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    Rotatable dynamic seal and guide for a medical obstruction treatment device sub-assembly coupled to a drive motor unit
    33.
    发明授权
    Rotatable dynamic seal and guide for a medical obstruction treatment device sub-assembly coupled to a drive motor unit 有权
    用于医疗阻塞治疗装置子组件的可旋转的动态密封和引导件，其联接到驱动马达单元

    公开(公告)号：US6022363A

    公开(公告)日：2000-02-08

    申请号：US217786

    申请日：1998-12-21

    申请人： Blair D. Walker ,  Scott L. Pool

    发明人： Blair D. Walker ,  Scott L. Pool

    IPC分类号： A61B17/00 ,  A61B17/22 ,  A61B17/32

    CPC分类号： A61B17/320758 ,  A61B2017/0046 ,  A61B2017/320012

    摘要： A miniaturized obstruction treatment device, e.g., a brush, particularly adapted for medical use formed at the distal end of an elongated brush drive shaft having a hollow lumen formed therein for introduction over a guidewire. The brush drive shaft is enclosed in the lumen of an brush delivery catheter, and the brush bristles of the distal brush are adapted to be garaged in a distal end section of the brush delivery catheter lumen. A Y-connector and an brush sub-assembly connector are attached to the proximal end of the brush delivery catheter and form an brush sub-assembly with the brush drive shaft and brush. The Y-connector allows infusion of thrombolytic agents into the brush delivery catheter lumen for emission at the distal end opening thereof adjacent the brush. In use, the brush sub-assembly connector connects the brush sub-assembly with a drive motor unit connector of a drive motor unit. The drive motor unit receives the proximal end of the drive shaft and rotates it to rotate the brush bristles. The brush and brush drive shaft distal section are automatically extended out of the catheter lumen distal end opening when the sub-assembly connector and the drive motor unit connector positively lock together. Simultaneously, a drive hub of the brush drive shaft locks into a drive chuck of a drive motor unit to enable rotation of the drive shaft, and the proximal drive shaft end is seated in a dynamic seal that inhibits infiltration of blood and thrombolytic agent into the drive motor housing.

    摘要翻译： 一种小型化阻塞治疗装置，例如特别适用于医疗用途的刷子，其形成在细长刷驱动轴的远端，其具有形成在其中的中空腔，用于引导导丝。 电刷驱动轴被封闭在电刷输送导管的内腔中，并且远侧刷的刷毛适合于在刷递送导管管腔的远端部分中被储存。 Y型连接器和刷子子组件连接器附接到刷递送导管的近端并且与刷驱动轴和刷子形成刷子子组件。 Y型连接器允许将血栓溶解剂输注到刷递送导管管腔中，以在与刷子相邻的远端开口处发射。 在使用中，刷子组件连接器将刷子组件与驱动电动机单元的驱动电机单元连接器相连。 驱动马达单元接收驱动轴的近端并使其旋转以旋转刷毛。 当子组件连接器和驱动电机单元连接器积极地锁定在一起时，刷和驱动轴远端部分自动延伸出导管内腔远端开口。 同时，刷驱动轴的驱动轮毂锁定到驱动马达单元的驱动卡盘中，以使得驱动轴能够旋转，并且近侧驱动轴端部位于动态密封件中，该动态密封件阻止血液和溶栓剂渗透入 驱动电机外壳。

    Pleated Bag for Interventional Pullback Systems
    35.
    发明申请
    Pleated Bag for Interventional Pullback Systems 有权
    折叠袋用于介入回退系统

    公开(公告)号：US20120130250A1

    公开(公告)日：2012-05-24

    申请号：US13361674

    申请日：2012-01-30

    申请人： Timothy K. Glynn ,  Ernest W. Heflin ,  Norman H. Hossack ,  Julie A. Riolo ,  Blair D. Walker

    发明人： Timothy K. Glynn ,  Ernest W. Heflin ,  Norman H. Hossack ,  Julie A. Riolo ,  Blair D. Walker

    IPC分类号： A61B8/12

    CPC分类号： A61B19/081 ,  A61B8/12 ,  A61B8/4422 ,  A61B8/4461 ,  A61B8/4488 ,  A61B46/10

    摘要： The present invention provides for pleated bags used with interventional pullback systems, including imaging catheters such as IVUS catheters, as well as for use with other catheters. An exemplary pleated bag of the present invention may be an elongate, sterile bag, having a plurality of pleats near the distal end, and including an orifice proximal to the pleats designed to allow passage of a catheter into the bag. The present invention also provides for a system that includes a pullback device, catheter, and pleated bag. The present invention allows for improved imaging catheter procedures at reduced costs.

    摘要翻译： 本发明提供了与介入回拉系统一起使用的打褶袋，包括诸如IVUS导管的成像导管，以及用于其它导管。 本发明的示例性打褶袋可以是细长的无菌袋，其具有在远端附近的多个褶皱，并且包括靠近褶皱的孔，其被设计成允许导管通过袋中。 本发明还提供一种包括回拉装置，导管和打褶袋的系统。 本发明允许以降低的成本改进成像导管程序。

    Longitudinally extendable infusion device
    37.
    发明授权
    Longitudinally extendable infusion device 失效
    纵向延伸输液装置

    公开(公告)号：US5624396A

    公开(公告)日：1997-04-29

    申请号：US550160

    申请日：1995-10-30

    申请人： Thomas O. McNamara ,  Blair D. Walker

    发明人： Thomas O. McNamara ,  Blair D. Walker

    IPC分类号： A61M25/00 ,  A61B17/22 ,  A61M25/01 ,  A61M29/02 ,  A61M37/00 ,  A61M39/00 ,  A61M11/00

    CPC分类号： A61M29/02 ,  A61B17/22 ,  A61M25/09 ,  A61B2017/22084 ,  A61M2025/09083 ,  A61M2025/091 ,  A61M2025/109 ,  A61M2025/1093 ,  A61M25/0105

    摘要： A system for use in delivering a thrombolytic agent to a firm obstruction in a blood vessel by effecting longitudinal extension of the distal infusion segment of an infusion device through the obstruction as the obstruction is dissolved by the delivery of the thrombolytic agent. The infusion device is inserted into the lumen of an introducer to straighten the distal infusion segment and the assembly is advanced through a selected path in a patient's vascular system to the obstructed site. The distal infusion segment is advanced from a distal end opening of the introducer sheath lumen and assumes the pre-biased J-shaped bend configuration when positioned that tends to present the infusion port in a side wall toward the obstruction. A spring loaded assembly is coupled between the proximal ends of the infusion device and the introducer catheter that applies a force axially along the body of the infusion device against the resistance of the obstruction in contact with the distal infusion segment. As the dissolving agent is delivered and the obstruction dissolves, the distal infusion segment tunnels through the soft obstruction under the influence of the applied axial force.

    摘要翻译： 一种用于将血栓溶解剂输送到血管中的坚固阻塞物的系统，其通过阻塞物通过溶栓剂的输送溶解而通过阻塞物进行输注装置的远端输注段的纵向延伸。 将输注装置插入导引器的内腔以矫正远端输注部分，并且组件通过患者血管系统中的选定路径前进到阻塞部位。 远端输注部分从引导器套管内腔的远端开口前进，并且当定位时呈现预偏压的J形弯曲构造，其倾向于将侧壁中的输注端口呈向阻塞。 弹簧加载的组件联接在输注装置的近端和引导器导管之间，该引导器导管克服抗与远端输注段接触的阻力沿着输注装置的主体轴向地施加力。 当溶解剂被输送并且阻塞物溶解时，远端输注部分在施加的轴向力的影响下穿过软质阻塞物。

    Open core heat exchange catheter, system and method
    38.
    发明授权
    Open core heat exchange catheter, system and method 有权
    开放式核心换热导管，系统及方法

    公开(公告)号：US06709448B2

    公开(公告)日：2004-03-23

    申请号：US10120587

    申请日：2002-04-11

    申请人： Blair D. Walker ,  Wayne A. Noda

    发明人： Blair D. Walker ,  Wayne A. Noda

    IPC分类号： A61F700

    CPC分类号： A61F7/12 ,  A61F2007/126

    摘要： A heat exchange catheter having an open core includes a catheter body for use in the central vasculature of a patient. The catheter body having a balloon with at least one heat exchange lumen for exchanging heat with flowing blood. The balloon inflates from a collapsed configuration to an inflated configuration. In the inflated configuration the balloon facilitates the flow of heat exchange fluid through the heat exchange lumen, which wraps in a helical pattern to define the open core and to enable blood to flow through the open core during use of the catheter. The open core defines an inside and an outside, the heat exchange lumen has non-contiguous helical winds to allow flowing blood to mix between the inside of the open core and the outside of the open core.

    摘要翻译： 具有开放芯的热交换导管包括用于患者中央脉管系统的导管体。 所述导管体具有气囊，所述气囊具有至少一个热交换腔，用于与流动的血液进行热交换。 气球从折叠构型膨胀到膨胀构型。 在膨胀构型中，球囊有助于热交换流体流过热交换腔，该热交换腔以螺旋形图案包裹以限定开放的芯并且在使用导管期间使血液能够流过开放的芯。 打开的芯限定内部和外部，热交换腔具有不连续的螺旋风，以允许流动的血液在开放的芯的内部和开放的芯的外部之间混合。

    Heat exchange catheter having helically wound reinforcement
    39.
    发明授权
    Heat exchange catheter having helically wound reinforcement 有权

    公开(公告)号：US06641603B2

    公开(公告)日：2003-11-04

    申请号：US10120590

    申请日：2002-04-11

    申请人： Blair D. Walker ,  Nora T. Pham

    发明人： Blair D. Walker ,  Nora T. Pham

    IPC分类号： A61F700

    CPC分类号： A61F7/12 ,  A61F2007/126

    摘要： A intravascular heat exchange catheter includes a catheter body having a proximal end connectable with a heat exchange fluid source and a distal end insertable into the vasculature of a patient to facilitate heat transfer with flowing blood. The core has at least one heat exchange fluid lumen for circulating heat exchange fluid within the catheter body. A heat exchanger, e.g. a balloon surrounds a portion of the proximal end of the catheter. The heat exchanger is in fluid communication with the heat exchange fluid lumen for enabling heat exchange fluid from the heat exchange fluid source to circulate through the core and the balloon. A wire, or similar retainer, wraps around the balloon to seal the balloon against the core, forming at least two heat exchange lumens between the balloon and the core.

    Exchangeable integrated-wire balloon catheter
    40.
    发明授权
    Exchangeable integrated-wire balloon catheter 失效
    可换式集成丝球囊导管

    公开(公告)号：US5364354A

    公开(公告)日：1994-11-15

    申请号：US970581

    申请日：1992-10-22

    申请人： Blair D. Walker ,  Sheryl W. Higgins

    发明人： Blair D. Walker ,  Sheryl W. Higgins

    IPC分类号： A61M25/00 ,  A61F2/958 ,  A61L29/04 ,  A61M25/01 ,  A61M29/02 ,  A61M29/00

    CPC分类号： A61M25/104 ,  A61L29/04 ,  A61M25/09 ,  A61M25/10 ,  A61M2025/0047 ,  A61M2025/09008 ,  A61M2025/091 ,  A61M2025/1052 ,  A61M2025/1063 ,  A61M2025/1079 ,  A61M2025/1093 ,  A61M25/0075 ,  A61M25/1002

    摘要： A fully exchangeable integrated-wire dilation catheter for performing angioplasty is disclosed having a flexible small diameter guide wire provided with an enlarged diameter distal end portion and a flexible elongated tubular shaft with at least one dual function fluid conducting lumen adapted to receive the guide wire extending therethrough. The distal end of the tubular shaft is connected to the proximal end of an expandable balloon provided with a coaxially aligned distal orifice having means for releasably engaging the enlarged distal end portion of the guide wire in sealing relationship. In a preferred embodiment the sealing means is a flexible sleeve extending from the distal orifice of the expandable balloon and dimensioned to slidingly engage the correspondingly sized enlarged distal end portion of the guide wire. Associated procedures for utilizing the dilation catheter are also disclosed.

    摘要翻译： 公开了一种用于执行血管成形术的完全可交换的集成线膨胀导管，其具有柔性小直径导丝，其具有扩大的直径远端部分和柔性细长管状轴，该至少一个双功能流体传导腔适于接收延伸的导丝 通过。 管状轴的远端连接到设置有同轴对准的远端口的可膨胀气囊的近端，该远端孔具有用于以密封关系可释放地接合导丝的扩大的远端部分的装置。 在优选实施例中，密封装置是从可膨胀气囊的远端孔延伸的柔性套管，其尺寸被设计成滑动地接合导丝的相应尺寸的扩大的远端部分。 还公开了利用扩张导管的相关程序。