专利检索 ap:("Niels Kristian Klausen" OR "Soren Bjorn" OR "Carsten Behrens" OR "Patrick William Garibay") AND inv:"Carsten Behrens" 第 4 页

31.

发明申请
GROWTH HORMONE CONJUGATES 审中-公开
标题翻译：生长激素

公开(公告)号：US20130143815A1

公开(公告)日：2013-06-06

申请号：US13809681

申请日：2011-07-15

申请人： Henrik Sune Andersen , Kjeld Madsen , Helle Demuth , Christine Bruun Schioedt , Leif Noerskov-Lauritsen , Peter Thygesen , Carsten Behrens , Mette Guldbrandt

发明人： Henrik Sune Andersen , Kjeld Madsen , Helle Demuth , Christine Bruun Schioedt , Leif Noerskov-Lauritsen , Peter Thygesen , Carsten Behrens , Mette Guldbrandt

IPC分类号： C07K14/61

CPC分类号： C07K14/61 , A61K47/554

摘要： The present invention relates to growth hormone conjugates comprising a bile acid residue, said conjugation may occur through wt or mutant amino acid residues. The growth hormone polypeptide may be wt human growth hormone or a growth hormone variant.

摘要翻译： 本发明涉及包含胆汁酸残基的生长激素缀合物，所述缀合可以通过wt或突变体氨基酸残基进行。生长激素多肽可以是人生长激素或生长激素变体。

32.

发明申请
Glucagon Antagonists/Inverse Agonists 审中-公开
标题翻译：胰高血糖素拮抗剂/反激动剂

公开(公告)号：US20090143592A1

公开(公告)日：2009-06-04

申请号：US11949075

申请日：2007-12-03

申请人： Jesper Lau , Peter Madsen , Christian Sams , Carsten Behrens , Josef Vagner , Inge Thoger Christensen , Behrend Frederik Lundt , Ulla Grove Sidelmann , Henning Thogersen , Anthony L. Ling , Michael Bruno Plewe , Larry Kenneth Truesdale , Anker Steen Jogensen , Janos Tibor Kodra , Shenghua Shi

发明人： Jesper Lau , Peter Madsen , Christian Sams , Carsten Behrens , Josef Vagner , Inge Thoger Christensen , Behrend Frederik Lundt , Ulla Grove Sidelmann , Henning Thogersen , Anthony L. Ling , Michael Bruno Plewe , Larry Kenneth Truesdale , Anker Steen Jogensen , Janos Tibor Kodra , Shenghua Shi

IPC分类号： C07D211/88 , C07D257/06 , C07D333/24 , C07C57/62

CPC分类号： C07D209/48 , C07B2200/07 , C07C237/36 , C07C237/42 , C07C243/38 , C07C271/56 , C07C271/58 , C07C275/24 , C07C275/26 , C07C275/28 , C07C275/30 , C07C275/34 , C07C275/36 , C07C275/38 , C07C275/42 , C07C275/60 , C07C275/62 , C07C311/47 , C07C317/22 , C07C317/32 , C07C317/42 , C07C323/21 , C07C323/44 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2602/08 , C07C2602/10 , C07C2602/42 , C07C2603/18 , C07C2603/68 , C07C2603/94 , C07D209/08 , C07D211/58 , C07D213/75 , C07D215/38 , C07D231/40 , C07D235/30 , C07D257/06 , C07D277/72 , C07D295/13 , C07D295/135 , C07D307/68 , C07D317/66 , C07D319/18 , C07D319/20 , C07D333/20 , C07D333/38 , C07D333/60 , C07D333/68 , C07D333/70 , C07D409/12 , C07D417/12 , C07D487/04

摘要： A novel class of compounds, which act to antagonize the action of the glucagon hormone on the glucagon receptor. Owing to their antagonizing effect of the glucagon receptor the compounds may be suitable for the treatment and/or prevention of any glucagon-mediated conditions and diseases such as hyperglycemia, Type 1 diabetes, Type 2 diabetes and obesity.

摘要翻译： 一类新颖的化合物，其作用是拮抗胰高血糖素激素对胰高血糖素受体的作用。由于它们对胰高血糖素受体的拮抗作用，所述化合物可适用于治疗和/或预防任何胰高血糖素介导的病症和疾病如高血糖症，1型糖尿病，2型糖尿病和肥胖症。

33.

发明授权
Non-peptide GLP-1 agonists 失效
标题翻译：非肽GLP-1激动剂

公开(公告)号：US06927214B1

公开(公告)日：2005-08-09

申请号：US09483504

申请日：2000-01-14

申请人： Min Teng , Larry Kenneth Truesdale , Dilip Bhumralkar , Dan Kiel , Michael D. Johnson , Christine Thomas , Anker Steen Jorgensen , Peter Madsen , Preben Houlberg Olesen , Liselotte Bjerre Knudsen , Ingrid Vivika Petterson , Johannes Cornelis de Jong , Carsten Behrens , Janos Tibor Kodra , Jesper Lau

发明人： Min Teng , Larry Kenneth Truesdale , Dilip Bhumralkar , Dan Kiel , Michael D. Johnson , Christine Thomas , Anker Steen Jorgensen , Peter Madsen , Preben Houlberg Olesen , Liselotte Bjerre Knudsen , Ingrid Vivika Petterson , Johannes Cornelis de Jong , Carsten Behrens , Janos Tibor Kodra , Jesper Lau

IPC分类号： C07D215/20 , C07D215/36 , C07D241/44 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/04 , C07D405/12 , C07D417/12 , C07D491/10 , C07D495/04 , A61K31/33 , A61K31/495 , C07D239/00 , C07D241/36

CPC分类号： C07D491/10 , C07D215/20 , C07D215/36 , C07D241/44 , C07D401/12 , C07D403/04 , C07D403/12 , C07D405/04 , C07D405/12 , C07D417/12 , C07D495/04

摘要： Novel non-peptide GLP-1 agonists, pharmaceutical compositions comprising them, use of the non-peptide GLP-1 agonists for the preparation of pharmaceutical compositions and methods for the treatment and/or prevention of disorders and diseases wherein an activation of the human GLP-1 receptor is beneficial, especially metabolic disorders such as IGT, Type 1 diabetes, Type 2 diabetes and obesity.

摘要翻译： 新型非肽GLP-1激动剂，包含它们的药物组合物，使用非肽GLP-1激动剂来制备用于治疗和/或预防疾病和疾病的药物组合物和方法，其中人GLP -1受体是有益的，特别是代谢疾病如IGT，1型糖尿病，2型糖尿病和肥胖。

34.

发明授权
Glucagon antagonists/inverse agonists 失效
标题翻译：胰高血糖素拮抗剂/反向激动剂

公开(公告)号：US06881746B2

公开(公告)日：2005-04-19

申请号：US10448529

申请日：2003-05-30

申请人： Jesper Lau , Inge Thoger Christensen , Peter Madsen , Paw Bloch , Carsten Behrens , Janos Tibor Kodra , Poul Enrico Nielsen

发明人： Jesper Lau , Inge Thoger Christensen , Peter Madsen , Paw Bloch , Carsten Behrens , Janos Tibor Kodra , Poul Enrico Nielsen

IPC分类号： A61K31/195 , A61K31/198 , A61K31/41 , A61K31/4439 , A61K45/06 , A61K31/425 , A61P3/00 , C07D277/04

CPC分类号： A61K45/06 , A61K31/195 , A61K31/198 , A61K31/41 , A61K31/4439 , A61K2300/00

摘要： Novel compounds that act to antagonize the action of the glucagon peptide hormone on the glucagon receptor. More particularly, it relates to glucagon antagonists or inverse agonists.

摘要翻译： 用于拮抗胰高血糖素肽激素对胰高血糖素受体的作用的新型化合物。更具体地，涉及胰高血糖素拮抗剂或反向激动剂。