公开(公告)号：US20180326376A1

公开(公告)日：2018-11-15

申请号：US15775245

申请日：2016-11-09

Applicant: HORIBA ABX SAS

Inventor： Florent BEAUDUCEL ,  Philippe BENEZETH

IPC: B01F9/00 ,  B01L3/00

CPC classification number: B01F9/002 ,  B01L3/5025 ,  B01L2300/021 ,  C12Q1/68 ,  G01N35/00732 ,  G01N35/0092 ,  G01N35/0099 ,  G01N35/1072 ,  G01N35/1083 ,  G01N2001/002 ,  G01N2035/00524 ,  G01N2035/041 ,  G01N2035/0412 ,  G01N2035/042 ,  G01N2035/0472 ,  G01N2035/0493 ,  G01N2035/1058

Abstract: A device for agitating and collecting biological liquid samples comprises an agitator of racks of tubes, a sampling apparatus capable of collecting a biological liquid sample in a tube, and a changer capable of gripping a tube on a rack received in the agitator and moving it to the sampling apparatus. The agitator is capable of agitating at least three racks simultaneously, and the device also comprises a scheduler capable of determining destination data for a tube and destination data for the rack which receives this tube, and of determining for each tube a final location based on the destination data of the tube and the destination data of the racks received in the device, which final location designates a rack, received on the agitator and a position on this rack and can be different from the location of the tube when the rack that received it has been introduced into the device, and arranged to control the changer in order to grip a tube, present it to the sampling apparatus and replace it after sampling at the final location.

公开(公告)号：US20180080760A1

公开(公告)日：2018-03-22

申请号：US15560763

申请日：2016-03-23

Applicant: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES ,  HORIBA ABX SAS

Inventor： Cedric ALLIER ,  Pierre BLANDIN ,  Anais ALI CHERIF ,  Lionel HERVE

IPC: G01B11/24 ,  G01N21/47

CPC classification number: G01N15/1429 ,  G01N15/1463 ,  G01N21/453 ,  G01N21/4788 ,  G01N33/49 ,  G01N2015/1454 ,  G01N2015/1488 ,  G03H1/0443 ,  G03H1/0866 ,  G03H2001/0447 ,  G03H2001/0883 ,  G06K9/00147 ,  G06T7/0012

Abstract: A method for identifying a particle contained in a sample, including illuminating the sample using a light source, the light source producing an incident light wave propagating toward the sample, then acquiring, using a matrix-array photodetector, an image of the sample, the sample being placed between the light source and the photodetector such that the matrix-array photodetector is exposed to a light wave that is the result of interference between the incident light wave and a diffraction wave produced by each particle. The method further includes applying a numerical reconstruction algorithm to the image acquired by the photodetector, to estimate a characteristic quantity of the light wave reaching the detector, at a plurality of distances from the detector. The variation in the characteristic quantity as a function of distance allows the particle to be identified.

公开(公告)号：US20160361718A1

公开(公告)日：2016-12-15

申请号：US15121727

申请日：2015-02-20

Applicant: HORIBA ABX SAS

Inventor： Nathalie HENON ,  Florent BEAUDUCEL

IPC: B01L3/00 ,  F16K11/074 ,  G01N1/10

CPC classification number: B01L3/567 ,  B01L2400/0622 ,  B01L2400/0644 ,  F16K11/074 ,  F16K11/166 ,  G01N1/10 ,  G01N35/1097

Abstract: The invention relates to a sampling valve and to a device equipped with such a valve notably allowing haematogy Ineasttrenreaat to be taken from a blood sample. The valve comprise two external parts, one internal part clamped between said exterrtal parts, and means for regulating the relative angular position of these parts about to axis of rotation. The mienial part has opposite surfaces pressing in a sealed and sliding manner against adjacent surfaces of the external parts. The external parts comprise orifices, loops and ducts, said loops and said ducts being arranged in such a way as to communicate selectively with orifices passing through the internal part. The valve parts have no aliquot return groove or recess or labyrinth, thereby eliminating regions of turbulence. The valve is characterized in that two of the parts are able to rotate about the axis of rotation with respect to one of the said pans which is stationary, the rotary parts preferably being the external parts. The sampling valve also makes it possible to form calibrated volumes of a sample taken in the loops and/or the orifices of the internal pan.

Abstract translation: 本发明涉及采样阀和配备有这种阀的装置，其特征在于允许血液样品从血液样品中取出。 阀包括两个外部部件，一个内部部件夹在所述外部部件之间，以及用于调节这些部件相对于旋转轴线的相对角度位置的装置。 该部件具有相对的表面以相对于外部部件的相邻表面的密封和滑动的方式进行压制。 外部部件包括孔，环和管道，所述环和所述管道以这样的方式布置，以便选择性地通过穿过内部部件的孔。 阀部件没有等分回流槽或凹槽或迷宫，从而消除湍流区域。 该阀的特征在于，两个部件能够相对于静止的所述盘之一旋转轴线旋转，旋转部件优选地是外部部件。 采样阀还可以形成采集在内部盘的回路和/或孔口中的样品的校准体积。

公开(公告)号：US20160153972A1

公开(公告)日：2016-06-02

申请号：US14775886

申请日：2014-03-11

Applicant: Jérôme BIBETTE ,  HORIBA ABX SAS

Inventor： Aurelien DAYNES ,  Gilles CAUET ,  Jean-Philippe GINEYS ,  Philippe NERIN ,  Jerome BIBETTE

IPC: G01N33/537

CPC classification number: G01N33/537 ,  G01N33/54326 ,  G01N33/558 ,  G01N33/56966 ,  G01N2333/4737 ,  G01N2446/00

Abstract: The present invention relates to a flow assay method in a liquid medium for an object (or element) of interest via the formation of aggregates of particles that are surface-functionalized by at least one functionalizing molecule, or receptor, specific for said object of interest.

Abstract translation: 本发明涉及通过形成由至少一个功能化分子或受体表征官能化的所述目的物（或元件）的目标（或元件）的液体介质中的流动测定方法 。

公开(公告)号：US20160151776A1

公开(公告)日：2016-06-02

申请号：US14905779

申请日：2014-07-17

Applicant: HORIBA ABX SAS

Inventor： Didier CREMIEN ,  Damien ISEBE

IPC: B01L3/02

Abstract: The present application relates to: (i) a sampler device for taking a sample of biological fluid, which comprises a capillary component, and a base rigidly connected to said capillary component and provided with a first connector capable of being reversibly attached in a leaktight manner to a second connector of a dispensing device; (ii) a dispensing device which also comprises means for transferring diluting fluid which open into said second connector. The application also relates to a biological analysis apparatus implementing the sampler and dispensing devices and to a method for sampling and dispensing a biological fluid.

Abstract translation: 本申请涉及：（i）用于取样生物流体样本的取样器装置，其包括毛细管部件，以及与所述毛细管部件刚性连接的基部，并且具有能够以密封方式可逆地连接的第一连接器 到分配装置的第二连接器; （ii）分配装置，其还包括用于传送打开到所述第二连接器中的稀释流体的装置。 该应用还涉及实施采样器和分配装置的生物分析装置以及用于取样和分配生物流体的方法。