中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

73 records (took 0.041 seconds)

    CONTROLLED RELEASE FORMULATIONS USING INTELLIGENT POLYMERS
    31.
    发明申请
    CONTROLLED RELEASE FORMULATIONS USING INTELLIGENT POLYMERS 审中-公开
    使用智能聚合物控制释放配方

    公开(公告)号：US20080292700A1

    公开(公告)日：2008-11-27

    申请号：US12186853

    申请日：2008-08-06

    Applicant: Tien NGHIEM ,  Graham Jackson

    Inventor： Tien NGHIEM ,  Graham Jackson

    IPC: A61K9/22 ,  A61P25/08 ,  A61P25/06 ,  A61P3/04 ,  A61P25/32 ,  A61P25/36 ,  A61P25/34 ,  A61P25/18

    CPC classification number: A61K31/35 ,  A61K9/2018 ,  A61K9/2054 ,  A61K9/2846

    Abstract: A controlled release pharmaceutical composition comprises (a) topiramate or a pharmaceutically acceptable salt thereof, (b) a first intelligent polymer component; and (c) a second intelligent polymer component having opposite wettability characteristics to the first intelligent polymer component. The polymer components are effective for controlled release of the pharmaceutically active substance from the composition.

    Abstract translation: 控释药物组合物包含（a）托吡酯或其药学上可接受的盐，（b）第一智能聚合物组分; 和（c）具有与第一智能聚合物组分相反润湿特性的第二智能聚合物组分。 聚合物组分对于从组合物中控制释放药物活性物质是有效的。

    Fuel oil composition
    35.
    发明申请
    Fuel oil composition 有权
    燃油组成

    公开(公告)号：US20050000151A1

    公开(公告)日：2005-01-06

    申请号：US10856724

    申请日：2004-05-28

    Applicant: Graham Jackson

    Inventor： Graham Jackson

    IPC: C10L1/192 ,  C08G8/00 ,  C08G61/02 ,  C10L1/02 ,  C10L1/14 ,  C10L1/16 ,  C10L1/18 ,  C10L1/198 ,  C10L1/22 ,  C10L10/14

    CPC classification number: C10L1/1981 ,  C08G61/02 ,  C10L1/143 ,  C10L1/1658 ,  C10L1/1973 ,  C10L1/1985 ,  C10L1/2222 ,  C10L1/224

    Abstract: A fuel oil composition comprising a fuel oil and 0.1 to 10,000 ppm of a polymeric condensation product which is formed by the reaction of an aliphatic aldehyde or ketone, or a reactive equivalent, with either (i) a straight or branched chain C1-C7 alkyl ester of p-hydroxybenzoic acid, or with (ii) a branched chain C8-C16 alkyl ester of p-hydroxybenzoic acid, or with (iii) a mixture of long chain C8-C18 alkyl esters of p-hydroxybenzoic acid, at least one of said alkyls being branched. The polymeric condensation product improves the cold flow characteristics of the fuel oil.

    Abstract translation: 一种燃料油组合物，其包含燃料油和0.1至10,000ppm的聚合缩合产物，其通过脂族醛或酮或反应性当量与（i）直链或支链C 1 -C 7烷基 对 - 羟基苯甲酸的酯或与（ii）对羟基苯甲酸的支链C 8 -C 16烷基酯或（iii）对羟基苯甲酸的长链C8-C18烷基酯的混合物，至少一种 的所述烷基是支链的。 聚合物缩合产物改善燃料油的冷流特性。

    Process for the chlorination of sugars
    38.
    发明授权
    Process for the chlorination of sugars 失效
    糖的氯化处理

    公开(公告)号：US4977254A

    公开(公告)日：1990-12-11

    申请号：US388657

    申请日：1989-08-02

    Applicant: Nigel J. Homer ,  Graham Jackson ,  George H. Sankey ,  Philip J. Simpson

    Inventor： Nigel J. Homer ,  Graham Jackson ,  George H. Sankey ,  Philip J. Simpson

    IPC: C07B61/00 ,  C07H5/02 ,  C07H11/00 ,  C07H13/04

    CPC classification number: C07H5/02 ,  C07H11/00 ,  C07H13/04

    Abstract: Sugars and partly protected sugar derivatives are chlorinated by reaction of unprotected hydroxyl groups with thionyl chloride to form a persulphite followed by decomposition of the sulphite groups to form chlorosulphites, displacement of the chlorosulphite groups and insertion of chlorine atoms at one or more positions, characterised in that formation and displacement of the chlorosulphite groups and insertion of chlorine atoms is effected by reaction with thionyl chloride in an inert solvent in the presence of a quaternary salt of the general formula:N.sup.+ R.sup.1 R.sup.2 R.sup.3 R.sup.4 Cl.sup.- (I)wherein R.sup.1, R.sup.2 and R.sup.3, which may be the same or different, each represent a lower alkyl group, and R.sup.4 represents a hydrocarbon group with at least seven carbon atoms; and, when the sugar or partly protected sugar derivative has more than three unprotected hydroxyl groups, the process comprises the following stages:(a) reaction of the sugar or partly protected sugar derivative with thionyl chloride in the presence of pyridine to form a persulphite;(b) isolation of the polysulphite to remove free pyridine; and(c) reaction of the isolated polysulphite with thionyl chloride in an inert solvent or suspension medium in the presence of a quaternary salt of the general formula (I).

    Sucralose co-crystallized with a nitrogenous base
    39.
    发明授权
    Sucralose co-crystallized with a nitrogenous base 失效
    三氯蔗糖与含氮碱共结晶

    公开(公告)号：US4751294A

    公开(公告)日：1988-06-14

    申请号：US818720

    申请日：1986-01-14

    Applicant: Graham Jackson

    Inventor： Graham Jackson

    IPC: A23L27/30 ,  C07H5/02 ,  C07H3/04 ,  A61K9/68 ,  C07H15/00

    CPC classification number: C07H5/02 ,  A23L27/37

    Abstract: Sucralose (4-chloro-4-deoxy-.alpha.-D-galactopyranosyl 1,6-dichloro-1,6-dideoxy-.beta.-D-fructofuranoside) is thermally stabilized by co-crystallization with a nitrogenous base, for example niacinamide or an amino acid.

    Abstract translation: 三氯蔗糖（4-氯-4-脱氧-α-D-吡喃半乳糖基1,6-二氯-1,6-二脱氧-β-D-呋喃果糖苷）通过与含氮碱例如烟酰胺或 氨基酸。

    Compositions and methods for prion decontamination
    40.
    发明授权
    Compositions and methods for prion decontamination 有权
    朊蛋白去污的组成和方法

    公开(公告)号：US08431526B2

    公开(公告)日：2013-04-30

    申请号：US13221417

    申请日：2011-08-30

    Applicant: Vincent Brian Croud ,  Graham Jackson ,  John Collinge

    Inventor： Vincent Brian Croud ,  Graham Jackson ,  John Collinge

    IPC: C07K14/00

    CPC classification number: A61L2/16 ,  A01N37/16 ,  A23L3/3499 ,  A23L3/3508 ,  A23L3/3571 ,  A61L2/186 ,  A61L2202/24 ,  C11D3/386 ,  C11D3/3947 ,  C11D3/48 ,  C11D11/0041 ,  A01N2300/00 ,  A01N25/30 ,  A01N37/46 ,  A01N61/00 ,  A01N63/00 ,  A01N63/02 ,  A01N63/04 ,  A01N65/00

    Abstract: The invention relates to compositions and methods for prion degradation, decontamination or disinfection. The composition comprises an oxidizing agent, one or more proteases and a surfactant such as an ionic surfactant/detergent. The method comprises contacting a prion contaminated entity with a prion-degrading composition comprising an effective amount of an oxidizing agent, an effective amount of at least one protease, and an effective amount of a surfactant. The components of the composition may be contacted with a prion-contaminated entity sequentially or simultaneously using an aqueous composition. Typically at least two different proteases are used for optimal efficacy. Preferably the oxidizing agent comprises peracetyl ions or a source thereof. The invention also relates to kits comprising the various reagents.

    Abstract translation: 本发明涉及朊病毒降解，去污或消毒的组合物和方法。 组合物包含氧化剂，一种或多种蛋白酶和表面活性剂如离子表面活性剂/洗涤剂。 该方法包括使朊病毒污染的实体与包含有效量的氧化剂，有效量的至少一种蛋白酶和有效量的表面活性剂的朊病毒降解组合物接触。 组合物的组分可以使用水性组合物依次或同时与朊病毒污染的实体接触。 通常使用至少两种不同的蛋白酶来获得最佳疗效。 优选地，氧化剂包括全乙酰离子或其源。 本发明还涉及包含各种试剂的试剂盒。

Patent Agency Ranking