PHOTOACTIVATED CHEMICAL BLEACHING OF DYES USING BORATES
    33.
    发明申请
    PHOTOACTIVATED CHEMICAL BLEACHING OF DYES USING BORATES 审中-公开
    使用硼酸的染料化学漂白染色

    公开(公告)号:US20160238592A1

    公开(公告)日:2016-08-18

    申请号:US14621715

    申请日:2015-02-13

    Abstract: Methods comprising the use of photoactivated chemical bleaching for detecting multiple targets in a biological sample are provided. The methods include the steps of providing a biological sample containing multiple targets, binding at least one probe to one or more target present in the sample, and observing a signal from the probe. The method further includes the steps of contacting the sample comprising the bound probe with a cationic or zwitterionic borate compound and irradiating the sample, thereby initiating a photoreaction that substantially inactivates the probe by photoactivated chemical bleaching. The method further includes the steps of binding at least one probe to one or more target present in the sample, and observing a signal from the probe. The process of binding, observing and bleaching may be iteratively repeated.

    Abstract translation: 提供了包括使用光活化化学漂白来检测生物样品中的多个靶的方法。 所述方法包括以下步骤:提供含有多个靶标的生物样品,将至少一个探针结合到样品中存在的一个或多个靶,并观察来自探针的信号。 该方法还包括使包含结合的探针的样品与阳离子或两性离子的硼酸盐化合物接触并照射样品的步骤,从而引发通过光活化的化学漂白基本上灭活探针的光反应。 该方法还包括将至少一个探针结合到样品中存在的一个或多个靶,并观察来自探针的信号的步骤。 结合,观察和漂白的过程可以迭代地重复。

    BINDER SOLUTIONS COMPRISING NANOPARTICLES FOR USE IN ADDITIVE MANUFACTURING

    公开(公告)号:US20210371619A1

    公开(公告)日:2021-12-02

    申请号:US17326692

    申请日:2021-05-21

    Abstract: A binder solution comprises greater than or equal to 0.5 wt % and less than or equal to 20 wt % of nanoparticles, a thermoplastic binder, and a solvent. The nanoparticles may comprise metallic nanoparticles comprising nickel, silver, chromium, aluminum, cobalt, iron, or combinations thereof. The nanoparticles may comprise ceramic nanoparticles, the comprising alumina, aluminum nitride, zirconia, titania, silica, silicon nitride, silicon carbide, boron nitride, or combinations thereof. A method of manufacturing a part includes depositing a layer of particulate material on a working surface, applying a binder solution into the layer of particulate material in a pattern, repeating the steps of depositing and selectively applying to form a plurality of layers of particulate material with the applied binder solution, and curing the applied binder solution in the plurality of layers of particulate material with the applied binder solution to evaporate the solvent and thereby form a green body part.

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