公开(公告)号：US20140088312A1

公开(公告)日：2014-03-27

申请号：US14118158

申请日：2011-09-14

申请人： Dan Li ,  Xiaoping Zhou ,  Jie Liu

发明人： Dan Li ,  Xiaoping Zhou ,  Jie Liu

IPC分类号： C07F15/04 ,  C07F1/08 ,  C07F13/00 ,  C07F3/06

CPC分类号： C07F15/045 ,  B01D2253/204 ,  B01D2257/504 ,  B01J20/22 ,  B01J20/226 ,  C07F1/005 ,  C07F1/08 ,  C07F3/00 ,  C07F3/06 ,  C07F13/005

摘要： The present invention discloses zeolite metal bis(imidazole) coordination polymers and preparation method thereof. The new class of zeolite coordination polymers of the present invention is a chemical compound with the following general chemical formula {[M(Blm)]×xDMF×yC2H6O×zH2O}∞, in which when M=Zn, x=0.9, y=0, z=0; when M=Cu, x=1.2, y=0, z=0; when M=Mn, x=2.0, y=0, z=0; when M=Ni, x=0.4, y=1.2, z=1.0, Blm is 1,2-bis((5H-imidazol-4-yl)methylene)hydrazine, DMF is N,N-dimethyl formamide, H2O is water. A solvothermal method or slow diffusion is used on the compounds to obtain crystals of high purity. The coordination polymers of the present invention have good thermal stability, and have strong adsorption performance for CO2 under conditions of 0° C. and normal pressure as adsorbent materials.

摘要翻译： 本发明公开了沸石金属双（咪唑）配位聚合物及其制备方法。 本发明的新型沸石配位聚合物是具有以下一般化学式{[M（Blm）]×xDMF×yC2H6O×zH2O}∞的化合物，其中当M = Zn时，x = 0.9，y = 0，z = 0; 当M = Cu时，x = 1.2，y = 0，z = 0; 当M = Mn时，x = 2.0，y = 0，z = 0; 当M = Ni时，x = 0.4，y = 1.2，z = 1.0，Blm是1,2-双（（5H-咪唑-4-基）亚甲基）肼，DMF是N，N-二甲基甲酰胺，H 2 O是水 。 在化合物上使用溶剂热法或缓慢扩散以获得高纯度的晶体。 本发明的配位聚合物具有良好的热稳定性，在0℃和常压作为吸附材料的条件下对CO 2具有很强的吸附性能。

公开(公告)号：US08620429B2

公开(公告)日：2013-12-31

申请号：US13457630

申请日：2012-04-27

申请人： Dan Li ,  Jaeho Kim ,  Joseph M. Bocek

发明人： Dan Li ,  Jaeho Kim ,  Joseph M. Bocek

IPC分类号： A61N1/39

CPC分类号： A61N1/3621 ,  A61N1/368 ,  A61N1/3688

摘要： An implantable medical device delivers anti-tachyarrhythmia therapies including anti-tachycardia pacing (ATP). If a detected tachyarrhythmia is classified as a type suitable for treatment using ATP, the implantable medical device selects one of an atrial ATP (A-ATP) mode, a ventricular ATP (V-ATP) mode, and a concurrent atrio-ventricular ATP (concurrent AV-ATP) mode according to the characteristics of the detected tachyarrhythmia. The concurrent ATP mode is an ATP mode during which the atrial pacing pulses and the ventricular pacing pulses are delivered concurrently. In one embodiment, the concurrent AV-ATP mode includes a synchronized atrio-ventricular ATP (synchronized AV-ATP) mode during which atrial and ventricular pacing pulses are delivered synchronously and an independent atrio-ventricular ATP (independent AV-ATP) mode during which atrial and ventricular pacing pulses are delivered concurrently but timed independently.

摘要翻译： 植入式医疗装置提供抗心律失常疗法，包括抗心动过速起搏（ATP）。 如果检测到的快速性心律失常被分类为适合于使用ATP治疗的类型，则可植入医疗装置选择心房ATP（A-ATP）模式，心室ATP（V-ATP）模式和并发心室ATP 并发AV-ATP）模式根据检测到的快速性心律失常的特点。 并发ATP模式是ATP模式，其中心房起搏脉冲和心室起搏脉冲同时传递。 在一个实施方案中，并发的AV-ATP模式包括同步的心房ATP（同步的AV-ATP）模式，其中同步递送心房和心室起搏脉冲以及独立的心房ATP（独立的AV-ATP）模式，在此期间 心房和心室起搏脉冲同时传递，但可以独立计时。

公开(公告)号：US20130342023A1

公开(公告)日：2013-12-26

申请号：US13821267

申请日：2011-03-11

申请人： Dan Li ,  Yangtao Dang ,  Hui Sun ,  Depeng Diao ,  Xuetao Huang ,  Bao Liu

发明人： Dan Li ,  Yangtao Dang ,  Hui Sun ,  Depeng Diao ,  Xuetao Huang ,  Bao Liu

IPC分类号： H04B5/00

CPC分类号： H04B5/0037 ,  H02J5/005 ,  H02J7/025 ,  H02J50/10 ,  H02J50/40 ,  H02J50/80 ,  H04B5/0081

摘要： There is provided a wireless power supplying device and method. The device includes a control part and at least one transmitting part connected with the control part. The control part includes a control circuit and a power supply module. The control circuit is used to determine the power requirement of the transmitting part connected with the control part and control the power supply module to transmit an electrical signal satisfying the power requirement to the transmitting part. The transmitting part generates a magnetic field based on the electrical signal and supplies power to a load of a receiver. The wireless power supply device and method enable each coil to generate electromagnetic induction with desired power, to supply power for the receiver reasonably, and reduce the number and the complexity of the transmitting part.

摘要翻译： 提供了一种无线供电装置和方法。 该装置包括控制部分和与控制部分连接的至少一个传送部分。 控制部分包括控制电路和电源模块。 控制电路用于确定与控制部分连接的发送部分的电力需求，并控制电源模块向发送部分发送满足电力要求的电气信号。 发射部分基于电信号产生磁场，并向接收机的负载供电。 无线供电装置和方法使得每个线圈能够产生具有期望功率的电磁感应，以便合理地为接收器供电，并且减少发射部分的数量和复杂性。

公开(公告)号：US08572514B2

公开(公告)日：2013-10-29

申请号：US12642142

申请日：2009-12-18

申请人： Dan Li ,  Zhiming Li ,  Fly Wang ,  Bin Ni

发明人： Dan Li ,  Zhiming Li ,  Fly Wang ,  Bin Ni

IPC分类号： G06F3/033 ,  G09G5/00

CPC分类号： G06F3/043 ,  G06F3/03545

摘要： Methods and apparatus to provide a handheld pointer-based user interface are described herein. An example apparatus includes a wireless pointer component and one or more base components. The wireless pointer component is configured to transmit one or more human-computer interaction (HCI) signals associated with an HCI event via a first communication link. One or more base components are operatively coupled to a screen of a display to receive the one or more HCI signals from the wireless pointer component via the first communication link. Further, the one or more base components are configured to generate at least one of operating information and position information of the wireless pointer component based on the one or more HCI signals, and to transmit the at least one of operating information and position information to a processor configured to generate screen information on the screen of the display via a second communication link.

摘要翻译： 在此描述了提供基于手持式指针的用户界面的方法和装置。 示例性设备包括无线指针组件和一个或多个基本组件。 无线指针部件被配置为经由第一通信链路发送与HCI事件相关联的一个或多个人机交互（HCI）信号。 一个或多个基本组件可操作地耦合到显示器的屏幕，以经由第一通信链路从无线指针组件接收一个或多个HCI信号。 此外，一个或多个基本组件被配置为基于一个或多个HCI信号来生成无线指针组件的操作信息和位置信息中的至少一个，并且将操作信息和位置信息中的至少一个发送到 处理器，被配置为经由第二通信链路在所述显示器的屏幕上生成屏幕信息。

公开(公告)号：US08470203B2

公开(公告)日：2013-06-25

申请号：US12724252

申请日：2010-03-15

申请人： Richard B. Kaner ,  Dan Li ,  Jiaxing Huang

发明人： Richard B. Kaner ,  Dan Li ,  Jiaxing Huang

IPC分类号： H01B1/00 ,  C08G73/00 ,  B05D5/12

CPC分类号： C08G73/0266 ,  D01D5/38 ,  D01D5/40 ,  D01F6/76

摘要： A new method for forming stable polyaniline nanofiber colloids uses electrostatic repulsion to maintain dispersion of the nanofibers and prevent aggregation during synthesis of the nanofibers. The colloidal suspensions are formed directly from the reactants in solution maintained at a pH of about 1.0 to about 4.0 and a temperature of about 10° C. to about 100° C. with minimal or no stirring. Also set forth are new methods for forming ultrathin films of polyaniline nanofibers via self-assembly.

摘要翻译： 用于形成稳定的聚苯胺纳米纤维胶体的新方法使用静电排斥来保持纳米纤维的分散并防止在纳米纤维合成期间的聚集。 胶体悬浮液直接由溶液中的反应物形成，保持在约1.0至约4.0的pH和约10℃至约100℃的温度，同时最小或不搅拌。 还阐述了通过自组装形成聚苯胺纳米纤维超薄膜的新方法。

公开(公告)号：US08447390B2

公开(公告)日：2013-05-21

申请号：US13650376

申请日：2012-10-12

申请人： Dan Li ,  Arjun D. Sharma

发明人： Dan Li ,  Arjun D. Sharma

IPC分类号： A61B5/0464

CPC分类号： A61N1/3622 ,  A61N1/3627 ,  A61N1/3962

摘要： Detected changes in atrial activation can be used to discriminate between hemodynamically stable and hemodynamically unstable tachyarrhythmias.

公开(公告)号：US08412325B2

公开(公告)日：2013-04-02

申请号：US12419074

申请日：2009-04-06

申请人： Allan Charles Shuros ,  Shantha Arcot-Krishnamurthy ,  Dan Li

发明人： Allan Charles Shuros ,  Shantha Arcot-Krishnamurthy ,  Dan Li

IPC分类号： A61N1/362

CPC分类号： A61N1/3621 ,  A61N1/3906

摘要： Embodiments of the invention are related to medical devices and methods for delivery high-energy anti-tachycardia therapy to a subject, amongst other things. In an embodiment, the invention includes a medical device including a controller module configured to administer a plurality of electrical pulses to a patient in response to a detected tachycardia, the electrical pulses comprising an amplitude of greater than 3 Volts and less than 40 Volts, the controller configured to modulate the amplitude of the electrical pulses. In an embodiment, the invention includes a method of treating a tachyarrhythmia including administering a first series of electrical pulses to a patient with an implantable medical device, the electrical pulses including an amplitude of greater than 8 Volts and less than 40 Volts, the first series of electrical pulses having an interval of less than about 600 ms in between individual pulses. Other embodiments are also included herein.

摘要翻译： 本发明的实施例涉及用于向对象递送高能抗心动过速疗法的医疗装置和方法。 在一个实施例中，本发明包括医疗装置，其包括控制器模块，其被配置为响应于检测到的心动过速向患者施加多个电脉冲，所述电脉冲包括大于3伏且小于40伏的振幅， 控制器被配置为调制电脉冲的幅度。 在一个实施方案中，本发明包括治疗快速性心律失常的方法，包括用可植入医疗装置向患者施用第一系列电脉冲，所述电脉冲包括大于8伏且小于40伏特的振幅，第一系列 在各个脉冲之间具有小于约600ms的间隔的电脉冲。 本文还包括其它实施例。

公开(公告)号：US08401628B2

公开(公告)日：2013-03-19

申请号：US12478476

申请日：2009-06-04

申请人： Dan Li ,  Allan C. Shuros ,  Quan Ni ,  Aaron R. McCabe ,  Yunlong Zhang ,  Jaeho Kim

发明人： Dan Li ,  Allan C. Shuros ,  Quan Ni ,  Aaron R. McCabe ,  Yunlong Zhang ,  Jaeho Kim

IPC分类号： A61B5/024

CPC分类号： A61B5/0464 ,  A61B5/0215 ,  A61B5/0422 ,  A61B5/046 ,  A61N1/3622 ,  A61N1/3702

摘要： An apparatus comprises an implantable cardiac signal sensing circuit, configured to provide a sensed near-field depolarization signal from a ventricle and to provide a sensed a far-field intrinsic atrial signal using a far-field atrial sensing channel, and a controller circuit communicatively coupled to the cardiac signal sensing circuit. The controller circuit includes a P-wave detection module configured to detect an atrial depolarization in the sensed far-field intrinsic atrial signal and a tachyarrhythmia detection module configured to detect an episode of tachyarrhythmia using the sensed near-field depolarization signal and to determine whether the tachyarrhythmia episode is indicative of supraventricular tachycardia (SVT) using the detected atrial depolarization and the sensed near-field depolarization signal.

摘要翻译： 一种装置包括可植入心脏信号感测电路，其被配置为提供来自心室的感测的近场去极化信号，并且使用远场心房感测通道提供感测到的远场固有心房信号，以及控制器电路，其通信耦合 到心脏信号感测电路。 所述控制器电路包括P波检测模块，所述P波检测模块被配置为检测所感测的远场固有心房信号中的心房去极化，以及快速性心律失常检测模块，其被配置为使用所感测的近场去极化信号来检测快速性心律失常发作，并且确定 快速性心律失常发作指示使用检测到的心房去极化和感测的近场去极化信号的室上性心动过速（SVT）。

公开(公告)号：US20120296383A1

公开(公告)日：2012-11-22

申请号：US13569208

申请日：2012-08-08

申请人： Dan Li

发明人： Dan Li

IPC分类号： A61N1/365 ,  A61N1/39

CPC分类号： A61N1/3621 ,  A61N1/3605 ,  A61N1/36114 ,  A61N1/36564 ,  A61N1/3962

摘要： Various system embodiments comprise at least one sensor input adapted to receive at least one sensed signal associated with a tachyarrhythmia, a feature set extractor adapted to extract at least two features from the at least one sensed signal associated with the tachyarrhythmia, a feature set generator adapted to form a feature set using the at least two features extracted by the feature set extractor, at least one generator adapted for use to selectively apply an anti-tachycardia pacing (ATP) therapy and a neural stimulation (NS) therapy, and a controller adapted to respond to the feature set. The controller is adapted to initiate the NS therapy when the feature set corresponds to criteria for applying the NS therapy to modify the tachyarrhythmia, and initiate the ATP therapy to terminate the modified tachyarrhythmia. Other aspects and embodiments are provided herein.

摘要翻译： 各种系统实施例包括适于接收与快速性心律失常相关联的至少一个感测信号的至少一个传感器输入，适于从与快速性心律失常相关联的至少一个感测信号中提取至少两个特征的特征集提取器，适于 以使用由所述特征集提取器提取的所述至少两个特征来形成特征集合，适于用于选择性地应用抗心动过速起搏（ATP）治疗和神经刺激（NS）治疗）的至少一个发生器，以及适于 以响应功能集。 当特征集合对应于应用NS治疗来修改快速性心律失常的标准时，控制器适于启动NS治疗，并且启动ATP治疗以终止改变的快速性心律失常。 本文提供了其它方面和实施例。

公开(公告)号：US08301267B2

公开(公告)日：2012-10-30

申请号：US12876426

申请日：2010-09-07

申请人： Allan C. Shuros ,  Dan Li ,  Krzysztof Z. Siejko ,  John H. Tangren

发明人： Allan C. Shuros ,  Dan Li ,  Krzysztof Z. Siejko ,  John H. Tangren

IPC分类号： A61N1/05

CPC分类号： A61B5/02158 ,  A61B5/02133 ,  A61B5/02405 ,  A61N1/36514 ,  A61N1/36578

摘要： An apparatus comprises an implantable sensor and a signal analyzer circuit communicatively coupled to the implantable sensor. The implantable sensor is configured for coupling to an implantable lead and the implantable sensor provides an electrical vibration sensor signal representative of mechanical vibration of the implantable lead. The signal analyzer circuit is configured to determine a baseline of the vibration sensor signal, detect a change in the vibration sensor signal from the baseline vibration sensor signal, and provide an indication of the change to a user or process.

摘要翻译： 一种装置包括可植入传感器和通信地耦合到可植入传感器的信号分析器电路。 可植入传感器被配置为联接到可植入引线，并且可植入传感器提供表示可植入引线的机械振动的电振动传感器信号。 信号分析器电路被配置为确定振动传感器信号的基线，从基线振动传感器信号检测振动传感器信号的变化，并且向用户或过程提供变化的指示。