公开(公告)号：US20080315103A1

公开(公告)日：2008-12-25

申请号：US11946318

申请日：2007-11-28

Applicant: Yoshitake Yamamoto

Inventor： Yoshitake Yamamoto

IPC: G01J5/02

CPC classification number: G01J3/45 ,  G01J3/02 ,  G01J3/027

Abstract: Disclosed is a Fourier transform infrared spectrophotometer, which comprises: a main interferometer section including a beam splitter, a fixed mirror, a movable mirror, and a phase plate disposed between the beam splitter and the fixed mirror; a control interferometer section having a quadrature control system for calculating a position of the movable mirror; a center-burst-position detection section operable, based on an input of interference signals and interferograms, to subject respective intensities of the interferograms to an addition processing while correcting a positional deviation of the movable mirror, so as to obtain a cumulative interferogram, and detecting a center burst position having a maximum intensity value in the cumulative interferogram; a center-burst-position storage section operable to store the detected center burst position; and a measurement-start-position determination section operable, based on the stored center burst position, to determine a measurement start position of the movable mirror during the measurement operation.

Abstract translation: 公开了一种傅里叶变换红外分光光度计，其包括：主干涉仪部分，包括分束器，固定镜，可移动反射镜和设置在分束器和固定镜之间的相位板; 控制干涉仪部分，具有用于计算可移动反射镜的位置的正交控制系统; 中央突发位置检测部，其基于干涉信号和干涉图的输入，在校正可动镜的位置偏差的同时对干涉图的各个强度进行加法处理，以获得累积干涉图;以及 检测累积干涉图中具有最大强度值的中心脉冲串位置; 中央突发位置存储部分，用于存储检测到的中心突发位置; 以及测量开始位置确定部，其基于所存储的中心突发位置可操作，以在测量操作期间确定可移动镜的测量开始位置。

公开(公告)号：US07394546B2

公开(公告)日：2008-07-01

申请号：US11438864

申请日：2006-05-22

Applicant: Andrei B. Vakhtin ,  Daniel J. Kane ,  Kristen A. Peterson

Inventor： Andrei B. Vakhtin ,  Daniel J. Kane ,  Kristen A. Peterson

IPC: G01B9/02 ,  G01J3/45

CPC classification number: G01J3/45 ,  G01B9/02004 ,  G01B9/0201 ,  G01B9/02044 ,  G01B9/02081 ,  G01B9/02091 ,  G01B2290/45

Abstract: An apparatus and method for differential spectral interferometry comprising providing an interferometer comprising a light source; employing an element to provide a dithered relative phase shift between target and reference arms of the interferometer, detecting output from the interferometer, demodulating signals received from the detector at different multiples of the dither frequencies, generating more than one real-valued interferograms from demodulated signals, and using the real-valued interferograms to obtain the complex spectral interferogram.

Abstract translation: 一种用于差分光谱干涉测量的装置和方法，包括提供包括光源的干涉仪; 使用元件在干涉仪的目标和参考臂之间提供抖动的相对相移，检测来自干涉仪的输出，解调从抖动频率的不同倍数从检测器接收的信号，从解调信号产生多于一个的实数干涉图 ，并使用实数干涉图获得复谱干涉图。

公开(公告)号：US20080147331A1

公开(公告)日：2008-06-19

申请号：US11955685

申请日：2007-12-13

Applicant: Kenichi Akao ,  Seiichi Kashiwabara ,  Toshiyuki Nagoshi

Inventor： Kenichi Akao ,  Seiichi Kashiwabara ,  Toshiyuki Nagoshi

IPC: G01N31/00

CPC classification number: G01J3/45 ,  G01N21/45 ,  G01N2021/1725 ,  G01N2021/3595

Abstract: An irreversible-reaction measurement method comprising: a step in which a perturbation is applied to one of the divided portions of a measurement sample placed in a light path of a Fourier-transform spectrophotometer to cause an irreversible-reaction while a mirror of the spectrophotometer remains at a data point; a step in which interferogram is detected from the sample portion placed in the path at predetermined time intervals after the application of the perturbation; a step in which the mirror moves to and remains at the next data point after the reaction of the sample portion reaches an end point; a step in which the sample portion placed in the light path is changed to the next sample portion each time the mirror moves to the next data point; and a step in which the irreversible-reaction of the measurement sample is analyzed in accordance with the interferogram obtained by repeating the steps.

Abstract translation: 一种不可逆反应测定方法，其特征在于，包括以下步骤：在分光光度计的反射镜保留在傅里叶变换分光光度计的光路内的测定样品的分割部分之一中产生不可逆反应的步骤 在数据点; 在施加扰动之后，以预定时间间隔从放置在路径中的样本部分检测干涉图的步骤; 在样品部分的反应达到终点之后，镜子移动并保持在下一个数据点的步骤; 每当镜子移动到下一个数据点时，将放置在光路中的样本部分改变为下一个采样部分的步骤; 以及根据通过重复该步骤获得的干涉图来分析测量样品的不可逆反应的步骤。

公开(公告)号：US20080130008A1

公开(公告)日：2008-06-05

申请号：US11792977

申请日：2005-12-15

Applicant: Etienne Le Coarer ,  Pierre Benech

Inventor： Etienne Le Coarer ,  Pierre Benech

IPC: G01J3/45

CPC classification number: G01J3/45 ,  G01J3/0205

Abstract: An interferential spectroscopy detector including a waveguide having an input side and a mirror on an opposite side, and means for detecting electromagnetic rays delivering an electric signal as a function of local intensity of an electromagnetic wave, detection being produced between an input side and the mirror.

Abstract translation: 一种干涉光谱检测器，包括具有相对侧的输入侧和反射镜的波导，以及用于检测作为电磁波的局部强度的函数的电信号的电磁射线的装置，在输入侧和反射镜之间产生检测 。

公开(公告)号：US20080037009A1

公开(公告)日：2008-02-14

申请号：US11826744

申请日：2007-07-18

Applicant: Arno Simon

Inventor： Arno Simon

IPC: G01N21/00

CPC classification number: G01N21/3563 ,  G01J3/02 ,  G01J3/0262 ,  G01J3/0291 ,  G01J3/0294 ,  G01J3/45 ,  G01N2021/3595

Abstract: A spectrometer system (1) comprising an IR (infrared) spectrometer (2) and an IR microscope (3), wherein a sample (42) and a first detector (21; 31) are provided in the IR microscope (3), wherein the IR microscope (3) is designed such that during measurement, the sample (42) is imaged on the first detector (21; 31) via an intermediate focus (44), is characterized in that at least one second detector (24, 25; 33) is provided whose detector surface (26, 27; 34) extends parallel to the detector surface (22; 32) of the first detector (21; 31), the detector surface (26, 27; 34) of the at least one second detector (24, 25; 33) is at least 5 times larger than the detector surface (22; 32) of the first detector (21; 31), and the first (21; 31) and the at least one second detector (24, 25; 33) are disposed directly next to each other, wherein the detector surface (26, 27; 34) of the at least one second detector (24, 25; 33) largely surrounds the detector surface (22; 32) of the first detector (21, 31), and the first detector (21; 31) can be read out independently of the at least one second detector (24, 25; 33). The inventive spectrometer system yields a good signal-to-noise ratio both for large and small selected sample areas.

Abstract translation: 一种包括IR（红外）光谱仪（2）和IR显微镜（3）的光谱仪系统（1），其中在所述IR显微镜（3）中设置有样品（42）和第一检测器（21; 31），其中 红外显微镜（3）被设计成使得在测量期间，样品（42）经由中间焦点（44）成像在第一检测器（21; 31）上，其特征在于至少一个第二检测器 ; 33），其检测器表面（26,27; 34）平行于所述第一检测器（21; 31）的检测器表面（22; 32）延伸，所述检测器表面（26,27; 34）至少 一个第二检测器（24,25; 33）比第一检测器（21; 31）的检测器表面（22; 32）大至少5倍，第一检测器（21; 31）和至少一个第二检测器 （24,25; 33）彼此直接布置，其中所述至少一个第二检测器（24,25; 33）的检测器表面（26,27; 34）主要围绕所述检测器 表面（22; 可以独立于至少一个第二检测器（24,25; 33）读出第一检测器（21,31）和第一检测器（21; 31）。 本发明的光谱仪系统对于大和小的选定样品区域都产生良好的信噪比。

公开(公告)号：US07330268B2

公开(公告)日：2008-02-12

申请号：US11478804

申请日：2006-06-30

Applicant: Kenneth J. Pettipiece ,  William B. Amos

Inventor： Kenneth J. Pettipiece ,  William B. Amos

IPC: G01B9/02

CPC classification number: G01J3/2823 ,  G01J3/45 ,  G01J2003/2866

Abstract: A method and apparatus for an improved spectral imaging system is provided. The system is capable of measuring the fluorescence, luminescence, or absorption at selected locations on a sample plate. The emissions detection subassembly can tune to any wavelength within a continuum of wavelengths utilizing an interferometric spectral discriminator. The interferometric spectral discriminator creates an interferogram from which the wavelength spectra for each pixel of the array can be calculated, typically using Fourier transform analysis. In one aspect, the chromatic accuracy of the system is calibrated using a calibration slit placed in the input aperture of the input relay lens but outside of the sample image. The slit is illuminated using a source of known wavelength. The fringe count versus the wavelength of the slit illumination source is monitored and used to calibrate the spectral discriminator. In another aspect, a transparent optic is included in the interferometric spectral discriminator that can be inserted into the beam path whenever a monochrome image of the sample is required. The optic produces a large offset in the legs of the interferometer resulting in the fringe density becoming too large to resolve by the individual pixels of the detector array. In another aspect, the interferometric spectral discriminator includes a polarizing beam splitter. The polarizing beam splitter preferentially reflects one polarization while preferentially transmitting a second polarization, thus achieving improved efficiency while minimizing ghosting. In another aspect, a metaphase finder is used to locate areas of interest. The sample plate containing the material of interest is illuminated with light of a wavelength determined to preferentially scatter from objects the size of the metaphase spreads. The intensity of the scattered light versus the location on the sample plate is monitored and used to locate the areas of interest. Preferably the sample plate is also illuminated by light of a second wavelength which is not preferentially scattered by the objects of interest, thus representing the background scatter. By subtracting the background scatter from the primary scattered light, improved object discrimination is achieved.

公开(公告)号：US20070291255A1

公开(公告)日：2007-12-20

申请号：US11845580

申请日：2007-08-27

Applicant: David Larsen ,  Zhi Xu

Inventor： David Larsen ,  Zhi Xu

IPC: G01N21/00

CPC classification number: G01J3/02 ,  G01J3/0262 ,  G01J3/0286 ,  G01J3/0291 ,  G01J3/42 ,  G01J3/45 ,  G01J2003/425 ,  G01N21/274 ,  G01N21/31 ,  G01N2021/3137 ,  G01N2201/0227 ,  G01N2201/127

Abstract: Increasing signal to noise ratio in optical spectra obtained by spectrophotometers. An interferometer introduces interference effects into a source light beam. A dual beam configuration splits the source beam having the interference effects into a reference beam and a sample beam. The reference beam interacts with a reference substance and is detected by a reference detector. The sample beam interacts with a sample substance and is detected by a sample detector. An optical spectra of the sample is based on the difference between the detected reference beam and the detected sample beam.

Abstract translation: 通过分光光度计获得的光谱增加信噪比。 干涉仪将干扰效应引入源光束。 双光束配置将具有干涉效应的源光束分解成参考光束和样本光束。 参考光束与参考物质相互作用，并由参考检测器检测。 样品束与样品物质相互作用，并由样品检测器检测。 样品的光谱基于检测到的参考光束和检测到的样品光束之间的差异。

公开(公告)号：US20070025638A1

公开(公告)日：2007-02-01

申请号：US11396935

申请日：2006-04-03

Applicant: Aydogan Ozcan ,  Michel Digonnet ,  Gordon Kino

Inventor： Aydogan Ozcan ,  Michel Digonnet ,  Gordon Kino

IPC: G06K9/36

CPC classification number: G06E3/003 ,  G01J3/45 ,  G01J11/00

Abstract: A method processes an optical image. The method includes providing a measured magnitude of the Fourier transform of a two-dimensional complex transmission function. The method further includes providing an estimated phase term of the Fourier transform of the two-dimensional complex transmission function. The method further includes multiplying the measured magnitude and the estimated phase term to generate an estimated Fourier transform of the two-dimensional complex transmission function. The method further includes calculating an inverse Fourier transform of the estimated Fourier transform, wherein the inverse Fourier transform is a spatial function. The method further includes calculating an estimated two-dimensional complex transmission function by applying at least one constraint to the inverse Fourier transform.

Abstract translation: 一种处理光学图像的方法。 该方法包括提供二维复数传输函数的傅立叶变换的测量幅度。 该方法还包括提供二维复数传输函数的傅立叶变换的估计相位项。 该方法还包括将测量的幅度和估计的相位项相乘以产生二维复数传输函数的估计傅里叶变换。 该方法还包括计算傅立叶逆变换的傅立叶逆变换，其中逆傅里叶变换是空间函数。 该方法还包括通过对傅里叶逆变换应用至少一个约束来计算估计的二维复传输函数。

公开(公告)号：US07145713B2

公开(公告)日：2006-12-05

申请号：US11179765

申请日：2005-07-12

Applicant: Tiejun Chang ,  Mingzhen Tian ,  William R. Babbitt ,  Kristian Merkel

Inventor： Tiejun Chang ,  Mingzhen Tian ,  William R. Babbitt ,  Kristian Merkel

IPC: G02F2/00

CPC classification number: G01J3/02 ,  G01J3/0264 ,  G01J3/28 ,  G01J3/2889 ,  G01J3/4338 ,  G01J3/45

Abstract: Techniques for recovering optical spectral features include receiving a detected time series that represents a temporally varying intensity of an optical signal. The optical signal is formed in response to an interaction between a target optical spectrum and a chirped optical field. The chirped optical field is an optical field that has a monochromatic frequency that varies in time. The target optical spectrum is an optical frequency dependent optical property of a material or device. A phase correction factor is determined based only on one or more properties of the chirped optical field. The detected time series is corrected based on the phase correction factor to produce an output time series that reproduces in time a shape of the target spectrum in frequency. These techniques allow for fast measurement of spectral features and eliminate the need for prior knowledge of the target optical spectrum to adjust the chirp rate.

公开(公告)号：US20060241491A1

公开(公告)日：2006-10-26

申请号：US11074307

申请日：2005-03-07

Applicant: Sylvie Bosch-Charpenay ,  Barbara Marshik-Geurts ,  Leonard Kamlet ,  Jorge Neira ,  David Marran

Inventor： Sylvie Bosch-Charpenay ,  Barbara Marshik-Geurts ,  Leonard Kamlet ,  Jorge Neira ,  David Marran

IPC: A61B6/00

CPC classification number: G01J3/45

Abstract: A method and apparatus is disclosed for signal spectrometry using an improved apodization function. Such method and apparatus involve (i) obtaining sample and reference time domain waveforms; (ii) applying sample and reference apodization waveforms to the sample and reference time domain waveforms, such that substantially same weight is applied to corresponding substantially coextensive regions of the sample and reference time domain waveforms, (iii) transforming the sample and reference apodized waveforms from the time domain into the frequency domain; and (iv) generating referenced spectral analysis waveform for signal analysis from a ratio of the transformed sample and reference frequency spectra, the spectral analysis waveform substantially excluding frequencies associated with the corresponding substantially coextensive regions of the apodized sample and reference time domain waveforms.