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73 条记录 (耗时 0.067 秒)

    CONTROLLED RELEASE FORMULATIONS USING INTELLIGENT POLYMERS
    33.
    发明申请
    CONTROLLED RELEASE FORMULATIONS USING INTELLIGENT POLYMERS 审中-公开
    使用智能聚合物控制释放配方

    公开(公告)号：US20080292700A1

    公开(公告)日：2008-11-27

    申请号：US12186853

    申请日：2008-08-06

    申请人： Tien NGHIEM ,  Graham Jackson

    发明人： Tien NGHIEM ,  Graham Jackson

    IPC分类号： A61K9/22 ,  A61P25/08 ,  A61P25/06 ,  A61P3/04 ,  A61P25/32 ,  A61P25/36 ,  A61P25/34 ,  A61P25/18

    CPC分类号： A61K31/35 ,  A61K9/2018 ,  A61K9/2054 ,  A61K9/2846

    摘要： A controlled release pharmaceutical composition comprises (a) topiramate or a pharmaceutically acceptable salt thereof, (b) a first intelligent polymer component; and (c) a second intelligent polymer component having opposite wettability characteristics to the first intelligent polymer component. The polymer components are effective for controlled release of the pharmaceutically active substance from the composition.

    摘要翻译： 控释药物组合物包含（a）托吡酯或其药学上可接受的盐，（b）第一智能聚合物组分; 和（c）具有与第一智能聚合物组分相反润湿特性的第二智能聚合物组分。 聚合物组分对于从组合物中控制释放药物活性物质是有效的。

    Fuel oil composition
    37.
    发明申请
    Fuel oil composition 有权
    燃油组成

    公开(公告)号：US20050000151A1

    公开(公告)日：2005-01-06

    申请号：US10856724

    申请日：2004-05-28

    申请人： Graham Jackson

    发明人： Graham Jackson

    IPC分类号： C10L1/192 ,  C08G8/00 ,  C08G61/02 ,  C10L1/02 ,  C10L1/14 ,  C10L1/16 ,  C10L1/18 ,  C10L1/198 ,  C10L1/22 ,  C10L10/14

    CPC分类号： C10L1/1981 ,  C08G61/02 ,  C10L1/143 ,  C10L1/1658 ,  C10L1/1973 ,  C10L1/1985 ,  C10L1/2222 ,  C10L1/224

    摘要： A fuel oil composition comprising a fuel oil and 0.1 to 10,000 ppm of a polymeric condensation product which is formed by the reaction of an aliphatic aldehyde or ketone, or a reactive equivalent, with either (i) a straight or branched chain C1-C7 alkyl ester of p-hydroxybenzoic acid, or with (ii) a branched chain C8-C16 alkyl ester of p-hydroxybenzoic acid, or with (iii) a mixture of long chain C8-C18 alkyl esters of p-hydroxybenzoic acid, at least one of said alkyls being branched. The polymeric condensation product improves the cold flow characteristics of the fuel oil.

    摘要翻译： 一种燃料油组合物，其包含燃料油和0.1至10,000ppm的聚合缩合产物，其通过脂族醛或酮或反应性当量与（i）直链或支链C 1 -C 7烷基 对 - 羟基苯甲酸的酯或与（ii）对羟基苯甲酸的支链C 8 -C 16烷基酯或（iii）对羟基苯甲酸的长链C8-C18烷基酯的混合物，至少一种 的所述烷基是支链的。 聚合物缩合产物改善燃料油的冷流特性。

    Process for the chlorination of sugars
    40.
    发明授权
    Process for the chlorination of sugars 失效
    糖的氯化处理

    公开(公告)号：US4977254A

    公开(公告)日：1990-12-11

    申请号：US388657

    申请日：1989-08-02

    申请人： Nigel J. Homer ,  Graham Jackson ,  George H. Sankey ,  Philip J. Simpson

    发明人： Nigel J. Homer ,  Graham Jackson ,  George H. Sankey ,  Philip J. Simpson

    IPC分类号： C07B61/00 ,  C07H5/02 ,  C07H11/00 ,  C07H13/04

    CPC分类号： C07H5/02 ,  C07H11/00 ,  C07H13/04

    摘要： Sugars and partly protected sugar derivatives are chlorinated by reaction of unprotected hydroxyl groups with thionyl chloride to form a persulphite followed by decomposition of the sulphite groups to form chlorosulphites, displacement of the chlorosulphite groups and insertion of chlorine atoms at one or more positions, characterised in that formation and displacement of the chlorosulphite groups and insertion of chlorine atoms is effected by reaction with thionyl chloride in an inert solvent in the presence of a quaternary salt of the general formula:N.sup.+ R.sup.1 R.sup.2 R.sup.3 R.sup.4 Cl.sup.- (I)wherein R.sup.1, R.sup.2 and R.sup.3, which may be the same or different, each represent a lower alkyl group, and R.sup.4 represents a hydrocarbon group with at least seven carbon atoms; and, when the sugar or partly protected sugar derivative has more than three unprotected hydroxyl groups, the process comprises the following stages:(a) reaction of the sugar or partly protected sugar derivative with thionyl chloride in the presence of pyridine to form a persulphite;(b) isolation of the polysulphite to remove free pyridine; and(c) reaction of the isolated polysulphite with thionyl chloride in an inert solvent or suspension medium in the presence of a quaternary salt of the general formula (I).