H01S3/1304 ,  H01S3/1305 ,  H01S3/1317 ,  H01S3/137 ,  H01S3/1392 ,  H01S3/1618 ,  H01S3/1653

Abstract: Provided is a method and system for stabilizing a property of a first laser beam from a first laser in a vibration-free and cryogen free-manner. The method can include optically cooling a ytterbium-doped yttrium lithium fluoride (Yb:YLF) crystal using a second laser beam; coupling the crystal to a thermal coupling, wherein the thermal coupling is further coupled to a reference cavity to maintain a temperate of the reference cavity; directing a portion of the first laser beam through the reference cavity onto a photodetector to measure the property of the first laser beam; and stabilizing the first laser beam using a feedback control mechanism using the photodetector.

Abstract translation: 提供一种用于以无振动和无冷冻的方式稳定来自第一激光器的第一激光束的性质的方法和系统。 该方法可以包括使用第二激光束光学冷却掺杂镱的钇氟化锂（Yb：YLF）晶体; 将所述晶体耦合到热耦合，其中所述热耦合进一步耦合到参考腔以保持所述参考腔的温度; 将第一激光束的一部分引导通过参考腔到光电检测器上以测量第一激光束的性质; 以及使用所述光电检测器的反馈控制机构稳定所述第一激光束。

公开(公告)号：US09354062B2

公开(公告)日：2016-05-31

申请号：US13987911

申请日：2013-09-16

Applicant: Marek A. Osinski ,  Petr G. Eliseev ,  Edward W. Taylor

Inventor： Marek A. Osinski ,  Petr G. Eliseev ,  Edward W. Taylor

IPC: G01C19/72 ,  H01S3/102 ,  G02F1/35 ,  G01C19/66

CPC classification number: G01C19/727 ,  G01C19/66 ,  G02F1/3519 ,  H01S3/1028 ,  H01S5/1071 ,  H01S5/4068

Abstract: Method and apparatus embody a rotation sensor including one or more ring lasers designed to utilize a nonlinear Sagnac effect, a passive waveguide arrangement, and a photodetector arrangement to receive the outcoupled light and to detect rotation of the sensor; wherein these components are arranged into a monolithically integrated optoelectronic integrated circuit on a single substrate. The method and apparatus can include seeding a stable, rotation -insensitive, strong (driving) wave using a single-frequency edge emitting laser monolithically integrated on the same substrate.

Abstract translation: 方法和装置包括旋转传感器，其包括设计成利用非线性Sagnac效应的一个或多个环形激光器，无源波导装置和用于接收输出耦合的光并检测传感器的旋转的光电检测器装置; 其中这些部件被布置在单个基板上的单片集成光电集成电路中。 该方法和装置可以包括使用单一集成在同一衬底上的单频边缘发射激光器接种稳定的，旋转敏感的强（驱动）波。

公开(公告)号：US20160130148A1

公开(公告)日：2016-05-12

申请号：US14900697

申请日：2014-07-01

Applicant: Alexey SEROV ,  Plamen B. ATANASSOV ,  Nalin ANDERSEN

Inventor： Alexey Serov ,  Plamen B Atanassov ,  Nalin Andersen

IPC: C01B31/04 ,  H01M10/0525 ,  H01M4/36 ,  B01J21/18

CPC classification number: H01M10/0525 ,  B01J21/18 ,  B01J23/40 ,  B01J23/56 ,  B01J23/8926 ,  B01J35/0013 ,  B01J37/084 ,  C01B32/184 ,  C01B2204/02 ,  C01B2204/04 ,  H01M4/362

Abstract: Novel non-planar non-contiguous graphene structures and novel methods for forming the same. According to some embodiments the novel methods result in three-dimensional graphene structures. According to a further embodiment these three-dimensional graphene structures have a specific, controlled morphology. According to a still further method the novel method results in decoratable graphene sheets or three-dimensional graphene structures.

Abstract translation: 新型非平面非连续石墨烯结构及其形成方法。 根据一些实施方案，新方法产生三维石墨烯结构。 根据另一个实施方案，这些三维石墨烯结构具有特定的受控形态。 根据另一种方法，该新方法产生可装饰的石墨烯片或三维石墨烯结构。

公开(公告)号：US09306363B1

公开(公告)日：2016-04-05

申请号：US13253386

申请日：2011-10-05

Applicant: Alexandre B. Braga ,  Jean-Claude Diels ,  Ronald R. Kay

Inventor： Alexandre B. Braga ,  Jean-Claude Diels ,  Ronald R. Kay

IPC: G01B7/30 ,  G01B7/14 ,  H01S3/067 ,  G01B7/00

CPC classification number: H01S3/06791 ,  G01B7/003 ,  H01S3/06712 ,  H01S3/06725 ,  H01S3/094003 ,  H01S3/09415 ,  H01S3/1067 ,  H01S3/1109 ,  H01S3/1121 ,  H01S3/1304 ,  H01S3/1305 ,  H01S3/1307 ,  H01S3/136 ,  H01S3/1608

Abstract: In various embodiments, systems and methods can be structured to provide efficient active bidirectional mode-locked lasers, which can be used as intracavity phase interferometer (IPI) sensors. Stable bidirectional mode-locking can be achieved by a combination of a passive mechanism, a passively driven active mechanism, and a beat note detection system. Such systems can be used in guidance, navigation, and control systems, where attitude control of a vehicle relies on accurate measurements of its position and motion. In various embodiments, a detection system can be based on an all fiber intracavity phase interferometer (IPI) active laser capable of delivering accurate simultaneous measurements of all three degrees of rotation and position in a single, compact, cost effective unit. A variation of the same system can include a linear cavity laser for accurate measurements of acceleration without the use of any inertial masses. Additional apparatus, systems, and methods are disclosed.

Abstract translation: 在各种实施例中，可以将系统和方法构造成提供有效的主动双向锁模激光器，其可以用作腔内相位干涉仪（IPI）传感器。 可以通过被动机构，被动驱动的主动机构和节拍检测系统的组合来实现稳定的双向锁模。 这样的系统可以用在导向，导航和控制系统中，其中车辆的姿态控制依赖于其位置和运动的准确测量。 在各种实施例中，检测系统可以基于全光纤腔内相位干涉仪（IPI）有源激光器，其能够在单个，紧凑，成本有效的单元中提供所有三个旋转角度和位置的精确同时测量。 相同系统的变型可以包括用于在不使用任何惯性质量的情况下精确地测量加速度的线性腔激光器。 公开了附加装置，系统和方法。

公开(公告)号：US09260311B1

公开(公告)日：2016-02-16

申请号：US14539294

申请日：2014-11-12

Applicant: Dimiter N Petsev ,  Amber Ortiz ,  Nick Carroll ,  Plamen B Atanassov ,  Svitlana Pylypenko

Inventor： Dimiter N Petsev ,  Amber Ortiz ,  Nick Carroll ,  Plamen B Atanassov ,  Svitlana Pylypenko

IPC: C01B33/18

CPC classification number: C01B33/18 ,  B01F3/0807 ,  B01F13/0062 ,  C01P2004/03 ,  C01P2004/04 ,  C01P2004/32 ,  C01P2006/16 ,  C01P2006/17 ,  Y10T428/2982 ,  Y10T428/2991

Abstract: According to various embodiments the present disclosure provides porous particles and methods and apparatus for forming porous microparticles. According to a specific embodiment, the present disclosure provides microparticles with multi-nodal porosity and methods for forming the same. According to a still further embodiment, the present disclosure provides microfluidic device-based methods for forming microparticles with multi-nodal nanoporosity. Furthermore, the present disclosure provides populations of monosdisperse mesoporous microparticles with multi-nodal nanoporosity and methods and apparatus for forming the same. According to a specific embodiment, the present disclosure provides populations of monodisperse mesoporous microparticles formed using a microfluidic device.

Abstract translation: 根据各种实施方案，本公开提供了用于形成多孔微粒的多孔颗粒和方法和装置。 根据具体实施方式，本公开内容提供具有多节点孔隙率的微粒及其形成方法。 根据另外的实施方案，本公开提供了用于形成具有多节点纳米孔隙度的微粒的基于微流体装置的方法。 此外，本公开提供了具有多节点纳米孔隙度的单分散介孔微粒的群体以及用于形成其的方法和装置。 根据具体实施方案，本公开提供使用微流体装置形成的单分散中孔微粒的群体。

公开(公告)号：US09259415B2

公开(公告)日：2016-02-16

申请号：US13773871

申请日：2013-02-22

Applicant: Susan A. McDowell ,  Robert E. Sammelson ,  Larry A. Sklar ,  Mark K. Haynes

Inventor： Susan A. McDowell ,  Robert E. Sammelson ,  Larry A. Sklar ,  Mark K. Haynes

IPC: A61K31/415 ,  A61K31/63 ,  A61K31/635

CPC classification number: A61K31/415 ,  A61K31/63 ,  A61K31/635

Abstract: The present disclosure relates to molecules which function as selective modulators (i.e., inhibitors and agonists) of the Ras-homologous (Rho) family of small GTPases and, in particular, CDC42 GTPase, and their use to treat bacterial infection including systemic infection from sources such as Staphylococcus aureus.

Abstract translation: 本公开内容涉及用作小GTP酶的Ras同源（Rho）家族，特别是CDC42GTP酶的选择性调节剂（即抑制剂和激动剂）的分子及其用于治疗细菌感染的用途，包括来源的全身感染 如金黄色葡萄球菌。

公开(公告)号：US09239455B2

公开(公告)日：2016-01-19

申请号：US13629598

申请日：2012-09-27

Applicant: Steven R. J. Brueck ,  Alexander Neumann ,  Yuliya Kuznetsova

Inventor： Steven R. J. Brueck ,  Alexander Neumann ,  Yuliya Kuznetsova

IPC: G02B21/06 ,  G02B21/00 ,  G02B21/36 ,  G06T3/40 ,  G01N21/65

CPC classification number: G02B21/06 ,  G01N2021/653 ,  G02B21/0056 ,  G02B21/365 ,  G06T3/4061

Abstract: In accordance with the aspects of the present disclosure, a method and apparatus is disclosed for imaging interferometric microscopy (IIM), which can use an immersion medium to enhance resolution up to a resolution of linear systems resolution limit of λ/4n, where λ is the wavelength in free space and n is the index of refraction of a transmission medium.

Abstract translation: 根据本公开的方面，公开了一种用于成像干涉显微镜（IIM）的方法和装置，其可以使用浸没介质来增强分辨率，直到λ/ 4n的线性系统分辨率极限的分辨率，其中λ是 自由空间中的波长和n是传输介质的折射率。

公开(公告)号：US20150380741A1

公开(公告)日：2015-12-31

申请号：US14767038

申请日：2014-02-11

Applicant: Alexey SEROV ,  Plamen B ATANASSOV

Inventor： Alexey Serov ,  Plamen B Atanassov

IPC: H01M4/86 ,  H01M4/90 ,  H01M4/88 ,  H01M4/92

CPC classification number: H01M4/8605 ,  H01M4/8803 ,  H01M4/8817 ,  H01M4/8825 ,  H01M4/8842 ,  H01M4/885 ,  H01M4/8882 ,  H01M4/9008 ,  H01M4/9075 ,  H01M4/921 ,  H01M4/925 ,  H01M2250/10 ,  H01M2250/20 ,  H01M2250/30 ,  Y02B90/14 ,  Y02B90/18 ,  Y02T90/32

Abstract: Novel active supports, novel catalysts, and methods of preparing active supports using a sacrificial template particles and methods of preparing the same are all described.

Abstract translation: 新型活性载体，新型催化剂和使用牺牲模板颗粒制备活性载体的方法及其制备方法都有描述。

公开(公告)号：US20150364784A1

公开(公告)日：2015-12-17

申请号：US14760275

申请日：2014-01-13

Applicant: Sofiya Malinova BABANOVA ,  Plamen B. ATANASSOV

Inventor： Sofiya Malinova Babanova ,  Plamen B Atanassov

IPC: H01M8/16

CPC classification number: H01M8/16 ,  H01M4/90 ,  H01M4/9008 ,  Y02E60/527

Abstract: A biofuel cell comprising an anode and cathode wherein biocatalytic enzymes are purposefully oriented at each side of the fuel cell so as to increase and/or optimize the enzymes' performance in catalysis and/or electron transfer.

Abstract translation: 一种包含阳极和阴极的生物燃料电池，其中生物催化酶有目的地定向在燃料电池的每一侧，以便增加和/或优化酶在催化和/或电子转移中的性能。

公开(公告)号：US09173692B1

公开(公告)日：2015-11-03

申请号：US13918949

申请日：2013-06-15

Applicant: STC.UNM

Inventor： Paul E. Kaloostian

IPC: A61B17/86 ,  A61B17/00 ,  A61B17/68

CPC classification number: A61B17/864 ,  A61B17/68 ,  A61B17/7002 ,  A61B17/702 ,  A61B17/7035 ,  A61B17/7037 ,  A61B17/7098 ,  A61B17/80 ,  A61B17/8605 ,  A61B17/8615 ,  A61B17/8625 ,  A61B17/866 ,  A61B17/8685 ,  A61B17/8841 ,  A61B2017/00933 ,  A61B2017/00964 ,  A61F2/44 ,  A61F2002/2835 ,  A61F2002/30405 ,  A61F2002/3055 ,  A61F2002/30601 ,  A61F2002/30784 ,  A61F2002/30787 ,  A61F2310/00023 ,  A61F2310/00359 ,  A61F2310/00958 ,  A61F2310/0097

Abstract: Composite orthopedic devices that facilitate spine stabilization, such as: bone screws, rods, plates, interbodies, and corpectomy cages are disclosed. They are designed to provide both strength and load carrying capabilities, while increasing bio-integration of the devices with the surrounding bone tissue. They are constructed of composite layers of allograft and/or autograft bone and a structural material, such as titanium alloy or carbon/graphite fiber composite. Cannulations within the device are loaded with a mixture of stem cells, particles of allograft and/or autograft bone, and bone growth factors, such as BMP-2. The cannulations are connected to the surface of the device via multiple fenestrations that provide pathways to supply the bone/stem cell mixture to the surface, allowing living bone tissue to grow and insure bio-integration. The devices can also have radiofrequency (RF) stimulation implantation within the structure of the implanted device, capable of responding to external RF stimulation of enhanced bone growth.

Abstract translation: 公开了促进脊柱稳定的复合矫形装置，例如：骨螺钉，杆，板，中间体和椎骨切除术笼。 它们旨在提供强度和负载能力，同时增加设备与周围骨组织的生物整合。 它们由同种异体移植物和/或自体骨的复合层和诸如钛合金或碳/石墨纤维复合材料的结构材料构成。 装置内的装置装载有干细胞，同种异体移植物和/或自体骨的颗粒和骨生长因子如BMP-2的混合物。 插管通过多个窗口连接到装置的表面，这些开窗提供将骨/干细胞混合物提供给表面的途径，允许活骨组织生长并确保生物整合。 该装置还可以在植入装置的结构内具有射频（RF）刺激植入，能够响应增强的骨生长的外部RF刺激。