公开(公告)号：US08435033B2

公开(公告)日：2013-05-07

申请号：US12839056

申请日：2010-07-19

申请人： Yossi Gross ,  Hadar Better

发明人： Yossi Gross ,  Hadar Better

IPC分类号： A61C3/00

CPC分类号： A61C1/084 ,  A61B2034/2055

摘要： Apparatus and methods are described, including at least one tool configured to be placed inside a subject's mouth. A first optically-visible marker is coupled to the tool. A second optically-visible marker is coupled to a structure inside the subject's mouth. A plurality of optical cameras are coupled to the tool, and are placed inside the subject's mouth by the tool being placed inside the subject's mouth. The cameras acquire respective images of the inside of the subject's mouth, in which the second optically-visible marker is identifiable. A plurality of optical cameras that are disposed outside the subject's mouth acquire respective images of the tool, while the tool is inside the subject's mouth, in which images the first optically-visible marker is identifiable. Other embodiments are also described.

摘要翻译： 描述了装置和方法，包括至少一个被配置为放置在受试者的嘴内的工具。 第一光学可见标记与工具耦合。 第二光学可见标记物连接到受试者口腔内的结构。 多个光学摄像机耦合到工具，并且被放置在被检者的嘴内的工具放置在被检者的嘴内。 照相机拍摄被检者口腔内部的各个图像，其中可识别第二光学可见标记物。 设置在被检者的嘴外部的多个光学照相机在工具位于被检者的嘴内时获取工具的各自的图像，其中第一光学可见标记的图像是可识别的。 还描述了其它实施例。

公开(公告)号：US08419678B2

公开(公告)日：2013-04-16

申请号：US13111313

申请日：2011-05-19

申请人： Oz Cabiri ,  Yossi Gross ,  Boris Degtiar ,  Eran Shor

发明人： Oz Cabiri ,  Yossi Gross ,  Boris Degtiar ,  Eran Shor

IPC分类号： A61M29/00

CPC分类号： A61B1/00

摘要： An apparatus for use with a biologically-compatible-fluid pressure source, the apparatus includes an elongate carrier, adapted to be inserted through a proximal opening of a body lumen, and a piston head coupled to a distal portion of the carrier. The piston head is adapted to form a pressure seal with a wall of the lumen after the carrier has been inserted into the lumen, and to be advanced distally through the body lumen in response to pressure from the fluid pressure source. The apparatus is configured to facilitate distal advancement of the piston head by facilitating passage of fluid out of the lumen from a site within the lumen distal to the piston head.

摘要翻译： 一种用于与生物相​​容的流体压力源一起使用的装置，该装置包括一个细长的载体，适于插入通过体腔的近端开口，以及活塞头，其联接到载体的远端部分。 活塞头适于在载体已经插入内腔之后与内腔的壁形成压力密封，并且响应于来自流体压力源的压力而向远侧远端推进通过体腔。 该装置被配置为通过促使流体从内腔远离活塞头的内部位置流出管腔来促进活塞头的远端前进。

公开(公告)号：US08414559B2

公开(公告)日：2013-04-09

申请号：US12437250

申请日：2009-05-07

申请人： Yossi Gross

发明人： Yossi Gross

IPC分类号： A61M31/00

CPC分类号： A61F2/04 ,  A61B5/04884 ,  A61B5/42 ,  A61B5/4238 ,  A61B5/6861 ,  A61F2002/045 ,  A61N1/0551 ,  A61N1/36007

摘要： Apparatus is provided that includes a swallowable medical treatment device, which is configured to initially assume a contracted state having a volume of less than 4 cm3. The device includes a gastric anchor, which initially assumes a contracted size, and which is configured to, upon coming in contact with a liquid, expand sufficiently to prevent passage of the anchor through a round opening having a diameter of between 1 cm and 3 cm. The device also includes a duodenal unit, which is configured to pass through the opening, and which is coupled to the gastric anchor such that the duodenal unit is held between 1 cm and 20 cm from the gastric anchor. Other embodiments are also described.

摘要翻译： 提供了包括吞咽医疗装置的装置，其被配置为最初承担体积小于4cm 3的收缩状态。 该装置包括胃锚，其最初承受缩小尺寸，并且构造成在与液体接触时被充分膨胀以防止锚通过直径为1cm至3cm的圆形开口 。 该装置还包括十二指肠单元，其被配置为穿过开口并且联接到胃锚，使得十二指肠单元保持在距离胃锚的1cm和20cm之间。 还描述了其它实施例。

公开(公告)号：US08403953B2

公开(公告)日：2013-03-26

申请号：US12509732

申请日：2009-07-27

申请人： Yossi Gross ,  Eliahu Eliachar ,  Dan Sade Hochstadter ,  Jacob Cohen ,  Hernam Weiss ,  Nir Lilach

发明人： Yossi Gross ,  Eliahu Eliachar ,  Dan Sade Hochstadter ,  Jacob Cohen ,  Hernam Weiss ,  Nir Lilach

IPC分类号： A61M29/00

CPC分类号： A61B17/12 ,  A61B5/0002 ,  A61B5/14552 ,  A61B5/4318 ,  A61B7/00 ,  A61B8/06 ,  A61B8/12 ,  A61B17/1355 ,  A61B17/42 ,  A61B2017/22067 ,  A61B2017/22069 ,  A61B2090/065 ,  A61M25/10 ,  A61M2025/1047 ,  A61M2025/1052

摘要： Apparatus is provided for use with a subject's body, vagina, vaginal fornix, uterus, and uterine artery. A fornix-engaging structure is inserted into the vagina and engages the vaginal fornix. A rod is inserted into the subject's body via the fornix-engaging structure, such that a distal end of the rod passes through vaginal tissue at a first vaginal site until the distal end of the rod is at a first extrauterine site outside of the uterine artery, but in a vicinity of a portion of the uterine artery that supplies a uterine fibroid. A rod-guide is coupled to the fornix-engaging structure, and guides the distal end of the rod to the first extrauterine site. A uterine artery compression device is disposed on the distal end of the rod. Other embodiments are also described.

摘要翻译： 设备用于受试者的身体，阴道，阴道穹窿，子宫和子宫动脉。 将阴道结合插入阴道并与阴道穹窿接合。 棒通过穹窿接合结构插入受试者的身体，使得杆的远端在第一阴道部位通过阴道组织，直到杆的远端处于子宫动脉外部的第一个宫外部位置 ，但在供应子宫肌瘤的子宫动脉的一部分附近。 杆导向件联接到穹窿接合结构，并将杆的远端引导到第一宫外部位置。 子宫动脉压迫装置设置在杆的远端。 还描述了其它实施例。

公开(公告)号：US08356994B2

公开(公告)日：2013-01-22

申请号：US13040440

申请日：2011-03-04

申请人： Hadar Better ,  Gideon Fostick ,  Yossi Gross

发明人： Hadar Better ,  Gideon Fostick ,  Yossi Gross

IPC分类号： A61C8/00

CPC分类号： A61C8/0018 ,  A61C8/0022 ,  A61C8/0092 ,  A61C19/06

摘要： A dental implant is provided that has a proximal-most part, a lateral external surface, and a distal implant portion that extends from a distal implant end along up to 50% of a longitudinal length of the implant. The implant is shaped so as to define a lumen therethrough (a) having at least one distal opening through a distal external surface of the distal implant portion, (b) having a lateral opening through the lateral external surface, and (c) not open to a proximal external surface of the implant within 2 mm of the proximal-most part of the implant. Other embodiments are also described.

摘要翻译： 提供牙科植入物，其具有近端部分，外侧外表面和远侧植入部分，其远端植入部分从远端植入物端部延伸至多达植入物纵向长度的50％。 植入物被成形为限定穿过其中的腔（a），其具有通过远侧植入部分的远侧外表面的至少一个远端开口，（b）具有通过侧向外表面的侧向开口，以及（c）不打开 到植入物的近端外部表​​面在植入物的最近部分的2mm内。 还描述了其它实施例。

公开(公告)号：US08273063B2

公开(公告)日：2012-09-25

申请号：US12227763

申请日：2007-05-30

申请人： Yossi Gross

发明人： Yossi Gross

IPC分类号： A61M37/00

CPC分类号： A61M5/1428 ,  A61M39/0208 ,  A61M39/04 ,  A61M2210/167

摘要： An implantable pump (10) is provided for pumping a drug in a patient's body (100). The pump includes a drug delivery chamber (22) configured to be filled with the drug and a drug delivery catheter (50) having a catheter lumen (58) and a distal end (56), the drug delivery catheter in fluid communication with the drug delivery chamber and configured to deliver the drug to a delivery site (102). It also includes a pushing element (44) coupled to the distal end of the catheter, and configured to push away from the catheter lumen fibrotic matter that has developed in response to the drug delivery catheter. Other embodiments are also described.

摘要翻译： 提供可植入泵（10），用于泵送患者体内的药物（100）。 泵包括配置成填充药物的药物输送室（22）和具有导管内腔（58）和远端（56）的药物输送导管（50），药物输送导管与药物流体连通 并且被配置为将药物递送到递送部位（102）。 其还包括联接到导管的远端的推动元件（44），并且构造成推动远离已经响应于药物输送导管而形成的导管腔纤维化物质。 还描述了其它实施例。

公开(公告)号：US08252050B2

公开(公告)日：2012-08-28

申请号：US12563952

申请日：2009-09-21

申请人： Francesco Maisano ,  Eran Miller ,  Oz Cabiri ,  Yaron Herman ,  Yoseph Weitzman ,  Yossi Gross ,  Tal Sheps

发明人： Francesco Maisano ,  Eran Miller ,  Oz Cabiri ,  Yaron Herman ,  Yoseph Weitzman ,  Yossi Gross ,  Tal Sheps

IPC分类号： A61F2/24

CPC分类号： A61F2/2466 ,  A61B17/0401 ,  A61B17/122 ,  A61B2017/00243 ,  A61B2017/0406 ,  A61B2017/0409 ,  A61B2017/0414 ,  A61B2017/0441 ,  A61B2017/0464 ,  A61B2017/0496 ,  A61F2/2457 ,  A61F2/2487 ,  A61F2250/0007

摘要： Apparatus is provided for adjusting at least one dimension of an implant, including a rotatable structure having first and second openings and a channel extending between the first and second openings. The channel allows passage therethrough of an elongate tool. The second end of the structure has a lower surface having one or more recesses along a circumference thereof. A mechanical element provides a protrusion that is disposed within one of the recesses of the rotatable structure during a resting state of the mechanical element, in a manner that restricts rotation of the rotatable structure. The mechanical element includes a depressible portion coupled to the protrusion disposed in communication with the second opening of the lower surface, and configured to dislodge the protrusion from within the recess in response to a force applied thereto by the elongate tool. Other applications are also described.

摘要翻译： 提供了用于调节植入物的至少一个维度的装置，包括具有第一和第二开口的可旋转结构以及在第一和第二开口之间延伸的通道。 通道允许细长工具通过。 该结构的第二端具有沿其圆周具有一个或多个凹部的下表面。 机械元件以限制可旋转结构的旋转的方式提供在机械元件的静止状态下设置在可旋转结构的一个凹部内的突起。 所述机械元件包括联接到所述突起的可压下部分，所述突起设置成与所述下表面的第二开口连通，并且被配置为响应于由所述细长工具施加到所述凹部的力而从所述凹部内移除所述突起。 还描述了其它应用。

公开(公告)号：US08152711B2

公开(公告)日：2012-04-10

申请号：US11726758

申请日：2007-03-21

申请人： Yossi Gross

发明人： Yossi Gross

IPC分类号： A61F5/00

CPC分类号： F04B43/12 ,  A61F2/26

摘要： A method is provided for controlling blood flow through a blood vessel of a subject. The method includes implanting a pump outside of the blood vessel and placing within the blood vessel an expansion element that is capable of expanding the blood vessel subsequent to compression of the blood vessel by the pump. Other embodiments are also described.

摘要翻译： 提供了一种用于控制通过受试者的血管的血流的方法。 该方法包括将泵植入血管外部并在血管内放置膨胀元件，该膨胀元件能够在通过泵压缩血管之后扩张血管。 还描述了其它实施例。

公开(公告)号：US08150526B2

公开(公告)日：2012-04-03

申请号：US12368150

申请日：2009-02-09

申请人： Yossi Gross ,  Shai Vaingast

发明人： Yossi Gross ,  Shai Vaingast

IPC分类号： A61N1/36

CPC分类号： A61N1/36046 ,  A61N1/0543 ,  A61N1/37217 ,  A61N1/3787 ,  H01L27/14621 ,  H01L27/14627 ,  H01L31/145

摘要： Apparatus is provided, including an external device, including a mount, which is placed in front of an eye of a subject. A laser is coupled to the mount and configured to emit toward the eye radiation that is outside of 380-750 nm. A partially-transparent mirror is coupled to the mount. An intraocular device is implanted entirely in the subject's eye, and includes a plurality of stimulating electrodes, and an energy receiver, which receives the radiation from the laser and generates a voltage drop in response thereto. A plurality of photosensors detect photons and generate a signal in response thereto. Driving circuitry is coupled to the energy receiver and to the photosensors, and receives the signals from the photosensors and utilizes the voltage drop to drive the electrodes to apply currents to the retina in response to the signals from the photosensors. Other embodiments are also described.

摘要翻译： 提供了一种装置，包括外部装置，其包括安装件，该安装件放置在被检体的眼睛前方。 激光器耦合到安装座并且被配置为朝向在380-750nm之外的眼睛辐射发射。 部分透明的镜子连接到安装座。 眼内装置完全植入受试者的眼睛，并且包括多个刺激电极和能量接收器，其接收来自激光器的辐射并响应于此产生电压降。 多个光电传感器检测光子并响应于此产生信号。 驱动电路耦合到能量接收器和光电传感器，并且接收来自光电传感器的信号，并且利用电压降来驱动电极，以响应于来自光电传感器的信号而向视网膜施加电流。 还描述了其它实施例。

公开(公告)号：US08135478B2

公开(公告)日：2012-03-13

申请号：US12352644

申请日：2009-01-13

申请人： Yossi Gross

发明人： Yossi Gross

IPC分类号： A61N1/18

CPC分类号： A61F7/12 ,  A61F2007/0075 ,  A61F2007/126 ,  A61N1/0432 ,  A61N1/0551 ,  A61N1/36017 ,  A61N1/3605 ,  F25B21/02

摘要： Apparatus is provided including an assembly (22) and a control unit (36). The assembly (22) includes a housing (34) configured to be applied to a nerve (20) of a subject, and at least one cathode (30) and at least one Peltier cooler (32), which are fixed to the housing (34). The control unit (36) is configured to drive the cathode (30) to apply an activating current to the nerve (20) that generates action potentials traveling in first and second directions (38 and 40) in the nerve (20), and the Peltier cooler (32) to cool the nerve (20) sufficiently to block propagation of at least a portion of the cathode-generated action potentials traveling in the second direction (40). Other embodiments are also described.

摘要翻译： 提供了包括组件（22）和控制单元（36）的设备。 组件（22）包括构造成施加到受试者的神经（20）的壳体（34）和至少一个阴极（30）和至少一个珀尔帖冷却器（32），固定到壳体 34）。 控制单元（36）被配置为驱动阴极（30）向神经（20）施加激活电流，所述神经（20）产生在神经（20）中的第一和第二方向（38和40）上行进的动作电位，并且 珀尔帖冷却器（32）以充分地冷却神经（20）以阻止至少一部分在第二方向（40）上行进的阴极产生动作电位的传播。 还描述了其它实施例。