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公开(公告)号:US09675484B2
公开(公告)日:2017-06-13
申请号:US15177219
申请日:2016-06-08
Applicant: Abbott Cardiovascular Systems Inc.
Inventor: Stephen D. Pacetti
IPC: A61F2/958 , B21D39/04 , A61F2/06 , B05C11/00 , A61F2/07 , A61F2/82 , A61L31/02 , A61L31/04 , A61L31/16 , A61F2/95
CPC classification number: A61F2/958 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2002/9522 , A61F2240/001 , A61L31/022 , A61L31/048 , A61L31/16 , A61L2300/416 , A61L2420/06 , B05C11/00 , B21D39/048 , Y10T29/49863 , Y10T29/49865 , Y10T29/49925 , Y10T29/49927 , Y10T29/53996
Abstract: A method for crimping a stent with a PC polymer coating in a humid environment is disclosed.
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32.
公开(公告)号:US20170112645A1
公开(公告)日:2017-04-27
申请号:US15398425
申请日:2017-01-04
Applicant: Abbott Cardiovascular Systems Inc.
Inventor: Stephen D. Pacetti , Joel Harrington
IPC: A61F2/915 , B29C35/08 , B23K26/402
CPC classification number: A61F2/915 , A61F2/91 , A61F2002/91558 , A61F2002/91583 , A61F2240/001 , B23K26/38 , B23K26/402 , B23K2103/42 , B23K2103/50 , B29C35/0805 , B29C2035/0838 , B29K2067/00 , B29K2105/005 , B29K2105/258 , B29K2995/006 , B29L2031/7532
Abstract: A method of laser machining a polymer construct to form a stent that includes a bioresorbable polymer and an absorber that increases absorption of laser energy during laser machining. The laser cuts the tubing at least in part by a multiphoton absorption mechanism and the polymer and absorber have a very low absorbance or are transparent to light at the laser wavelength.
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公开(公告)号:US09468707B2
公开(公告)日:2016-10-18
申请号:US14752637
申请日:2015-06-26
Applicant: Abbott Cardiovascular Systems Inc.
Inventor: Stephen D. Pacetti , O. Mikael Trollsas
IPC: A61F2/00 , A61F13/00 , A61K38/00 , A61F2/04 , A61L31/10 , A61L29/04 , A61L29/16 , A61L31/04 , A61L31/16 , A61K31/436 , A61L31/06 , C08G81/00
CPC classification number: A61L31/10 , A61K31/436 , A61L29/041 , A61L29/16 , A61L31/048 , A61L31/06 , A61L31/16 , A61L2300/606 , A61L2420/00 , C08G81/00
Abstract: The present invention is directed to polymeric materials made of biodegradable, bioabsorbable triblock copolymers and implantable devices (e.g., drug-delivery stents) containing such polymeric materials. The polymeric materials may also contain at least one therapeutic substance. The polymeric materials are formulated so as to improve the mechanical and adhesion properties, degradation, biocompatibility and drug permeability of such materials and, thus, implantable devices formed of such materials.
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公开(公告)号:US09421168B2
公开(公告)日:2016-08-23
申请号:US14221193
申请日:2014-03-20
Applicant: Abbott Cardiovascular Systems Inc.
Inventor: Wouter E. Roorda , Stephen D. Pacetti
IPC: A61K9/14 , A61K38/18 , A61K31/727 , A61K31/573 , A61K9/16 , A61K47/26 , A61K47/36 , A61K48/00
CPC classification number: A61K9/14 , A61K9/1617 , A61K9/1647 , A61K9/1658 , A61K9/1694 , A61K31/573 , A61K31/727 , A61K38/1825 , A61K47/26 , A61K47/36 , A61K48/00
Abstract: Compositions and methods of using the compositions are provided for forming an embolus within a region of an anatomical lumen for a transitory period in order to achieve a therapeutic effect.
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公开(公告)号:US09414942B2
公开(公告)日:2016-08-16
申请号:US14958060
申请日:2015-12-03
Applicant: Abbott Cardiovascular Systems Inc.
Inventor: Stephen D. Pacetti
CPC classification number: A61F2/915 , A61F2/86 , A61F2/88 , A61F2240/002 , A61F2250/0068 , A61F2250/0069 , B65B3/003 , B65B31/04
Abstract: An apparatus for loading material into a stent strut can comprise a chamber capable of maintaining an internal pressure below pressure external to the chamber. The chamber carries within it the stent and the material to be loaded into a lumen within the stent strut. Pressure within the chamber is decreased. The decreased pressure can draw the material into lumen. The decreased pressure can draw air out of the lumen so that, after a subsequent increase in pressure in the chamber, the material is drawn into the lumen.
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公开(公告)号:US20160228270A1
公开(公告)日:2016-08-11
申请号:US15132973
申请日:2016-04-19
Applicant: Abbott Cardiovascular Systems Inc.
Inventor: Stephen D. Pacetti
CPC classification number: A61F2/90 , A61F2/844 , A61F2/89 , A61F2/915 , A61F2230/0069 , A61F2250/0071 , A61F2250/0096 , A61F2250/0098 , A61L31/18
Abstract: An implantable sent comprises a radiopaque marker that provides a structural connection between two parts made of a polymer substrate material. The two parts can be one bending element of one radially expandable ring and another bending element of an adjacent expandable ring. The two parts can be two bending elements of the same radially expandable ring. The radiopaque marker can be in the form of an entire radially expandable ring.
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公开(公告)号:US09375334B2
公开(公告)日:2016-06-28
申请号:US14702525
申请日:2015-05-01
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor: Stephen D. Pacetti
CPC classification number: A61F2/958 , A61F2/06 , A61F2/07 , A61F2/82 , A61F2002/9522 , A61F2240/001 , A61L31/022 , A61L31/048 , A61L31/16 , A61L2300/416 , A61L2420/06 , B05C11/00 , B21D39/048 , Y10T29/49863 , Y10T29/49865 , Y10T29/49925 , Y10T29/49927 , Y10T29/53996
Abstract: A method for crimping a bioabsorbable stent in a humid environment is disclosed.
Abstract translation: 公开了一种在潮湿环境中卷曲生物可吸收支架的方法。
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38.
公开(公告)号:US20150374885A1
公开(公告)日:2015-12-31
申请号:US14752637
申请日:2015-06-26
Applicant: Abbott Cardiovascular Systems Inc.
Inventor: Stephen D. Pacetti , O. Mikael Trollsas
CPC classification number: A61L31/10 , A61K31/436 , A61L29/041 , A61L29/16 , A61L31/048 , A61L31/06 , A61L31/16 , A61L2300/606 , A61L2420/00 , C08G81/00
Abstract: The present invention is directed to polymeric materials made of biodegradable, bioabsorbable triblock copolymers and implantable devices (e.g., drug-delivery stents) containing such polymeric materials. The polymeric materials may also contain at least one therapeutic substance. The polymeric materials are formulated so as to improve the mechanical and adhesion properties, degradation, biocompatibility and drug permeability of such materials and, thus, implantable devices formed of such materials.
Abstract translation: 本发明涉及由可生物降解的,生物可吸收的三嵌段共聚物和含有这种聚合材料的可植入装置(例如药物递送支架)制成的聚合材料。 聚合物材料还可含有至少一种治疗物质。 配制聚合物材料以改善这些材料的机械和粘合性能,降解,生物相容性和药物渗透性,从而改善由这些材料形成的可植入装置。
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39.
公开(公告)号:US20150359647A1
公开(公告)日:2015-12-17
申请号:US14302295
申请日:2014-06-11
Applicant: Abbott Cardiovascular Systems Inc.
Inventor: Stephen D. Pacetti , Ni Ding
IPC: A61F2/90
Abstract: Methods of making polymeric devices, such as stents, using solvent based processes. More particularly, methods of making bioabsorbable stents.
Abstract translation: 使用基于溶剂的方法制造聚合物装置例如支架的方法。 更具体地,制备生物可吸收支架的方法。
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公开(公告)号:US20150196404A1
公开(公告)日:2015-07-16
申请号:US14659276
申请日:2015-03-16
Applicant: Abbott Cardiovascular Systems Inc.
Inventor: Yung-Ming Chen , Jason Van Sciver , Syed F.A. Hossainy , Stephen D. Pacetti
IPC: A61F2/82
CPC classification number: B29C65/76 , A61F2/82 , A61F2/86 , A61F2/91 , A61F2210/0004 , A61F2210/0076 , A61F2240/001 , A61F2250/0067 , A61F2310/00389 , A61L31/14 , A61L31/148 , A61L2420/02 , B05D1/38 , B05D3/0254 , B05D3/0473 , B29C65/10 , B29K2067/046 , B29K2105/258 , B29L2031/7534
Abstract: Various embodiments of methods for coating stents are described herein. Applying a composition including polymer component and solvent to a stent substrate followed by exposing the polymer component to a temperature equal to or greater than a Tg of the polymer component is disclosed. Repeating the applying and exposing one or more times to form a coating with the result that the solvent content of the coating after the final exposing step is at a level suitable for a finished stent is further disclosed.
Abstract translation: 本文描述了用于涂覆支架的方法的各种实施例。 公开了将包含聚合物组分和溶剂的组合物施用到支架基底,然后将聚合物组分暴露于等于或大于聚合物组分的Tg的温度。 重复施加和暴露一次或多次以形成涂层,结果是在最终曝光步骤之后涂层的溶剂含量处于适合成品支架的水平。
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