Methods for administering tumor vaccines
    49.
    发明申请
    Methods for administering tumor vaccines 审中-公开
    肿瘤疫苗的使用方法

    公开(公告)号:US20080124354A1

    公开(公告)日:2008-05-29

    申请号:US11822870

    申请日:2007-07-10

    摘要: The present invention provides methods of inducing an immune response in a subject against a protein of interest and treating and suppressing a formation of a tumor comprising a tumor-associated protein, comprising sequential administration of fragments of the protein. The present invention also provides Her-2 protein fragments, recombinant peptides comprising same, nucleotide molecules encoding same, recombinant vaccine vectors and immunogenic compositions comprising same, and methods for inducing immune response and treating cancer, comprising same.

    摘要翻译: 本发明提供了针对目的蛋白质诱导受试者的免疫应答的方法,并且治疗和抑制包含肿瘤相关蛋白的肿瘤的形成,包括顺序施用蛋白质的片段。 本发明还提供了Her-2蛋白片段,包含其的重组肽,编码它们的核苷酸分子,重组疫苗载体和包含其的免疫原性组合物,以及诱导免疫应答和治疗癌症的方法。