公开(公告)号：US20080224101A1

公开(公告)日：2008-09-18

申请号：US11841640

申请日：2007-08-20

申请人： Chunming Niu ,  Lein Ngaw ,  Alan Fischer ,  Robert Hoch

发明人： Chunming Niu ,  Lein Ngaw ,  Alan Fischer ,  Robert Hoch

IPC分类号： H01B1/06

CPC分类号： C08J3/212 ,  B82Y10/00 ,  B82Y30/00 ,  C08J2327/16 ,  C08K7/24 ,  H01B1/24 ,  Y10S977/742 ,  Y10S977/788 ,  C08L27/16

摘要： An electrically conductive composite comprising a polyvinylidene fluoride polymer or copolymer and carbon nanotubes is provided. Preferably, carbon nanotubes may be present in the range of about 0.5-20% by weight of the composite.The composites are prepared by dissolving the polymer in a first solvent to form a polymer solution and then adding the carbon nanotubes into the solution. The solution is mixed using an energy source such as a sonicator or a Waring blender. A precipitating component is added to precipitate out a composite comprising the polymer and the nanotubes. The composite is isolated by filtering the solution and drying the composite.

摘要翻译： 提供了包含聚偏二氟乙烯聚合物或共聚物和碳纳米管的导电复合材料。 优选地，碳纳米管可以以该复合材料的约0.5-20重量％的范围存在。 通过将聚合物溶解在第一溶剂中以形成聚合物溶液，然后将碳纳米管加入到溶液中来制备复合材料。 使用诸如超声波发生器或Waring混合器的能量源将溶液混合。 加入沉淀组分以沉淀出包含聚合物和纳米管的复合材料。 通过过滤溶液并干燥复合物来分离复合物。

公开(公告)号：US20060172340A1

公开(公告)日：2006-08-03

申请号：US11300808

申请日：2005-12-14

申请人： Jacob Wohlstadter ,  James Wilbur ,  George Sigal ,  Mark Martin ,  Liang-Hong Guo ,  Alan Fischer ,  Jon Leland ,  Mark Billadeau

发明人： Jacob Wohlstadter ,  James Wilbur ,  George Sigal ,  Mark Martin ,  Liang-Hong Guo ,  Alan Fischer ,  Jon Leland ,  Mark Billadeau

IPC分类号： G01N33/53 ,  C12M1/34

CPC分类号： G01N21/66 ,  B82Y15/00 ,  B82Y30/00 ,  G01N21/76 ,  G01N33/54313 ,  G01N33/5438 ,  G01N33/582 ,  G01N33/585 ,  Y10S435/808 ,  Y10S435/81 ,  Y10S435/968 ,  Y10S435/975 ,  Y10S436/805

摘要： Materials and methods are provided for producing patterned multi-array, multi-specific surfaces for use in diagnostics. The invention provides for electrochemiluminescence methods for detecting or measuring an analyte of interest. It also provides for novel electrodes for ECL assays. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use multiply specific testing procedures.

公开(公告)号：US20060160246A1

公开(公告)日：2006-07-20

申请号：US11385277

申请日：2006-03-20

申请人： Richard Massey ,  Mark Martin ,  Liwen Dong ,  Ming Lu ,  Alan Fischer ,  Fabian Jameison ,  Pam Liang ,  Robert Hoch ,  Jonathan Leland

发明人： Richard Massey ,  Mark Martin ,  Liwen Dong ,  Ming Lu ,  Alan Fischer ,  Fabian Jameison ,  Pam Liang ,  Robert Hoch ,  Jonathan Leland

IPC分类号： G01N33/543 ,  C12M1/34

CPC分类号： C01B31/0213 ,  B82Y30/00 ,  B82Y40/00 ,  C01B32/152 ,  C01B32/174 ,  C01B2202/34 ,  C01B2202/36 ,  C07K17/06 ,  D01F9/12 ,  D01F11/14 ,  G01N21/69 ,  G01N21/76 ,  G01N33/54373 ,  G01N33/5438 ,  G01N33/582 ,  G01N2030/8863 ,  G11C13/025 ,  H01M4/60 ,  Y10S435/968 ,  Y10S436/805 ,  Y10S436/806 ,  Y10S977/737 ,  Y10S977/742

摘要： Graphitic nanotubes, which include tubular fullerenes (commonly called “buckytubes”) and fibrils, which are functionalized by chemical substitution, are used as solid supports in electrogenerated chemiluminescence assays. The graphitic nanotubes are chemically modified with functional group biomolecules prior to use in an assay. Association of electrochemiluminescent ruthenium complexes with the functional group biomolecule-modified nanotubes permits detection of molecules including nucleic acids, antigens, enzymes, and enzyme substrates by multiple formats.

公开(公告)号：US07015046B2

公开(公告)日：2006-03-21

申请号：US10693441

申请日：2003-10-24

申请人： Jacob N. Wohlstadter ,  James Wilbur ,  George Sigal ,  Mark Martin ,  Liang-Hong Guo ,  Alan Fischer ,  Jon Leland ,  Mark A. Billadeau ,  Larry R. Helms ,  Ramin Darvari

发明人： Jacob N. Wohlstadter ,  James Wilbur ,  George Sigal ,  Mark Martin ,  Liang-Hong Guo ,  Alan Fischer ,  Jon Leland ,  Mark A. Billadeau ,  Larry R. Helms ,  Ramin Darvari

IPC分类号： G01N21/76

CPC分类号： G01N21/76 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2300/0636 ,  B01L2300/0645 ,  B82Y15/00 ,  B82Y30/00 ,  C12Q1/6825 ,  G01N21/253 ,  G01N21/66 ,  G01N33/54313 ,  G01N33/5438 ,  G01N33/582 ,  G01N33/585 ,  Y10S435/808 ,  Y10S435/817 ,  Y10S436/805 ,  Y10S436/806 ,  Y10S436/807

摘要： Materials and methods are provided for producing patterned multi-array, multi-specific surfaces for use in diagnostics. The invention provides for electrochemiluminescence methods for detecting or measuring an analyte of interest. It also provides for novel electrodes for ECL assays. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use multiply specific testing procedures.

公开(公告)号：US06783702B2

公开(公告)日：2004-08-31

申请号：US09903189

申请日：2001-07-11

申请人： Chunming Niu ,  Lein Ngaw ,  Alan Fischer ,  Robert Hoch

发明人： Chunming Niu ,  Lein Ngaw ,  Alan Fischer ,  Robert Hoch

IPC分类号： H01G124

CPC分类号： C08J3/212 ,  B82Y10/00 ,  B82Y30/00 ,  C08J2327/16 ,  C08K7/24 ,  H01B1/24 ,  Y10S977/742 ,  Y10S977/788 ,  C08L27/16

摘要： An electrically conductive composite comprising a polyvinylidene fluoride polymer or copolymer and carbon nanotubes is provided. Preferably, carbon nanotubes may be present in the range of about 0.5-20% by weight of the composite. The composites are prepared by dissolving the polymer in a first solvent to form a polymer solution and then adding the carbon nanotubes into the solution. The solution is mixed using an energy source such as a sonicator or a Waring blender. A precipitating component is added to precipitate out a composite comprising the polymer and the nanotubes. The composite is isolated by filtering the solution and drying the composite.

摘要翻译： 提供了包含聚偏二氟乙烯聚合物或共聚物和碳纳米管的导电复合材料。 优选地，碳纳米管可以在复合材料的约0.5-20重量％的范围内。通过将聚合物溶解在第一溶剂中以形成聚合物溶液，然后将碳纳米管加入到溶液中来制备复合材料。 使用诸如超声波发生器或Waring混合器的能量源将溶液混合。 加入沉淀组分以沉淀出包含聚合物和纳米管的复合材料。 通过过滤溶液并干燥复合物来分离复合物。

公开(公告)号：US06362011B1

公开(公告)日：2002-03-26

申请号：US09243215

申请日：1999-02-02

申请人： Richard J. Massey ,  Mark T. Martin ,  Liwen Dong ,  Ming Lu ,  Alan Fischer ,  Fabian Jameison ,  Pam Liang ,  Robert Hoch ,  Jonathan K. Leland

发明人： Richard J. Massey ,  Mark T. Martin ,  Liwen Dong ,  Ming Lu ,  Alan Fischer ,  Fabian Jameison ,  Pam Liang ,  Robert Hoch ,  Jonathan K. Leland

IPC分类号： G01N33551

CPC分类号： C01B31/0213 ,  B82Y30/00 ,  B82Y40/00 ,  C01B32/152 ,  C01B32/174 ,  C01B2202/34 ,  C01B2202/36 ,  C07K17/06 ,  D01F9/12 ,  D01F11/14 ,  G01N21/69 ,  G01N21/76 ,  G01N33/54373 ,  G01N33/5438 ,  G01N33/582 ,  G01N2030/8863 ,  G11C13/025 ,  H01M4/60 ,  Y10S435/968 ,  Y10S436/805 ,  Y10S436/806 ,  Y10S977/737 ,  Y10S977/742

摘要： Graphitic nanotubes, which include tubular fullerenes (commonly called “buckytubes”) and fibrils, which are functionalized by chemical substitution, are used as solid supports in electrogenerated chemiluminescence assays. The graphitic nanotubes are chemically modified with functional group biomolecules prior to use in an assay. Association of electrochemiluminescent ruthenium complexes with the functional group biomolecule-modified nanotubes permits detection of molecules including nucleic acids, antigens, enzymes, and enzyme substrates by multiple formats.

摘要翻译： 石墨纳米管，其包括通过化学取代官能化的管状富勒烯（通常称为“巴氏管”）和原纤维，被用作电致化学发光测定中的固体支持物。 石墨纳米管在用于测定之前用官能团生物分子进行化学修饰。 电化学发光钌络合物与官能团生物分子修饰的纳米管的关联允许通过多种形式检测包括核酸，抗原，酶和酶底物的分子。

公开(公告)号：US5866434A

公开(公告)日：1999-02-02

申请号：US611347

申请日：1996-03-06

申请人： Richard J. Massey ,  Mark T. Martin ,  Liwen Dong ,  Ming Lu ,  Alan Fischer ,  Fabian Jameison ,  Pam Liang ,  Robert Hoch ,  Jonathan K. Leland

发明人： Richard J. Massey ,  Mark T. Martin ,  Liwen Dong ,  Ming Lu ,  Alan Fischer ,  Fabian Jameison ,  Pam Liang ,  Robert Hoch ,  Jonathan K. Leland

IPC分类号： B01J20/281 ,  A61K47/04 ,  B01J20/20 ,  B01J21/18 ,  B01J32/00 ,  C01B31/02 ,  C07K16/44 ,  C07K17/06 ,  D01F9/12 ,  D01F11/14 ,  G01N21/69 ,  G01N21/76 ,  G01N21/78 ,  G01N30/88 ,  G01N33/543 ,  G01N33/553 ,  G01N33/573 ,  G01N33/58 ,  H01M4/60 ,  G01N33/551 ,  C12Q1/32 ,  C12Q1/37

CPC分类号： C01B31/0213 ,  B82Y30/00 ,  B82Y40/00 ,  C01B31/0273 ,  C07K17/06 ,  D01F11/14 ,  D01F9/12 ,  G01N33/54373 ,  G01N33/5438 ,  G01N33/582 ,  H01M4/60 ,  C01B2202/34 ,  C01B2202/36 ,  G01N2030/8863 ,  G01N21/69 ,  G01N21/76 ,  G11C13/025 ,  Y10S435/968 ,  Y10S436/805 ,  Y10S436/806 ,  Y10S977/737 ,  Y10S977/742

摘要： Graphitic nanotubes, which include tubular fullerenes (commonly called "buckytubes") and fibrils, which are functionalized by chemical substitution, are used as solid supports in electrogenerated chemiluminescence assays. The graphitic nanotubes are chemically modified with functional group biomolecules prior to use in an assay. Association of electrochemiluminescent ruthenium complexes with the functional group biomolecule-modified nanotubes permits detection of molecules including nucleic acids, antigens, enzymes, and enzyme substrates by multiple formats.

公开(公告)号：US08541174B2

公开(公告)日：2013-09-24

申请号：US11300808

申请日：2005-12-14

申请人： Jacob N. Wohlstadter ,  James L. Wilbur ,  George B. Sigal ,  Mark T. Martin ,  Liang-Hong Guo ,  Alan Fischer ,  Jon Leland ,  Mark A. Billadeau

发明人： Jacob N. Wohlstadter ,  James L. Wilbur ,  George B. Sigal ,  Mark T. Martin ,  Liang-Hong Guo ,  Alan Fischer ,  Jon Leland ,  Mark A. Billadeau

IPC分类号： G01N33/53

CPC分类号： G01N21/66 ,  B82Y15/00 ,  B82Y30/00 ,  G01N21/76 ,  G01N33/54313 ,  G01N33/5438 ,  G01N33/582 ,  G01N33/585 ,  Y10S435/808 ,  Y10S435/81 ,  Y10S435/968 ,  Y10S435/975 ,  Y10S436/805

摘要： Materials and methods are provided for producing patterned multi-array, multi-specific surfaces for use in diagnostics. The invention provides for electrochemiluminescence methods for detecting or measuring an analyte of interest. It also provides for novel electrodes for ECL assays. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use multiply specific testing procedures.

摘要翻译： 提供材料和方法用于生产用于诊断的图案化多阵列多特异性表面。 本发明提供了用于检测或测量感兴趣分析物的电化学发光方法。 它还提供用于ECL测定的新型电极。 提供材料和方法用于化学和/或物理控制导电域和试剂沉积，以便使用多重特定的测试程序。

公开(公告)号：US08541168B1

公开(公告)日：2013-09-24

申请号：US09677799

申请日：2000-10-02

申请人： Jacob Wohlstadter ,  James Wilbur ,  George Sigal ,  Mark Martin ,  Liang-Hong Guo ,  Alan Fischer ,  Jon Leland

发明人： Jacob Wohlstadter ,  James Wilbur ,  George Sigal ,  Mark Martin ,  Liang-Hong Guo ,  Alan Fischer ,  Jon Leland

IPC分类号： G01N33/53

CPC分类号： G01N21/66 ,  B82Y30/00 ,  G01N21/76 ,  G01N33/5438 ,  G01N33/582 ,  Y10S435/808 ,  Y10S435/968 ,  Y10S435/973 ,  Y10S436/805 ,  Y10S436/806

摘要： Materials and methods are provided for producing patterned multi-array, multi-specific surfaces which are electronically excited for use in electrochemiluminescence based tests. Materials and methods are provided for the chemical and/or physical control of conducting domains and reagent deposition for use in flat panel displays and multiply specific testing procedures.

公开(公告)号：US08083970B2

公开(公告)日：2011-12-27

申请号：US10517748

申请日：2003-06-16

申请人： Jun Ma ,  Alan Fischer ,  Chunming Niu ,  Lein Ngaw

发明人： Jun Ma ,  Alan Fischer ,  Chunming Niu ,  Lein Ngaw

IPC分类号： H01B1/00 ,  H01B1/12

CPC分类号： H01C17/06586 ,  C09D5/24 ,  C09D11/52 ,  H01B1/24 ,  H01C17/0652 ,  H01G11/24 ,  H01G11/38 ,  Y02E60/13 ,  Y10S977/742 ,  Y10T428/25 ,  Y10T428/29 ,  Y10T428/30

摘要： The present invention relates to electroconductive inks and methods of making and using the same. The electroconductive inks include carbon fibrils and a liquid vehicle. The electroconductive ink may further include a polymeric binder. The electroconductive filler used is carbon fibrils which may be oxidized. The ink has rheological properties similar to that of commercially available electroconductive inks that use carbon black as their filler. The ink can be screen-printed, slot-coated, sprayed, brushed or dipped onto a wide variety of substrates to form an electroconductive coating.

摘要翻译： 本发明涉及导电油墨及其制造和使用方法。 导电油墨包括碳纤维和液体载体。 导电油墨还可以包括聚合物粘合剂。 所用的导电填料是可被氧化的碳原子纤维。 油墨具有类似于使用炭黑作为填料的市售导电油墨的流变性能。 油墨可以丝网印刷，槽涂，喷涂，刷涂或浸在各种基材上以形成导电涂层。