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    Method for Preparing High-Content Food-Grade Zeaxanthin
    34.
    发明申请
    Method for Preparing High-Content Food-Grade Zeaxanthin 有权
    高含量食品级玉米黄质的制备方法

    公开(公告)号：US20080081932A1

    公开(公告)日：2008-04-03

    申请号：US11857248

    申请日：2007-09-18

    Applicant: Xinde Xu ,  Lihua Zhang ,  Boqiu Chen ,  Di Zhou ,  Shuangming Ye ,  Chiyu Ding ,  Hongping Lv ,  Bin Shao

    Inventor： Xinde Xu ,  Lihua Zhang ,  Boqiu Chen ,  Di Zhou ,  Shuangming Ye ,  Chiyu Ding ,  Hongping Lv ,  Bin Shao

    IPC: C07C35/21

    CPC classification number: C07C403/24 ,  A23L5/44 ,  A23L33/10 ,  C07C2601/16 ,  C09B61/00 ,  C09B67/0025 ,  C09B67/0096

    Abstract: This invention has disclosed a method for preparation of food-grade zeaxanthin through chemical isomerizaton reaction from lutein. The technical issues to be solved in this invention are quite low product yield obtained with existing methods, need of purification treatment process, and inadaptability to industrialized production. The technical schemes of this invention are: a. Mix xanthophyll crystal or its fatty acid ester with food-grade glycol or propylene glycol, for full dissolution under 60-90° C. temperature. Add organic alkali into the mixed liquor acquired from step 1, for isomerization reaction to take place under inertial environment. c. Dilute the reaction solution gained from step b with the mixed solution of deionized water and ethanol, and separate the obtained crystal with conventional separating method. d. Vacuum dries the acquired crystal from step c, to get the zeaxanthin crystal. Glycol or propylene glycol is used in this invention for isomerization reaction under inertial environment after it has fully dissolved raw material under proper temperature. The product yield is reachable to more than 60%, very adaptable to industrialized product, without the need for further purification treatment.

    Abstract translation: 本发明公开了通过叶黄素化学异构化反应制备食品级玉米黄质的方法。 本发明要解决的技术问题是用现有方法获得的产品产率相当低，需要净化处理工艺，以及对工业化生产的适应性。 本发明的技术方案是：a。 将叶黄素晶体或其脂肪酸酯与食品级二醇或丙二醇混合，在60-90℃的温度下完全溶解。 将有机碱添加到从步骤1获得的混合液中，以在惯性环境下进行异构化反应。 C。 用去离子水和乙醇的混合溶液稀释从步骤b获得的反应溶液，并用常规分离方法分离得到的晶体。 d。 真空干燥步骤c获得的晶体，得到玉米黄质晶体。 乙二醇或丙二醇在本发明中在适当温度下完全溶解原料之后，在惯性环境下用于异构化反应。 产品产量可达60％以上，非常适用于工业化产品，无需进一步净化处理。

    Aryl substituted pyridines and the use thereof
    35.
    发明申请
    Aryl substituted pyridines and the use thereof 有权
    芳基取代的吡啶及其用途

    公开(公告)号：US20070010554A1

    公开(公告)日：2007-01-11

    申请号：US11518448

    申请日：2006-09-11

    Applicant: Bin Shao ,  R. Goehring ,  Samuel Victory

    Inventor： Bin Shao ,  R. Goehring ,  Samuel Victory

    IPC: A61K31/4545 ,  A61K31/455 ,  C07D403/02

    CPC classification number: C07D213/81 ,  C07D213/82 ,  Y10T436/145555

    Abstract: This invention relates aryl substituted pyridines of Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein Ar and R1—R4 are set in the specification. The invention is also directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.

    Abstract translation: 本发明涉及式I的芳基取代的吡啶：或其药学上可接受的盐，前药或溶剂化物，其中Ar和R 1 -R 4定义在说明书中。 本发明还涉及式I化合物用于治疗全身和局部缺血后的神经元损伤，用于治疗或预防神经变性疾病如肌萎缩性侧索硬化（ALS）以及治疗，预防或改善的用途 作为抗惊厥剂，作为抗惊厥剂，作为抗躁狂抑制剂，作为局部麻醉剂，作为抗心律失常药物和用于治疗或预防糖尿病性神经病变。

    Aryl substituted pyridines and the use thereof
    36.
    发明授权
    Aryl substituted pyridines and the use thereof 有权
    芳基取代的吡啶及其用途

    公开(公告)号：US07105549B2

    公开(公告)日：2006-09-12

    申请号：US10235673

    申请日：2002-09-06

    Applicant: Bin Shao ,  R. Richard Goehring ,  Samuel F Victory ,  Qun Sun

    Inventor： Bin Shao ,  R. Richard Goehring ,  Samuel F Victory ,  Qun Sun

    IPC: A61K31/443 ,  A61K31/4439 ,  A61K31/451 ,  C07D213/60 ,  C07D401/04 ,  C07D405/04 ,  C07D413/04

    CPC classification number: C07D213/81 ,  C07D213/82 ,  Y10T436/145555

    Abstract: This invention relates aryl substituted pyridines of Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein Ar and R1–R4 are set in the specification. The invention is also directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.

    Abstract translation: 本发明涉及式I的芳基取代的吡啶：或其药学上可接受的盐，前药或溶剂化物，其中Ar和R 1 -R 4定义在说明书中。 本发明还涉及式I化合物用于治疗全身和局部缺血后的神经元损伤，用于治疗或预防神经变性疾病如肌萎缩性侧索硬化（ALS）以及治疗，预防或改善的用途 作为抗惊厥剂，作为抗惊厥剂，作为抗躁狂抑制剂，作为局部麻醉剂，作为抗心律失常药物和用于治疗或预防糖尿病性神经病变。

    ENERGY HARVESTER OPEN-CIRCUIT VOLTAGE SENSING FOR MPPT
    38.
    发明申请
    ENERGY HARVESTER OPEN-CIRCUIT VOLTAGE SENSING FOR MPPT 有权

    公开(公告)号：US20170117818A1

    公开(公告)日：2017-04-27

    申请号：US14939267

    申请日：2015-11-12

    Applicant: Bin Shao

    Inventor： Bin Shao

    IPC: H02M7/06

    CPC classification number: H02M7/066 ,  G01R19/00 ,  H02J7/00 ,  H02J7/0052 ,  H02J2007/0059

    Abstract: Apparatus and techniques described herein can include using an electronic circuit comprising a rectifier circuit, an open-circuit voltage (OCV) sampling circuit coupled to the output of the rectifier circuit, and a regulator circuit coupled to the output of the rectifier circuit. In an example, an isolation switch can be located between the regulator circuit and the rectifier circuit, the isolation switch configured to isolate the regulator circuit from the rectifier circuit for sampling of the open-circuit voltage by the open-circuit voltage sampling circuit. In another example, a buffer circuit can be used, such as placed in-line with a divider circuit between a divider circuit and an open-circuit voltage sampling capacitor. In this manner, the buffer circuit can provide a low output impedance, isolating the voltage sampling capacitor from the divider circuit.

    VOLTAGE DETECTION FOR LOW-POWER DEVICES
    40.
    发明申请
    VOLTAGE DETECTION FOR LOW-POWER DEVICES 审中-公开
    低功耗器件的电压检测

    公开(公告)号：US20150198635A1

    公开(公告)日：2015-07-16

    申请号：US14178931

    申请日：2014-02-12

    Applicant: Bin Shao ,  Yanfeng Lu

    Inventor： Bin Shao ,  Yanfeng Lu

    IPC: G01R19/00 ,  G01R19/252

    CPC classification number: G01R19/0084 ,  H02M3/156 ,  H02M3/33507 ,  H02M2001/0025

    Abstract: A device to sense voltage is provided. The device includes a first circuit operatively coupled to one or more nodes. The first circuit senses an electrical characteristic of each of the one or more nodes. The first circuit generates an adjustment signal based on the electrical characteristic sensed at each of the one or more nodes. A second circuit operatively receives a first voltage and a second voltage, the second circuit being configured to generate a third voltage by scaling the second voltage. The second circuit generates a comparison signal based on a comparison of the first voltage and the third voltage.

    Abstract translation: 提供感测电压的装置。 该设备包括可操作地耦合到一个或多个节点的第一电路。 第一电路感测一个或多个节点中的每一个的电特性。 第一电路基于在一个或多个节点中的每一个处感测到的电特性产生调整信号。 第二电路可操作地接收第一电压和第二电压，第二电路被配置为通过缩放第二电压来产生第三电压。 第二电路基于第一电压和第三电压的比较产生比较信号。

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