公开(公告)号：US20200315504A1

公开(公告)日：2020-10-08

申请号：US16375752

申请日：2019-04-04

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Chi-En Lin ,  David Probst ,  Mohsen Askarinya ,  Akhil Srinivasan ,  Melissa Tsang ,  Michael E. Miller ,  Parisa Kamgar

IPC: A61B5/145 ,  A61B5/1486 ,  C12Q1/54 ,  G01N27/327 ,  A61B5/00

Abstract: The invention includes method and materials designed to measure the material properties (e.g. thickness) of layers of material in a sensor using non-Faradaic EIS (Electrochemical Impedance Spectroscopy) methods. The methods are non-destructive, very sensitive and rapid. Typically in these methods, an AC voltage is applied to the desired material layer while the output current and therefore impedance is measured. This voltage can be applied in multiple frequencies in sweep mode in order to detect both the material and, for example, the thickness of the target material. In this way, EIS allows the characterization of properties of various layers of material disposed in devices such as electrochemical glucose sensors.

公开(公告)号：US10420508B2

公开(公告)日：2019-09-24

申请号：US15357925

申请日：2016-11-21

Applicant: Medtronic MiniMed, Inc.

Inventor： David C. Antonio ,  Eric Allan Larson ,  Jose J. Ruelas ,  Akhil Srinivasan

IPC: A61B5/145 ,  A61B5/00 ,  A61M5/172 ,  A61M5/158 ,  A61B5/1486 ,  A61B5/1473 ,  A61B5/15

Abstract: This disclosure generally relates to medical devices that include a sensor transmitter assembly that includes a sensor assembly including a sensor module where a first sensor including a first sensor head having at least one first sensor contact pad is combined with a second sensor including a second sensor head having at least one second sensor contact pad. The sensor transmitter assembly also includes a transmitter assembly positioned on a top of the sensor assembly to form a single unit, the transmitter assembly having at least one transmitter contact disposed on a base of the transmitter assembly, where the first sensor contact pad(s) and the second sensor form a connection path with the transmitter contact(s).

公开(公告)号：US11938303B2

公开(公告)日：2024-03-26

申请号：US18066212

申请日：2022-12-14

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Steven C. Jacks ,  Peter Ajemba ,  Akhil Srinivasan ,  Jacob E. Pananen ,  Sarkis Aroyan ,  Pablo Vazquez ,  Tri T. Dang ,  Ashley N. Sullivan ,  Raghavendhar Gautham

IPC: A61B5/1495 ,  A61B5/145 ,  A61M5/142 ,  A61M5/172 ,  A61B5/00 ,  G16H20/17

CPC classification number: A61M5/1723 ,  A61B5/14532 ,  A61B5/1495 ,  A61M5/14244 ,  A61B5/4839 ,  A61B2560/0223 ,  A61B2560/0238 ,  A61M2005/14208 ,  G16H20/17

Abstract: Techniques disclosed herein relate to determining a calibrated measurement value indicative of a physiological condition of a patient using sensor calibration data and a performance model. In some embodiments, the techniques involve obtaining one or more electrical signals from a sensing element of a sensing arrangement, where the one or more electrical signals are influenced by a physiological condition in a body of a patient. The techniques also involve obtaining calibration data associated with the sensing element from a data storage element of the sensing arrangement, converting the one or more electrical signals into one or more calibrated measurement parameters using the calibration data, obtaining a performance model associated with the sensing element, obtaining personal data associated with the patient, and determining, using the performance model and based on the personal data and the one or more calibrated measurement parameters, a calibrated output value indicative of the physiological condition.

公开(公告)号：US11793930B2

公开(公告)日：2023-10-24

申请号：US16893141

申请日：2020-06-04

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Chia-Hung Chiu ,  Rebecca K. Gottlieb ,  Ellis Garai ,  Akhil Srinivasan ,  Andrea Varsavsky ,  Adam S. Trock ,  Ashwin K. Rao ,  Hsifu Wang ,  Daniel E. Pesantez ,  Isabella Ella Miya ,  Xinrui Zhang ,  Guruguhan Meenakshisundaram

IPC: A61M5/142 ,  A61M39/10 ,  A61M5/172 ,  A61M5/162 ,  A61M5/168 ,  A61M37/00

CPC classification number: A61M5/14248 ,  A61M5/162 ,  A61M5/16831 ,  A61M5/1723 ,  A61M37/0015 ,  A61M39/10 ,  A61M2005/14252 ,  A61M2037/0023 ,  A61M2205/50 ,  A61M2205/8206 ,  A61M2205/8243 ,  A61M2230/201

Abstract: A fluid infusion system includes a housing configured to be adhesively coupled to an anatomy of a user, and a tube configured to extend from the housing for insertion into the anatomy of the user. The tube includes a plurality of conduits defined within the tube. The plurality of conduits include a fluid delivery conduit configured to facilitate a fluidic connection between a fluid source and the anatomy of the user, and one or more conduits configured to accommodate a plurality of electrodes for determining a physiological characteristic of the user.

公开(公告)号：US20230241315A1

公开(公告)日：2023-08-03

申请号：US18132321

申请日：2023-04-07

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Akhil Srinivasan ,  Peter Ajemba ,  Steven C. Jacks ,  Robert C. Mucic ,  Tyler R. Wong ,  Melissa Tsang ,  Chi-En Lin ,  Mohsen Askarinya ,  David Probst

IPC: A61M5/172 ,  A61B5/145 ,  A61M5/142 ,  A61B5/1495

CPC classification number: A61M5/1723 ,  A61B5/14532 ,  A61M5/14244 ,  A61B5/1495 ,  A61B5/4839

Abstract: Medical devices and related systems and methods are provided. A method of controlling medication delivery based on sensor input involves obtaining a measurement parameter representing an electrical response of a first instance of a sensing element to a physiological condition of a person. The measurement parameter is converted into a calibrated measurement parameter using calibration data specific to the first instance of the sensing element. The method further involves determining a measurement value using the calibrated measurement parameter as input to a performance model. The performance model is derived from historical calibrated measurement parameters and corresponding reference values. The historical calibrated measurement parameters are from other instances of the sensing element. A command is then determined based on the measurement value and sent to a medical device. The command causes the medical device to deliver a dose of medication influencing the physiological condition of the person.

公开(公告)号：US20230110585A1

公开(公告)日：2023-04-13

申请号：US18066212

申请日：2022-12-14

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Steven C. Jacks ,  Peter Ajemba ,  Akhil Srinivasan ,  Jacob E. Pananen ,  Sarkis Aroyan ,  Pablo Vazquez ,  Tri T. Dang ,  Ashley N. Sullivan ,  Raghavendhar Gautham

IPC: A61M5/172 ,  A61B5/145 ,  A61M5/142 ,  A61B5/1495

Abstract: Techniques disclosed herein relate to determining a calibrated measurement value indicative of a physiological condition of a patient using sensor calibration data and a performance model. In some embodiments, the techniques involve obtaining one or more electrical signals from a sensing element of a sensing arrangement, where the one or more electrical signals are influenced by a physiological condition in a body of a patient. The techniques also involve obtaining calibration data associated with the sensing element from a data storage element of the sensing arrangement, converting the one or more electrical signals into one or more calibrated measurement parameters using the calibration data, obtaining a performance model associated with the sensing element, obtaining personal data associated with the patient, and determining, using the performance model and based on the personal data and the one or more calibrated measurement parameters, a calibrated output value indicative of the physiological condition.

公开(公告)号：US20230060985A1

公开(公告)日：2023-03-02

申请号：US17972955

申请日：2022-10-25

Applicant: Medtronic MiniMed, Inc.

Inventor： Akhil Srinivasan ,  Barry P. Pham ,  Robert C. Mucic ,  Tyler R. Wong

IPC: A61B5/1486 ,  A61B5/145

Abstract: A single flex double-sided electrode useful in a continuous glucose monitoring sensor. In one example, a counter electrode is placed on the back-side of the flex and a work electrode is placed on the top-side of the sensor flex. The electrode is fabricated on physical vapor deposited metal deposited on a base substrate. Adhesion of the electrode to the base substrate is carefully controlled so that the electrode can be processed on the substrate and subsequently removed from the substrate after processing.

公开(公告)号：US20220054057A1

公开(公告)日：2022-02-24

申请号：US17466804

申请日：2021-09-03

Applicant: Medtronic MiniMed, Inc.

Inventor： Akhil Srinivasan ,  Melissa Tsang ,  Robert C. Mucic ,  Tyler R. Wong ,  Rui Kong ,  Barry P. Pham

IPC: A61B5/145 ,  A61B5/1486 ,  C12Q1/00 ,  B81B3/00 ,  G01N27/327

Abstract: The invention disclosed herein includes electrode compositions formed from processes that sputter metal in a manner that produces pillar architectures. Embodiments of the invention can be used in analyte sensors having such electrode architectures as well as methods for making and using these sensor electrodes. A number of working embodiments of the invention are shown to be useful in amperometric glucose sensors worn by diabetic individuals. However, the metal pillar structures have wide ranging applicability and should increase surface area and decrease charge density for catalyst layers or electrodes used with sensing, power generation, recording, and stimulation, in vitro and/or in the body, or outside the body.

公开(公告)号：US11134868B2

公开(公告)日：2021-10-05

申请号：US15922718

申请日：2018-03-15

Applicant: MEDTRONIC MINIMED, INC.

Inventor： Akhil Srinivasan ,  Melissa Tsang ,  Robert C. Mucic ,  Tyler R. Wong ,  Rui Kong ,  Barry P. Pham

IPC: A61B5/145 ,  A61B5/1486 ,  C12Q1/00 ,  B81B3/00 ,  G01N27/327 ,  C23C14/34

Abstract: The invention disclosed herein includes electrode compositions formed from processes that sputter metal in a manner that produces pillar architectures. Embodiments of the invention can be used in analyte sensors having such electrode architectures as well as methods for making and using these sensor electrodes. A number of working embodiments of the invention are shown to be useful in amperometric glucose sensors worn by diabetic individuals. However, the metal pillar structures have wide ranging applicability and should increase surface area and decrease charge density for catalyst layers or electrodes used with sensing, power generation, recording, and stimulation, in vitro and/or in the body, or outside the body.

公开(公告)号：US20210156815A1

公开(公告)日：2021-05-27

申请号：US16691403

申请日：2019-11-21

Applicant: Medtronic MiniMed, Inc.

Inventor： Robert Mucic ,  Zhenzhong Sun ,  Akhil Srinivasan

IPC: G01N27/327 ,  G01N27/31 ,  A61B5/145

Abstract: A glucose biosensor encasement includes a first membrane and a second membrane. The first membrane has a first interlocking segment. The second membrane has a second interlocking segment cooperating with the first interlocking segment of the first membrane to provide a cavity between the first membrane and the second membrane configured to receive a glucose sensor. At least one of the first membrane and the second membrane comprises a semi-permeable portion configured to regulate diffusion characteristics of glucose through the membrane to realize a sensitivity for a sensor in the cavity. A method is also provided.