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    Microstructure separation filters
    32.
    发明授权
    Microstructure separation filters 有权

    公开(公告)号：US11110375B2

    公开(公告)日：2021-09-07

    申请号：US16161678

    申请日：2018-10-16

    Applicant: Imagine TF, LLC

    Inventor： Brian Edward Richardson

    IPC: B01D15/22 ,  B01D67/00 ,  B01D69/02 ,  B01L3/00 ,  B01L9/00 ,  G01N30/60 ,  B01D15/12

    Abstract: Microstructure separation filters are provided herein, as well as chromatography and other separation devices. An exemplary filter device includes a microstructure filter has a plurality of layers of alternating sacrificial and/or structural material which have been etched to create inlet channels and outlet channels. Adjacent ones of the inlet channels and the outlet channels are spaced apart from one another by cross channels that filter a fluid from the inlet channels to the outlet channels. The cross channels include filter features formed by etching away of a portion of the layers. The device also includes a housing configured to receive the microstructure filter.

    High pressure valve with multi-piece stator assembly
    35.
    发明授权
    High pressure valve with multi-piece stator assembly 有权

    公开(公告)号：US11054054B2

    公开(公告)日：2021-07-06

    申请号：US15962748

    申请日：2018-04-25

    Applicant: IDEX Health & Science LLC

    Inventor： Quan Liu ,  Jeremy Hayes

    IPC: G01N30/20 ,  F16K31/04 ,  F16K25/00 ,  F16K11/074 ,  B01D15/22

    Abstract: A valve for use with liquid chromatography or other analytical systems may include a separate and removable stator plate. The stator plate may be a with a multi-piece stator plate with different layers. A mounting device mounting device may be adapted to engage the stator plate. The mounting plate may include a plurality of ports for fluidic connections in fluid communication with fluid passageways in the stator plate. Liquid chromatography elements, such as a packed chromatography column, a sample loop, or an electronic device may be formed on one or more layers of the stator plate. A first stator plate may be removed from a valve and replaced by a second stator having additional or different liquid chromatography elements than the first stator plate.

    LIQUID CHROMATOGRAPHY TECHNIQUE
    37.
    发明申请
    LIQUID CHROMATOGRAPHY TECHNIQUE 有权

    公开(公告)号：US20210170305A1

    公开(公告)日：2021-06-10

    申请号：US17177770

    申请日：2021-02-17

    Applicant: SILCOTEK CORP.

    Inventor： Jesse BISCHOF ,  Lucas D. PATTERSON ,  Gary BARONE ,  Min YUAN ,  David A. SMITH

    IPC: B01D15/22 ,  B01D15/20 ,  B01D15/16 ,  G01N30/36 ,  G01N30/56 ,  G01N30/30 ,  G01N30/02

    Abstract: Liquid chromatography techniques are disclosed. Specifically, the liquid chromatography technique includes providing a liquid chromatography system having a coated metallic fluid-contacting element, and transporting a fluid to contact the coated metallic fluid-contacting element. Conditions for the transporting of the fluid are selected from the group consisting of the temperature of the fluid being greater than 150° C., pressure urging the fluid being greater than 60 MPa, the fluid having a protein-containing analyte incompatible with one or both of titanium and polyether ether ketone, the fluid having a chelating agent incompatible with the one or both of the titanium or the polyether ether ketone, and combinations thereof

    Multi-column separation apparatus and method
    38.
    发明授权
    Multi-column separation apparatus and method 有权

    公开(公告)号：US11022586B2

    公开(公告)日：2021-06-01

    申请号：US15113075

    申请日：2015-01-21

    Applicant: National Nuclear Laboratory Limited

    Inventor： Steven J. Stanley ,  Thomas O. Myers

    IPC: G01N30/46 ,  B01L3/00 ,  G01N30/60 ,  G21F9/30 ,  G21F9/34 ,  G21F9/12 ,  B01D15/22 ,  G01N1/40 ,  G01N30/74

    Abstract: The invention provides an apparatus and system for the separation and optional analysis of the components of a sample of material, the apparatus and system comprising a cartridge comprising: at least one sample inlet port, at least one resin inlet port and a multiplicity of reagent and purge fluid input ports which are fluidically connected via a multiplicity of control valves to a multiplicity of chromatographic columns which are fluidically connected together in series; and a multiplicity of outlet ports wherein each outlet port additionally comprises an outlet valve which is adapted to control the flow of fluid through said outlet ports; wherein each of said multiplicity of chromatographic columns is aligned with one of said multiplicity of outlet ports so as to allow for fluid flow from said column through said outlet port. The system optionally additionally facilitates the analysis of the components. The invention additionally provides a method for the separation of the components of a sample of material which comprises the use of the apparatus and system of the invention. The apparatus, system and method of the invention are advantageously applied to the separation and analysis of radioactive materials.

    LIQUID CHROMATOGRAPHY TECHNIQUE
    40.
    发明申请
    LIQUID CHROMATOGRAPHY TECHNIQUE 有权

    公开(公告)号：US20210101092A1

    公开(公告)日：2021-04-08

    申请号：US16971216

    申请日：2019-02-22

    Applicant: SILCOTEK CORP.

    Inventor： Jesse BISCHOF ,  Lucas D. PATTERSON ,  Gary BARONE ,  Min YUAN ,  David A. SMITH

    IPC: B01D15/22 ,  G01N30/30 ,  G01N30/36 ,  G01N30/56 ,  B01D15/20 ,  B01D15/16

    Abstract: LC techniques are disclosed. The LC technique includes providing a liquid chromatography system having a coated metallic fluid-contacting element, and transporting a fluid to contact the coated metallic fluid contacting element. Conditions for the transporting of the fluid are selected from the group consisting of the temperature of the fluid being greater than 150 degree Celsius, pressure urging the fluid being greater than 60 MPa, the fluid having a protein-containing analyte incompatible with one of titanium and polyether ether ketone, the fluid having a chelating agent incompatible with the one or both of the titanium or the polyether ether ketone.

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