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    Methods for asymmetrical irradiation of a body cavity
    31.
    发明申请
    Methods for asymmetrical irradiation of a body cavity 有权
    体腔不对称照射方法

    公开(公告)号：US20080281142A1

    公开(公告)日：2008-11-13

    申请号：US12151153

    申请日：2008-05-02

    申请人： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

    发明人： Paul Lubock ,  Michael L. Jones ,  Frank R. Louw

    IPC分类号： A61N5/00

    CPC分类号： A61N5/1014 ,  A61N5/1002 ,  A61N5/1015 ,  A61N2005/1003 ,  A61N2005/1004 ,  A61N2005/1005 ,  A61N2005/1018 ,  A61N2005/1024

    摘要： The disclosure describes devices and methods for asymmetrical irradiation at a body cavity or site, such as after removal of tissue, e.g. biopsy or cancer. One device includes a lumen which is off-set or off-settable from a longitudinal axis to increase the intensity of radiation received from a radiation source by a first tissue portion surrounding the body cavity and to reduce or minimize radiation received by a second tissue portion (e.g. healthy tissue) surrounding the body cavity.

    摘要翻译： 本公开描述了用于在体腔或部位不对称照射的装置和方法，例如在去除组织之后，例如， 活检或癌症。 一个装置包括从纵向轴线偏移或不可固定的内腔，以增加围绕体腔的第一组织部分从辐射源接收的辐射的强度，并且减少或最小化由第二组织部分接收的辐射 （例如健康组织）。

    Methods for tissue irradiation with shielding
    32.
    发明申请
    Methods for tissue irradiation with shielding 失效
    屏蔽组织照射方法

    公开(公告)号：US20070191667A1

    公开(公告)日：2007-08-16

    申请号：US11593678

    申请日：2006-11-06

    申请人： Paul Lubock ,  Michael L. Jones

    发明人： Paul Lubock ,  Michael L. Jones

    IPC分类号： A61N5/00

    CPC分类号： A61N5/1015 ,  A61B2017/3419 ,  A61N2005/1005

    摘要： Devices and methods are disclosed for treatment to tissue surrounding a body cavity or other intracorporeal site, such as after removal of tissue, e.g. cancer. Such a device includes a treatment location on a distal portion of the device with one or more radiation shielding components that partially encircle a radiation source at the treatment location to control emitted radiation from the radiation source. The device minimizes radiation damage to healthy tissue surrounding the body cavity or other site while irradiating tissue not shielded by the radiation shielding components. A device embodying features of the invention can include a sealing member at a location on a shaft of the device proximal to a treatment location to seal the passageway leading to the body cavity.

    摘要翻译： 公开了用于治疗围绕体腔或其他体内部位的组织的装置和方法，例如在去除组织后，例如， 癌症。 这种装置包括在装置的远端部分上的处理位置，其中一个或多个辐射屏蔽部件在处理位置部分地环绕辐射源以控制来自辐射源的辐射。 该装置最小化对体腔或其他部位周围的健康组织的辐射损伤，同时辐射未被辐射屏蔽部件屏蔽的组织。 体现本发明特征的装置可包括密封构件，该密封构件位于靠近处理位置的装置的轴上的位置处，以密封通向体腔的通道。

    Breast biopsy system and methods
    34.
    发明授权
    Breast biopsy system and methods 有权
    乳腺活检系统及方法

    公开(公告)号：US06699206B2

    公开(公告)日：2004-03-02

    申请号：US09976916

    申请日：2001-10-11

    申请人： Fred H. Burbank ,  Michael L. Jones ,  Paul Lubock

    发明人： Fred H. Burbank ,  Michael L. Jones ,  Paul Lubock

    IPC分类号： A61B1000

    CPC分类号： A61B10/0266 ,  A61B10/02 ,  A61B17/00491 ,  A61B17/32056 ,  A61B17/320725 ,  A61B17/3417 ,  A61B18/14 ,  A61B18/1487 ,  A61B18/1492 ,  A61B90/17 ,  A61B90/37 ,  A61B2017/3488 ,  A61B2018/00208 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/00333 ,  A61B2018/00898 ,  A61B2018/0091 ,  A61B2018/00916 ,  A61B2018/1253 ,  A61B2018/126 ,  A61B2018/1407 ,  A61B2018/1475 ,  A61B2018/162 ,  A61B2090/3908

    摘要： An apparatus and method are provided for precisely isolating a target lesion in a patient's body tissue, resulting in a high likelihood of“clean” margins about the lesion when it is removed for diagnosis and/or therapy. This approach advantageously will often result in the ability to both diagnose and treat a malignant lesion with only a single percutaneous procedure, with no follow-up percutaneous or surgical procedure required, while minimizing the risk of migration of possibly cancerous cells from the lesion to surrounding tissue or the bloodstream. In particular, the apparatus comprises a biopsy instrument having a distal end adapted for entry into the patient's body, a longitudinal shaft, and a cutting element disposed along the shaft. The cutting element is actuatable between a radially retracted position and a radially extended position. Advantageously, the instrument is rotatable about its axis in the radially extended position to isolate a desired tissue specimen from surrounding tissue by defining a peripheral margin about the tissue specimen. Once the tissue specimen is isolated, it may be segmented by further manipulation of the cutting element, after which the tissue segments are preferably individually removed from the patient's body through a cannula or the like. Alternatively, the specimen may be encapsulated and removed as an intact piece.

    摘要翻译： 提供了一种用于精确地分离患者体内组织中的靶病变的装置和方法，导致当其被去除用于诊断和/或治疗时，对病变的“清洁”边缘的高可能性。 这种方法有利地经常导致仅使用单一经皮手术来诊断和治疗恶性病变的能力，而不需要随访的经皮或外科手术，同时最小化可能的癌细胞从病变迁移到周围的风险 组织或血液。 特别地，该装置包括具有适于进入患者身体的远端的活检器械，纵向轴和沿轴设置的切割元件。 切割元件可在径向缩回位置和径向延伸位置之间致动。 有利地，仪器可以在其径向延伸位置中绕其轴线旋转，以通过围绕组织样本限定周边边缘来将期望的组织样本与周围组织隔离。 一旦组织样本被分离，则可以通过进一步操纵切割元件来分割组织样本，之后组织片段优选通过套管等从患者身体单独地移除。 或者，样品可以作为完整的片段被包封和去除。

    Marker delivery device with releasable plug
    37.
    发明授权
    Marker delivery device with releasable plug 有权
    带可释放插头的标记输送装置

    公开(公告)号：US08361082B2

    公开(公告)日：2013-01-29

    申请号：US13037971

    申请日：2011-03-01

    申请人： Michael L. Jones ,  Paul Lubock ,  John Merritt

    发明人： Michael L. Jones ,  Paul Lubock ,  John Merritt

    IPC分类号： A61B17/00

    CPC分类号： A61B5/064 ,  A61B5/055 ,  A61B5/062 ,  A61B6/12 ,  A61B8/0833 ,  A61B10/02 ,  A61B17/0057 ,  A61B90/39 ,  A61B2017/00637 ,  A61B2017/00898 ,  A61B2090/3908 ,  A61B2090/3925 ,  A61B2090/3954 ,  A61B2090/3966 ,  A61B2090/3987 ,  A61K49/12 ,  A61K49/18 ,  A61K2123/00 ,  A61M5/007 ,  A61M37/0069

    摘要： A marker delivery device includes an elongated delivery cannula which has a distal end section, an inner lumen and a discharge opening in the distal end section in communication with the inner lumen. At least one elongated fibrous marker body is slidably disposed within the inner lumen of the elongated delivery cannula. The at least one elongated fibrous marker body includes a plurality of bioabsorbable polymeric strands. The strands are compressed to a compressed configuration and bound together in the compressed configuration with a polymer binding agent prior to insertion into the elongated delivery cannula. A releasable plug is disposed within a distal portion of the inner lumen and distal to the at least one elongated fibrous marker body so as to at least partially occlude the discharge opening in the distal end section.

    摘要翻译： 标记输送装置包括细长的输送套管，其具有与内腔连通的远端部分中的远端部分，内腔和排出口。 至少一个细长的纤维标记物体可滑动地设置在细长的输送套管的内腔内。 所述至少一个细长的纤维标记物主体包括多个生物可吸收的聚合物链。 股线被压缩成压缩构型并且在插入细长的输送套管之前用压缩构型与聚合物粘合剂结合在一起。 可释放插塞设置在内腔的远侧部分内并且远离至少一个细长纤维标记体，以至少部分地封闭远端部分中的排出口。