摘要:
Antibody/signal-generating moiety conjugates are disclosed that include an antibody covalently linked to a signal-generating moiety through a heterobifunctional polyalkyleneglycol linker. The disclosed conjugates show exceptional signal-generation in immunohistochemical and in situ hybridization assays on tissue sections and cytology samples. In one embodiment, enzyme-metallographic detection of nucleic acid sequences with hapten-labeled probes can be accomplished using the disclosed conjugates as a primary antibody without amplification.
摘要:
Apparatuses and methods for performing minimally invasive medical procedures are disclosed herein. In one example, an apparatus includes an elongate body that has a deformable distal portion and defines a lumen, the lumen extends through the deformable distal portion. The deformable distal portion has a cutting portion and defines an opening. The elongate body has a first configuration in which the opening is a first size and a second configuration in which the opening is a second size smaller than the first size of the opening. The elongate body in the first configuration is configured to be percutaneously inserted at least partially into a tissue such that at least a portion of the tissue is disposed within the lumen. The elongate body is configured to move to the second configuration when the elongate body reaches a threshold temperature while inserted in the tissue.
摘要:
An integrated circuit (IC) for convergent rounding including: an adder circuit configured to produce a summation; a comparison circuit configured to bitwise compare the summation with an input pattern, bitwise mask the comparison using a mask, and combine the masked comparison to produce a comparison bit; and rounding circuitry for rounding the summation based at least in part on the comparison bit.
摘要:
It is sometimes desirable to protect a design used in a PLD from being copied. If the design is stored in a different device from the PLD and read into the PLD through a bitstream, an unencrypted bitstream could be observed and copied as it is being loaded. According to the invention, a bitstream for configuring a PLD with an encrypted design includes unencrypted words for controlling loading of the configuration bitstream and encrypted words that actually specify the design.
摘要:
A digital signal processing block having: 1) a first digital signal processing element including: a first multiplexer of a first plurality of multiplexers, the first multiplexer selecting between a first data input and a first zero constant input; and a first arithmetic unit coupled to the first plurality of multiplexers, the first arithmetic logic unit configured for addition; and 2) a second digital signal processing element including: a second multiplexer of a second plurality of multiplexers, the second multiplexer selecting between a second data input and a second zero constant input; and a second arithmetic unit coupled to the second plurality of multiplexers and to a third multiplexer of the first plurality of multiplexers, the second arithmetic unit configured for addition.
摘要:
A clock signal is monitored to detect a transition from a first logic state to a second logic state. Once this transition is detected, subsequent transitions of the clock signal are ignored for a predetermined time period during which signal interference is most significant. After lapse of the predetermined time period, the clock signal is again monitored to detect subsequent state transitions. In some embodiments, the clock signal is delayed using a delay circuit to produce a delayed clock signal which is used to force the clock signal to the second logic state for a predetermined time period. In one embodiment, the predetermined time period is user-selectable via one or more selectable taps on the delay circuit.
摘要:
A programmable logic device (PLD) comprises at least one configurable element, and a plurality of programmable logic elements for configuring the configurable element(s). Alternatively, a PLD comprises an interconnect structure and a plurality of programmable logic elements for configuring the interconnect structure. In either embodiment, at least one of the programmable logic elements includes N memory cells. A predetermined one of the N memory cells forms part of a memory slice, wherein at least a portion of each slice of the programmable logic device is allocated to either configuration data or user data memory. Typically, one memory slice provides one configuration of the programmable logic device. In accordance with one embodiment, a memory access port is coupled between at least one of the N memory cells and either one configurable element or the interconnect, thereby facilitating loading of new configuration data into other memory slices during the one configuration. The new configuration data may include off-chip or on-chip data. The present invention typically allocates at least one slice to user data memory and includes means for disabling access to at least one of the N memory cells.
摘要:
A low voltage interface circuit with a high voltage tolerance enables devices with different power supply levels to be efficiently coupled together without significant leakage current or damage to the circuits. One embodiment of the present invention comprises a tri-state control circuit, a data path, a reference voltage circuit, and an isolation circuit. The interface circuit provides a high impedance receive mode. In this mode, when a voltage is applied to the I/O pin of the interface circuit which is sufficiently greater than the interface circuit power supply voltage, the isolation circuit isolates the power supply from the I/O pin. The interface circuit also protects all of the transistors from gate to bulk, gate to source and gate to drain voltage drops of greater than a specified voltage, for example 3.6V for a nominal 3V power supply when up to 5.5V is being externally applied to the I/O pin. In high impedance mode when the externally applied voltage at the I/O pin is sufficiently below the interface circuit supply voltage, the isolation circuit is driven to approximately the interface circuit supply voltage. In low impedance mode the isolation circuitry is disabled and the logic level at the data terminal is transmitted to the I/O pin. One embodiment of the present invention provides a buffered data path from the data terminal to the I/O pin.
摘要:
Described is a programmable logic device (PLD) with columns of DSP slices that can be cascaded to create DSP circuits of varying size and complexity. Each slice includes a mode port that receives mode control signals for dynamically altering the function and connectivity of related slices. Such alterations can occur with or without reconfiguring the PLD.
摘要:
A digital signal processing circuit including: a multiplier circuit; a plurality of multiplexers coupled to the multiplier circuit and controlled by a first opcode; and an arithmetic logic unit coupled to plurality of multiplexers and controlled by a second opcode.