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公开(公告)号:US20230123613A1
公开(公告)日:2023-04-20
申请号:US17501292
申请日:2021-10-14
Applicant: Medtronic MiniMed, Inc.
Inventor: Ashwin K. Rao , Quyen B. Ong , Michael E. Miller , Sarnath Chattaraj , Guangping Zhang , Poonam Gulati , Ariel Reider , Mohsen Askarinya , Michael N. Missaghi , Chi-En Lin , Xin Heng , Inthirai Somasuntharam , Melissa Tsang , Carlos E. Maldonado , Akhil Srinivasan
IPC: G01N27/327 , C12N9/04 , C12Q1/00 , G01N33/49
Abstract: The invention provides amperometric analyte sensor systems comprising one or more electrodes designed to monitor in vivo levels of 3-hydroxybutyrate (and optionally glucose as well) in order to facilitate the management of diabetic ketoacidosis. The invention further includes compositions, elements and methods useful with such amperometric analyte sensor systems.
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公开(公告)号:US12082924B2
公开(公告)日:2024-09-10
申请号:US16944450
申请日:2020-07-31
Applicant: Medtronic MiniMed, Inc.
Inventor: David Yueh-Hua Choy , Ellis Garai , Melissa Tsang , Anuj M. Patel
IPC: A61B5/145 , A61B5/00 , A61B5/1495
CPC classification number: A61B5/14532 , A61B5/1495 , A61B5/4839 , A61B2560/0214 , A61B2560/0223 , A61B2562/166 , A61B2562/227
Abstract: An analyte sensor apparatus including a sensing portion including one or more electrodes including a working electrode and one or more contacts for electrically connecting the sensor portion to control circuitry (e.g., a printed circuit board assembly, PCBA); and a circuit comprising the one or more contacts; wherein the circuit detects an electrical connection between the control circuitry without requiring exposure of the sensing portion to a fluid.
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公开(公告)号:US11654235B2
公开(公告)日:2023-05-23
申请号:US16569401
申请日:2019-09-12
Applicant: MEDTRONIC MINIMED, INC.
Inventor: Akhil Srinivasan , Peter Ajemba , Steven C. Jacks , Robert C. Mucic , Tyler R. Wong , Melissa Tsang , Chi-En Lin , Mohsen Askarinya , David Probst
CPC classification number: A61M5/1723 , A61B5/1495 , A61B5/14532 , A61M5/14244 , A61B5/145 , A61B5/4839 , A61B2560/0223 , A61B2560/0228 , A61B2560/0238 , A61M2005/14208 , G16H20/17
Abstract: Medical devices and related systems and methods are provided. A method of calibrating an instance of a sensing element involves obtaining fabrication process measurement data from a substrate having the instance of the sensing element fabricated thereon, obtaining a calibration model associated with the sensing element, determining calibration data associated with the instance of the sensing element for converting the electrical signals into a calibrated measurement parameter based on the fabrication process measurement data using the calibration model, and storing the calibration data in a data storage element associated with the instance of the sensing element.
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公开(公告)号:US20230053254A1
公开(公告)日:2023-02-16
申请号:US17401716
申请日:2021-08-13
Applicant: Medtronic MiniMed, Inc.
Inventor: Chi-En Lin , Akhil Srinivasan , David L. Probst , Melissa Tsang , Mohsen Askarinya , Riley Clayton Kimball , Robert McKinlay , Vu Nguyen , Wally Dong , Xin Heng , Brennan Toshner
IPC: A61B5/1468 , A61B5/145
Abstract: A method of testing one or more analyte sensors each comprising a first electrode; a second electrode; and a material layer disposed on or above the first electrode; the method including (a) applying a voltage potential to the first electrode with respect to the second electrode; (b) measuring a test signal comprising an output current from the first electrode that results from the application of the voltage potential; (c) using the test signal from (b) to observe an electrical characteristic of the analyte sensor; and (d) correlating the electrical characteristic a parameter associated with an electrochemical response of the analyte sensor to an analyte, wherein the testing is under dry conditions without exposure of the electrodes to a fluid containing the analyte or an in-vivo environment containing the analyte.
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公开(公告)号:US20240398290A1
公开(公告)日:2024-12-05
申请号:US18802086
申请日:2024-08-13
Applicant: Medtronic MiniMed, Inc.
Inventor: Soroush Hossein Yazdi , Melissa Tsang , Ellis Garai , Sadaf S. Seleh , Steven Lai , Luis A. Torres , Bradley Petkus , Xin Heng , Zhenzhong Sun , Akhil Srinivasan , Tyler R. Wong
IPC: A61B5/145 , A61B5/00 , A61B5/1486 , G16H20/10
Abstract: Methods, systems, and devices for continuous glucose monitoring. More particularly, the methods, systems, and devices describe a working electrode with a GOx sensor and a background electrode in which the background electrode has no GOx sensor. The system may then compare the first signal and the second signal to detect ingestion of a medication by the user. The system may generate a sensor glucose value based on the comparison.
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公开(公告)号:US20210077717A1
公开(公告)日:2021-03-18
申请号:US16569401
申请日:2019-09-12
Applicant: MEDTRONIC MINIMED, INC.
Inventor: Akhil Srinivasan , Peter Ajemba , Steven C. Jacks , Robert C. Mucic , Tyler R. Wong , Melissa Tsang , Chi-En Lin , Mohsen Askarinya , David Probst
IPC: A61M5/172 , A61B5/145 , A61M5/142 , A61B5/1495
Abstract: Medical devices and related systems and methods are provided. A method of calibrating an instance of a sensing element involves obtaining fabrication process measurement data from a substrate having the instance of the sensing element fabricated thereon, obtaining a calibration model associated with the sensing element, determining calibration data associated with the instance of the sensing element for converting the electrical signals into a calibrated measurement parameter based on the fabrication process measurement data using the calibration model, and storing the calibration data in a data storage element associated with the instance of the sensing element.
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公开(公告)号:US20200315504A1
公开(公告)日:2020-10-08
申请号:US16375752
申请日:2019-04-04
Applicant: MEDTRONIC MINIMED, INC.
Inventor: Chi-En Lin , David Probst , Mohsen Askarinya , Akhil Srinivasan , Melissa Tsang , Michael E. Miller , Parisa Kamgar
IPC: A61B5/145 , A61B5/1486 , C12Q1/54 , G01N27/327 , A61B5/00
Abstract: The invention includes method and materials designed to measure the material properties (e.g. thickness) of layers of material in a sensor using non-Faradaic EIS (Electrochemical Impedance Spectroscopy) methods. The methods are non-destructive, very sensitive and rapid. Typically in these methods, an AC voltage is applied to the desired material layer while the output current and therefore impedance is measured. This voltage can be applied in multiple frequencies in sweep mode in order to detect both the material and, for example, the thickness of the target material. In this way, EIS allows the characterization of properties of various layers of material disposed in devices such as electrochemical glucose sensors.
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公开(公告)号:US20230241315A1
公开(公告)日:2023-08-03
申请号:US18132321
申请日:2023-04-07
Applicant: MEDTRONIC MINIMED, INC.
Inventor: Akhil Srinivasan , Peter Ajemba , Steven C. Jacks , Robert C. Mucic , Tyler R. Wong , Melissa Tsang , Chi-En Lin , Mohsen Askarinya , David Probst
IPC: A61M5/172 , A61B5/145 , A61M5/142 , A61B5/1495
CPC classification number: A61M5/1723 , A61B5/14532 , A61M5/14244 , A61B5/1495 , A61B5/4839
Abstract: Medical devices and related systems and methods are provided. A method of controlling medication delivery based on sensor input involves obtaining a measurement parameter representing an electrical response of a first instance of a sensing element to a physiological condition of a person. The measurement parameter is converted into a calibrated measurement parameter using calibration data specific to the first instance of the sensing element. The method further involves determining a measurement value using the calibrated measurement parameter as input to a performance model. The performance model is derived from historical calibrated measurement parameters and corresponding reference values. The historical calibrated measurement parameters are from other instances of the sensing element. A command is then determined based on the measurement value and sent to a medical device. The command causes the medical device to deliver a dose of medication influencing the physiological condition of the person.
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公开(公告)号:US20220054057A1
公开(公告)日:2022-02-24
申请号:US17466804
申请日:2021-09-03
Applicant: Medtronic MiniMed, Inc.
Inventor: Akhil Srinivasan , Melissa Tsang , Robert C. Mucic , Tyler R. Wong , Rui Kong , Barry P. Pham
IPC: A61B5/145 , A61B5/1486 , C12Q1/00 , B81B3/00 , G01N27/327
Abstract: The invention disclosed herein includes electrode compositions formed from processes that sputter metal in a manner that produces pillar architectures. Embodiments of the invention can be used in analyte sensors having such electrode architectures as well as methods for making and using these sensor electrodes. A number of working embodiments of the invention are shown to be useful in amperometric glucose sensors worn by diabetic individuals. However, the metal pillar structures have wide ranging applicability and should increase surface area and decrease charge density for catalyst layers or electrodes used with sensing, power generation, recording, and stimulation, in vitro and/or in the body, or outside the body.
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公开(公告)号:US20220031205A1
公开(公告)日:2022-02-03
申请号:US16944450
申请日:2020-07-31
Applicant: Medtronic MiniMed, Inc.
Inventor: David Yueh-hua Choy , Ellis Garai , Melissa Tsang , Anuj M. Patel
IPC: A61B5/145 , A61B5/00 , A61B5/1495
Abstract: An analyte sensor apparatus including a sensing portion including one or more electrodes including a working electrode and one or more contacts for electrically connecting the sensor portion to control circuitry (e.g., a printed circuit board assembly, PCBA); and a circuit comprising the one or more contacts; wherein the circuit detects an electrical connection between the control circuitry without requiring exposure of the sensing portion to a fluid.
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