公开(公告)号：US07626031B2

公开(公告)日：2009-12-01

申请号：US10533555

申请日：2003-11-14

申请人： Wei Xu ,  Erick Wang Co ,  John M. Nuss ,  Moon Hwan Kim ,  Rhett Ronald Klein ,  Donna Tra Le ,  Amy Lew Tsuhako ,  Jason Jevious Parks ,  Zhaoyang Wen ,  Wei Cheng

发明人： Wei Xu ,  Erick Wang Co ,  John M. Nuss ,  Moon Hwan Kim ,  Rhett Ronald Klein ,  Donna Tra Le ,  Amy Lew Tsuhako ,  Jason Jevious Parks ,  Zhaoyang Wen ,  Wei Cheng

IPC分类号： C07D401/00 ,  A61K31/445

CPC分类号： C07D403/14 ,  C07D401/14 ,  C07D413/14 ,  C07D451/04

摘要： The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. More specifically, the invention provides oxindole derivatives which inhibit, regulate and/or modulate kinase receptor, particularly VEGF receptor 2 (Flk-1/KDR), FGFR1, and PDGFR (alpha and beta), signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions.

摘要翻译： 本发明提供调节蛋白激酶酶活性以调节细胞活性如增殖，分化，程序性细胞死亡，迁移和化学侵蚀的化合物。 更具体地，本发明提供抑制，调节和/或调节激酶受体，特别是VEGF受体2（Flk-1 / KDR），FGFR1和PDGFR（α和β）的信号转导途径的羟吲哚衍生物，其与细胞的变化相关 如上所述的活性，含有这些化合物的组合物，以及使用它们治疗激酶依赖性疾病和病症的方法。

公开(公告)号：US20080096892A1

公开(公告)日：2008-04-24

申请号：US10569873

申请日：2004-08-27

申请人： Wei Cheng ,  Erick Wang Co ,  Moon Hwan Kim ,  Rhett Ronald Klein ,  Donna T. Le ,  Amy Lew Tsuhako ,  John M. Nuss ,  Wei Xu ,  William Bajjalieh

发明人： Wei Cheng ,  Erick Wang Co ,  Moon Hwan Kim ,  Rhett Ronald Klein ,  Donna T. Le ,  Amy Lew Tsuhako ,  John M. Nuss ,  Wei Xu ,  William Bajjalieh

IPC分类号： A61K31/498 ,  C07D257/04 ,  A61K31/41 ,  C07D249/06 ,  A61K31/4192 ,  C07C233/15 ,  A61K31/505 ,  A61K31/4406 ,  C12N5/06 ,  C12Q1/48 ,  G01N33/566 ,  C07D213/30 ,  C07D239/26 ,  A61K31/167 ,  C07D249/08 ,  A61K31/4196 ,  C07D241/42

CPC分类号： A61K31/41 ,  A61K31/495 ,  C07D207/333 ,  C07D207/404 ,  C07D209/12 ,  C07D213/30 ,  C07D215/14 ,  C07D239/26 ,  C07D241/12 ,  C07D249/06 ,  C07D257/04 ,  C07D261/08 ,  C07D307/42 ,  C07D307/91 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12 ,  C07D417/12 ,  C07D471/04

摘要： The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellu-lar activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Even more specifically, the invention provides compounds for modulating c-Kit kinase activity and methods of treating diseases mediated by c-Kit activity utilizing the compounds and pharmaceutical compositions thereof.

摘要翻译： 本发明提供用于调节蛋白激酶酶活性以调节纤维细胞活性如增殖，分化，程序性细胞死亡，迁移和化学侵蚀的化合物。 甚至更具体地，本发明提供了用于调节c-Kit激酶活性的化合物和使用其化合物及其药物组合物治疗由c-Kit活性介导的疾病的方法。

公开(公告)号：US20060122171A1

公开(公告)日：2006-06-08

申请号：US10533555

申请日：2003-11-14

申请人： Wei Xu ,  Lynne Canne Bannen ,  Samuel Brown ,  Erick Co ,  John Nuss ,  Moon Kim ,  Rhett Klein ,  Donna Lee ,  Amy Tsuhako ,  Morrison Mac ,  Jason Parks ,  Zhaoyang Wen ,  Wei Cheng

发明人： Wei Xu ,  Lynne Canne Bannen ,  Samuel Brown ,  Erick Co ,  John Nuss ,  Moon Kim ,  Rhett Klein ,  Donna Lee ,  Amy Tsuhako ,  Morrison Mac ,  Jason Parks ,  Zhaoyang Wen ,  Wei Cheng

IPC分类号： A61K31/55 ,  A61K31/454 ,  C07D403/14

CPC分类号： C07D403/14 ,  C07D401/14 ,  C07D413/14 ,  C07D451/04

摘要： The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. More specifically, the invention provides oxindole derivatives which inhibit, regulate and/or modulate kinase receptor, particularly VEGF receptor 2 (Flk-1/KDR), FGFR1, and PDGFR (alpha and beta), signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions.

摘要翻译： 本发明提供调节蛋白激酶酶活性以调节细胞活性如增殖，分化，程序性细胞死亡，迁移和化学侵蚀的化合物。 更具体地，本发明提供抑制，调节和/或调节激酶受体，特别是VEGF受体2（Flk-1 / KDR），FGFR1和PDGFR（α和β）的信号转导途径的羟吲哚衍生物，其与细胞的变化相关 如上所述的活性，含有这些化合物的组合物，以及使用它们治疗激酶依赖性疾病和病症的方法。

公开(公告)号：US20050070172A1

公开(公告)日：2005-03-31

申请号：US10951504

申请日：2004-09-27

申请人： Wei Cheng ,  Hai Fang

发明人： Wei Cheng ,  Hai Fang

IPC分类号： H01R13/405 ,  H01R43/24

CPC分类号： H01R43/24 ,  H01R13/405 ,  Y10S439/936

摘要： A method of making a micro coaxial connector comprises the steps of: providing a number of terminals (20), assembling the terminals to an insulative first housing (10) to achieve a semi finished connector (100′), and molding the semi finished connector to a finished connector (100) with additional melt plastic. The melt plastic is formed into a second housing (13) and the terminals are retained by the first and second housings.

摘要翻译： 一种制造微型同轴连接器的方法包括以下步骤：提供多个端子（20），将端子组装到绝缘的第一壳体（10）以实现半成品连接器（100'），并且将半成品连接器 到具有附加熔体塑料的成品连接器（100）。 熔融塑料形成第二壳体（13），端子由第一和第二壳体保持。

公开(公告)号：US20170217522A1

公开(公告)日：2017-08-03

申请号：US15487446

申请日：2017-04-14

申请人： Wei Cheng ,  Ching Hsing Lu

发明人： Wei Cheng ,  Ching Hsing Lu

IPC分类号： B62J1/16 ,  B62J99/00 ,  B62J1/08 ,  B62J25/00

CPC分类号： B62J1/167 ,  B62J1/08 ,  B62J25/00 ,  B62J99/00 ,  B62K2206/00

摘要： A child bicycle seat releasably mounted to a bicycle includes a seat assembly including a child seat secured to a tube member, a front tube mounted to a front end of the tube member and having top and bottom cavities, and a quick release clamp mounted to a rear end of the tube member; a handlebar assembly including a hollow pole having two opposite lower slots, a handlebar member threadedly secured to a top of the hollow pole, and a first quick release skewer secured to both the top cavity and the lower slots to fasten the front tube and the hollow pole together; a clamp assembly including a top tube having two opposite slot members, a second quick release skewer secured to both the bottom cavity and the slot members to fasten the front tube and the top tube together. The clamp assembly has a height adjustment mechanism.

公开(公告)号：US09109087B2

公开(公告)日：2015-08-18

申请号：US13613353

申请日：2012-09-13

申请人： Wei Cheng ,  Daniel J. Coady ,  Amanda C. Engler ,  James L. Hedrick ,  Pei Yun Teo ,  Chuan Yang ,  Yi Yan Yang

发明人： Wei Cheng ,  Daniel J. Coady ,  Amanda C. Engler ,  James L. Hedrick ,  Pei Yun Teo ,  Chuan Yang ,  Yi Yan Yang

IPC分类号： A61K47/30 ,  C07D321/00 ,  C07H21/00 ,  C08G73/02

CPC分类号： C08G73/0206

摘要： A branched polyamine comprises about 8 to about 12 backbone tertiary amine groups, about 18 to about 24 backbone secondary amine groups, a positive number n′ greater than 0 of backbone terminating primary amine groups, and a positive number q greater than 0 of backbone terminating carbamate groups of formula (2): wherein (n′+q) is a number equal to about 8 to about 12, the starred bond of formula (2) is linked to a backbone nitrogen of the branched polyamine, L′ is a divalent linking group comprising 3 to 30 carbons, and q/(n′+q)×100% equals about 9% to about 40%.

摘要翻译： 支链多胺包含约8至约12个骨架叔胺基团，约18至约24个骨架仲胺基团，正数n'大于0的主链终止伯胺基团，正数q大于0的骨架终止 式（2）的氨基甲酸酯基团：其中（n'+ q）是等于约8至约12的数，式（2）的星形键与支链多胺的主链氮连接，L'是二价 包含3至30个碳的连接基团，q /（n'+ q）×100％等于约9％至约40％。

公开(公告)号：US20120054107A1

公开(公告)日：2012-03-01

申请号：US12868803

申请日：2010-08-26

申请人： Sanjeev Kumar Biswas ,  Kanika Dalmia Gupta ,  Vikalp Gupta ,  Daniel C. Brotsky ,  Wei Cheng ,  Vivek Misra

发明人： Sanjeev Kumar Biswas ,  Kanika Dalmia Gupta ,  Vikalp Gupta ,  Daniel C. Brotsky ,  Wei Cheng ,  Vivek Misra

IPC分类号： G06F21/00

CPC分类号： G06F21/10 ,  G06Q30/06

摘要： One exemplary embodiment provides a synchronization device for updating information stored at a first device used for account management of a subscription for a software product. The synchronization device receives a status of the subscription from a second device that provides billing transactions associated with the subscription. The second device maintains the status of the subscription to reflect changes based on the billing transactions associated with the subscription. Based at least in part on the status of the subscription received at the synchronization device from the second device, the synchronization device provides information for the first device to update a status of the account associated with the subscription.

摘要翻译： 一个示例性实施例提供了一种同步装置，用于更新存储在用于软件产品的订阅的帐户管理的第一设备处的信息。 同步设备从提供与订阅相关联的计费交易的第二设备接收订阅的状态。 第二个设备维护订阅的状态以基于与订阅相关联的计费交易来反映更改。 至少部分地基于从第二设备在同步设备处接收的订阅的状态，同步设备为第一设备提供信息以更新与订阅相关联的帐户的状态。

公开(公告)号：US20070013587A1

公开(公告)日：2007-01-18

申请号：US11233781

申请日：2005-09-23

申请人： Chih Liu ,  Wei Cheng

发明人： Chih Liu ,  Wei Cheng

IPC分类号： H01Q1/24

CPC分类号： H01Q1/36 ,  G06F1/1616 ,  G06F1/1698 ,  H01Q1/2266 ,  H01Q5/371 ,  H01Q9/42 ,  H01Q21/30

摘要： An antenna comprises a ground element, a conductive element, a signal line, a first transmitting element, a second transmitting element. The conductive element is L-shaped and connected to the ground element. The signal line is coupled to the conductive element. The first transmitting element is connected to the conductive element for transmitting a first signal. The second transmitting element is connected to the conductive element for transmitting a second signal. The first signal is a GSM900 signal and the second signal is a DCS1800 signal.

公开(公告)号：US20050287860A1

公开(公告)日：2005-12-29

申请号：US11100828

申请日：2005-04-06

申请人： Hao Yin ,  Wei Cheng

发明人： Hao Yin ,  Wei Cheng

IPC分类号： H01R9/22 ,  H01R13/639 ,  H01R31/06

CPC分类号： H01R31/06 ,  H01R13/6395 ,  H01R2201/06

摘要： An electrical connector (100) includes a module (1) having a mating portion (115) embedded with a plurality of terminals (13), an interlocking member having a press member (6) and an elongated latch member (5) assembled with the press member, and an insulative casing (3, 4) forming an extension (36, 46) to enclose the mating portion of the module and the latch member of the interlocking member.

摘要翻译： 电连接器（100）包括具有嵌入多个端子（13）的配合部分（115）的模块（1），具有按压构件（6）的互锁构件和与 压力构件和形成延伸部（36,46）的绝缘壳体（3,4），以封闭模块的配合部分和互锁构件的闩锁构件。

公开(公告)号：US09906431B2

公开(公告)日：2018-02-27

申请号：US15156925

申请日：2016-05-17

申请人： Wei Cheng

发明人： Wei Cheng

IPC分类号： H04L12/751 ,  H04W4/02 ,  H04L12/733 ,  H04W40/20 ,  H04W84/18 ,  H04W8/00

CPC分类号： H04L45/02 ,  H04L45/20 ,  H04W4/02 ,  H04W8/005 ,  H04W40/20 ,  H04W84/18 ,  Y02D70/142 ,  Y02D70/164 ,  Y02D70/22 ,  Y02D70/38

摘要： Time-critical Location Based Service (LBS) applications in mobile ad hoc networks (MANETs) require fast localization. An On-Demand Fast Localization (ODFL) start from multi-coordinate systems, and the position transformation is integrated with LBS application information transmissions. The framework of ODFL turns two pipe-lined procedures into two semi-concurrent procedures by employing coordinate system transformation on a per hop basis, which consists of three components: (1) Local Coordinate System (LCS) construction; (2) embedded information selection; and (3) position transformation.