摘要:
A cyclized peptide designated BMP Binding Peptide (BBP) is a synthetic peptide that avidly binds rhBMP-2, as do endogenous forms of BBP, and sequence conservation between species results in a variety of useful BBP compositions. BBP increases the over-all osteogenic activity of rhBMP-2, increases the rate at which rhBMP-2 induces bone formation, and BBP induces calcification alone. Compositions and substrates including BBP, and methods of using BBP are useful in therapeutic, diagnostic and clinical applications requiring calcification and osteogenesis.
摘要:
A system for stabilizing a superior vertebra relative to an inferior vertebra includes a plate having a first surface for mating with the superior and inferior vertebra and a second surface opposite the first surface. The plate has a first hole configured for overlying the superior vertebra and a second hole configured for overlying the inferior vertebra. An alignment instrument has a leading portion and a trailing portion. The leading portion has a securing mechanism configured for removable attachment to a fastening mechanism of the plate. The alignment instrument also includes an alignment prong extending past the first surface of the plate when the plate is attached to the fastening mechanism. The alignment prong provides tactile information to the trailing portion of the alignment instrument for use in positioning the plate with respect to the superior and inferior vertebra.
摘要:
Computer-implemented methods, computer-readable media, and an application system are disclosed for creating and deploying metadata-generated applications. Access is provided to one or more type libraries that each include one or more defined object types configurable for use in generating the application. The defined object types include data structure types, rule types, and data types. Input is elicited from a user regarding desired content and function of the application. Based on the user input, metadata is generated to adapt the defined object types to generate the application. Metadata is generated to adapt the defined data structure types to create one or more application databases, to adapt the defined rule types to create one or more application behaviors, and to adapt the defined data types to create one or more application data types.
摘要:
A system and method for data communication connecting on-line networks with on-line and off-line computers. The present system provides for broadcast of up to the minute notification centric information thereby providing an instant call to action for users who are provided with the ability to instantaneously retrieve further detailed information. The notification centric portions of information is wirelessly broadcast to wireless receiving devices which are attached to computing devices. Upon receipt of the information at the personal computer, the user is notified through different multimedia alerts that there is an incoming message. Wirelessly broadcasted URL's, associated with the data, are embedded in data packets and provide an automated wired or wireless connection back to the information source for obtaining detailed data.
摘要:
Embodiments of the invention relate to a method and apparatus for coating a medical device. In one embodiment, the method for preparing a substantially uniform coated medical device includes (1) preparing a coating solution comprising a solvent, a therapeutic agent, and an additive; (2) loading a metering dispenser with the coating solution; (3) rotating the medical device about the longitudinal axis of the device and/or moving the medical device along the longitudinal or transverse axis of the device; (4) dispensing the coating solution from the metering dispenser onto a surface of the medical device and flowing the coating solution on the surface of the medical device while the medical device is rotating and/or linearly moving; and (5) evaporating the solvent, forming a substantially uniform coating layer on the medical device.
摘要:
A method of manufacturing an integrated lead head suspension flexure of the type having conductors on a spring metal layer capable of being etched by a first etching process. The method includes forming a patterned layer having gaps one or more flying lead regions of dielectric material on a major surface of the spring metal layer and forming one or more conductive leads on the flexure, including onto the dielectric material and over exposed spring metal at the gap at each flying lead region. At least the flying lead portion of the conductive lead is formed from conductive material resistant to the first etching process. The method also includes etching a flying lead region of the spring metal layer to remove a portion of the spring metal layer in the flying lead region and expose the flying lead portions of the conductive lead.
摘要:
The present invention relates generally to sets of digital antibodies directed against short epitopes, and use thereof in methods for protein analysis.
摘要:
A file management system for utilizing both NOR and NAND flash memory technology in a system is disclosed. Control structures are stored within NOR flash memory blocks. Data structures are stored within NAND flash memory blocks.
摘要:
A system and method for data communication connecting on-line networks with on-line and off-line computers. The present system provides for broadcast of up to the minute notification centric information thereby providing an instant call to action for users who are provided with the ability to instantaneously retrieve further detailed information. The notification centric portions of information is wirelessly broadcast to wireless receiving devices which are attached to computing devices. Upon receipt of the information at the personal computer, the user is notified through different multimedia alerts that there is an incoming message. Wirelessly broadcasted URL's, associated with the data, are embedded in data packets and provide an automated wired or wireless connection back to the information source for obtaining detailed data.
摘要:
An adjunct network device includes several ports, an uplink interface, and an adjunct forwarding engine coupled to the ports and the uplink interface. A first port is configured to receive a packet, which includes a destination address. The adjunct forwarding engine is configured to send the packet to the uplink interface if the destination address is not associated with any of the ports. The packet is sent to one of the ports if the destination address is associated with the one of the ports.