公开(公告)号：US20100283087A1

公开(公告)日：2010-11-11

申请号：US12840597

申请日：2010-07-21

申请人： Mirko Lehmann ,  Ingo Freund

发明人： Mirko Lehmann ,  Ingo Freund

IPC分类号： H01L29/66

CPC分类号： G01N27/4148

摘要： An electric component comprising a sensor and/or actuator chip with a substrate on which a passivating layer and a sensor and/or actuator structure consisting of an active surface area is arranged. The chip is surrounded by an encapsulation having an opening which forms an access to the at least one active surface area. A layer stack is arranged on the substrate, said stack of layers comprising from the passivating layer to the substrate at least one first strip conductor layer, a first electric insulating layer, a second strip conductor layer and a second electric insulating layer. The first conductor strip layer is fully arranged outside the area of the chip covered by the opening. At least one conductor strip of the second conductor strip layer is connected to the sensor and/or actuator structure.

摘要翻译： 一种电气部件，包括具有衬底的传感器和/或致动器芯片，其上布置有钝化层和由有源表面区域组成的传感器和/或致动器结构。 芯片由具有开口的封装围绕，该开口形成对至少一个有源表面区域的访问。 层叠在衬底上，层叠层包括至少一个第一带状导体层，第一电绝缘层，第二带状导体层和第二电绝缘层，从钝化层到衬底。 第一导体带层完全布置在由开口覆盖的芯片的区域的外部。 第二导体带层的至少一个导体条连接到传感器和/或致动器结构。

公开(公告)号：US20090029403A1

公开(公告)日：2009-01-29

申请号：US12078794

申请日：2008-04-04

申请人： Maximilian Fleischer ,  Mirko Lehmann ,  Elfriede Simon

发明人： Maximilian Fleischer ,  Mirko Lehmann ,  Elfriede Simon

IPC分类号： C12Q1/02 ,  C12M1/34

CPC分类号： C12Q1/025 ,  G01N27/4141 ,  G01N2520/00

摘要： A sensor for detecting a gas mixture which substantially comprises air and contains one or a plurality of gases that exhibit a disadvantageous effect on living organisms, comprising: a sensor chip composed of silicon for reading out at least one signal which is generated at a sensitive substance given the presence of one or a plurality of target gases in the measurement gas, a sensitive substance applied on the sensor chip, comprising living cells, which respond to target gas, a signal processing unit for evaluating the signals of the Si chip.

摘要翻译： 一种用于检测气体混合物的传感器，其基本上包括空气并且包含对活生物体具有不利影响的一种或多种气体，包括：由硅组成的传感器芯片，用于读出在敏感物质处产生的至少一种信号 考虑到测量气体中存在一种或多种目标气体，施加在传感器芯片上的敏感物质包括响应于目标气体的活细胞，用于评估Si芯片的信号的信号处理单元。

公开(公告)号：US07470962B2

公开(公告)日：2008-12-30

申请号：US10591413

申请日：2005-03-01

申请人： Werner Baumann ,  Mirko Lehmann ,  Ingo Freund ,  Hans-Jurgen Gahle

发明人： Werner Baumann ,  Mirko Lehmann ,  Ingo Freund ,  Hans-Jurgen Gahle

IPC分类号： H01L31/00

CPC分类号： G01N33/48728 ,  G01N27/4145

摘要： The invention relates to a device for measuring living cells or similar biocomponents comprising a field effect transistor which is provided with a source, a drain and a channel area placed on a substrate. Said channel area connects said source and drain and is provided with a gate-electrode mounted thereon. The gate electrode has at least two laterally disposed parallel electrode areas which are perpendicular to a direction in which the channel area connects the source to the drain in such a way that they are distant and electrically insulated from each other.

摘要翻译： 本发明涉及用于测量活细胞或类似生物组件的装置，其包括场效应晶体管，该场效应晶体管设置有放置在基板上的源极，漏极和沟道区域。 所述通道区域连接所述源极和漏极，并且设置有安装在其上的栅电极。 栅电极具有至少两个横向设置的平行电极区域，其垂直于沟道区域将源极连接到漏极的方向，使得它们彼此远离并且电绝缘。

公开(公告)号：US07462326B2

公开(公告)日：2008-12-09

申请号：US10528954

申请日：2003-09-26

申请人： Mirko Lehmann ,  Claas Müller ,  Holger Klapproth ,  Ingo Freund

发明人： Mirko Lehmann ,  Claas Müller ,  Holger Klapproth ,  Ingo Freund

IPC分类号： G01N21/76 ,  G01N21/00 ,  G01N33/543 ,  G01N21/41 ,  G02B6/12 ,  G02B6/00 ,  G02B6/10 ,  G01B9/02 ,  C12M1/34

CPC分类号： G01N21/648 ,  G01N21/552 ,  G01N21/6428 ,  G01N21/6454 ,  G01N33/54373

摘要： Disclosed is a device for detecting at least one ligand contained in a sample that is to be analyzed. Said device comprises an optical waveguide, on the surface of which at least one ligand-specific receptor is directly or indirectly immobilized. The ligand bonds to said receptor during contact therewith. The inventive device comprises at least one optical source of radiation for injecting excitation radiation into the waveguide, the radiation being used for exciting emission of luminescence radiation in accordance with the bonding of the ligand to the receptor. At least one radiation receiver is integrated into the semiconductor substrate of a semiconductor chip so as to detect the luminescence radiation. The waveguide is integrated in a monolithic manner into the semiconductor substrate or is applied thereupon as a wave-guiding layer.

摘要翻译： 公开了一种用于检测待分析样品中所含的至少一种配体的装置。 所述装置包括光波导，其表面上直接或间接固定至少一种配体特异性受体。 配体在与其接触时与所述受体结合。 本发明的装置包括至少一个用于将激发辐射注入到波导中的辐射光源，所述辐射用于根据配体与受体的结合激发发射辐射。 至少一个辐射接收器被集成到半导体芯片的半导体衬底中，以便检测发光辐射。 波导以单片方式集成到半导体衬底中或作为波导层施加在其上。

公开(公告)号：US20080237654A1

公开(公告)日：2008-10-02

申请号：US10592848

申请日：2005-03-04

申请人： Mirko Lehmann ,  Heinz-Peter Frerichs ,  Christoph Wilbertz

发明人： Mirko Lehmann ,  Heinz-Peter Frerichs ,  Christoph Wilbertz

IPC分类号： H01L27/088 ,  G01N7/00

CPC分类号： G01N27/4143 ,  H01L2924/0002 ,  H01L2924/00

摘要： A device for detecting a gas or gas mixture having at least one first gas sensor designed as an SGFET and at least—one second, additional gas sensor designed as a Lundström-FET. The gas sensors are connected to a processing device designed to analyze the measurement signals from both types of gas sensors in order to detect the gas or gas mixture.

摘要翻译： 一种用于检测气体或气体混合物的装置，其具有设计为SGFET的至少一个第一气体传感器和设计为Lundström-FET的至少一个第二附加气体传感器。 气体传感器连接到设计用于分析来自两种类型的气体传感器的测量信号的处理装置，以便检测气体或气体混合物。

公开(公告)号：US20080220541A1

公开(公告)日：2008-09-11

申请号：US12152315

申请日：2008-05-14

申请人： Bernhard Wolf ,  Hans-Jurgen Gahle ,  Gunter Igel ,  Werner Baumann ,  Ralf Ehret ,  Mirko Lehmann

发明人： Bernhard Wolf ,  Hans-Jurgen Gahle ,  Gunter Igel ,  Werner Baumann ,  Ralf Ehret ,  Mirko Lehmann

IPC分类号： H01L21/00 ,  G01N33/53 ,  G01N33/566 ,  C12Q1/70 ,  G01N33/543

CPC分类号： H01L22/24 ,  G01B11/30 ,  G01N21/94

摘要： A process for structuring a surface layer of an object includes applying bio-components to the surface of the object that carry away surface material. The bio-components are contained in at least one of a nutrient and osmotic protective medium. The at least one of a nutrient and osmotic protective medium having the bio-components contained therein is removed after the surface material is carried away from the object surface.

摘要翻译： 用于构造物体的表面层的方法包括将生物组分应用于携带表面材料的物体的表面。 生物成分包含在营养和渗透保护介质中的至少一种中。 在将表面材料从物体表面带走之后，除去其中含有生物成分的营养物和渗透保护介质中的至少一种。

公开(公告)号：US20080145856A1

公开(公告)日：2008-06-19

申请号：US11951779

申请日：2007-12-06

申请人： Mirko Lehmann

发明人： Mirko Lehmann

IPC分类号： C12Q1/68 ,  G01N21/76 ,  B01J19/00

CPC分类号： G01N21/6456 ,  G01N21/6408 ,  G01N21/6428 ,  G01N21/6486 ,  G01N2021/6441

摘要： In a method for detecting at least one ligand that is suspected to be contained in the fluid that is being tested, at least one marker that is suitable for binding to the ligand is placed in the fluid. At least one measured value for the diffusion rate of the marker in the fluid is acquired. In addition, a reference value range for the diffusion rate exhibited by a complex consisting of at least the ligand and the marker that is bound to it in the fluid is provided. The measured value is compared with the reference value range and the presence of the ligand in the fluid is deduced depending on the results of this comparison.

摘要翻译： 在用于检测疑似包含在待测试流体中的至少一种配体的方法中，适合于结合配体的至少一种标记被置于流体中。 获取流体中标记物的扩散速率的至少一个测量值。 此外，提供了由至少配体和在流体中与其结合的标记物组成的络合物所表现的扩散速率的参考值范围。 将测量值与参考值范围进行比较，并根据该比较的结果推导出流体中配体的存在。

公开(公告)号：US20080028477A1

公开(公告)日：2008-01-31

申请号：US11579213

申请日：2005-02-02

申请人： Mirko Lehmann ,  Ulrich Sieben

发明人： Mirko Lehmann ,  Ulrich Sieben

IPC分类号： G06F1/26 ,  G08B29/16

CPC分类号： H01M8/02 ,  G06K19/0702 ,  G06K19/073 ,  G06K19/07381 ,  H01L23/576 ,  H01L2924/0002 ,  H01M8/04559 ,  H01M8/04917 ,  H01M8/04947 ,  H01M8/2475 ,  H01M2250/00 ,  H01M2250/30 ,  Y02B90/18 ,  H01L2924/00

摘要： A chip includes a memory that stores confidential data, a power supply device to apply a voltage and/or or a current, and an interface to transfer the data from and/or to another device. To secure the data in the memory, the power supply device is an integrated component of the chip. The power supply device is equipped with a limited, non-replenishable fuel reservoir so that data can be maintained in the memory over a limited service life. In other embodiments, voltage provided by the power supply device can also be employed actively to delete data in the memory in the event of unauthorized access to the chip.

摘要翻译： 芯片包括存储秘密数据的存储器，用于施加电压和/或电流的电源装置，以及将数据从和/或传送到另一装置的接口。 为了保护存储器中的数据，电源设备是芯片的集成组件。 电源设备配备有限的，不可补充的燃料储存器，以便数据可在有限的使用寿命内保持在存储器中。 在其他实施例中，在未经授权的访问芯片的情况下，还可以主动地采用由电源装置提供的电压来删除存储器中的数据。

公开(公告)号：US20070243637A1

公开(公告)日：2007-10-18

申请号：US11784768

申请日：2007-04-09

申请人： Sonja Mohry ,  Holger Klapproth ,  Mirko Lehmann ,  Ingo Freund

发明人： Sonja Mohry ,  Holger Klapproth ,  Mirko Lehmann ,  Ingo Freund

IPC分类号： G01N33/543 ,  C12M3/00

CPC分类号： G01N33/558 ,  G01N33/54306

摘要： In a process for determining the concentrations of ligands (9, 10) in a sample to be analyzed, ligands (9) of a first ligand type are bond-specific for receptors (6) of a first receptor type, and ligands (10) of a second ligand type are bond-specific for receptors (8) of a second receptor type. A first receptor (6) of the first receptor type is immobilized at least one first test site (5), and a second receptor (8) of the second receptor type is immobilized at a second test site (7) on a substrate (23). A third receptor (11) of the second receptor type is mixed with the sample in such a way that it is present in a specified concentration in the mixture that is obtained in this manner. The mixture is caused to contact the substrate in such a way that at least one ligand (9) of the first ligand type can bind to the first receptor (6) and ligands (10) of the second ligand type can bind to the second receptor (8) and to the third receptor (11). Thereupon components of the mixture that are not bound to an immobilized receptor (6, 8) are removed from the substrate. Thereupon a first measurement signal that is dependent on the concentration of the ligand (9) bound to the first receptor (6) and a second measurement signal that is dependent on the concentration of the ligand (10) bound to the second receptor (8) are generated. With the aid of the first measurement signal the concentration of the ligand (9) of the first ligand type in the sample is determined and, with the aid of the second measurement signal and of the concentration of the third receptor (11) in the mixture, the concentration of the ligands (10) of the second ligand type in the sample is determined.

摘要翻译： 在用于测定待分析样品中配体（9,10）的浓度的方法中，第一配体类型的配体（9）对于第一受体类型的受体（6）是键特异性的，而配体（10） 第二种配体类型是第二受体类型的受体（8）的键特异性。 将第一受体类型的第一受体（6）固定在至少一个第一测试位点（5）上，并且将第二受体类型的第二受体（8）固定在基底（23）上的第二测试位点（7） ）。 将第二受体类型的第三受体（11）与样品混合，使得其以以这种方式获得的混合物中以特定浓度存在。 使混合物以这样的方式接触底物，使得第一配体型的至少一种配体（9）可以结合第一受体（6），并且第二配体型的配体（10）可以结合第二受体 （8）和第三受体（11）。 因此，从底物中除去不与固定化受体（6,8）结合的混合物的组分。 因此，依赖于与第一受体（6）结合的配体（9）的浓度的第一测量信号和取决于与第二受体（8）结合的配体（10）的浓度的第二测量信号， 被生成。 借助于第一测量信号，测定样品中第一配体类型的配体（9）的浓度，借助于第二测量信号和混合物中第三受体（11）的浓度 测定样品中第二配体类型的配体（10）的浓度。

公开(公告)号：US20050244701A1

公开(公告)日：2005-11-03

申请号：US11074594

申请日：2005-03-08

申请人： Gilbert Erdler ,  Mirko Lehmann ,  Class Muller

发明人： Gilbert Erdler ,  Mirko Lehmann ,  Class Muller

IPC分类号： H01M8/16 ,  H01M8/18 ,  H01M14/00 ,  H01M8/04 ,  H01M8/10

CPC分类号： H01M8/16 ,  H01M8/186 ,  H01M14/005 ,  Y02E60/527 ,  Y02E60/528

摘要： This invention relates to a fuel cell system that has a fuel cell and a fuel infeed device. The fuel cell is equipped with a first electrode and a second electrode, one of which is designed as a cathode and the other as an anode, a layer with catalytic activity permeable at least to protons between the electrodes, a fuel supply device for the infeed of a fuel, and a reactant supply device for the infeed of a reactant (O2) that reacts with protons from the fuel to produce current, with the fuel supply device and the reactant supply device located directly on the face of one of the electrodes. The fuel infeed device is connected to the fuel supply device for feeding in the fuel, with the fuel supply device being designed as one of the electrodes. The fuel supply device is also designed as a storage device for the fuel. In addition to the capability of autonomously supplying an electrical circuit with such a fuel cell system as a micro energy supply device, one embodiment is especially preferred in which the fuel cell system as a fuel infeed device also has an integrated electrolysis unit for regenerating

摘要翻译： 本发明涉及具有燃料电池和燃料供给装置的燃料电池系统。 燃料电池配备有第一电极和第二电极，其中一个被设计为阴极，另一个被设计为阳极，催化活性至少可以渗透至电极之间的质子的层，用于进料的燃料供应装置 的燃料，以及用于与燃料的质子反应产生电流的反应物（O 2 2）的进料的反应物供应装置，燃料供应装置和反应物供应装置直接位于 一个电极的面。 燃料供给装置连接到燃料供给装置，用于供给燃料，燃料供给装置被设计为电极之一。 燃料供应装置还被设计为用于燃料的储存装置。 作为微能量供给装置的这种燃料电池系统的电路自主供电的一个实施例，作为燃料供给装置的燃料电池系统也具有一体化的电解装置，