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公开(公告)号:US20050238586A1
公开(公告)日:2005-10-27
申请号:US11159209
申请日:2005-06-23
申请人: Andrew Sutton , Richard Johnson
发明人: Andrew Sutton , Richard Johnson
CPC分类号: A61K9/5052 , A61K9/1658 , A61K9/5031 , A61K47/42 , A61K49/22 , A61K49/223
摘要: Microspheres are prepared by a process comprising (i) spray-drying a solution or dispersion of a wall-forming material in order to obtain intermediate microspheres and (ii) reducing the water-solubility of at least the outside of the intermediate microspheres. Suitable wall-forming materials include proteins such as albumin and gelatin. The microspheres have walls of 40-500 nm thick and are useful in ultrasonic imaging. The control of size, size distribution and degree of insolubilisation and cross-linking of the wall-forming material allows novel microsphere preparations to be produced. In particular, the microspheres may be 15-20 μm, targeted to selected areas of the body or of prolonged life in the circulation.
摘要翻译: 微球通过包括(i)喷雾干燥成壁材料的溶液或分散体以获得中间体微球体的方法制备,和(ii)降低至少中间微球体外部的水溶性。 合适的成壁材料包括蛋白质如白蛋白和明胶。 微球具有40-500nm厚的壁,并且可用于超声成像。 壁形成材料的尺寸,尺寸分布和不溶解和交联程度的控制允许制备新的微球制剂。 特别地,微球可以是15-20毫米,靶向身体的选定区域或在循环中延长使用寿命。
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公开(公告)号:US20050139282A1
公开(公告)日:2005-06-30
申请号:US10937454
申请日:2004-09-09
申请人: Richard Johnson , Christophe Loret
发明人: Richard Johnson , Christophe Loret
CPC分类号: H01Q17/00
摘要: A microwave-absorbing material which can be dispensed from standard form-in-place dispensing equipment combines a liquid resin system with a magnetic or lossy dielectric filler. In a preferred embodiment, the liquid resin system is a silicone resin system and the magnetic filler is iron carbonyl powder. The microwave-absorbing material is dispensed into a housing for electronic equipment. It may be dispensed into a cavity in the housing where it self-levels and cures. Alternatively, it may be dispensed onto a surface in the housing where, because of its thixotropic properties, it holds its shape and forms a pad of cured microwave-absorbing material thereon.
摘要翻译: 可以从标准现场分配设备中分配的微波吸收材料将液体树脂系统与磁性或有损耗的介电填料相结合。 在优选的实施方案中,液体树脂体系是有机硅树脂体系,磁性填料是羰基铁粉。 将微波吸收材料分配到用于电子设备的外壳中。 它可以被分配到壳体中的空腔中,其中它自我水平和固化。 或者,其可以分配到壳体中的表面上,其中由于其触变特性,其保持其形状并在其上形成固化的微波吸收材料垫。
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公开(公告)号:US20050116090A1
公开(公告)日:2005-06-02
申请号:US10765571
申请日:2004-01-27
申请人: Thomas Welty , Randy Berg , Thomas Fredrickson , Richard Johnson
发明人: Thomas Welty , Randy Berg , Thomas Fredrickson , Richard Johnson
摘要: A non-lethal nose cone adapted for the delivery of non-lethal munitions with a projectile weapon. The non-lethal nose cone is manufactured of materials, such as polymers and ceramics, selected for traits including high strength and uniformity when exposed to typical projectile firing conditions as well as an ability to avoid becoming lethal shrapnel upon detonation of an internal charge for disbursing the non-lethal submunitions through pre-scored grooves on the nose cone. Generally, the non-lethal nose cone is intended for use with a projectile having an integral kinetic energy reduction system that may serve the dual role of assisting with submunition ejection through the pre-scored grooves as well as reducing the fall rate of the projectile to non-lethal velocities. Generally, the non-lethal nose cone is adapted for use with standoff delivery systems such as mortar rounds, air delivery systems and artillery.
摘要翻译: 一种非致命的鼻锥适用于用射弹武器运送非致命弹药。 非致死性鼻锥由诸如聚合物和陶瓷的材料制成,其被选择用于当暴露于典型的射弹烧制条件时具有高强度和均匀性的性状,以及在引爆内部充电以避免成为致命的弹片时的能力 非致命子弹通过鼻锥上的预刻槽。 通常,非致命的鼻锥体旨在与具有整体动能减少系统的射弹一起使用,该系统可以通过预刻槽帮助辅助弹药的双重作用,并且将射弹的降落率降低到 非致命的速度。 通常,非致命的鼻锥适用于支架输送系统,例如迫击炮弹,空气输送系统和火炮。
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公开(公告)号:US20050090447A1
公开(公告)日:2005-04-28
申请号:US10938088
申请日:2004-09-10
申请人: Richard Johnson , Shelley Maves
发明人: Richard Johnson , Shelley Maves
IPC分类号: A61K38/08 , A61K47/48 , A61L15/32 , A61L26/00 , A61L29/00 , A61P37/04 , C07K14/47 , C07K7/06
CPC分类号: A61L26/0047 , A61K38/08 , A61K47/64 , A61L15/32 , C07K14/472
摘要: The present invention relates to compositions, including pharmaceutical compositions that promote complement activation, and contain a polypeptide X1-C-X2-X3-X4-X5-X6-X7-X8-C-X9 as described. The invention further relates to a method of promoting complement activation in a patient by administering a pharmaceutical composition as described herein. Further provided are a wound dressing and an anti-tumor cell antigen antibody formulation containing pharmaceutical compositions of the present invention.
摘要翻译: 本发明涉及组合物,包括促进补体活化的药物组合物,并且含有多肽X 1 -CX 2 -X 3 -X 4→5→5→6→-X 7→-X 8 -CX 如上所述。 本发明还涉及通过施用本文所述的药物组合物促进患者补体活化的方法。 还提供了包含本发明的药物组合物的伤口敷料和抗肿瘤细胞抗原抗体制剂。
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公开(公告)号:US06748589B1
公开(公告)日:2004-06-08
申请号:US09421484
申请日:1999-10-20
申请人: Richard Johnson , Guillermo Rozas
发明人: Richard Johnson , Guillermo Rozas
IPC分类号: G06F945
CPC分类号: G06F9/30065 , G06F8/4441
摘要: A method for increasing the speed of execution by a processor including the steps of selecting a sequence of instructions to optimize, optimizing the sequence of instructions, creating a duplicate of instructions from the sequence of instructions which has been selected to optimize, executing the optimized sequence of instructions, and responding to an error during the execution of the optimized sequence of instructions by rolling back to the duplicate of instructions from the sequence of instructions.
摘要翻译: 一种用于增加处理器执行速度的方法,包括以下步骤:选择指令序列以优化指令序列,优化指令序列,从已被选择优化的指令序列中创建指令副本,执行优化序列 的指令,并且通过从指令序列回滚到指令的副本,在执行优化的指令序列期间响应错误。
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公开(公告)号:US06292832B1
公开(公告)日:2001-09-18
申请号:US09175673
申请日:1998-10-20
申请人: Dhaval N. Shah , Richard Johnson
发明人: Dhaval N. Shah , Richard Johnson
IPC分类号: G06F1314
CPC分类号: H04L29/06 , H04L29/12066 , H04L41/50 , H04L41/5022 , H04L61/1511 , H04L67/1002 , H04L67/1008 , H04L67/101 , H04L67/1012 , H04L67/1017 , H04L67/1019 , H04L67/1038
摘要: The present invention relates to a system and method for selecting a service in a network, such as the Internet. According to an embodiment of the present invention, a user, such as a network administrator, may configure the system and method of the present invention to determine a “best” service based on a user configured metric. Examples of user configured metrics include director response protocol (DRP) external metrics, DRP internal metrics, DRP server metrics, DRP multi-exit discriminator (MED), and DRP round trip time (RTT). Metric information is herein meant to include any criteria used to select a “best” service. Examples of metric information include portion, random, and administrative costs, as well as DRP external metrics, DRP internal metrics, DRP server, DRP MED, and DRP RTT. The service associated with the best metric information is then selected as a resolution for the requested host name.
摘要翻译: 本发明涉及一种在诸如因特网的网络中选择服务的系统和方法。 根据本发明的实施例,诸如网络管理员的用户可以配置本发明的系统和方法,以基于用户配置的度量来确定“最佳”服务。 用户配置的度量的示例包括指导者响应协议(DRP)外部度量,DRP内部度量,DRP服务器度量,DRP多出口标识符(MED)和DRP往返时间(RTT)。 度量信息在这里意在包括用于选择“最佳”服务的任何标准。 度量信息的示例包括部分,随机和管理成本,以及DRP外部度量,DRP内部度量,DRP服务器,DRP MED和DRP RTT。 然后选择与最佳度量信息相关联的服务作为所请求的主机名的分辨率。
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公开(公告)号:US20190185875A1
公开(公告)日:2019-06-20
申请号:US16292489
申请日:2019-03-05
申请人: Jason Bull , David Butruille , Sam Eathington , Marlin Edwards , Anju Gupta , Richard Johnson , Wayne Kennard , Jennifer Rinehart , Kunsheng Wu
发明人: Jason Bull , David Butruille , Sam Eathington , Marlin Edwards , Anju Gupta , Richard Johnson , Wayne Kennard , Jennifer Rinehart , Kunsheng Wu
CPC分类号: C12N15/8275 , A01H1/02 , A01H1/04 , A01H5/10 , A01N57/20 , C12N15/821 , C12N15/8286 , Y02A40/162 , A01N2300/00
摘要: The present invention provides breeding methods and compositions to enhance the germplasm of a plant. The methods describe the identification and accumulation of transgenes and favorable haplotype genomic regions in the germplasm of a breeding population of crop plants.
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公开(公告)号:US20170080367A1
公开(公告)日:2017-03-23
申请号:US15370861
申请日:2016-12-06
申请人: Richard Johnson , Benjamin Harrison
发明人: Richard Johnson , Benjamin Harrison
CPC分类号: B01D29/41 , B01D29/111 , B01D29/395 , B01D35/30 , B01D36/001 , B01D39/14 , B01D2201/24 , B01D2201/302 , B01D2201/307
摘要: A filter assembly is provided. The filter assembly includes a filter cartridge with a containment bag including a vent port and a support housing, including a split lid.
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公开(公告)号:US08650555B1
公开(公告)日:2014-02-11
申请号:US12037853
申请日:2008-02-26
申请人: Richard Johnson , Guillermo Rozas
发明人: Richard Johnson , Guillermo Rozas
IPC分类号: G06F9/45
CPC分类号: G06F9/30065 , G06F8/4441
摘要: A method of code execution by a processor including duplicating a first set of instructions to generate a second set of instructions, modifying the second set of instructions, executing the modified set of instructions, and upon exiting the modified set of instructions, loading an updated state of the processor.
摘要翻译: 一种由处理器执行代码的方法,包括复制第一组指令以产生第二组指令,修改第二组指令,执行修改的指令集,以及在退出修改的指令集之后,加载更新的状态 的处理器。
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公开(公告)号:US08602777B2
公开(公告)日:2013-12-10
申请号:US13471099
申请日:2012-05-14
申请人: Bryce A. Way , Christopher U. Phan , Dana Leigh Gelman Keiles , Richard Johnson , Phillip Abatelli
发明人: Bryce A. Way , Christopher U. Phan , Dana Leigh Gelman Keiles , Richard Johnson , Phillip Abatelli
IPC分类号: A61C3/00
CPC分类号: A61C8/0096 , A61B17/1604 , A61B17/1673 , A61B2017/00128 , A61B2017/0046 , A61B2017/1648 , A61B2017/561 , A61B2090/062 , A61B2090/065 , A61C1/082 , A61C1/084 , A61C3/02 , A61C7/02 , A61C7/12 , A61C8/0089 , A61C19/04
摘要: A device for increasing movement of a tooth in a jaw includes a handle, an elongate member extending from the handle, a screw tip at a distal end of the elongate member, and a sleeve. The screw tip is configured to drill into cortical bone of the jaw to increase movement of the tooth. The sleeve is configured to move along the elongate member to vary the length of exposed screw tip.
摘要翻译: 用于增加颚中齿的运动的装置包括手柄,从手柄延伸的细长构件,在细长构件的远端处的螺钉尖端和套筒。 螺钉尖端构造成钻入颌骨的皮质骨以增加牙齿的运动。 套筒构造成沿着细长构件移动以改变暴露的螺钉尖端的长度。
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