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    NUCLEIC ACID DETECTION METHOD AND NUCLEIC ACID DETECTION KIT
    31.
    发明申请
    NUCLEIC ACID DETECTION METHOD AND NUCLEIC ACID DETECTION KIT 有权
    核酸检测方法和核酸检测试剂盒

    公开(公告)号：US20100330564A1

    公开(公告)日：2010-12-30

    申请号：US12677189

    申请日：2008-08-27

    申请人： Jun Tomono

    发明人： Jun Tomono

    IPC分类号： C12Q1/68

    CPC分类号： G01N33/5308 ,  C12Q1/6844 ,  G01N33/566 ,  Y02A50/59 ,  C12Q2565/113 ,  C12Q2563/107 ,  C12Q2565/625 ,  C12Q2565/137 ,  C12Q2565/531

    摘要： In the present invention, an amplified DNA fragment having a first substance binding site to which a first substance is specifically bindable is prepared, which amplified DNA fragment amplified by a nucleic acid amplification method. The amplified DNA fragment is concentrated by binding the amplified DNA fragment to the first substance. The concentration makes it possible to detect the DNA highly sensitively. Therefore, with the arrangement, it is possible to detect the amplified DNA fragment amplified by the nucleic acid amplification method, easily and highly accurately without requiring any special device.

    摘要翻译： 在本发明中，制备具有第一物质特异性结合的第一物质结合位点的扩增DNA片段，扩增通过核酸扩增法扩增的DNA片段。 通过将扩增的DNA片段与第一物质结合来浓缩扩增的DNA片段。 该浓度使得可以高度灵敏地检测DNA。 因此，通过该配置，可以容易且高精度地检测通过核酸扩增方法扩增的扩增的DNA片段，而不需要任何特殊的装置。

    AGARASE AND GENE THEREOF
    33.
    发明申请
    AGARASE AND GENE THEREOF 失效
    其基因及其基因

    公开(公告)号：US20080096249A1

    公开(公告)日：2008-04-24

    申请号：US11948650

    申请日：2007-11-30

    申请人： Jun TOMONO ,  Hiroaki Sagawa ,  Ikunoshin Kato

    发明人： Jun TOMONO ,  Hiroaki Sagawa ,  Ikunoshin Kato

    IPC分类号： C12N9/00 ,  C12N15/00 ,  C12N15/11 ,  C12P21/04 ,  C12N5/06

    CPC分类号： C12Y302/01081 ,  C12N9/2468

    摘要： Production of efficiently producing agaro-oligosaccharide; a polypeptide having an agarase activity which is usable in, for example, efficiently extracting a substance such as a nucleic acid from an agarose gel; the amino acid sequence of the polypeptide; a gene encoding the polypeptide; a process for producing the polypeptide; a process for producing agaro-oligosaccharide; and a process for extracting a substance such as a nucleic acid from an agarose gel.

    摘要翻译： 高效生产琼脂寡糖的生产; 具有琼脂糖酶活性的多肽，其可用于例如从琼脂糖凝胶中有效地提取诸如核酸的物质; 多肽的氨基酸序列; 编码该多肽的基因; 一种生产该多肽的方法; 制备琼脂寡糖的方法; 以及从琼脂糖凝胶中提取核酸等物质的方法。

    Ice crystallization inhibitor derived from basidiomycete
    38.
    发明授权
    Ice crystallization inhibitor derived from basidiomycete 有权
    来自担子菌的冰结晶抑制剂

    公开(公告)号：US08734672B2

    公开(公告)日：2014-05-27

    申请号：US13818637

    申请日：2011-08-11

    申请人： Hidehisa Kawahara ,  Yoshihide Koide ,  Naoki Arai ,  Jun Tomono

    发明人： Hidehisa Kawahara ,  Yoshihide Koide ,  Naoki Arai ,  Jun Tomono

    IPC分类号： C09K3/18 ,  C08K3/00 ,  A23L1/03 ,  A23L1/30 ,  A01N1/02 ,  A61K8/73 ,  A61K8/99

    CPC分类号： C09K5/20 ,  A01N1/0221 ,  A23L3/3463 ,  A23L3/3472 ,  A23L5/00 ,  A23L15/20 ,  A23L15/30 ,  A23L17/00 ,  A23L31/00 ,  A61K8/73 ,  A61Q19/00 ,  C07K14/415 ,  C07K16/44

    摘要： The objective to be solved by the present invention is to provide an ice-crystallization inhibitor which has a practicable and excellent ice-crystallization inhibiting property and which can be efficiently and stably produced in a safe process suitable for food production. Also, the objective of the present invention is to provide an antibody which specifically reacts with the ice-crystallization inhibitor, and a composition, a food, a biological sample protectant and a cosmetic which contain the ice-crystallization inhibitor. Furthermore, the objective of the present invention is to provide a polysaccharide which is derived from a basidiomycete and which is used for inhibiting ice-crystallization of a liquid containing water, and a method for inhibiting ice-crystallization of a liquid containing water. The ice-crystallization inhibitor according to the present invention is characterized in being a polysaccharide derived from a basidiomycete.

    摘要翻译： 本发明要解决的目的是提供一种冰结晶抑制剂，其具有可行且优异的结晶结晶抑制性能，并且可以在适于食品生产的安全工艺中有效且稳定地生产。 此外，本发明的目的是提供与冰结晶抑制剂特异性反应的抗体，以及含有冰结晶抑制剂的组合物，食品，生物样品保护剂和化妆品。 此外，本发明的目的是提供一种源自担子菌的多糖，其用于抑制含水液体的冰结晶，以及抑制含有水的液体的冰结晶的方法。 根据本发明的结冰抑制剂的特征在于来自担子菌的多糖。

    Method for detecting nucleic acid, and device or kit
    39.
    发明授权
    Method for detecting nucleic acid, and device or kit 有权
    检测核酸的方法，以及装置或试剂盒

    公开(公告)号：US08546131B2

    公开(公告)日：2013-10-01

    申请号：US12726680

    申请日：2010-03-18

    申请人： Shigehiko Miyamoto ,  Tomohisa Kato ,  Koji Takahashi ,  Jun Tomono

    发明人： Shigehiko Miyamoto ,  Tomohisa Kato ,  Koji Takahashi ,  Jun Tomono

    IPC分类号： C12M1/34 ,  C12M3/00 ,  G01N15/06 ,  C07H21/02 ,  C07H21/04

    CPC分类号： G01N21/78 ,  C12Q1/6816 ,  G01N33/52 ,  G01N33/5308 ,  C12Q2563/173 ,  C12Q2537/101 ,  C12Q2563/137

    摘要： A method and a device or kit for detecting a nucleic acid, which enable simple and precise visual detection of a nucleic acid amplified by an nucleic acid amplification method, without necessity of special devices are provided. The method for detecting a nucleic acid in a sample comprises: contacting a sample with a dye to react with each other; and observing a substance produced by the reaction with visible light, and evaluating the presence or absence of a nucleic acid by eye. The device or kit for detecting a nucleic acid in a sample comprises: a carrier that holds a dye which can bind to a nucleic acid; a path for passing a sample through the carrier; and an evaluation part for observing a substance produced by the reaction between the sample and the dye with visible light, and evaluating the presence or absence of a nucleic acid by eye.

    摘要翻译： 提供了用于检测核酸的方法和装置或试剂盒，其能够简单且精确地目视检测通过核酸扩增方法扩增的核酸，而不需要特殊的装置。 用于检测样品中核酸的方法包括：使样品与染料接触以进行反应; 并观察通过可见光反应产生的物质，并通过眼睛评估核酸的存在或不存在。 用于检测样品中的核酸的装置或试剂盒包括：载持可以结合核酸的染料的载体; 将样品通过载体的路径; 以及用于用可见光观察由样品和染料之间的反应产生的物质的评估部分，并且通过眼睛评估核酸的存在或不存在。

    Fibroblast Activator, Collagen Production Promoter, Collagen Contraction Promoter, Hyaluronic Acid Production Promoter, ATP Production Promoter, Melanin Formation Inhibitor, and Agent for External Application to the Skin
    40.
    发明申请
    Fibroblast Activator, Collagen Production Promoter, Collagen Contraction Promoter, Hyaluronic Acid Production Promoter, ATP Production Promoter, Melanin Formation Inhibitor, and Agent for External Application to the Skin 审中-公开
    成纤维细胞激活剂，胶原生成促进剂，胶原收缩启动子，透明质酸生产促进剂，ATP生产促进剂，黑色素形成抑制剂和外用于皮肤的药剂

    公开(公告)号：US20090253794A1

    公开(公告)日：2009-10-08

    申请号：US11989194

    申请日：2006-07-21

    申请人： Jun Tomono ,  Takahisa Nakai ,  Toshihide Fujii

    发明人： Jun Tomono ,  Takahisa Nakai ,  Toshihide Fujii

    IPC分类号： A61K31/195

    CPC分类号： A61Q19/08 ,  A61K8/44 ,  A61K31/195 ,  A61Q19/02

    摘要： The present invention is a fibroblast activator, collagen production promoter, collagen contraction promoter, hyaluronic acid production promoter, ATP production promoter or melanin formation suppressor, which contains, as an active ingredient, at least one kind of compound selected from the group consisting of conagenin, a conagenin derivative, and a pharmaceutically acceptable salt thereof, as well as a composition (skin external preparation, cosmetic, pharmaceutical product or food, which is a composition for the improvement of wrinkles or a whitening composition) containing such activator, promoter or melanin formation suppressor.According to the present invention, a safe skin external preparation, cosmetic (cosmetic composition), pharmaceutical product or food, which shows a high wrinkle improving effect, can be provided, and a safe skin external preparation, cosmetic (cosmetic composition), pharmaceutical product or food, which shows a high whitening effect can be provided.

    摘要翻译： 本发明是一种成纤维细胞激活剂，胶原产生促进剂，胶原蛋白收缩促进剂，透明质酸产生促进剂，ATP生产促进剂或黑色素形成抑制剂，其含有至少一种选自下列基团的化合物作为活性成分： ，配子衍生物及其药学上可接受的盐，以及含有这种活化剂，促进剂或黑色素的组合物（皮肤外用制剂，化妆品，药​​物产品或食品，其是用于改善皱纹或美白组合物的组合物） 形成抑制器。 根据本发明，可以提供显示出高皱纹改善效果的安全皮肤外用剂，化妆品（化妆品组合物），药品或食品，以及安全的皮肤外用剂，化妆品（化妆品组合物），药品 或食物，其可以提供高的美白效果。