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    Catheter devices and drainage systems for delivering therapeutic agents
    31.
    发明授权
    Catheter devices and drainage systems for delivering therapeutic agents 有权
    用于输送治疗剂的导管装置和排水系统

    公开(公告)号：US08998854B2

    公开(公告)日：2015-04-07

    申请号：US12695899

    申请日：2010-01-28

    申请人： William F. McKay

    发明人： William F. McKay

    IPC分类号： A61M5/178 ,  A61M27/00 ,  A61M25/00 ,  A61M1/00

    CPC分类号： A61M27/00 ,  A61M1/0084 ,  A61M25/0026 ,  A61M25/003 ,  A61M25/007 ,  A61M2025/0031 ,  A61M2025/0036 ,  A61M2025/004

    摘要： A catheter for drainage of a wound and delivery of a therapeutic agent at or near the wound of a patient is provided. The catheter comprises: a proximal end configured to receive the therapeutic agent and permit passage of bodily fluid, the proximal end configured to be coupled to a drainage tube and/or a therapeutic agent delivery device; a distal end for insertion at or near the wound; and a body disposed between the proximal end and distal end of the catheter and configured to receive the therapeutic agent from the proximal end of the catheter, the body having a first set of holes configured to allow passage of the therapeutic agent from the proximal end to a site at or near the wound and the body having a second set of holes configured to allow drainage of bodily fluid from the wound into the catheter.

    摘要翻译： 提供了用于在患者的伤口处或伤口附近引导伤口和递送治疗剂的导管。 所述导管包括：近端构造成容纳所述治疗剂并允许体液通过，所述近端构造成联接到排液管和/或治疗剂递送装置; 用于插入伤口处或附近的远端; 以及设置在所述导管的所述近端和远端之间并且构造成从所述导管的近端接收所述治疗剂的主体，所述主体具有第一组孔，所述第一组孔构造成允许所述治疗剂从所述近端通过至 伤口处或附近的部位和身体具有第二组孔，其被配置为允许体液从伤口排出到导管中。

    Bone delivery systems including holding and filling devices and methods
    32.
    发明授权
    Bone delivery systems including holding and filling devices and methods 有权
    骨输送系统，包括保持和灌装装置和方法

    公开(公告)号：US08926622B2

    公开(公告)日：2015-01-06

    申请号：US13438590

    申请日：2012-04-03

    申请人： William F. McKay

    发明人： William F. McKay

    IPC分类号： A61B17/58 ,  A61B17/60 ,  A61F2/00

    CPC分类号： A61F2/2846 ,  A61F2002/2835 ,  A61F2002/30462 ,  A61F2002/30586 ,  A61F2002/30588 ,  A61F2002/30729 ,  A61F2210/0004

    摘要： A delivery system comprising a biodegradable single or multi compartment covering is provided. The covering can be a mesh bag including a pre-attached detachable holding member surrounding the opening of at least one compartment and a pre-attached removable filling member configured to fit within the opening of the at least one compartment. The opening of the bag can include a closing member. The pre-attached detachable holding member can be a collar including finger grips and is used to hold the bag in one position while filling it. In some embodiments, the pre-attached detachable filling member can be a funnel for loading the mesh bag with bone graft material. Once the covering is filled, the holding member and filling member can be removed and the covering is closed with a closing member such as a drawstring. A method of treatment utilizing the delivery system is also provided.

    摘要翻译： 提供包括可生物降解的单室或多隔室覆盖物的递送系统。 覆盖物可以是网袋，其包括围绕至少一个隔室的开口的预先附接的可拆卸保持构件和构造成装配在至少一个隔室的开口内的预先附接的可移除填充构件。 袋的开口可以包括封闭构件。 预先安装的可拆卸的保持构件可以是包括手指的衣领，并且用于在将袋子填充在一个位置时将其保持在一个位置。 在一些实施例中，预先附接的可拆卸填充构件可以是用于使用骨移植材料装载网袋的漏斗。 一旦覆盖物被填充，就可以移除保持构件和填充构件，并且用诸如束带的关闭构件封闭覆盖物。 还提供了利用递送系统的治疗方法。

    INTERBODY BONE IMPLANT DEVICE
    37.
    发明申请
    INTERBODY BONE IMPLANT DEVICE 有权

    公开(公告)号：US20130274890A1

    公开(公告)日：2013-10-17

    申请号：US13448647

    申请日：2012-04-17

    申请人： William F. McKay

    发明人： William F. McKay

    IPC分类号： A61F2/28

    CPC分类号： A61F2/4455 ,  A61F2/4611 ,  A61F2002/2835 ,  A61F2002/30059 ,  A61F2002/30448 ,  A61F2002/30784 ,  A61F2002/30904 ,  A61L27/18 ,  A61L2430/02 ,  C08L71/00

    摘要： A composite interbody bone implant device is provided including a body having a non-bone composition, such as a polymer, formed into a shape and including one or more cavities. An osteoinductive material, such as bone allograft tissue, may be retained in the one or more cavities of the body. The body is formable via injection molding and/or machining into a shape and size adapted for implantation at a surgical site. The dimensions of the body include a length, a width and a thickness, and the thickness of the body may be less than at least one of the length and width.

    摘要翻译： 提供了一种复合体间骨植入装置，其包括形成为包括一个或多个空腔的形状的非骨组合物如聚合物的主体。 诸如骨同种异体移植组织的骨诱导材料可以保留在身体的一个或多个腔中。 身体可以通过注射成型和/或加工形成适于植入手术部位的形状和尺寸。 身体的尺寸包括长度，宽度和厚度，并且身体的厚度可以小于长度和宽度中的至少一个。

    MEDICAL DEVICES AND METHODS COMPRISING AN ADHESIVE SHEET CONTAINING A DRUG DEPOT
    38.
    发明申请
    MEDICAL DEVICES AND METHODS COMPRISING AN ADHESIVE SHEET CONTAINING A DRUG DEPOT 有权

    公开(公告)号：US20130018321A1

    公开(公告)日：2013-01-17

    申请号：US13180685

    申请日：2011-07-12

    申请人： William F. McKay

    发明人： William F. McKay

    IPC分类号： A61M5/00

    CPC分类号： A61K47/34 ,  A61K9/0024 ,  A61K31/58

    摘要： Improved medical devices and methods are provided that are implantable at or near a target tissue site beneath the skin of a patient, the medical device comprises an adhesive sheet having a region configured to receive a drug depot, the drug depot disposed within the region of the adhesive sheet and the drug depot having at least one surface configured to release a therapeutically effective amount of the drug over a period of at least one day, wherein the adhesive sheet limits movement of the medical device at or near the target tissue site. In some embodiments, the medical device provided can include an effective amount of at least one analgesic and/or at least one anti-inflammatory agent at or near a target site, and can reduce, prevent or treat inflammation and/or pain, particularly postoperative pain or orthopedic degenerative pathology pain.

    MEDICAL DEVICES AND METHODS COMPRISING AN ADHESIVE MATERIAL
    39.
    发明申请
    MEDICAL DEVICES AND METHODS COMPRISING AN ADHESIVE MATERIAL 有权
    医疗装置和包含粘合材料的方法

    公开(公告)号：US20130018320A1

    公开(公告)日：2013-01-17

    申请号：US13180676

    申请日：2011-07-12

    申请人： William F. McKay

    发明人： William F. McKay

    IPC分类号： A61M5/00

    CPC分类号： A61M37/0069 ,  A61K9/0024 ,  A61M2025/0246 ,  A61M2025/0253

    摘要： Improved medical devices and methods are provided that are implantable at or near a target tissue site beneath the skin of a patient, the medical device comprising an adhesive sheet having a region configured to receive a solid or semi-solid drug depot, the drug depot disposed within the region of the adhesive sheet, the drug depot having at least one surface configured to release a therapeutically effective amount of the drug over a period of at least one day, wherein the adhesive sheet limits movement of the medical device at or near the target tissue site. In some embodiments, the medical device provided can include an effective amount of at least one analgesic and/or at least one anti-inflammatory agent at or near a target site, and can reduce, prevent or treat inflammation and/or pain, such as postoperative pain or orthopedic degenerative pathology pain.

    摘要翻译： 提供了改进的医疗装置和方法，其可植入在患者皮肤下方的靶组织部位处或附近，该医疗装置包括具有构造成接收固体或半固体药物贮库的区域的粘合片， 在粘合片区域内，药物贮库具有至少一个表面，其被配置为在至少一天的时间段内释放治疗有效量的药物，其中所述粘合片限制所述医疗装置在所述靶或靶附近的移动 组织部位。 在一些实施方案中，所提供的医疗装置可包括有效量的至少一种止痛剂和/或至少一种抗炎剂，其在靶位点附近或其附近，并且可以减少，预防或治疗炎症和/或疼痛，例如 术后疼痛或骨科退行性病理疼痛。