Sterile De-Molding Apparatus and Method
    31.
    发明申请
    Sterile De-Molding Apparatus and Method 有权
    无菌脱模装置及方法

    公开(公告)号:US20110113729A1

    公开(公告)日:2011-05-19

    申请号:US13012074

    申请日:2011-01-24

    CPC classification number: B65B3/022

    Abstract: Apparatus for molding and filling a device having a body defining an opening in communication with an interior chamber for receiving a substance therein, and a closure including a penetrable and resealable portion for sealing the opening and substance received in the device. A mold includes within the aseptic chamber plural mold cavities shaped to form the closure and body, and substantially sterile surfaces extending about and contiguous to the peripheries of the mold cavities. An assembly device including end-of-arm tooling having an engaging portion engageable with each of the body and closure is movable relative to the mold to engage and de-mold the substantially sterile closures and bodies from the mold cavities. Flexible barriers are coupled to the mold and the tool to substantially prevent the passage of contaminants from the molding machine and tool therethrough.

    Abstract translation: 用于模制和填充具有本体的装置的装置,该主体限定与用于在其中容纳物质的内部腔室连通的开口;以及封闭件,包括用于密封容纳在装置中的开口和物质的可穿透和可重新密封的部分。 模具包括在无菌室内的多个模具腔,其形状形成封闭件和主体,以及基本上无菌的表面,其围绕并邻近模具腔的周边延伸。 包括端臂工具的组装装置具有可与主体和闭合件中的每一个接合的接合部分,其可相对于模具移动以将基本无菌的闭合件和主体与模腔接合和脱模。 柔性屏障耦合到模具和工具,以基本上防止污染物从模制机器和工具通过。

    Adjustable Needle Filling and Laser Sealing Apparatus and Method
    32.
    发明申请
    Adjustable Needle Filling and Laser Sealing Apparatus and Method 有权
    可调针式灌装和激光密封装置及方法

    公开(公告)号:US20100276030A1

    公开(公告)日:2010-11-04

    申请号:US12627655

    申请日:2009-11-30

    Abstract: An assembly includes a support and drive assembly, a first structure and a second structure. The first structure is in operable communication with and supported by the support and drive assembly. The first structure includes at least one needle assembly and is adjustable to receive a plurality of needle assemblies. The second structure is supported by the support and drive assembly. The second structure includes at least one seal assembly and is adjustable to receive a plurality of seal assemblies. A method includes determining a number of vials that are to be filled concurrently and adjusting an assembly to include at least one needle assembly and at least one seal assembly. A number of the needle assemblies and the seal assemblies equals the number of vials.

    Abstract translation: 组件包括支撑和驱动组件,第一结构和第二结构。 第一结构与支撑和驱动组件可操作地连通并由其支撑。 第一结构包括至少一个针组件,并且可调节以接收多个针组件。 第二个结构由支撑和驱动组件支撑。 第二结构包括至少一个密封组件,并且可调节以接收多个密封组件。 一种方法包括确定要同时填充的小瓶的数量并且调整组件以包括至少一个针组件和至少一个密封组件。 许多针组件和密封组件等于小瓶的数量。

    STERILE DE-MOLDING APPARATUS AND METHOD
    33.
    发明申请
    STERILE DE-MOLDING APPARATUS AND METHOD 有权
    STERILE脱模装置和方法

    公开(公告)号:US20090145089A1

    公开(公告)日:2009-06-11

    申请号:US12371601

    申请日:2009-02-14

    CPC classification number: B65B3/022

    Abstract: Apparatus for molding and filling a device having a body defining an opening in communication with an interior chamber for receiving a substance therein, and a closure including a penetrable and resealable portion for sealing the opening and substance received in the device. A mold includes within the aseptic chamber plural mold cavities shaped to form the closure and body, and substantially sterile surfaces extending about and contiguous to the peripheries of the mold cavities. An assembly device including end-of-arm tooling having an engaging portion engageable with each of the body and closure is movable relative to the mold to engage and de-mold the substantially sterile closures and bodies from the mold cavities. Flexible barriers are coupled to the mold and the tool to substantially prevent the passage of contaminants from the molding machine and tool therethrough.

    Abstract translation: 用于模制和填充具有本体的装置的装置,该主体限定与用于在其中容纳物质的内部腔室连通的开口;以及封闭件,包括用于密封容纳在装置中的开口和物质的可穿透和可重新密封的部分。 模具包括在无菌室内的多个模具腔,其形状形成封闭件和主体,以及基本上无菌的表面,其围绕并邻近模具腔的周边延伸。 包括端臂工具的组装装置具有可与主体和闭合件中的每一个接合的接合部分,其可相对于模具移动以将基本无菌的闭合件和主体与模腔接合和脱模。 柔性屏障耦合到模具和工具,以基本上防止污染物从模制机器和工具通过。

    Method of using one-way valve and related apparatus
    34.
    发明申请
    Method of using one-way valve and related apparatus 有权
    使用单向阀及相关设备的方法

    公开(公告)号:US20060169722A1

    公开(公告)日:2006-08-03

    申请号:US11295251

    申请日:2005-12-05

    Abstract: An apparatus has a valve body defining a first passageway, a valve seat, and a flow aperture extending through the valve body and coupled in fluid communication with the first passageway. A valve cover of the apparatus is formed of an elastic material and includes a cover base mounted on the valve body and fixedly secured against movement relative thereto, and a valve portion overlying the valve seat. The valve portion defines a predetermined radial thickness and forms an interference fit with the valve seat. The valve portion and the valve seat define a normally closed, axially-extending valve opening therebetween. The valve portion is movable between a normally closed position with the valve portion engaging the valve seat, and an open position with at least a segment of the valve portion spaced away from the valve seat to connect the valve opening in fluid communication with the flow aperture to thereby allow the passage of fluid from the flow aperture through the valve opening. A hermetically sealed variable-volume storage chamber stores therein multiple portions of the fluid and is connectible in fluid communication with the one-way valve assembly. A pump is coupled between the variable-volume storage chamber and the one-way valve assembly, and is configured to pump discrete portions of fluid from the variable-volume storage chamber, through the flow aperture, and through the valve opening to dispense the portions of fluid through the valve assembly.

    Abstract translation: 一种装置具有限定第一通道,阀座和延伸穿过阀体并与第一通道流体连通地联接的流动孔的阀体。 该装置的阀盖由弹性材料形成,并且包括安装在阀体上的盖基座,并且固定地抵靠其相对移动,以及覆盖在阀座上的阀部分。 阀部分限定预定的径向厚度并与阀座形成过盈配合。 阀部分和阀座限定了其间的常闭的,轴向延伸的阀开口。 阀部分可以在与阀座接合的阀部分的常闭位置和打开位置之间移动,打开位置具有与阀座间隔开的阀部分的至少一段,以连接与开口流体连通的阀开口 从而允许流体从流动孔通过阀开口。 气密密封的可变容积储存室在其中存储有多个流体部分,并可与单向阀组件流体连通。 泵连接在可变容积存储室和单向阀组件之间,并且构造成从可变容积储存室通过流动孔泵送离散的流体部分,并且通过阀开口分配部分 的流体通过阀组件。

    One-way valve and apparatus using the valve
    35.
    发明申请
    One-way valve and apparatus using the valve 有权
    单向阀和使用阀门的装置

    公开(公告)号:US20060151051A1

    公开(公告)日:2006-07-13

    申请号:US11295274

    申请日:2005-12-05

    Abstract: An apparatus has a valve body defining a first passageway, a valve seat, and a flow aperture extending through the valve body and coupled in fluid communication with the first passageway. A valve cover of the apparatus is formed of an elastic material and includes a cover base mounted on the valve body and fixedly secured against movement relative thereto, and a valve portion overlying the valve seat. The valve portion defines a predetermined radial thickness and forms an interference fit with the valve seat. The valve portion and the valve seat define a normally closed, axially-extending valve opening therebetween. The valve portion is movable between a normally closed position with the valve portion engaging the valve seat, and an open position with at least a segment of the valve portion spaced away from the valve seat to connect the valve opening in fluid communication with the flow aperture to thereby allow the passage of fluid from the flow aperture through the valve opening. A hermetically sealed variable-volume storage chamber stores therein multiple portions of the fluid and is connectible in fluid communication with the one-way valve assembly. A pump is coupled between the variable-volume storage chamber and the one-way valve assembly, and is configured to pump discrete portions of fluid from the variable-volume storage chamber, through the flow aperture, and through the valve opening to dispense the portions of fluid through the valve assembly.

    Abstract translation: 一种装置具有限定第一通道,阀座和延伸穿过阀体并与第一通道流体连通地联接的流动孔的阀体。 该装置的阀盖由弹性材料形成,并且包括安装在阀体上的盖基座,并且固定地抵靠其相对移动,以及覆盖在阀座上的阀部分。 阀部分限定预定的径向厚度并与阀座形成过盈配合。 阀部分和阀座限定了其间的常闭的,轴向延伸的阀开口。 阀部分可以在与阀座接合的阀部分的常闭位置和打开位置之间移动,打开位置具有与阀座间隔开的阀部分的至少一段,以连接与开口流体连通的阀开口 从而允许流体从流动孔通过阀开口。 气密密封的可变容积储存室在其中存储有多个流体部分,并可与单向阀组件流体连通。 泵连接在可变容积存储室和单向阀组件之间,并且构造成从可变容积储存室通过流动孔泵送离散的流体部分,并且通过阀开口分配部分 的流体通过阀组件。

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