公开(公告)号：US20100256764A1

公开(公告)日：2010-10-07

申请号：US12751944

申请日：2010-03-31

申请人： Yang-Hwei Tsuang ,  Chang Jung Chiang ,  Shan-Chang Chueh ,  Chun-Jen Liao ,  Chung-Nun Chen ,  Ya-Jen Yu

发明人： Yang-Hwei Tsuang ,  Chang Jung Chiang ,  Shan-Chang Chueh ,  Chun-Jen Liao ,  Chung-Nun Chen ,  Ya-Jen Yu

IPC分类号： A61F2/44

CPC分类号： A61F2/442 ,  A61F2/4611 ,  A61F2002/2835 ,  A61F2002/3052 ,  A61F2002/3055 ,  A61F2002/30579 ,  A61F2002/4475 ,  A61F2002/448 ,  A61F2002/4485 ,  A61F2002/4623 ,  A61F2002/4627 ,  A61F2002/4628 ,  A61F2002/4629 ,  A61F2220/0025 ,  A61F2310/00221 ,  A61F2310/00293 ,  A61F2310/00365 ,  A61F2310/00383

摘要： A spinal cage is provided to be implanted in an intervertebral disc space. The spinal cage includes a first segment and a second segment movably connected with each other. The first segment is slidable with respect to the second segment, so as to elongate the spinal cage from a retracted state to an extended state.

摘要翻译： 提供脊柱笼以植入椎间盘空间。 脊柱笼包括彼此可移动地连接的第一段和第二段。 第一段可相对于第二段滑动，从而将脊柱笼从缩回状态延伸至延伸状态。

公开(公告)号：US20090007937A1

公开(公告)日：2009-01-08

申请号：US12104685

申请日：2008-04-17

申请人： Chung-Nun Chen ,  Chun-Jen Liao ,  Chin-Yu Lin ,  Chin-Fu Chen ,  Yung-chih Wu

发明人： Chung-Nun Chen ,  Chun-Jen Liao ,  Chin-Yu Lin ,  Chin-Fu Chen ,  Yung-chih Wu

IPC分类号： B08B3/04

CPC分类号： B08B3/102 ,  B01L3/502 ,  B01L2300/045 ,  B01L2300/046 ,  B01L2300/0681 ,  B01L2300/0832 ,  B01L2400/0478 ,  C12M47/12

摘要： In a general aspect, an apparatus for washing biological material is provided which includes an outer sleeve, and an inner sleeve disposed within the outer sleeve. The outer sleeve has an open end for receiving the biological material, and an opposed closed end. The inner sleeve is detachably and slidably positioned within the outer sleeve, and includes a first port for receiving and dispensing washing liquid, a second port defining a liquid flow path between an interior of the inner sleeve and an interior of the outer sleeve, and a filter disposed in the second port. The filter allows passage of washing liquid but not passage of the biological material therethrough. A chamber, formed between the filter and the closed end of the outer sleeve, is configured to permit flow of washing liquid via the filter while retaining the biological material therein.

摘要翻译： 在一般方面，提供了一种用于洗涤生物材料的装置，其包括外套筒和设置在外套筒内的内套筒。 外套筒具有用于接收生物材料的开口端和相对的封闭端。 所述内套筒可拆卸地且可滑动地定位在所述外套筒内，并且包括用于接收和分配洗涤液体的第一端口，限定所述内套筒的内部和所述外套筒的内部之间的液体流路的第二端口，以及 过滤器设置在第二端口中。 过滤器允许洗涤液体通过，但不允许生物材料通过。 形成在过滤器和外套管的封闭端之间的室被构造成允许经由过滤器流动清洗液体，同时将生物材料保持在其中。

公开(公告)号：US20080026455A1

公开(公告)日：2008-01-31

申请号：US11808117

申请日：2007-06-06

申请人： Chun-Jen Liao ,  Yu-Ju Lin ,  Chin-Fu Chen ,  Ken-Yuan Chang ,  Shu-Fang Chiang

发明人： Chun-Jen Liao ,  Yu-Ju Lin ,  Chin-Fu Chen ,  Ken-Yuan Chang ,  Shu-Fang Chiang

IPC分类号： C12M3/00

CPC分类号： C12N5/0655 ,  C12N5/0062 ,  C12N2533/40

摘要： A porous chamber for tissue culture in vitro. The porous chamber includes a main body made of porous biologically absorbable polymer material, comprising an inner surface surrounding a hollow cavity, the hollow cavity having an aperture opened at an upper surface of the main body, wherein the aperture is communicated with outside of the main body for seeding tissue blocks in the hollow cavity, and an upper cover passing through the upper surface of the main body to seal the aperture to prevent the tissue blocks from outflowing.

摘要翻译： 用于组织培养的多孔室。 所述多孔室包括由多孔生物可吸收聚合物材料制成的主体，包括围绕中空腔的内表面，所述中空腔具有在所述主体的上表面处开口的孔，其中所述孔与所述主体的外部连通 在中空腔中播种组织块的主体，以及穿过主体的上表面的上盖，以密封孔以防止组织块流出。

公开(公告)号：US07151139B2

公开(公告)日：2006-12-19

申请号：US10123860

申请日：2002-04-16

申请人： Joerg C. Tiller ,  Chun-Jen Liao ,  Kim Lewis ,  Alexander M. Klibanov

发明人： Joerg C. Tiller ,  Chun-Jen Liao ,  Kim Lewis ,  Alexander M. Klibanov

IPC分类号： C08L67/02

CPC分类号： A61L27/50 ,  A01N43/40 ,  A61L27/34 ,  A01N25/34 ,  A01N25/10 ,  A01N2300/00 ,  C08L33/14

摘要： Bactericidal compositions are disclosed that comprise a polymeric compound immobilized on a material. Medical devices are also disclosed which comprise such a bactericidal composition. Methods are disclosed for covalently derivatizing the surfaces of common materials with an antibacterial polycation, e.g., poly(vinyl-N-pyridinium bromide); the first step of the methods involves coating the surface with a nanolayer of silica. Various commercial synthetic polymers derivatized in this manner are bactericidal, i.e., they kill on contact up to 99% of deposited Gram-positive and Gram-negative bacteria, whether deposited through air or water.

公开(公告)号：US20060223175A1

公开(公告)日：2006-10-05

申请号：US11176411

申请日：2005-07-07

申请人： Yu-Chen Hu ,  Huang-Chi Chen ,  Chun-Jen Liao

发明人： Yu-Chen Hu ,  Huang-Chi Chen ,  Chun-Jen Liao

IPC分类号： C12M3/00

CPC分类号： C12M35/04 ,  C12M41/12

摘要： A bioreactor for cultivating tissue cells comprises a vessel containing a gas phase and a liquid phase therein, at least a substrate on which the tissue cells are attached, and a movable shaft to which the substrate is fixed. The movable shaft carries the substrate into and out of the gas and liquid phases so as to apply shear stress to the tissue cells.

摘要翻译： 用于培养组织细胞的生物反应器包括其中包含气相和液相的容器，至少其上附着有组织细胞的基底和固定有基底的活动轴。 可移动轴将衬底进入和离开气相和液相，以向组织细胞施加剪切应力。

公开(公告)号：US06824716B2

公开(公告)日：2004-11-30

申请号：US10241440

申请日：2002-09-12

申请人： Chun-Jen Liao ,  Yu-Ju Lin ,  Chin-Fu Chen ,  Ken-Yuan Chang

发明人： Chun-Jen Liao ,  Yu-Ju Lin ,  Chin-Fu Chen ,  Ken-Yuan Chang

IPC分类号： B29C6720

CPC分类号： C08J9/26 ,  B29C67/202 ,  C08J2201/042 ,  C08J2201/044 ,  C08J2201/0464

摘要： A process for producing porous polymer material. The method combines a polymer and water-soluble granules to form a mixture. The mixture is placed into a mold; the surface of the polymer is dissolved to cause cohesion and form a polymer structure having water-soluble granules dispersed within, and water is introduced into the inner part of the polymer structure so that the polymer is solidified and water-soluble granules are washed out to obtain a porous polymer material. According to the invention, single or multiple layers of porous polymer material with different apertures, porosities, or made with different materials, are obtained by combining different polymer materials and water-soluble granules having different particle sizes in different weight ratios.

摘要翻译： 一种多孔聚合物材料的制造方法。 该方法结合聚合物和水溶性颗粒以形成混合物。 将混合物放入模具中; 溶解聚合物的表面以引起内聚，并形成分散在其中的水溶性颗粒的聚合物结构，并且将水引入聚合物结构的内部，使得聚合物固化并将水溶性颗粒冲洗至 获得多孔聚合物材料。 根据本发明，通过将不同聚合物材料和具有不同重量比的不同粒度的水溶性颗粒结合，获得具有不同孔径，孔隙率或不同材料制成的单层或多层多孔聚合物材料。

公开(公告)号：US08986394B2

公开(公告)日：2015-03-24

申请号：US13458903

申请日：2012-04-27

申请人： Chun-Jen Liao ,  Sheng-Hong Tseng ,  Huang-Chien Liang ,  Chun-Hung Chen ,  Yi-Chun Su

发明人： Chun-Jen Liao ,  Sheng-Hong Tseng ,  Huang-Chien Liang ,  Chun-Hung Chen ,  Yi-Chun Su

IPC分类号： A61F2/02 ,  A61F2/28 ,  A61L27/36 ,  A61B17/68 ,  A61F2/30

CPC分类号： A61F2/2875 ,  A61B17/688 ,  A61F2/2846 ,  A61F2/30907 ,  A61F2002/285 ,  A61F2002/30433 ,  A61F2002/30448 ,  A61F2002/30462 ,  A61F2220/0041 ,  A61F2220/005 ,  A61F2220/0075 ,  A61L27/3675

摘要： An artificial dura biomedical device and a brain surgery method utilizing the same are disclosed. The steps includes: fixing an artificial dura to a partial skull; and fixing the partial skull with the artificial dura to a cut hole of a whole skull. The artificial dura biomedical device includes an artificial dura and a connecting element. The connecting element fixes the partial skull with the artificial dura.

摘要翻译： 公开了一种人造硬脑膜生物医学装置和利用其的脑手术方法。 步骤包括：将人造硬膜固定在部分头骨上; 并将具有人造硬脑膜的部分头骨固定到整个头骨的切割孔。 人造硬脑膜生物医学装置包括人造硬膜和连接元件。 连接元件用人造硬脑膜固定部分头骨。

公开(公告)号：US08876841B2

公开(公告)日：2014-11-04

申请号：US12505722

申请日：2009-07-20

申请人： Yang-Hwei Tsuang ,  Huang-Chien Liang ,  Chun-Hung Chen ,  Chun-Jen Liao ,  Chang-Jung Chiang ,  Chih-Hong Yang

发明人： Yang-Hwei Tsuang ,  Huang-Chien Liang ,  Chun-Hung Chen ,  Chun-Jen Liao ,  Chang-Jung Chiang ,  Chih-Hong Yang

IPC分类号： A61B17/04 ,  A61B17/06 ,  A61B17/29

CPC分类号： A61B17/0469 ,  A61B17/0482 ,  A61B2017/0472 ,  A61B2017/06042 ,  A61B2017/2943

摘要： An apparatus for anulus fibrosus repair includes a shaft, a pair of curved suturing needles mounted in parallel on the shaft, and a rotational driving mechanism connected to the shaft, which is configured to rotate the shaft and the pair of needles about a rotation axis of the shaft. Each needle includes a substantially semi-annular body having a proximal end, a distal end, an inner periphery, and an outer periphery, and an arm extending radially inward from the proximal end, in which a concavity is formed in the body proximate to the distal end extending in a direction away from it. Also disclosed is a suturing technique associated with use of the repair apparatus.

摘要翻译： 用于纤维性纤维修复的装置包括轴，平行安装在轴上的一对弯曲缝合针和连接到所述轴的旋转驱动机构，所述旋转驱动机构被构造成使所述轴和所述一对针绕着 轴。 每个针包括具有近端，远端，内周边和外周边的基本上半环形的主体，以及从近端径向向内延伸的臂，其中凹部形成在主体中，靠近 远端在远离其的方向延伸。 还公开了与使用修复装置相关联的缝合技术。

公开(公告)号：US08778883B2

公开(公告)日：2014-07-15

申请号：US12618381

申请日：2009-11-13

申请人： Chun-Jen Liao ,  Sheng-Hong Tseng ,  Huang-Chien Liang ,  Yi-Chun Su ,  Pei-Chi Hsu

发明人： Chun-Jen Liao ,  Sheng-Hong Tseng ,  Huang-Chien Liang ,  Yi-Chun Su ,  Pei-Chi Hsu

IPC分类号： A61K38/39 ,  A61K9/12 ,  A61K38/01 ,  A61K8/65

CPC分类号： A61L26/0085 ,  A61K8/65 ,  A61K9/12 ,  A61K38/014 ,  A61K38/39 ,  A61L26/0023 ,  A61L26/0033 ,  A61L26/0052 ,  A61L26/0066 ,  A61L26/0076 ,  A61L27/20 ,  A61L27/24 ,  A61L27/26 ,  A61L27/56 ,  A61L2300/412 ,  A61L2300/60 ,  B65D83/752 ,  C08L5/08 ,  C08L89/06

摘要： A kit for producing a foamed biocompatible material includes a container configured to sustain a high pressure, and a tissue-repair composition placed in the container. The composition contains a biocompatible material, a liquid carrier, and a gas. The container has an internal pressure of greater than 1 atm and less than 250 atm, and includes a valve and a nozzle for releasing from the nozzle a foam formed of the composition upon opening the valve. Methods of producing and applying the biocompatible material are also disclosed.

摘要翻译： 用于生产泡沫生物相容性材料的试剂盒包括构造成维持高压的容器和置于容器中的组织修复组合物。 该组合物含有生物相容性材料，液体载体和气体。 容器的内部压力大于1atm且小于250atm，并且包括阀和喷嘴，用于在打开阀门时从喷嘴释放由组合物形成的泡沫。 还公开了生物和应用生物相容性材料的方法。

公开(公告)号：US08623641B2

公开(公告)日：2014-01-07

申请号：US12104685

申请日：2008-04-17

申请人： Chung-Nun Chen ,  Chun-Jen Liao ,  Chin-Yu Lin ,  Chin-Fu Chen ,  Yung-chih Wu

发明人： Chung-Nun Chen ,  Chun-Jen Liao ,  Chin-Yu Lin ,  Chin-Fu Chen ,  Yung-chih Wu

IPC分类号： C12M1/00 ,  C12M3/00 ,  B01L3/02 ,  G01N21/75 ,  G01N31/22 ,  G01N33/52 ,  G01N1/14 ,  G01N1/22

CPC分类号： B08B3/102 ,  B01L3/502 ,  B01L2300/045 ,  B01L2300/046 ,  B01L2300/0681 ,  B01L2300/0832 ,  B01L2400/0478 ,  C12M47/12

摘要： In a general aspect, an apparatus for washing biological material is provided which includes an outer sleeve, and an inner sleeve disposed within the outer sleeve. The outer sleeve has an open end for receiving the biological material, and an opposed closed end. The inner sleeve is detachably and slidably positioned within the outer sleeve, and includes a first port for receiving and dispensing washing liquid, a second port defining a liquid flow path between an interior of the inner sleeve and an interior of the outer sleeve, and a filter disposed in the second port. The filter allows passage of washing liquid but not passage of the biological material therethrough. A chamber, formed between the filter and the closed end of the outer sleeve, is configured to permit flow of washing liquid via the filter while retaining the biological material therein.

摘要翻译： 在一般方面，提供了一种用于洗涤生物材料的装置，其包括外套筒和设置在外套筒内的内套筒。 外套筒具有用于接收生物材料的开口端和相对的封闭端。 所述内套筒可拆卸地且可滑动地定位在所述外套筒内，并且包括用于接收和分配清洗液体的第一端口，限定在所述内套筒的内部和所述外套筒的内部之间的液体流路的第二端口， 过滤器设置在第二端口中。 过滤器允许洗涤液体通过，但不允许生物材料通过。 形成在过滤器和外套管的封闭端之间的室被构造成允许经由过滤器流动清洗液体，同时将生物材料保持在其中。