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48 条记录 (耗时 0.033 秒)

    Prefillable syringes and injectors for use therewith
    31.
    发明授权
    Prefillable syringes and injectors for use therewith 失效
    预先使用的注射器和注射器

    公开(公告)号：US06322535B1

    公开(公告)日：2001-11-27

    申请号：US09282941

    申请日：1999-04-01

    申请人： Mark W. Hitchins ,  Edward J. Rhinehart ,  Robert J. Masarik

    发明人： Mark W. Hitchins ,  Edward J. Rhinehart ,  Robert J. Masarik

    IPC分类号： A61M3700

    CPC分类号： A61M5/14546 ,  A61M5/14566

    摘要： The present invention provides prefillable syringes and injectors for use therewith that expand and/or facilitate a variety of medical procedures involving the injection of a liquid medium. In several embodiments, the present syringes and injectors enable the use of current syringe materials at higher pressures than previously attainable or the use of other materials not previously usable with current high pressure-syringe and injector designs. In one embodiment, a syringe comprises an elongated cylindrical main body having a first pair and a second pair of mounting flanges encompassing collectively an arcuate length equal to at least approximately 180° of the circumference of the rear portion of the cylindrical main body for releasably mounting the syringe in a desired position relative to the front wall of the injector housing. Injectors for use with such syringes comprise a housing having a front wall and a retainer on the front wall which cooperates with the first and second pairs of mounting flanges of the syringe to releasably mount the syringe on the injector.

    摘要翻译： 本发明提供了可与之一起使用的可预充注射器和注射器，其扩展和/或促进涉及注射液体介质的各种医疗过程。 在几个实施例中，本发明的注射器和注射器使得能够以比先前可获得的更高的压力使用当前的注射器材料，或者使用以前不能用于当前高压注射器和注射器设计的其它材料。 在一个实施例中，注射器包括细长的圆柱形主体，其具有第一对和第二对安装凸缘，其共同包含等于圆柱形主体的后部的圆周的至少约180°的弓形长度，用于可释放地安装 注射器相对于注射器壳体的前壁处于期望的位置。 用于这种注射器的注射器包括具有在前壁上的前壁和保持器的壳体，其与注射器的第一和第二对安装凸缘配合以将注射器可释放地安装在注射器上。

    Manufacture of prefilled syringes
    32.
    发明授权
    Manufacture of prefilled syringes 失效
    制造预充式注射器

    公开(公告)号：US06189195B1

    公开(公告)日：2001-02-20

    申请号：US08517645

    申请日：1995-08-22

    申请人： David M. Reilly ,  Edward J. Rhinehart ,  Eugene A. Gelblum ,  Mark W. Hitchins ,  Michelle Robinson

    发明人： David M. Reilly ,  Edward J. Rhinehart ,  Eugene A. Gelblum ,  Mark W. Hitchins ,  Michelle Robinson

    IPC分类号： B23P1500

    CPC分类号： B65B3/003 ,  Y10T29/49808 ,  Y10T29/4984

    摘要： This invention relates to a process for manufacturing prefilled syringes where at least one of the syringe components is manufactured in at least a class 100 environment. The process includes the steps of manufacturing syringe components, such as the barrel and plunger substrate, within at least a class 100 and MCB-3 environment; manufacturing syringe components, such as the plunger cover and tip seal in an environment less clean than a class 100 environment; decontaminating the plunger cover and tip seal; lubricating at least one of the barrel, plunger substrate, plunger cover and tip seal; assembling the barrel and tip seal to form a barrel/tip seal combination; assembling the plunger cover and plunger substrate to form a plunger; filling the barrel/tip seal combination with a predetermined amount of fluid; and final assembling of the prefilled syringe by inserting the plunger into the barrel/tip seal combination. When the syringe components are manufactured at different locations, each component is tripled-bagged to maintain the component substantially free from contaminants, and transported to an assembly site where the components are unpackaged and assembled into the barrel/tip seal combination and plunger. When filling and final assembly of the barrel/tip seal combination takes place at a location separate from its assembly site, the barrel/tip seal combination is tripled-bagged to maintain it substantially free from contaminants, and transported to a filling and final assembling site for filling and final assembling into a prefilled syringe.

    摘要翻译： 本发明涉及一种用于制造预充式注射器的方法，其中至少一个注射器组件在至少100级环境中制造。 该方法包括在至少100级和MCB-3环境中制造注射器部件（例如筒体和柱塞基底）的步骤; 在比100级环境更干净的环境中制造注射器部件，例如柱塞盖和末端密封; 净化柱塞盖和顶端密封; 润滑桶，柱塞基板，柱塞盖和端盖密封件中的至少一个; 组装筒和尖端密封以形成筒/尖端密封组合; 组装柱塞盖和柱塞基板以形成柱塞; 用预定量的流体填充桶/尖端密封组合; 以及通过将柱塞插入筒/尖端密封组合中来预填充注射器的最终组装。 当注射器组件在不同位置制造时，每个组件被三倍重装，以保持组件基本上没有污染物，并被运输到组件的未被包装并组装到筒/尖端密封组合和柱塞中的组装位置。 当筒/尖端密封组合的填充和最终组装在与其组装位置分离的位置处发生时，筒/尖端密封组合被三倍重装，以使其基本上不含污染物，并被运送到填充和最终组装位置 用于填充和最终组装成预充式注射器。

    Injection system having readable information stores and method for controlling the operation thereof
    38.
    发明授权
    Injection system having readable information stores and method for controlling the operation thereof 有权
    具有可读信息存储器的注入系统和用于控制其操作的方法

    公开(公告)号：US07905861B2

    公开(公告)日：2011-03-15

    申请号：US11943735

    申请日：2007-11-21

    申请人： Edward J. Rhinehart ,  Dennis P. Hack ,  David M. Reilly ,  John F. Kalafut

    发明人： Edward J. Rhinehart ,  Dennis P. Hack ,  David M. Reilly ,  John F. Kalafut

    IPC分类号： A61M1/00

    CPC分类号： A61M5/1422 ,  A61M5/002 ,  A61M5/007 ,  A61M5/16827 ,  A61M5/16881 ,  A61M2205/128 ,  A61M2206/22

    摘要： An injection system includes a fluid delivery system, a drive mechanism, a controller and a tubing set. The fluid delivery system includes a fluid container and a pumping mechanism having an inlet in fluid connection with the fluid container and an outlet. The tubing set is adapted to be placed in removable fluid connection with the outlet of the pumping mechanism and a patient. The drive mechanism is in operative connection with the pumping mechanism to pump fluid from the fluid container. First and second information stores, such as bar codes or RFID tags, are associated with the pumping mechanism and the tubing set, respectively. The controller is in operative connection with the drive mechanism and adapted to read the first information store and the second information store to at least partly control the operation of the drive mechanism based thereon.

    摘要翻译： 注射系统包括流体递送系统，驱动机构，控制器和管道组。 流体输送系统包括流体容器和泵送机构，其具有与流体容器和出口流体连接的入口。 管组适于放置在与泵送机构的出口和患者的可移除的流体连接中。 驱动机构与泵送机构操作连接以从流体容器泵送流体。 第一和第二信息存储（例如条形码或RFID标签）分别与泵送机构和管道组相关联。 控制器与驱动机构可操作地连接，并且适于读取第一信息存储器和第二信息存储器，以至少部分地基于此控制驱动机构的操作。